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Items: 1 to 50 of 72

1.

Spatial UBE2N protein expression indicates genomic instability in colorectal cancers.

Gemoll T, Miroll E, Klein O, Lischka A, Eravci M, Thorns C, Habermann JK.

BMC Cancer. 2019 Jul 18;19(1):710. doi: 10.1186/s12885-019-5856-1.

2.

Single Chromosome Aneuploidy Induces Genome-Wide Perturbation of Nuclear Organization and Gene Expression.

Braun R, Ronquist S, Wangsa D, Chen H, Anthuber L, Gemoll T, Wangsa D, Koparde V, Hunn C, Habermann JK, Heselmeyer-Haddad K, Rajapakse I, Ried T.

Neoplasia. 2019 Apr;21(4):401-412. doi: 10.1016/j.neo.2019.02.003. Epub 2019 Mar 22.

3.

Aneuploidy, TP53 mutation, and amplification of MYC correlate with increased intratumor heterogeneity and poor prognosis of breast cancer patients.

Oltmann J, Heselmeyer-Haddad K, Hernandez LS, Meyer R, Torres I, Hu Y, Doberstein N, Killian JK, Petersen D, Zhu YJ, Edelman DC, Meltzer PS, Schwartz R, Gertz EM, Schäffer AA, Auer G, Habermann JK, Ried T.

Genes Chromosomes Cancer. 2018 Apr;57(4):165-175. doi: 10.1002/gcc.22515. Epub 2018 Jan 9.

4.

Claudin-1 expression in cervical cancer.

Hoellen F, Waldmann A, Banz-Jansen C, Holtrich U, Karn T, Oberländer M, Habermann JK, Hörmann M, Köster F, Ribbat-Idel J, Thill M, Rody A, El-Balat A, Hanker L.

Mol Clin Oncol. 2017 Nov;7(5):880-884. doi: 10.3892/mco.2017.1391. Epub 2017 Aug 25.

5.

EB1 protein alteration characterizes sporadic but not ulcerative colitis associated colorectal cancer.

Gemoll T, Kollbeck SL, Karstens KF, Hò GG, Hartwig S, Strohkamp S, Schillo K, Thorns C, Oberländer M, Kalies K, Lehr S, Habermann JK.

Oncotarget. 2017 Jul 4;8(33):54939-54950. doi: 10.18632/oncotarget.18978. eCollection 2017 Aug 15.

6.

Protein levels of clusterin and glutathione synthetase in platelets allow for early detection of colorectal cancer.

Strohkamp S, Gemoll T, Humborg S, Hartwig S, Lehr S, Freitag-Wolf S, Becker S, Franzén B, Pries R, Wollenberg B, Roblick UJ, Bruch HP, Keck T, Auer G, Habermann JK.

Cell Mol Life Sci. 2018 Jan;75(2):323-334. doi: 10.1007/s00018-017-2631-9. Epub 2017 Aug 28.

PMID:
28849249
7.

Sialylation of IgG antibodies inhibits IgG-mediated allergic reactions.

Epp A, Hobusch J, Bartsch YC, Petry J, Lilienthal GM, Koeleman CAM, Eschweiler S, Möbs C, Hall A, Morris SC, Braumann D, Engellenner C, Bitterling J, Rahmöller J, Leliavski A, Thurmann R, Collin M, Moremen KW, Strait RT, Blanchard V, Petersen A, Gemoll T, Habermann JK, Petersen F, Nandy A, Kahlert H, Hertl M, Wuhrer M, Pfützner W, Jappe U, Finkelman FD, Ehlers M.

J Allergy Clin Immunol. 2018 Jan;141(1):399-402.e8. doi: 10.1016/j.jaci.2017.06.021. Epub 2017 Jul 18. No abstract available.

8.

HLJ1 (DNAJB4) Gene Is a Novel Biomarker Candidate in Breast Cancer.

Acun T, Doberstein N, Habermann JK, Gemoll T, Thorns C, Oztas E, Ried T.

OMICS. 2017 May;21(5):257-265. doi: 10.1089/omi.2017.0016.

9.

Cell-Derived Nanoparticles are Endogenous Modulators of Sepsis With Therapeutic Potential.

Kunz N, Xia BT, Kalies KU, Klinger M, Gemoll T, Habermann JK, Whitacre BE, Seitz AP, Kalies K, Caldwell CC.

Shock. 2017 Sep;48(3):346-354. doi: 10.1097/SHK.0000000000000855.

10.

Combining aneuploidy and dysplasia for colitis' cancer risk assessment outperforms current surveillance efficiency: a meta-analysis.

Meyer R, Freitag-Wolf S, Blindow S, Büning J, Habermann JK.

Int J Colorectal Dis. 2017 Feb;32(2):171-182. doi: 10.1007/s00384-016-2684-5. Epub 2016 Oct 20.

PMID:
27766414
11.

Expression of cyclooxygenase-2 in cervical cancer is associated with lymphovascular invasion.

Hoellen F, Waldmann A, Banz-Jansen C, Rody A, Heide M, Köster F, Ribbat-Idel J, Thorns C, Gebhard M, Oberländer M, Habermann JK, Thill M.

Oncol Lett. 2016 Oct;12(4):2351-2356. Epub 2016 Jul 29.

12.

Concentration of circulating miRNA-containing particles in serum enhances miRNA detection and reflects CRC tissue-related deregulations.

ElSharawy A, Röder C, Becker T, Habermann JK, Schreiber S, Rosenstiel P, Kalthoff H.

Oncotarget. 2016 Nov 15;7(46):75353-75365. doi: 10.18632/oncotarget.12205.

13.

Metadata Repository for Improved Data Sharing and Reuse Based on HL7 FHIR.

Ulrich H, Kock AK, Duhm-Harbeck P, Habermann JK, Ingenerf J.

Stud Health Technol Inform. 2016;228:162-6.

PMID:
27577363
14.

Possibilities and limitations of 2DE-based analyses for identifying low-abundant tumor markers in human serum and plasma.

Strohkamp S, Gemoll T, Habermann JK.

Proteomics. 2016 Oct;16(19):2519-2532. doi: 10.1002/pmic.201600154. Epub 2016 Sep 12. Review.

PMID:
27377442
15.

MALDI-imaging reveals thymosin beta-4 as an independent prognostic marker for colorectal cancer.

Gemoll T, Strohkamp S, Schillo K, Thorns C, Habermann JK.

Oncotarget. 2015 Dec 22;6(41):43869-80. doi: 10.18632/oncotarget.6103.

16.

Genetic Instability and Disease Prognostication.

Gemoll T, Auer G, Ried T, Habermann JK.

Recent Results Cancer Res. 2015;200:81-94. doi: 10.1007/978-3-319-20291-4_4. Review.

PMID:
26376873
17.

Applying Genomics and Proteomics in Translational Surgical Oncology Research.

Gemoll T, Meyer R, Habermann JK.

Eur Surg Res. 2015;55(3):184-97. doi: 10.1159/000438860. Epub 2015 Sep 5. Review.

PMID:
26339997
18.

Diversity of assessing circulating tumor cells (CTCs) emphasizes need for standardization: a CTC Guide to design and report trials.

Bünger S, Zimmermann M, Habermann JK.

Cancer Metastasis Rev. 2015 Sep;34(3):527-45. doi: 10.1007/s10555-015-9582-0. Review.

PMID:
26323491
19.

Increased cathepsin D protein expression is a biomarker for osteosarcomas, pulmonary metastases and other bone malignancies.

Gemoll T, Epping F, Heinrich L, Fritzsche B, Roblick UJ, Szymczak S, Hartwig S, Depping R, Bruch HP, Thorns C, Lehr S, Paech A, Habermann JK.

Oncotarget. 2015 Jun 30;6(18):16517-26.

20.

Cold-Plasma Coagulation on the Surface of the Small Bowel Is Safe in Pigs.

Hoffmann M, Ulrich A, Habermann JK, Bouchard R, Laubert T, Bruch HP, Keck T, Schloericke E.

Surg Innov. 2016 Feb;23(1):7-13. doi: 10.1177/1553350615592753. Epub 2015 Jul 3.

PMID:
26142417
21.

Stage-specific frequency and prognostic significance of aneuploidy in patients with sporadic colorectal cancer--a meta-analysis and current overview.

Laubert T, Freitag-Wolf S, Linnebacher M, König A, Vollmar B, Habermann JK; North German Tumorbank of Colorectal Cancer (ColoNet) consortium.

Int J Colorectal Dis. 2015 Aug;30(8):1015-28. doi: 10.1007/s00384-015-2259-x. Epub 2015 Jun 9. Review.

PMID:
26054386
22.

Assessing quality and functionality of DNA isolated from FFPE tissues through external quality assessment in tissue banks.

Ahmad-Nejad P, Duda A, Sucker A, Werner M, Bronsert P, Stickeler E, Reifenberger G, Malzkorn B, Oberländer M, Habermann JK, Bruch HP, Linnebacher M, Schadendorf D, Neumaier M.

Clin Chem Lab Med. 2015 Nov;53(12):1927-34. doi: 10.1515/cclm-2014-1202.

PMID:
26053008
23.

Colorectal neoplasia in IBD--a single-center analysis of patients undergoing proctocolectomy.

Meyer R, Laubert T, Sommer M, Benecke C, Lehnert H, Fellermann K, Bruch HP, Keck T, Thorns C, Habermann JK, Büning J.

Int J Colorectal Dis. 2015 Jun;30(6):821-9. doi: 10.1007/s00384-015-2217-7. Epub 2015 Apr 26.

PMID:
25913799
24.

Single-cell genetic analysis reveals insights into clonal development of prostate cancers and indicates loss of PTEN as a marker of poor prognosis.

Heselmeyer-Haddad KM, Berroa Garcia LY, Bradley A, Hernandez L, Hu Y, Habermann JK, Dumke C, Thorns C, Perner S, Pestova E, Burke C, Chowdhury SA, Schwartz R, Schäffer AA, Paris PL, Ried T.

Am J Pathol. 2014 Oct;184(10):2671-86. doi: 10.1016/j.ajpath.2014.06.030. Epub 2014 Aug 14.

25.

A novel multiplex-protein array for serum diagnostics of colorectal cancer: impact of pre-analytical storage conditions.

Bünger S, Klempt-Giessing K, Toner V, Kelly M, FitzGerald SP, Brenner H, von Eggeling F, Habermann JK.

Biopreserv Biobank. 2013 Dec;11(6):379-86. doi: 10.1089/bio.2013.0050. Epub 2013 Nov 22.

PMID:
24835368
26.

Global microRNA profiling of pancreatic neuroendocrine neoplasias.

Thorns C, Schurmann C, Gebauer N, Wallaschofski H, Kümpers C, Bernard V, Feller AC, Keck T, Habermann JK, Begum N, Lehnert H, Brabant G.

Anticancer Res. 2014 May;34(5):2249-54.

PMID:
24778027
27.

A 'waterfall' transfer-based workflow for improved quality of tissue microarray construction and processing in breast cancer research.

Oberländer M, Alkemade H, Bünger S, Ernst F, Thorns C, Braunschweig T, Habermann JK.

Pathol Oncol Res. 2014 Jul;20(3):719-26. doi: 10.1007/s12253-014-9752-3. Epub 2014 Mar 7.

PMID:
24619867
28.

Chromosomal aneuploidy affects the global proteome equilibrium of colorectal cancer cells.

Gemoll T, Habermann JK, Becker S, Szymczak S, Upender MB, Bruch HP, Hellman U, Ried T, Auer G, Jörnvall H, Roblick UJ.

Anal Cell Pathol (Amst). 2013;36(5-6):149-61. doi: 10.3233/ACP-140088.

29.

Expression of DIAPH1 is up-regulated in colorectal cancer and its down-regulation strongly reduces the metastatic capacity of colon carcinoma cells.

Lin YN, Izbicki JR, König A, Habermann JK, Blechner C, Lange T, Schumacher U, Windhorst S.

Int J Cancer. 2014 Apr 1;134(7):1571-82. doi: 10.1002/ijc.28486. Epub 2013 Oct 8.

30.

The impact of pre-analytical conditions on the serum proteome: heat-stabilization versus nitrogen storage.

Gemoll T, Löwe O, Borén M, Oberländer M, Hartwig S, Lehr S, Roblick UJ, Auer G, Jörnvall H, Habermann JK.

Arch Physiol Biochem. 2013 Jul;119(3):100-7. doi: 10.3109/13813455.2013.806556. Epub 2013 Jul 4.

PMID:
23826811
31.

Aneuploidy characterizes adjacent non-malignant mucosa of ulcerative colitis-associated but not sporadic colorectal carcinomas: a matched-pair analysis.

Meyer KF, Nause SL, Freitag-Wolf S, Krüger S, Bruch HP, Roblick UJ, Habermann JK.

Scand J Gastroenterol. 2013 Jun;48(6):679-87. doi: 10.3109/00365521.2013.783103. Epub 2013 Apr 2.

PMID:
23544594
32.

Aneuploidy-associated gene expression signatures characterize malignant transformation in ulcerative colitis.

Gerling M, Nousiainen K, Hautaniemi S, Krüger S, Fritzsche B, Homann N, Bruch HP, Auer G, Roblick UJ, Ried T, Habermann JK.

Inflamm Bowel Dis. 2013 Mar-Apr;19(4):691-703. doi: 10.1097/MIB.0b013e31827eeaa4.

PMID:
23455720
33.

Aneuploidy and elevated CEA indicate an increased risk for metachronous metastasis in colorectal cancer.

Laubert T, Bente V, Freitag-Wolf S, Voulgaris H, Oberländer M, Schillo K, Kleemann M, Bürk C, Bruch HP, Roblick UJ, Habermann JK.

Int J Colorectal Dis. 2013 Jun;28(6):767-75. doi: 10.1007/s00384-012-1625-1. Epub 2013 Jan 8.

PMID:
23296402
34.

The "North German Tumor Bank of Colorectal Cancer": status report after the first 2 years of support by the German Cancer Aid Foundation.

Oberländer M, Linnebacher M, König A, Bogoevska V, Brodersen C, Kaatz R, Krohn M, Hackmann M, Ingenerf J, Christoph J, Mate S, Prokosch HU, Yekebas EF, Thorns C, Büning J, Prall F, Uhlig R, Roblick UJ, Izbicki JR, Klar E, Bruch HP, Vollmar B, Habermann JK; ColoNet consortium.

Langenbecks Arch Surg. 2013 Feb;398(2):251-8. doi: 10.1007/s00423-012-1043-4. Epub 2013 Jan 8.

PMID:
23292500
35.

A novel multiplex-protein array for serum diagnostics of colon cancer: a case-control study.

Bünger S, Haug U, Kelly M, Posorski N, Klempt-Giessing K, Cartwright A, Fitzgerald SP, Toner V, McAleer D, Gemoll T, Laubert T, Büning J, Fellermann K, Bruch HP, Roblick UJ, Brenner H, von Eggeling F, Habermann JK.

BMC Cancer. 2012 Sep 7;12:393. doi: 10.1186/1471-2407-12-393.

36.

Pancreatic carcinoma cell lines reflect frequency and variability of cancer stem cell markers in clinical tissue.

Bünger S, Barow M, Thorns C, Freitag-Wolf S, Danner S, Tiede S, Pries R, Görg S, Bruch HP, Roblick UJ, Kruse C, Habermann JK.

Eur Surg Res. 2012;49(2):88-98. doi: 10.1159/000341669. Epub 2012 Aug 30.

PMID:
22948659
37.

Designing and implementing a biobanking IT framework for multiple research scenarios.

Prokosch HU, Mate S, Christoph J, Beck A, Köpcke F, Stephan S, Beckmann MW, Rau T, Hartmann A, Wullich B, Breil B, Eckardt KU, Titze S, Habermann JK, Ingenerf J, Hackmann M, Ries M, Bürkle T, Ganslandt T.

Stud Health Technol Inform. 2012;180:559-63.

PMID:
22874253
38.

Metachronous metastasis- and survival-analysis show prognostic importance of lymphadenectomy for colon carcinomas.

Laubert T, Habermann JK, Hemmelmann C, Kleemann M, Oevermann E, Bouchard R, Hildebrand P, Jungbluth T, Bürk C, Esnaashari H, Schlöricke E, Hoffmann M, Ziegler A, Bruch HP, Roblick UJ.

BMC Gastroenterol. 2012 Mar 23;12:24. doi: 10.1186/1471-230X-12-24.

39.

The application of cold-plasma coagulation on the visceral pleura results in a predictable depth of necrosis without fistula generation.

Hoffmann M, Ulrich A, Schloericke E, Limmer S, Habermann JK, Wolken H, Bruch HP, Kujath P.

Interact Cardiovasc Thorac Surg. 2012 Mar;14(3):239-43. doi: 10.1093/icvts/ivr109. Epub 2011 Dec 22.

40.

Genomic instability influences the transcriptome and proteome in endometrial cancer subtypes.

Habermann JK, Bündgen NK, Gemoll T, Hautaniemi S, Lundgren C, Wangsa D, Doering J, Bruch HP, Nordstroem B, Roblick UJ, Jörnvall H, Auer G, Ried T.

Mol Cancer. 2011 Oct 31;10:132. doi: 10.1186/1476-4598-10-132.

41.

A novel xenogeneic co-culture system to examine neuronal differentiation capability of various adult human stem cells.

Petschnik AE, Fell B, Tiede S, Habermann JK, Pries R, Kruse C, Danner S.

PLoS One. 2011;6(9):e24944. doi: 10.1371/journal.pone.0024944. Epub 2011 Sep 14.

42.

MALDI mass spectrometry imaging in oncology (Review).

Gemoll T, Roblick UJ, Habermann JK.

Mol Med Rep. 2011 Nov-Dec;4(6):1045-51. doi: 10.3892/mmr.2011.566. Epub 2011 Aug 22. Review.

PMID:
21874241
43.

Toward standardized high-throughput serum diagnostics: multiplex-protein array identifies IL-8 and VEGF as serum markers for colon cancer.

Bünger S, Haug U, Kelly FM, Klempt-Giessing K, Cartwright A, Posorski N, Dibbelt L, Fitzgerald SP, Bruch HP, Roblick UJ, von Eggeling F, Brenner H, Habermann JK; BMBF-Consortium "Colorectal Cancer Screening Chip".

J Biomol Screen. 2011 Oct;16(9):1018-26. doi: 10.1177/1087057111414894. Epub 2011 Aug 1.

PMID:
21807963
44.

Characterization of chromosomal instability in murine colitis-associated colorectal cancer.

Gerling M, Glauben R, Habermann JK, Kühl AA, Loddenkemper C, Lehr HA, Zeitz M, Siegmund B.

PLoS One. 2011;6(7):e22114. doi: 10.1371/journal.pone.0022114. Epub 2011 Jul 22.

45.

Protein profiling of genomic instability in endometrial cancer.

Gemoll T, Habermann JK, Lahmann J, Szymczak S, Lundgren C, Bündgen NK, Jungbluth T, Nordström B, Becker S, Lomnytska MI, Bruch HP, Ziegler A, Hellman U, Auer G, Roblick UJ, Jörnvall H.

Cell Mol Life Sci. 2012 Jan;69(2):325-33. doi: 10.1007/s00018-011-0752-0. Epub 2011 Jul 8.

PMID:
21739232
46.

HDAC2 and TXNL1 distinguish aneuploid from diploid colorectal cancers.

Gemoll T, Roblick UJ, Szymczak S, Braunschweig T, Becker S, Igl BW, Bruch HP, Ziegler A, Hellman U, Difilippantonio MJ, Ried T, Jörnvall H, Auer G, Habermann JK.

Cell Mol Life Sci. 2011 Oct;68(19):3261-74. doi: 10.1007/s00018-011-0628-3. Epub 2011 Feb 3.

47.

Serum biomarkers for improved diagnostic of pancreatic cancer: a current overview.

Bünger S, Laubert T, Roblick UJ, Habermann JK.

J Cancer Res Clin Oncol. 2011 Mar;137(3):375-89. doi: 10.1007/s00432-010-0965-x. Epub 2010 Dec 31. Review.

PMID:
21193998
48.

A 12-gene genomic instability signature predicts clinical outcomes in multiple cancer types.

Mettu RK, Wan YW, Habermann JK, Ried T, Guo NL.

Int J Biol Markers. 2010 Oct-Dec;25(4):219-28.

49.

Genomic instability and oncogene amplifications in colorectal adenomas predict recurrence and synchronous carcinoma.

Habermann JK, Brucker CA, Freitag-Wolf S, Heselmeyer-Haddad K, Krüger S, Barenboim L, Downing T, Bruch HP, Auer G, Roblick UJ, Ried T.

Mod Pathol. 2011 Apr;24(4):542-55. doi: 10.1038/modpathol.2010.217. Epub 2010 Nov 19.

50.

SELDI-TOF serum proteomics and colorectal cancer: a current overview.

Gemoll T, Roblick UJ, Auer G, Jörnvall H, Habermann JK.

Arch Physiol Biochem. 2010 Oct-Dec;116(4-5):188-96. doi: 10.3109/13813455.2010.495130. Epub 2010 Jul 8. Review.

PMID:
20615064

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