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Items: 1 to 50 of 105

1.

Vitamin B 12 deficiency and hyperhomocysteinaemia in outpatients with stroke or transient ischaemic attack: a cohort study at an academic medical centre.

Ahmed S, Bogiatzi C, Hackam DG, Rutledge AC, Sposato LA, Khaw A, Mandzia J, Azarpazhoo MR, Hachinski V, Spence JD.

BMJ Open. 2019 Jan 21;9(1):e026564. doi: 10.1136/bmjopen-2018-026564.

2.

Antiplatelet Therapy in Ischemic Stroke and Transient Ischemic Attack.

Hackam DG, Spence JD.

Stroke. 2019 Mar;50(3):773-778. doi: 10.1161/STROKEAHA.118.023954. No abstract available.

PMID:
30626286
3.

Cholesterol Lowering and Prevention of Stroke.

Hackam DG, Hegele RA.

Stroke. 2019 Feb;50(2):537-541. doi: 10.1161/STROKEAHA.118.023167. No abstract available.

PMID:
30602355
4.

Decline in the Severity of Carotid Atherosclerosis and Associated Risk Factors From 2002 to 2014.

Hackam DG, Spence JD.

Stroke. 2018 Nov;49(11):2786-2788. doi: 10.1161/STROKEAHA.118.021445.

PMID:
30355203
5.

Utilization of Vasculoprotective Therapy for Peripheral Artery Disease: A Systematic Review and Meta-analysis.

Hackam DG, Vyas MV.

Am J Med. 2018 Nov;131(11):1332-1339.e3. doi: 10.1016/j.amjmed.2018.07.006. Epub 2018 Jul 26.

PMID:
30056102
6.

Effects of Eplerenone on Resistance to Antihypertensive Medication in Patients with Primary or Secondary Hyperaldosteronism.

Spence JD, Bogiatzi C, Kuk M, Dresser GK, Hackam DG.

J Transl Int Med. 2017 Jun 30;5(2):93-99. doi: 10.1515/jtim-2017-0020. eCollection 2017 Jun.

7.

Physiological Phenotyping for Personalized Therapy of Uncontrolled Hypertension in Africa.

Akintunde A, Nondi J, Gogo K, Jones ESW, Rayner BL, Hackam DG, Spence JD.

Am J Hypertens. 2017 Sep 1;30(9):923-930. doi: 10.1093/ajh/hpx066.

PMID:
28472315
8.

Population-based stroke and dementia incidence trends: Age and sex variations.

Cerasuolo JO, Cipriano LE, Sposato LA, Kapral MK, Fang J, Gill SS, Hackam DG, Hachinski V.

Alzheimers Dement. 2017 Oct;13(10):1081-1088. doi: 10.1016/j.jalz.2017.02.010. Epub 2017 Mar 28.

PMID:
28363085
9.

High Frequency of Variants of Candidate Genes in Black Africans with Low Renin-Resistant Hypertension.

Jones ES, Spence JD, Mcintyre AD, Nondi J, Gogo K, Akintunde A, Hackam DG, Rayner BL.

Am J Hypertens. 2017 May 1;30(5):478-483. doi: 10.1093/ajh/hpw167.

PMID:
28052878
10.

Lost Productivity in Stroke Survivors: An Econometrics Analysis.

Vyas MV, Hackam DG, Silver FL, Laporte A, Kapral MK.

Neuroepidemiology. 2016;47(3-4):164-170. doi: 10.1159/000454730. Epub 2016 Dec 20.

PMID:
27992866
11.

Antiepileptic drugs and hyponatremia in older adults: Two population-based cohort studies.

Gandhi S, McArthur E, Mamdani MM, Hackam DG, McLachlan RS, Weir MA, Burneo JG, Garg AX.

Epilepsia. 2016 Dec;57(12):2067-2079. doi: 10.1111/epi.13593. Epub 2016 Nov 29.

12.

Second-Generation Antidepressants and Hyponatremia Risk: A Population-Based Cohort Study of Older Adults.

Gandhi S, Shariff SZ, Al-Jaishi A, Reiss JP, Mamdani MM, Hackam DG, Li L, McArthur E, Weir MA, Garg AX.

Am J Kidney Dis. 2017 Jan;69(1):87-96. doi: 10.1053/j.ajkd.2016.08.020. Epub 2016 Oct 20.

PMID:
27773479
13.

Prognosis of Asymptomatic Carotid Artery Occlusion: Systematic Review and Meta-Analysis.

Hackam DG.

Stroke. 2016 May;47(5):1253-7. doi: 10.1161/STROKEAHA.116.012760. Epub 2016 Apr 12. Review.

PMID:
27073237
14.

Atypical antipsychotic medications and hyponatremia in older adults: a population-based cohort study.

Gandhi S, McArthur E, Reiss JP, Mamdani MM, Hackam DG, Weir MA, Garg AX.

Can J Kidney Health Dis. 2016 Apr 11;3:21. doi: 10.1186/s40697-016-0111-z. eCollection 2016.

15.

Macrolide antibiotics and the risk of ventricular arrhythmia in older adults.

Trac MH, McArthur E, Jandoc R, Dixon SN, Nash DM, Hackam DG, Garg AX.

CMAJ. 2016 Apr 19;188(7):E120-E129. doi: 10.1503/cmaj.150901. Epub 2016 Feb 22.

16.

Declining Incidence of Stroke and Dementia: Coincidence or Prevention Opportunity?

Sposato LA, Kapral MK, Fang J, Gill SS, Hackam DG, Cipriano LE, Hachinski V.

JAMA Neurol. 2015 Dec;72(12):1529-31. doi: 10.1001/jamaneurol.2015.2816. No abstract available.

PMID:
26658969
17.

Cannabis and stroke: systematic appraisal of case reports.

Hackam DG.

Stroke. 2015 Mar;46(3):852-6. doi: 10.1161/STROKEAHA.115.008680. Review.

PMID:
25700287
18.

β-Blocker dialyzability and mortality in older patients receiving hemodialysis.

Weir MA, Dixon SN, Fleet JL, Roberts MA, Hackam DG, Oliver MJ, Suri RS, Quinn RR, Ozair S, Beyea MM, Kitchlu A, Garg AX.

J Am Soc Nephrol. 2015 Apr;26(4):987-96. doi: 10.1681/ASN.2014040324. Epub 2014 Oct 30.

19.

Secular trends in ischemic stroke subtypes and stroke risk factors.

Bogiatzi C, Hackam DG, McLeod AI, Spence JD.

Stroke. 2014 Nov;45(11):3208-13. doi: 10.1161/STROKEAHA.114.006536. Epub 2014 Sep 11.

PMID:
25213343
20.

Pulmonary abnormalities and carotid atherosclerosis in ex-smokers without airflow limitation.

Pike D, Kirby M, Lindenmaier TJ, Sheikh K, Neron CE, Hackam DG, Spence JD, Fenster A, Paterson NA, Sin DD, Coxson HO, McCormack DG, Parraga G.

COPD. 2015 Feb;12(1):62-70. doi: 10.3109/15412555.2014.908833. Epub 2014 Jun 12.

PMID:
24921977
21.

Management of risk factors among ambulatory patients at high cardiovascular risk in Canada: a follow-up study.

Elbarasi EA, Goodman SG, Yan RT, Tan MK, Hackam DG, Leiter LA, Langer A, Yan AT; Guidelines Oriented Approach in Lipid Lowering (GOALL) Registry and Vascular Protection (VP) Registry Investigators.

Can J Cardiol. 2013 Dec;29(12):1586-92. doi: 10.1016/j.cjca.2013.06.013. Epub 2013 Sep 13.

PMID:
24041994
22.

Threats to validity in the design and conduct of preclinical efficacy studies: a systematic review of guidelines for in vivo animal experiments.

Henderson VC, Kimmelman J, Fergusson D, Grimshaw JM, Hackam DG.

PLoS Med. 2013;10(7):e1001489. doi: 10.1371/journal.pmed.1001489. Epub 2013 Jul 23. Review.

23.

Underrepresentation of peripheral artery disease in modern cardiovascular trials: systematic review and meta-analysis.

Vyas MV, Mrkobrada M, Donner A, Hackam DG.

Int J Cardiol. 2013 Oct 12;168(5):4875-6. doi: 10.1016/j.ijcard.2013.07.050. Epub 2013 Jul 26. Review. No abstract available.

PMID:
23896535
24.

Progression of carotid plaque volume predicts cardiovascular events.

Wannarong T, Parraga G, Buchanan D, Fenster A, House AA, Hackam DG, Spence JD.

Stroke. 2013 Jul;44(7):1859-65. doi: 10.1161/STROKEAHA.113.001461. Epub 2013 Jun 4.

PMID:
23735956
25.
26.

The 2013 Canadian Hypertension Education Program recommendations for blood pressure measurement, diagnosis, assessment of risk, prevention, and treatment of hypertension.

Hackam DG, Quinn RR, Ravani P, Rabi DM, Dasgupta K, Daskalopoulou SS, Khan NA, Herman RJ, Bacon SL, Cloutier L, Dawes M, Rabkin SW, Gilbert RE, Ruzicka M, McKay DW, Campbell TS, Grover S, Honos G, Schiffrin EL, Bolli P, Wilson TW, Feldman RD, Lindsay P, Hill MD, Gelfer M, Burns KD, Vallée M, Prasad GV, Lebel M, McLean D, Arnold JM, Moe GW, Howlett JG, Boulanger JM, Larochelle P, Leiter LA, Jones C, Ogilvie RI, Woo V, Kaczorowski J, Trudeau L, Petrella RJ, Milot A, Stone JA, Drouin D, Lavoie KL, Lamarre-Cliche M, Godwin M, Tremblay G, Hamet P, Fodor G, Carruthers SG, Pylypchuk GB, Burgess E, Lewanczuk R, Dresser GK, Penner SB, Hegele RA, McFarlane PA, Sharma M, Reid DJ, Tobe SW, Poirier L, Padwal RS; Canadian Hypertension Education Program.

Can J Cardiol. 2013 May;29(5):528-42. doi: 10.1016/j.cjca.2013.01.005. Epub 2013 Mar 29.

PMID:
23541660
27.

Risk of acute kidney injury from oral acyclovir: a population-based study.

Lam NN, Weir MA, Yao Z, Blake PG, Beyea MM, Gomes T, Gandhi S, Mamdani M, Wald R, Parikh CR, Hackam DG, Garg AX.

Am J Kidney Dis. 2013 May;61(5):723-9. doi: 10.1053/j.ajkd.2012.12.008. Epub 2013 Jan 10.

PMID:
23312723
28.

Selective serotonin reuptake inhibitors and brain hemorrhage: a meta-analysis.

Hackam DG, Mrkobrada M.

Neurology. 2012 Oct 30;79(18):1862-5. doi: 10.1212/WNL.0b013e318271f848. Epub 2012 Oct 17. Review.

PMID:
23077009
29.

Low sodium versus normal sodium diets in systolic heart failure: systematic review and meta-analysis.

DiNicolantonio JJ, Di Pasquale P, Taylor RS, Hackam DG.

Heart. 2013 Mar 12. doi: 10.1136/heartjnl-2012-302337. Epub 2013 Mar 12. No abstract available. Retraction in: Heart. 2013 Jun;99(11):820.

PMID:
22914535
30.

Shift work and vascular events: systematic review and meta-analysis.

Vyas MV, Garg AX, Iansavichus AV, Costella J, Donner A, Laugsand LE, Janszky I, Mrkobrada M, Parraga G, Hackam DG.

BMJ. 2012 Jul 26;345:e4800. doi: 10.1136/bmj.e4800. Review.

31.

Lifetime risk prediction in cardiovascular prevention: wave of the future?

Gryn SE, Hackam DG.

Can J Cardiol. 2013 Feb;29(2):142-3. doi: 10.1016/j.cjca.2012.05.002. Epub 2012 Jul 7. No abstract available.

PMID:
22771015
32.

Effects of aldosterone on human atherosclerosis: plasma aldosterone and progression of carotid plaque.

de Rita O, Hackam DG, Spence JD.

Can J Cardiol. 2012 Nov-Dec;28(6):706-11. doi: 10.1016/j.cjca.2012.04.014. Epub 2012 Jun 19.

PMID:
22717248
33.

The 2012 Canadian hypertension education program recommendations for the management of hypertension: blood pressure measurement, diagnosis, assessment of risk, and therapy.

Daskalopoulou SS, Khan NA, Quinn RR, Ruzicka M, McKay DW, Hackam DG, Rabkin SW, Rabi DM, Gilbert RE, Padwal RS, Dawes M, Touyz RM, Campbell TS, Cloutier L, Grover S, Honos G, Herman RJ, Schiffrin EL, Bolli P, Wilson T, Feldman RD, Lindsay MP, Hemmelgarn BR, Hill MD, Gelfer M, Burns KD, Vallée M, Prasad GV, Lebel M, McLean D, Arnold JM, Moe GW, Howlett JG, Boulanger JM, Larochelle P, Leiter LA, Jones C, Ogilvie RI, Woo V, Kaczorowski J, Trudeau L, Bacon SL, Petrella RJ, Milot A, Stone JA, Drouin D, Lamarre-Cliché M, Godwin M, Tremblay G, Hamet P, Fodor G, Carruthers SG, Pylypchuk G, Burgess E, Lewanczuk R, Dresser GK, Penner B, Hegele RA, McFarlane PA, Sharma M, Campbell NR, Reid D, Poirier L, Tobe SW; Canadian Hypertension Education Program.

Can J Cardiol. 2012 May;28(3):270-87. doi: 10.1016/j.cjca.2012.02.018. Review.

PMID:
22595447
34.

The relationship of carotid three-dimensional ultrasound vessel wall volume with age and sex: comparison to carotid intima-media thickness.

Buchanan DN, Lindenmaier T, McKay S, Bureau Y, Hackam DG, Fenster A, Parraga G.

Ultrasound Med Biol. 2012 Jul;38(7):1145-53. doi: 10.1016/j.ultrasmedbio.2012.02.013. Epub 2012 May 12.

PMID:
22579542
35.

New fibrate use and acute renal outcomes in elderly adults: a population-based study.

Zhao YY, Weir MA, Manno M, Cordy P, Gomes T, Hackam DG, Juurlink DN, Mamdani M, Moist L, Parikh CR, Paterson JM, Wald R, Yao Z, Garg AX.

Ann Intern Med. 2012 Apr 17;156(8):560-9. doi: 10.7326/0003-4819-156-8-201204170-00003.

PMID:
22508733
36.

Use of angiotensin-converting enzyme inhibitors or angiotensin receptor blockers and cardiovascular outcomes in chronic dialysis patients: a population-based cohort study.

Bajaj RR, Wald R, Hackam DG, Gomes T, Perl J, Juurlink DN, Manno M, Garg AX, Kitchlu A, Mamdani MM, Yan AT.

Arch Intern Med. 2012 Apr 9;172(7):591-3. doi: 10.1001/archinternmed.2012.139. No abstract available. Erratum in: Arch Intern Med. 2012 Jun 25;172(12):908.

PMID:
22493468
37.

Carvedilol: a third-generation β-blocker should be a first-choice β-blocker.

DiNicolantonio JJ, Hackam DG.

Expert Rev Cardiovasc Ther. 2012 Jan;10(1):13-25. doi: 10.1586/erc.11.166. Review.

PMID:
22149523
38.

Statins and intracerebral hemorrhage: collaborative systematic review and meta-analysis.

Hackam DG, Woodward M, Newby LK, Bhatt DL, Shao M, Smith EE, Donner A, Mamdani M, Douketis JD, Arima H, Chalmers J, MacMahon S, Tirschwell DL, Psaty BM, Bushnell CD, Aguilar MI, Capampangan DJ, Werring DJ, De Rango P, Viswanathan A, Danchin N, Cheng CL, Yang YH, Verdel BM, Lai MS, Kennedy J, Uchiyama S, Yamaguchi T, Ikeda Y, Mrkobrada M.

Circulation. 2011 Nov 15;124(20):2233-42. doi: 10.1161/CIRCULATIONAHA.111.055269. Epub 2011 Oct 17. Review.

PMID:
22007076
39.

Statins and intracerebral hemorrhage: a retrospective cohort study.

Hackam DG, Austin PC, Huang A, Juurlink DN, Mamdani MM, Paterson JM, Hachinski V, Li P, Kapral MK.

Arch Neurol. 2012 Jan;69(1):39-45. doi: 10.1001/archneurol.2011.228. Epub 2011 Sep 12.

PMID:
21911657
40.

Beta-blockers and cardiovascular outcomes in dialysis patients: a cohort study in Ontario, Canada.

Kitchlu A, Clemens K, Gomes T, Hackam DG, Juurlink DN, Mamdani M, Manno M, Oliver MJ, Quinn RR, Suri RS, Wald R, Yan AT, Garg AX.

Nephrol Dial Transplant. 2012 Apr;27(4):1591-8. doi: 10.1093/ndt/gfr460. Epub 2011 Aug 26.

PMID:
21873621
41.

The 2011 Canadian Hypertension Education Program recommendations for the management of hypertension: blood pressure measurement, diagnosis, assessment of risk, and therapy.

Rabi DM, Daskalopoulou SS, Padwal RS, Khan NA, Grover SA, Hackam DG, Myers MG, McKay DW, Quinn RR, Hemmelgarn BR, Cloutier L, Bolli P, Hill MD, Wilson T, Penner B, Burgess E, Lamarre-Cliché M, McLean D, Schiffrin EL, Honos G, Mann K, Tremblay G, Milot A, Chockalingam A, Rabkin SW, Dawes M, Touyz RM, Burns KD, Ruzicka M, Campbell NR, Vallée M, Prasad GV, Lebel M, Campbell TS, Lindsay MP, Herman RJ, Larochelle P, Feldman RD, Arnold JM, Moe GW, Howlett JG, Trudeau L, Bacon SL, Petrella RJ, Lewanczuk R, Stone JA, Drouin D, Boulanger JM, Sharma M, Hamet P, Fodor G, Dresser GK, Carruthers SG, Pylypchuk G, Gilbert RE, Leiter LA, Jones C, Ogilvie RI, Woo V, McFarlane PA, Hegele RA, Poirier L, Tobe SW; Canadian Hypertension Education Program.

Can J Cardiol. 2011 Jul-Aug;27(4):415-433.e1-2. doi: 10.1016/j.cjca.2011.03.015. English, French.

PMID:
21801975
42.

Influence of noninvasive cardiovascular imaging in primary prevention: systematic review and meta-analysis of randomized trials.

Hackam DG, Shojania KG, Spence JD, Alter DA, Beanlands RS, Dresser GK, Goela A, Davies AH, Badano LP, Poldermans D, Boersma E, Njike VY.

Arch Intern Med. 2011 Jun 13;171(11):977-82. doi: 10.1001/archinternmed.2011.69. Epub 2011 Mar 14. Review.

PMID:
21403010
43.

Hospital admissions for hyperkalemia with trimethoprim-sulfamethoxazole: a cohort study using health care database codes for 393,039 older women with urinary tract infections.

Lam N, Weir MA, Juurlink DN, Gunraj N, Gomes T, Mamdani M, Hackam DG, Jain AK, Garg AX.

Am J Kidney Dis. 2011 Mar;57(3):521-3. doi: 10.1053/j.ajkd.2010.11.006. Epub 2011 Jan 8. No abstract available.

PMID:
21216514
44.

Validity of administrative database coding for kidney disease: a systematic review.

Vlasschaert ME, Bejaimal SA, Hackam DG, Quinn R, Cuerden MS, Oliver MJ, Iansavichus A, Sultan N, Mills A, Garg AX.

Am J Kidney Dis. 2011 Jan;57(1):29-43. doi: 10.1053/j.ajkd.2010.08.031. Review.

PMID:
21184918
45.

Statins and renovascular disease in the elderly: a population-based cohort study.

Hackam DG, Wu F, Li P, Austin PC, Tobe SW, Mamdani MM, Garg AX.

Eur Heart J. 2011 Mar;32(5):598-610. doi: 10.1093/eurheartj/ehq452. Epub 2010 Dec 14.

46.

Impaired renal function modifies the risk of severe hypoglycaemia among users of insulin but not glyburide: a population-based nested case-control study.

Weir MA, Gomes T, Mamdani M, Juurlink DN, Hackam DG, Mahon JL, Jain AK, Garg AX.

Nephrol Dial Transplant. 2011 Jun;26(6):1888-94. doi: 10.1093/ndt/gfq649. Epub 2010 Oct 25.

PMID:
20974644
47.

Anticoagulant response after dalteparin overdose.

Hasan K, Lazo-Langner A, Acedillo R, Zeller M, Hackam DG.

J Thromb Haemost. 2010 Oct;8(10):2321-3. doi: 10.1111/j.1538-7836.2010.03984.x. No abstract available.

48.

Beta-blockers, trimethoprim-sulfamethoxazole, and the risk of hyperkalemia requiring hospitalization in the elderly: a nested case-control study.

Weir MA, Juurlink DN, Gomes T, Mamdani M, Hackam DG, Jain AK, Garg AX.

Clin J Am Soc Nephrol. 2010 Sep;5(9):1544-51. doi: 10.2215/CJN.01970310. Epub 2010 Jul 1.

49.

The 2010 Canadian Hypertension Education Program recommendations for the management of hypertension: part 2 - therapy.

Hackam DG, Khan NA, Hemmelgarn BR, Rabkin SW, Touyz RM, Campbell NR, Padwal R, Campbell TS, Lindsay MP, Hill MD, Quinn RR, Mahon JL, Herman RJ, Schiffrin EL, Ruzicka M, Larochelle P, Feldman RD, Lebel M, Poirier L, Arnold JM, Moe GW, Howlett JG, Trudeau L, Bacon SL, Petrella RJ, Milot A, Stone JA, Drouin D, Boulanger JM, Sharma M, Hamet P, Fodor G, Dresser GK, Carruthers SG, Pylypchuk G, Burgess ED, Burns KD, Vallée M, Prasad GV, Gilbert RE, Leiter LA, Jones C, Ogilvie RI, Woo V, McFarlane PA, Hegele RA, Tobe SW; Canadian Hypertension Education Program.

Can J Cardiol. 2010 May;26(5):249-58. Review.

50.

The 2010 Canadian Hypertension Education Program recommendations for the management of hypertension: part I - blood pressure measurement, diagnosis and assessment of risk.

Quinn RR, Hemmelgarn BR, Padwal RS, Myers MG, Cloutier L, Bolli P, McKay DW, Khan NA, Hill MD, Mahon J, Hackam DG, Grover S, Wilson T, Penner B, Burgess E, McAlister FA, Lamarre-Cliche M, McLean D, Schiffrin EL, Honos G, Mann K, Tremblay G, Milot A, Chockalingam A, Rabkin SW, Dawes M, Touyz RM, Burns KD, Ruzicka M, Campbell NR, Vallée M, Prasad GV, Lebel M, Tobe SW; Canadian Hypertension Education Program.

Can J Cardiol. 2010 May;26(5):241-8. Review.

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