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Items: 1 to 50 of 100

1.

Prognostic role of body composition parameters in gastric/gastroesophageal junction cancer patients from the EXPAND trial.

Hacker UT, Hasenclever D, Linder N, Stocker G, Chung HC, Kang YK, Moehler M, Busse H, Lordick F.

J Cachexia Sarcopenia Muscle. 2019 Aug 28. doi: 10.1002/jcsm.12484. [Epub ahead of print]

2.

Capsid Engineering Overcomes Barriers Toward Adeno-Associated Virus Vector-Mediated Transduction of Endothelial Cells.

Zhang L, Rossi A, Lange L, Meumann N, Koitzsch U, Christie K, Nesbit MA, Moore CBT, Hacker UT, Morgan M, Hoffmann D, Zengel J, Carette JE, Schambach A, Salvetti A, Odenthal M, Büning H.

Hum Gene Ther. 2019 Oct;30(10):1284-1296. doi: 10.1089/hum.2019.027.

PMID:
31407607
3.

Immunotherapy: New Options in Gastrointestinal Cancers?

Tannapfel A, Reinacher-Schick A, Hacker U, Lorenzen S, Möhler M, Vogel A.

Visc Med. 2019 Mar;35(1):47-51. doi: 10.1159/000497293. Epub 2019 Feb 14. No abstract available.

PMID:
31312650
4.

High prevalence of severe hypovitaminosis D in patients with advanced gastric cancer treated with first-line chemotherapy with or without anti-EGFR-directed monoclonal antibody (EXPAND trial) showing no prognostic impact.

Obermannova R, Valik D, Hasenclever D, Zdrazilova-Dubska L, Hacker U, Demlova R, Selingerova I, Lordick F.

Eur J Cancer. 2019 Jul;116:107-113. doi: 10.1016/j.ejca.2019.05.011. Epub 2019 Jun 10.

PMID:
31195354
5.

Characterization of a Novel Third-Generation Anti-CD24-CAR against Ovarian Cancer.

Klapdor R, Wang S, Morgan M, Dörk T, Hacker U, Hillemanns P, Büning H, Schambach A.

Int J Mol Sci. 2019 Feb 3;20(3). pii: E660. doi: 10.3390/ijms20030660.

6.

Randomised phase II trial to investigate catumaxomab (anti-EpCAM × anti-CD3) for treatment of peritoneal carcinomatosis in patients with gastric cancer.

Knödler M, Körfer J, Kunzmann V, Trojan J, Daum S, Schenk M, Kullmann F, Schroll S, Behringer D, Stahl M, Al-Batran SE, Hacker U, Ibach S, Lindhofer H, Lordick F.

Br J Cancer. 2018 Aug;119(3):296-302. doi: 10.1038/s41416-018-0150-6. Epub 2018 Jul 10.

7.

Clinical consequences of chemotherapy dose reduction in obese patients with stage III colon cancer: A retrospective analysis from the PETACC 3 study.

Stocker G, Hacker UT, Fiteni F, John Mahachie J, Roth AD, Van Cutsem E, Peeters M, Lordick F, Mauer M.

Eur J Cancer. 2018 Aug;99:49-57. doi: 10.1016/j.ejca.2018.05.004. Epub 2018 Jun 15.

PMID:
29906734
8.

Direct comparison between in vivo and in vitro microsized particle phagocytosis assays in Drosophila melanogaster.

Adolfsson K, Abariute L, Dabkowska AP, Schneider M, Häcker U, Prinz CN.

Toxicol In Vitro. 2018 Feb;46:213-218. doi: 10.1016/j.tiv.2017.10.014. Epub 2017 Oct 9.

PMID:
29024778
9.

Improved Killing of Ovarian Cancer Stem Cells by Combining a Novel Chimeric Antigen Receptor-Based Immunotherapy and Chemotherapy.

Klapdor R, Wang S, Hacker U, Büning H, Morgan M, Dörk T, Hillemanns P, Schambach A.

Hum Gene Ther. 2017 Oct;28(10):886-896. doi: 10.1089/hum.2017.168. Epub 2017 Aug 24.

PMID:
28836469
10.

An unusual hypoechoic solid mass in the pancreatic head.

Blank V, Schierle K, Hacker U, Herta T, Vucinic V, Hoffmeister A, Mössner J, Jansen-Winkeln B, Keim V, Karlas T.

Z Gastroenterol. 2017 Apr;55(4):375-378. doi: 10.1055/s-0043-100023. Epub 2017 Apr 20.

PMID:
28427108
11.

Autophagy determines efficiency of liver-directed gene therapy with adeno-associated viral vectors.

Hösel M, Huber A, Bohlen S, Lucifora J, Ronzitti G, Puzzo F, Boisgerault F, Hacker UT, Kwanten WJ, Klöting N, Blüher M, Gluschko A, Schramm M, Utermöhlen O, Bloch W, Mingozzi F, Krut O, Büning H.

Hepatology. 2017 Jul;66(1):252-265. doi: 10.1002/hep.29176. Epub 2017 May 29.

12.

A combination of low-dose bevacizumab and imatinib enhances vascular normalisation without inducing extracellular matrix deposition.

Schiffmann LM, Brunold M, Liwschitz M, Goede V, Loges S, Wroblewski M, Quaas A, Alakus H, Stippel D, Bruns CJ, Hallek M, Kashkar H, Hacker UT, Coutelle O.

Br J Cancer. 2017 Feb 28;116(5):600-608. doi: 10.1038/bjc.2017.13. Epub 2017 Jan 31.

13.

Adeno-Associated Viral Vectors Transduce Mature Human Adipocytes in Three-Dimensional Slice Cultures.

Kallendrusch S, Schopow N, Stadler SC, Büning H, Hacker UT.

Hum Gene Ther Methods. 2016 Oct;27(5):171-173.

PMID:
27650213
14.

Treatment with Antiangiogenic Drugs in Multiple Lines in Patients with Metastatic Colorectal Cancer: Meta-Analysis of Randomized Trials.

Hofheinz RD, Ronellenfitsch U, Kubicka S, Falcone A, Burkholder I, Hacker UT.

Gastroenterol Res Pract. 2016;2016:9189483. doi: 10.1155/2016/9189483. Epub 2016 Aug 30. Review.

15.

Inhibitors of Angiogenesis.

Büning H, Hacker UT.

Adv Exp Med Biol. 2016;917:261-85. doi: 10.1007/978-3-319-32805-8_12. Review.

PMID:
27236560
16.

Evaluation of Angiopoietin-2 as a biomarker in gastric cancer: results from the randomised phase III AVAGAST trial.

Hacker UT, Escalona-Espinosa L, Consalvo N, Goede V, Schiffmann L, Scherer SJ, Hedge P, Van Cutsem E, Coutelle O, Büning H.

Br J Cancer. 2016 Apr 12;114(8):855-62. doi: 10.1038/bjc.2016.30. Epub 2016 Mar 31.

17.

Cholesterol metabolism and breast cancer.

Stadler SC, Hacker U, Burkhardt R.

Curr Opin Lipidol. 2016 Apr;27(2):200-1. doi: 10.1097/MOL.0000000000000285. No abstract available.

PMID:
26959708
18.

[Weight loss in cancer patients].

Lordick F, Hacker U.

Dtsch Med Wochenschr. 2016 Feb;141(4):247-52. doi: 10.1055/s-0041-107943. Epub 2016 Feb 17. German.

PMID:
26886037
19.

[Current standards in the treatment of gastric cancer].

Hacker U, Lordick F.

Dtsch Med Wochenschr. 2015 Sep;140(19):1417. doi: 10.1055/s-0041-106868. Epub 2015 Sep 24. German. No abstract available.

PMID:
26402172
20.

Engineering the AAV capsid to optimize vector-host-interactions.

Büning H, Huber A, Zhang L, Meumann N, Hacker U.

Curr Opin Pharmacol. 2015 Oct;24:94-104. doi: 10.1016/j.coph.2015.08.002. Epub 2015 Aug 25. Review.

PMID:
26302254
21.

How to Create Evidence for the Integration of Local and Locoregional Treatments in Future Oncological Treatment Concepts?

Lordick F, Ricke J, Mohnike K, Hacker U.

Viszeralmedizin. 2014 Aug;30(4):261-8. doi: 10.1159/000365313. Review.

22.

[Current standards in the treatment of gastric cancer].

Hacker U, Lordick F.

Dtsch Med Wochenschr. 2015 Aug;140(16):1202-5. doi: 10.1055/s-0041-102756. Epub 2015 Aug 11. Review. German. Erratum in: Dtsch Med Wochenschr. 2015 Sep;140(19):1417.

PMID:
26261926
23.

Dual targeting of Angiopoetin-2 and VEGF potentiates effective vascular normalisation without inducing empty basement membrane sleeves in xenograft tumours.

Coutelle O, Schiffmann LM, Liwschitz M, Brunold M, Goede V, Hallek M, Kashkar H, Hacker UT.

Br J Cancer. 2015 Feb 3;112(3):495-503. doi: 10.1038/bjc.2014.629. Epub 2015 Jan 6.

24.

Prognostic serum cytokines in classical Hodgkin lymphoma--letter.

Coutelle O, Büning H, Plütschow A, Fuchs M, Escalona-Espinosa L, Engert A, Hacker U.

Clin Cancer Res. 2014 Dec 15;20(24):6633. doi: 10.1158/1078-0432.CCR-14-1735. No abstract available.

25.

Phase I clinical study of the toll-like receptor 9 agonist MGN1703 in patients with metastatic solid tumours.

Weihrauch MR, Richly H, von Bergwelt-Baildon MS, Becker HJ, Schmidt M, Hacker UT, Shimabukuro-Vornhagen A, Holtick U, Nokay B, Schroff M, Wittig B, Scheulen ME.

Eur J Cancer. 2015 Jan;51(2):146-56. doi: 10.1016/j.ejca.2014.11.002. Epub 2014 Dec 2.

PMID:
25480557
26.

Embelin inhibits endothelial mitochondrial respiration and impairs neoangiogenesis during tumor growth and wound healing.

Coutelle O, Hornig-Do HT, Witt A, Andree M, Schiffmann LM, Piekarek M, Brinkmann K, Seeger JM, Liwschitz M, Miwa S, Hallek M, Krönke M, Trifunovic A, Eming SA, Wiesner RJ, Hacker UT, Kashkar H.

EMBO Mol Med. 2014 May;6(5):624-39. doi: 10.1002/emmm.201303016.

27.

Tropism-modified AAV vectors overcome barriers to successful cutaneous therapy.

Sallach J, Di Pasquale G, Larcher F, Niehoff N, Rübsam M, Huber A, Chiorini J, Almarza D, Eming SA, Ulus H, Nishimura S, Hacker UT, Hallek M, Niessen CM, Büning H.

Mol Ther. 2014 May;22(5):929-39. doi: 10.1038/mt.2014.14. Epub 2014 Jan 28.

28.

[Neoadjuvant chemotherapy or primary surgery for colorectal liver metastases. Pro adjuvant chemotherapy].

Lordick F, Knödler M, Hacker U, Bartels M.

Chirurg. 2014 Jan;85(1):11-6. doi: 10.1007/s00104-013-2564-2. German.

PMID:
24292192
29.

Phase I/II trial of capecitabine and oxaliplatin in combination with bevacizumab and imatinib in patients with metastatic colorectal cancer: AIO KRK 0205.

Hoehler T, von Wichert G, Schimanski C, Kanzler S, Moehler MH, Hinke A, Seufferlein T, Siebler J, Hochhaus A, Arnold D, Hallek M, Hofheinz R, Hacker UT.

Br J Cancer. 2013 Sep 17;109(6):1408-13. doi: 10.1038/bjc.2013.409. Epub 2013 Aug 20.

30.

Ingestion of gallium phosphide nanowires has no adverse effect on Drosophila tissue function.

Adolfsson K, Schneider M, Hammarin G, Häcker U, Prinz CN.

Nanotechnology. 2013 Jul 19;24(28):285101. doi: 10.1088/0957-4484/24/28/285101. Epub 2013 Jun 20.

PMID:
23787695
31.

Ubiquitin C-terminal hydrolase-L1 potentiates cancer chemosensitivity by stabilizing NOXA.

Brinkmann K, Zigrino P, Witt A, Schell M, Ackermann L, Broxtermann P, Schüll S, Andree M, Coutelle O, Yazdanpanah B, Seeger JM, Klubertz D, Drebber U, Hacker UT, Krönke M, Mauch C, Hoppe T, Kashkar H.

Cell Rep. 2013 Mar 28;3(3):881-91. doi: 10.1016/j.celrep.2013.02.014. Epub 2013 Mar 14.

32.

Regorafenib in combination with FOLFOX or FOLFIRI as first- or second-line treatment of colorectal cancer: results of a multicenter, phase Ib study.

Schultheis B, Folprecht G, Kuhlmann J, Ehrenberg R, Hacker UT, Köhne CH, Kornacker M, Boix O, Lettieri J, Krauss J, Fischer R, Hamann S, Strumberg D, Mross KB.

Ann Oncol. 2013 Jun;24(6):1560-7. doi: 10.1093/annonc/mdt056. Epub 2013 Mar 13.

33.

Optimizing the adeno-associated viral vector system: a brief summary.

Hacker U, Büning H.

Ther Deliv. 2011 Aug;2(8):967-70.

PMID:
22826865
34.

Expression of platelet-derived growth factor-C and insulin-like growth factor I in hepatic stellate cells is inhibited by miR-29.

Kwiecinski M, Elfimova N, Noetel A, Töx U, Steffen HM, Hacker U, Nischt R, Dienes HP, Odenthal M.

Lab Invest. 2012 Jul;92(7):978-87. doi: 10.1038/labinvest.2012.70. Epub 2012 May 7.

35.

Analysis of Tie2-expressing monocytes (TEM) in patients with colorectal cancer.

Goede V, Coutelle O, Shimabukuro-Vornhagen A, Holtick U, Neuneier J, Koslowsky TC, Weihrauch MR, von Bergwelt-Baildon M, Hacker UT.

Cancer Invest. 2012 Mar;30(3):225-30. doi: 10.3109/07357907.2011.636114. Epub 2011 Dec 15.

PMID:
22171993
36.

DRhoGEF2 regulates cellular tension and cell pulsations in the Amnioserosa during Drosophila dorsal closure.

Azevedo D, Antunes M, Prag S, Ma X, Hacker U, Brodland GW, Hutson MS, Solon J, Jacinto A.

PLoS One. 2011;6(9):e23964. doi: 10.1371/journal.pone.0023964. Epub 2011 Sep 16.

37.
38.

[Recent results of research on cancer of the colon, gastric cancer, sarcoma and bronchial carcinoma].

Hacker UT, Wolf J, Wendtner CM.

Dtsch Med Wochenschr. 2011 Feb;136(5):179-81. doi: 10.1055/s-0031-1272504. Epub 2011 Jan 26. Review. German.

PMID:
21271476
39.

[Multimodality therapy of colorectal cancer].

Hacker U, Hallek M, Kubicka S.

Internist (Berl). 2010 Nov;51(11):1366-73. doi: 10.1007/s00108-010-2671-9. Review. German.

PMID:
20967408
40.

Identification of serum angiopoietin-2 as a biomarker for clinical outcome of colorectal cancer patients treated with bevacizumab-containing therapy.

Goede V, Coutelle O, Neuneier J, Reinacher-Schick A, Schnell R, Koslowsky TC, Weihrauch MR, Cremer B, Kashkar H, Odenthal M, Augustin HG, Schmiegel W, Hallek M, Hacker UT.

Br J Cancer. 2010 Oct 26;103(9):1407-14. doi: 10.1038/sj.bjc.6605925. Epub 2010 Oct 5.

41.

Hedgehog, but not Odd skipped, induces segmental grooves in the Drosophila epidermis.

Mulinari S, Häcker U.

Development. 2009 Dec;136(23):3875-80. doi: 10.1242/dev.040089.

42.

[Adjuvant therapy of colon carcinoma].

Trarbach T, Kubicka S, Hacker U, Ridwelski K, Reinacher-Schick A.

Onkologie. 2008;31 Suppl 5:19-23. doi: 10.1159/000163072. Epub 2008 Nov 14. Review. German.

PMID:
19033700
43.

[Colorectal carcinoma--primary treatment in case of advanced metastization].

Arnold D, Siewczynski R, Kubicka S, Hacker U, Schmoll HJ.

Onkologie. 2008;31 Suppl 5:3-8. doi: 10.1159/000163066. Epub 2008 Nov 21. Review. German. Erratum in: Onkologie. 2009 Jun;32(6):336.

PMID:
19033697
44.

Complete remission in a colon cancer patient with a large, irresectable liver metastasis after XELOX/cetuximab/bevacizumab treatment.

Weihrauch MR, Stippel D, Fries JW, Arnold D, Bovenschulte H, Coutelle O, Hacker U.

Onkologie. 2008 Sep;31(8-9):464-7. doi: 10.1159/000142388. Epub 2008 Aug 12.

PMID:
18787354
45.

DRhoGEF2 and diaphanous regulate contractile force during segmental groove morphogenesis in the Drosophila embryo.

Mulinari S, Barmchi MP, Häcker U.

Mol Biol Cell. 2008 May;19(5):1883-92. doi: 10.1091/mbc.E07-12-1230. Epub 2008 Feb 20.

46.

Expression and regulation of Spätzle-processing enzyme in Drosophila.

Mulinari S, Häcker U, Castillejo-López C.

FEBS Lett. 2006 Oct 2;580(22):5406-10. Epub 2006 Sep 18.

47.

The serine protease Sp7 is expressed in blood cells and regulates the melanization reaction in Drosophila.

Castillejo-López C, Häcker U.

Biochem Biophys Res Commun. 2005 Dec 16;338(2):1075-82. Epub 2005 Oct 21.

PMID:
16256951
48.

Heparan sulphate proteoglycans: the sweet side of development.

Häcker U, Nybakken K, Perrimon N.

Nat Rev Mol Cell Biol. 2005 Jul;6(7):530-41. Review.

PMID:
16072037
49.

Gene transfer preferentially selects MHC class I positive tumour cells and enhances tumour immunogenicity.

Hacker UT, Schildhauer I, Barroso MC, Kofler DM, Gerner FM, Mysliwietz J, Buening H, Hallek M, King SB.

Cancer Immunol Immunother. 2006 May;55(5):547-57. Epub 2005 Jul 26.

PMID:
16044254
50.

Adeno-associated virus serotypes 1 to 5 mediated tumor cell directed gene transfer and improvement of transduction efficiency.

Hacker UT, Wingenfeld L, Kofler DM, Schuhmann NK, Lutz S, Herold T, King SB, Gerner FM, Perabo L, Rabinowitz J, McCarty DM, Samulski RJ, Hallek M, Büning H.

J Gene Med. 2005 Nov;7(11):1429-38.

PMID:
15945124

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