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Items: 1 to 50 of 142

1.

Chromatin three-dimensional interactions mediate genetic effects on gene expression.

Delaneau O, Zazhytska M, Borel C, Giannuzzi G, Rey G, Howald C, Kumar S, Ongen H, Popadin K, Marbach D, Ambrosini G, Bielser D, Hacker D, Romano L, Ribaux P, Wiederkehr M, Falconnet E, Bucher P, Bergmann S, Antonarakis SE, Reymond A, Dermitzakis ET.

Science. 2019 May 3;364(6439). pii: eaat8266. doi: 10.1126/science.aat8266.

PMID:
31048460
2.

BRB-seq: ultra-affordable high-throughput transcriptomics enabled by bulk RNA barcoding and sequencing.

Alpern D, Gardeux V, Russeil J, Mangeat B, Meireles-Filho ACA, Breysse R, Hacker D, Deplancke B.

Genome Biol. 2019 Apr 19;20(1):71. doi: 10.1186/s13059-019-1671-x.

3.

Cognitive Behavioral Therapy Plus Standard Care Versus Standard Care Plus Other Psychosocial Treatments for People With Schizophrenia.

Jones C, Hacker D, Cormac I, Meaden A, Irving CB, Xia J, Zhao S, Shi C, Chen J.

Schizophr Bull. 2019 Mar 7;45(2):284-286. doi: 10.1093/schbul/sby188. No abstract available.

PMID:
30843049
4.

Cognitive behavioural therapy plus standard care versus standard care for people with schizophrenia.

Jones C, Hacker D, Xia J, Meaden A, Irving CB, Zhao S, Chen J, Shi C.

Cochrane Database Syst Rev. 2018 Dec 20;12:CD007964. doi: 10.1002/14651858.CD007964.pub2.

PMID:
30572373
5.

Cognitive behavioural therapy plus standard care versus standard care plus other psychosocial treatments for people with schizophrenia.

Jones C, Hacker D, Meaden A, Cormac I, Irving CB, Xia J, Zhao S, Shi C, Chen J.

Cochrane Database Syst Rev. 2018 Nov 15;11:CD008712. doi: 10.1002/14651858.CD008712.pub3.

PMID:
30480760
6.

CHO and HEK293 Cultivation and Transfection in Single-Use Orbitally Shaken Bioreactors.

Hacker DL, Durrer L, Quinche S.

Methods Mol Biol. 2018;1850:123-131. doi: 10.1007/978-1-4939-8730-6_9.

PMID:
30242684
7.

Improved process conditions for increasing expression of MHC class II protein from a stable Drosophila S2 cell line.

Shen X, Dojcinovic D, Baldi L, Hacker DL, Luescher IF, Wurm FM.

Biotechnol Lett. 2018 Jan;40(1):85-92. doi: 10.1007/s10529-017-2440-0. Epub 2017 Oct 9.

PMID:
28993910
8.

Genetic incorporation of 4-fluorohistidine into peptides enables selective affinity purification.

Ring CM, Iqbal ES, Hacker DE, Hartman MCT, Cropp TA.

Org Biomol Chem. 2017 May 31;15(21):4536-4539. doi: 10.1039/c7ob00844a.

9.

Large-Scale Transient Transfection of Chinese Hamster Ovary Cells in Suspension.

Rajendra Y, Balasubramanian S, Hacker DL.

Methods Mol Biol. 2017;1603:45-55. doi: 10.1007/978-1-4939-6972-2_3.

PMID:
28493122
10.

Expression proteomics study to determine metallodrug targets and optimal drug combinations.

Lee RFS, Chernobrovkin A, Rutishauser D, Allardyce CS, Hacker D, Johnsson K, Zubarev RA, Dyson PJ.

Sci Rep. 2017 May 8;7(1):1590. doi: 10.1038/s41598-017-01643-1.

11.

The Development and Psychometric Evaluation of a Supplementary Index Score of the Neuropsychological Assessment Battery Screening Module that is Sensitive to Traumatic Brain Injury.

Hacker D, Jones CA, Clowes Z, Belli A, Su Z, Sitaraman M, Davies D, Taylor R, Flahive E, Travis C, O'Neil N, Pettigrew Y.

Arch Clin Neuropsychol. 2017 Mar 1;32(2):215-227. doi: 10.1093/arclin/acw087.

PMID:
28365746
12.

Highly Constrained Bicyclic Scaffolds for the Discovery of Protease-Stable Peptides via mRNA Display.

Hacker DE, Hoinka J, Iqbal ES, Przytycka TM, Hartman MC.

ACS Chem Biol. 2017 Mar 17;12(3):795-804. doi: 10.1021/acschembio.6b01006. Epub 2017 Feb 1.

13.

Studies on fluid dynamics of the flow field and gas transfer in orbitally shaken tubes.

Zhu LK, Song BY, Wang ZL, Monteil DT, Shen X, Hacker DL, De Jesus M, Wurm FM.

Biotechnol Prog. 2017 Jan;33(1):192-200. doi: 10.1002/btpr.2375. Epub 2016 Oct 31.

PMID:
27690196
14.

Individual differences in the impact of vicarious racism: African American students react to the George Zimmerman trial.

Mason TB, Maduro RS, Derlega VJ, Hacker DS, Winstead BA, Haywood JE.

Cultur Divers Ethnic Minor Psychol. 2017 Apr;23(2):174-184. doi: 10.1037/cdp0000099. Epub 2016 Oct 13.

PMID:
27736105
15.

A comparison of orbitally-shaken and stirred-tank bioreactors: pH modulation and bioreactor type affect CHO cell growth and protein glycosylation.

Monteil DT, Juvet V, Paz J, Moniatte M, Baldi L, Hacker DL, Wurm FM.

Biotechnol Prog. 2016 Sep;32(5):1174-1180. doi: 10.1002/btpr.2328. Epub 2016 Aug 11.

PMID:
27453130
16.

Multigene expression in stable CHO cell pools generated with the piggyBac transposon system.

Balasubramanian S, Wurm FM, Hacker DL.

Biotechnol Prog. 2016 Sep;32(5):1308-1317. doi: 10.1002/btpr.2319. Epub 2016 Jul 13.

PMID:
27302570
17.

Presumptive keratoglobus in a great horned owl (Bubo virginianus).

Lau RK, Moresco A, Woods SJ, Reilly CM, Hawkins MG, Murphy CJ, Hollingsworth SR, Hacker D, Freeman KS.

Vet Ophthalmol. 2017 Nov;20(6):560-567. doi: 10.1111/vop.12413. Epub 2016 Jul 31.

PMID:
27477943
18.

Recombinant protein production from stable mammalian cell lines and pools.

Hacker DL, Balasubramanian S.

Curr Opin Struct Biol. 2016 Jun;38:129-36. doi: 10.1016/j.sbi.2016.06.005. Epub 2016 Jun 17. Review.

PMID:
27322762
19.

Disposable orbitally shaken TubeSpin bioreactor 600 for Sf9 cell cultivation in suspension.

Monteil DT, Shen X, Tontodonati G, Baldi L, Hacker DL, Wurm FM.

Anal Biochem. 2016 Jul 15;505:26-8. doi: 10.1016/j.ab.2016.04.009. Epub 2016 Apr 27.

PMID:
27130502
20.

Comparison of three transposons for the generation of highly productive recombinant CHO cell pools and cell lines.

Balasubramanian S, Rajendra Y, Baldi L, Hacker DL, Wurm FM.

Biotechnol Bioeng. 2016 Jun;113(6):1234-43. doi: 10.1002/bit.25888. Epub 2015 Dec 9.

PMID:
26616356
21.

A simple plasmid-based transient gene expression method using High Five cells.

Shen X, Pitol AK, Bachmann V, Hacker DL, Baldi L, Wurm FM.

J Biotechnol. 2015 Dec 20;216:67-75. doi: 10.1016/j.jbiotec.2015.10.007. Epub 2015 Oct 23.

PMID:
26476358
22.

Population Variation and Genetic Control of Modular Chromatin Architecture in Humans.

Waszak SM, Delaneau O, Gschwind AR, Kilpinen H, Raghav SK, Witwicki RM, Orioli A, Wiederkehr M, Panousis NI, Yurovsky A, Romano-Palumbo L, Planchon A, Bielser D, Padioleau I, Udin G, Thurnheer S, Hacker D, Hernandez N, Reymond A, Deplancke B, Dermitzakis ET.

Cell. 2015 Aug 27;162(5):1039-50. doi: 10.1016/j.cell.2015.08.001. Epub 2015 Aug 20.

23.

Enhanced plasmid DNA utilization in transiently transfected CHO-DG44 cells in the presence of polar solvents.

Rajendra Y, Balasubramanian S, Kiseljak D, Baldi L, Wurm FM, Hacker DL.

Biotechnol Prog. 2015 Nov-Dec;31(6):1571-8. doi: 10.1002/btpr.2152. Epub 2015 Aug 25.

PMID:
26260195
24.

Production of active glycosylation-deficient γ-secretase complex for crystallization studies.

López AR, Dimitrov M, Gerber H, Braman V, Hacker DL, Wurm FM, Fraering PC.

Biotechnol Bioeng. 2015 Dec;112(12):2516-26. doi: 10.1002/bit.25675. Epub 2015 Jul 14.

PMID:
26059427
25.

Rapid recombinant protein production from piggyBac transposon-mediated stable CHO cell pools.

Balasubramanian S, Matasci M, Kadlecova Z, Baldi L, Hacker DL, Wurm FM.

J Biotechnol. 2015 Apr 20;200:61-9. doi: 10.1016/j.jbiotec.2015.03.001. Epub 2015 Mar 7.

PMID:
25758242
26.

Transcriptional and post-transcriptional limitations of high-yielding, PEI-mediated transient transfection with CHO and HEK-293E cells.

Rajendra Y, Kiseljak D, Baldi L, Wurm FM, Hacker DL.

Biotechnol Prog. 2015 Mar-Apr;31(2):541-9. doi: 10.1002/btpr.2064. Epub 2015 Feb 26.

PMID:
25683738
27.

Peptide library approach to uncover phosphomimetic inhibitors of the BRCA1 C-terminal domain.

White ER, Sun L, Ma Z, Beckta JM, Danzig BA, Hacker DE, Huie M, Williams DC, Edwards RA, Valerie K, Glover JN, Hartman MC.

ACS Chem Biol. 2015 May 15;10(5):1198-208. doi: 10.1021/cb500757u. Epub 2015 Feb 5.

28.

Peptide and peptide library cyclization via bromomethylbenzene derivatives.

Hacker DE, Almohaini M, Anbazhagan A, Ma Z, Hartman MC.

Methods Mol Biol. 2015;1248:105-17. doi: 10.1007/978-1-4939-2020-4_8.

PMID:
25616329
29.

Virus-free transient protein production in Sf9 cells.

Shen X, Hacker DL, Baldi L, Wurm FM.

J Biotechnol. 2014 Feb 10;171:61-70. doi: 10.1016/j.jbiotec.2013.11.018. Epub 2013 Dec 11.

PMID:
24333123
30.

Coordinated effects of sequence variation on DNA binding, chromatin structure, and transcription.

Kilpinen H, Waszak SM, Gschwind AR, Raghav SK, Witwicki RM, Orioli A, Migliavacca E, Wiederkehr M, Gutierrez-Arcelus M, Panousis NI, Yurovsky A, Lappalainen T, Romano-Palumbo L, Planchon A, Bielser D, Bryois J, Padioleau I, Udin G, Thurnheer S, Hacker D, Core LJ, Lis JT, Hernandez N, Reymond A, Deplancke B, Dermitzakis ET.

Science. 2013 Nov 8;342(6159):744-7. doi: 10.1126/science.1242463. Epub 2013 Oct 17.

31.

Polyethyleneimine-based transient gene expression processes for suspension-adapted HEK-293E and CHO-DG44 cells.

Hacker DL, Kiseljak D, Rajendra Y, Thurnheer S, Baldi L, Wurm FM.

Protein Expr Purif. 2013 Nov;92(1):67-76. doi: 10.1016/j.pep.2013.09.001. Epub 2013 Sep 8.

PMID:
24021764
32.

DNA delivery with hyperbranched polylysine: a comparative study with linear and dendritic polylysine.

Kadlecova Z, Rajendra Y, Matasci M, Baldi L, Hacker DL, Wurm FM, Klok HA.

J Control Release. 2013 Aug 10;169(3):276-88. doi: 10.1016/j.jconrel.2013.01.019. Epub 2013 Feb 1.

PMID:
23379996
33.

Highly efficient production of the Alzheimer's γ-secretase integral membrane protease complex by a multi-gene stable integration approach.

Alattia JR, Matasci M, Dimitrov M, Aeschbach L, Balasubramanian S, Hacker DL, Wurm FM, Fraering PC.

Biotechnol Bioeng. 2013 Jul;110(7):1995-2005. doi: 10.1002/bit.24851. Epub 2013 Feb 15.

PMID:
23359429
34.

Measuring adverse events and levels of harm in pediatric inpatients with the Global Trigger Tool.

Kirkendall ES, Kloppenborg E, Papp J, White D, Frese C, Hacker D, Schoettker PJ, Muething S, Kotagal U.

Pediatrics. 2012 Nov;130(5):e1206-14. doi: 10.1542/peds.2012-0179. Epub 2012 Oct 8.

PMID:
23045558
35.

Cognitive behavior therapy versus other psychosocial treatments for schizophrenia.

Jones C, Hacker D, Cormac I, Meaden A, Irving CB.

Schizophr Bull. 2012 Sep;38(5):908-10. doi: 10.1093/schbul/sbs090. Review. No abstract available.

36.

A NanoDrop-based method for rapid determination of viability decline in suspension cultures of animal cells.

Michel PO, Degen C, Hubert M, Baldi L, Hacker DL, Wurm FM.

Anal Biochem. 2012 Nov 15;430(2):138-40. doi: 10.1016/j.ab.2012.08.028. Epub 2012 Sep 6.

PMID:
22960013
37.

Comparative study on the in vitro cytotoxicity of linear, dendritic, and hyperbranched polylysine analogues.

Kadlecova Z, Baldi L, Hacker D, Wurm FM, Klok HA.

Biomacromolecules. 2012 Oct 8;13(10):3127-37. doi: 10.1021/bm300930j. Epub 2012 Sep 11.

PMID:
22931162
38.

Calibration research: where do we go from here?

Bol L, Hacker DJ.

Front Psychol. 2012 Jul 9;3:229. doi: 10.3389/fpsyg.2012.00229. eCollection 2012.

39.

Chemical macrocyclization of peptides fused to antibody Fc fragments.

Angelini A, Diderich P, Morales-Sanfrutos J, Thurnheer S, Hacker D, Menin L, Heinis C.

Bioconjug Chem. 2012 Sep 19;23(9):1856-63. Epub 2012 Aug 10.

PMID:
22812498
40.

Developing a measurement of engagement: the Residential Rehabilitation Engagement Scale for psychosis.

Meaden A, Hacker D, de Villiers A, Carbourne J, Paget A.

J Ment Health. 2012 Apr;21(2):182-91. doi: 10.3109/09638237.2012.664301.

PMID:
22559829
41.

Lyin' eyes: ocular-motor measures of reading reveal deception.

Cook AE, Hacker DJ, Webb AK, Osher D, Kristjansson SD, Woltz DJ, Kircher JC.

J Exp Psychol Appl. 2012 Sep;18(3):301-13. doi: 10.1037/a0028307. Epub 2012 Apr 30.

42.

Cognitive behaviour therapy versus other psychosocial treatments for schizophrenia.

Jones C, Hacker D, Cormac I, Meaden A, Irving CB.

Cochrane Database Syst Rev. 2012 Apr 18;(4):CD008712. doi: 10.1002/14651858.CD008712.pub2. Review. Update in: Cochrane Database Syst Rev. 2018 Nov 15;11:CD008712.

43.

Hyperbranched polylysine: a versatile, biodegradable transfection agent for the production of recombinant proteins by transient gene expression and the transfection of primary cells.

Kadlecova Z, Rajendra Y, Matasci M, Hacker D, Baldi L, Wurm FM, Klok HA.

Macromol Biosci. 2012 Jun;12(6):794-804. doi: 10.1002/mabi.201100519. Epub 2012 Apr 11.

PMID:
22496075
44.

Role of non-specific DNA in reducing coding DNA requirement for transient gene expression with CHO and HEK-293E cells.

Rajendra Y, Kiseljak D, Manoli S, Baldi L, Hacker DL, Wurm FM.

Biotechnol Bioeng. 2012 Sep;109(9):2271-8. doi: 10.1002/bit.24494. Epub 2012 Mar 30.

PMID:
22422519
45.

Poly(ethyleneimine)-mediated large-scale transient gene expression: influence of molecular weight, polydispersity and N-propionyl groups.

Kadlecova Z, Nallet S, Hacker DL, Baldi L, Klok HA, Wurm FM.

Macromol Biosci. 2012 May;12(5):628-36. doi: 10.1002/mabi.201100404. Epub 2012 Mar 13.

PMID:
22411776
46.

Rapid recombinant protein production from pools of transposon-generated CHO cells.

Matasci M, Bachmann V, Baldi L, Hacker DL, De Jesus M, Wurm FM.

BMC Proc. 2011 Nov 22;5 Suppl 8:P34. doi: 10.1186/1753-6561-5-S8-P34. eCollection 2011. No abstract available.

47.

The use of filler DNA for improved transfection and reduced DNA needs in transient gene expression with CHO and HEK cells.

Kiseljak D, Rajendra Y, Manoli SS, Baldi L, Hacker DL, Wurm FM.

BMC Proc. 2011 Nov 22;5 Suppl 8:P33. doi: 10.1186/1753-6561-5-S8-P33. eCollection 2011. No abstract available.

48.

Transposon mediated co-integration and co-expression of transgenes in CHO-DG44 cells.

Balasubramanian S, Matasci M, Baldi L, Hacker DL, Wurm FM.

BMC Proc. 2011 Nov 22;5 Suppl 8:P32. doi: 10.1186/1753-6561-5-S8-P32. eCollection 2011. No abstract available.

49.

CHO cell lines generated by PiggyBac transposition.

Matasci M, Bachmann V, Baldi L, Hacker DL, De Jesus M, Wurm FM.

BMC Proc. 2011 Nov 22;5 Suppl 8:P31. doi: 10.1186/1753-6561-5-S8-P31. eCollection 2011. No abstract available.

50.

Hydrodynamic stress in orbitally shaken bioreactors.

Tissot S, Reclari M, Quinodoz S, Dreyer M, Monteil DT, Baldi L, Hacker DL, Farhat M, Discacciati M, Quarteroni A, Wurm FM.

BMC Proc. 2011 Nov 22;5 Suppl 8:P39. doi: 10.1186/1753-6561-5-S8-P39. eCollection 2011. No abstract available.

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