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Items: 21


Neisseria gonorrhoeae PBP3 and PBP4 Facilitate NOD1 Agonist Peptidoglycan Fragment Release and Survival in Stationary Phase.

Schaub RE, Perez-Medina KM, Hackett KT, Garcia DL, Dillard JP.

Infect Immun. 2019 Jan 24;87(2). pii: e00833-18. doi: 10.1128/IAI.00833-18. Print 2019 Feb.


A Single Dual-Function Enzyme Controls the Production of Inflammatory NOD Agonist Peptidoglycan Fragments by Neisseria gonorrhoeae.

Lenz JD, Hackett KT, Dillard JP.

MBio. 2017 Oct 17;8(5). pii: e01464-17. doi: 10.1128/mBio.01464-17.


Neisseria gonorrhoeae Lytic Transglycosylases LtgA and LtgD Reduce Host Innate Immune Signaling through TLR2 and NOD2.

Knilans KJ, Hackett KT, Anderson JE, Weng C, Dillard JP, Duncan JA.

ACS Infect Dis. 2017 Sep 8;3(9):624-633. doi: 10.1021/acsinfecdis.6b00088. Epub 2017 Jun 21.


Two lytic transglycosylases in Neisseria gonorrhoeae impart resistance to killing by lysozyme and human neutrophils.

Ragland SA, Schaub RE, Hackett KT, Dillard JP, Criss AK.

Cell Microbiol. 2017 Mar;19(3). doi: 10.1111/cmi.12662. Epub 2016 Nov 3.


Amidase Activity of AmiC Controls Cell Separation and Stem Peptide Release and Is Enhanced by NlpD in Neisseria gonorrhoeae.

Lenz JD, Stohl EA, Robertson RM, Hackett KT, Fisher K, Xiong K, Lee M, Hesek D, Mobashery S, Seifert HS, Davies C, Dillard JP.

J Biol Chem. 2016 May 13;291(20):10916-33. doi: 10.1074/jbc.M116.715573. Epub 2016 Mar 16.


Structural and functional features of a developmentally regulated lipopolysaccharide-binding protein.

Krasity BC, Troll JV, Lehnert EM, Hackett KT, Dillard JP, Apicella MA, Goldman WE, Weiss JP, McFall-Ngai MJ.

MBio. 2015 Oct 13;6(5):e01193-15. doi: 10.1128/mBio.01193-15.


Targeted mutagenesis of intergenic regions in the Neisseria gonorrhoeae gonococcal genetic island reveals multiple regulatory mechanisms controlling type IV secretion.

Ramsey ME, Bender T, Klimowicz AK, Hackett KT, Yamamoto A, Jolicoeur A, Callaghan MM, Wassarman KM, van der Does C, Dillard JP.

Mol Microbiol. 2015 Sep;97(6):1168-85. doi: 10.1111/mmi.13094. Epub 2015 Jul 17.


TraK and TraB are conserved outer membrane proteins of the Neisseria gonorrhoeae Type IV secretion system and are expressed at low levels in wild-type cells.

Ramsey ME, Hackett KT, Bender T, Kotha C, van der Does C, Dillard JP.

J Bacteriol. 2014 Aug 15;196(16):2954-68. doi: 10.1128/JB.01825-14. Epub 2014 Jun 9.


Peptidoglycan fragment release from Neisseria meningitidis.

Woodhams KL, Chan JM, Lenz JD, Hackett KT, Dillard JP.

Infect Immun. 2013 Sep;81(9):3490-8. doi: 10.1128/IAI.00279-13. Epub 2013 Jul 8.


Mating pair formation homologue TraG is a variable membrane protein essential for contact-independent type IV secretion of chromosomal DNA by Neisseria gonorrhoeae.

Kohler PL, Chan YA, Hackett KT, Turner N, Hamilton HL, Cloud-Hansen KA, Dillard JP.

J Bacteriol. 2013 Apr;195(8):1666-79. doi: 10.1128/JB.02098-12. Epub 2013 Feb 1.


Characterization of the single stranded DNA binding protein SsbB encoded in the Gonoccocal Genetic Island.

Jain S, Zweig M, Peeters E, Siewering K, Hackett KT, Dillard JP, van der Does C.

PLoS One. 2012;7(4):e35285. doi: 10.1371/journal.pone.0035285. Epub 2012 Apr 19.


The lytic transglycosylases of Neisseria gonorrhoeae.

Chan YA, Hackett KT, Dillard JP.

Microb Drug Resist. 2012 Jun;18(3):271-9. doi: 10.1089/mdr.2012.0001. Epub 2012 Mar 20. Review.


Prevalence and detailed mapping of the gonococcal genetic island in Neisseria meningitidis.

Woodhams KL, Benet ZL, Blonsky SE, Hackett KT, Dillard JP.

J Bacteriol. 2012 May;194(9):2275-85. doi: 10.1128/JB.00094-12. Epub 2012 Feb 24.


Neisseria gonorrhoeae virulence factor NG1686 is a bifunctional M23B family metallopeptidase that influences resistance to hydrogen peroxide and colony morphology.

Stohl EA, Chan YA, Hackett KT, Kohler PL, Dillard JP, Seifert HS.

J Biol Chem. 2012 Mar 30;287(14):11222-33. doi: 10.1074/jbc.M111.338830. Epub 2012 Feb 13.


New complementation constructs for inducible and constitutive gene expression in Neisseria gonorrhoeae and Neisseria meningitidis.

Ramsey ME, Hackett KT, Kotha C, Dillard JP.

Appl Environ Microbiol. 2012 May;78(9):3068-78. doi: 10.1128/AEM.07871-11. Epub 2012 Feb 10.


XerCD-mediated site-specific recombination leads to loss of the 57-kilobase gonococcal genetic island.

Domínguez NM, Hackett KT, Dillard JP.

J Bacteriol. 2011 Jan;193(2):377-88. doi: 10.1128/JB.00948-10. Epub 2010 Nov 12.


Increased expression of the type IV secretion system in piliated Neisseria gonorrhoeae variants.

Salgado-Pabón W, Du Y, Hackett KT, Lyons KM, Arvidson CG, Dillard JP.

J Bacteriol. 2010 Apr;192(7):1912-20. doi: 10.1128/JB.01357-09. Epub 2010 Feb 5.


Neisseria gonorrhoeae uses two lytic transglycosylases to produce cytotoxic peptidoglycan monomers.

Cloud-Hansen KA, Hackett KT, Garcia DL, Dillard JP.

J Bacteriol. 2008 Sep;190(17):5989-94. doi: 10.1128/JB.00506-08. Epub 2008 Jun 20.


Characterization of the role of LtgB, a putative lytic transglycosylase in Neisseria gonorrhoeae.

Kohler PL, Cloud KA, Hackett KT, Beck ET, Dillard JP.

Microbiology. 2005 Sep;151(Pt 9):3081-8.


Neisseria gonorrhoeae secretes chromosomal DNA via a novel type IV secretion system.

Hamilton HL, Domínguez NM, Schwartz KJ, Hackett KT, Dillard JP.

Mol Microbiol. 2005 Mar;55(6):1704-21.

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