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Items: 1 to 50 of 85

1.

Common matrix metalloproteinase-2 gene variants and altered susceptibility to breast cancer and associated features in Tunisian women.

Habel AF, Ghali RM, Bouaziz H, Daldoul A, Hadj-Ahmed M, Mokrani A, Zaied S, Hechiche M, Rahal K, Yacoubi-Loueslati B, Almawi WY.

Tumour Biol. 2019 Apr;41(4):1010428319845749. doi: 10.1177/1010428319845749.

PMID:
31014197
2.

DNA methylation profiling is a method of choice for molecular verification of pediatric WNT-activated medulloblastomas.

Korshunov A, Sahm F, Zheludkova O, Golanov A, Stichel D, Schrimpf D, Ryzhova M, Potapov A, Habel A, Meyer J, Lichter P, Jones DTW, von Deimling A, Pfister SM, Kool M.

Neuro Oncol. 2019 Feb 14;21(2):214-221. doi: 10.1093/neuonc/noy155.

PMID:
30252101
3.

Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate.

Bunse L, Pusch S, Bunse T, Sahm F, Sanghvi K, Friedrich M, Alansary D, Sonner JK, Green E, Deumelandt K, Kilian M, Neftel C, Uhlig S, Kessler T, von Landenberg A, Berghoff AS, Marsh K, Steadman M, Zhu D, Nicolay B, Wiestler B, Breckwoldt MO, Al-Ali R, Karcher-Bausch S, Bozza M, Oezen I, Kramer M, Meyer J, Habel A, Eisel J, Poschet G, Weller M, Preusser M, Nadji-Ohl M, Thon N, Burger MC, Harter PN, Ratliff M, Harbottle R, Benner A, Schrimpf D, Okun J, Herold-Mende C, Turcan S, Kaulfuss S, Hess-Stumpp H, Bieback K, Cahill DP, Plate KH, Hänggi D, Dorsch M, Suvà ML, Niemeyer BA, von Deimling A, Wick W, Platten M.

Nat Med. 2018 Aug;24(8):1192-1203. doi: 10.1038/s41591-018-0095-6. Epub 2018 Jul 9.

PMID:
29988124
4.

Epithelioid glioblastomas stratify into established diagnostic subsets upon integrated molecular analysis.

Korshunov A, Chavez L, Sharma T, Ryzhova M, Schrimpf D, Stichel D, Capper D, Sturm D, Kool M, Habel A, Kleinschmidt-DeMasters BK, Rosenblum M, Absalyamova O, Golanov A, Lichter P, Pfister SM, Jones DTW, Perry A, von Deimling A.

Brain Pathol. 2018 Sep;28(5):656-662. doi: 10.1111/bpa.12566. Epub 2017 Oct 30.

PMID:
28990704
5.

A Highly Conserved Basidiomycete Peptide Synthetase Produces a Trimeric Hydroxamate Siderophore.

Brandenburger E, Gressler M, Leonhardt R, Lackner G, Habel A, Hertweck C, Brock M, Hoffmeister D.

Appl Environ Microbiol. 2017 Oct 17;83(21). pii: e01478-17. doi: 10.1128/AEM.01478-17. Print 2017 Nov 1.

6.

H3-/IDH-wild type pediatric glioblastoma is comprised of molecularly and prognostically distinct subtypes with associated oncogenic drivers.

Korshunov A, Schrimpf D, Ryzhova M, Sturm D, Chavez L, Hovestadt V, Sharma T, Habel A, Burford A, Jones C, Zheludkova O, Kumirova E, Kramm CM, Golanov A, Capper D, von Deimling A, Pfister SM, Jones DTW.

Acta Neuropathol. 2017 Sep;134(3):507-516. doi: 10.1007/s00401-017-1710-1. Epub 2017 Apr 11.

PMID:
28401334
7.

Draft Genome Sequence and Gene Annotation of the Entomopathogenic Fungus Verticillium hemipterigenum.

Horn F, Habel A, Scharf DH, Dworschak J, Brakhage AA, Guthke R, Hertweck C, Linde J.

Genome Announc. 2015 Jan 22;3(1). pii: e01439-14. doi: 10.1128/genomeA.01439-14.

8.

The influence of social support from the family on health related-quality of life in persons with a colostomy.

Leyk M, Ksiaz˙ek J, Habel A, Dobosz M, Kruk A, Terech S.

J Wound Ostomy Continence Nurs. 2014 Nov-Dec;41(6):581-8. doi: 10.1097/WON.0000000000000086.

PMID:
25377109
9.

Opposed effects of enzymatic gliotoxin N- and S-methylations.

Scharf DH, Habel A, Heinekamp T, Brakhage AA, Hertweck C.

J Am Chem Soc. 2014 Aug 20;136(33):11674-9. doi: 10.1021/ja5033106. Epub 2014 Aug 7.

PMID:
25062268
10.

Neurofibromin specific antibody differentiates malignant peripheral nerve sheath tumors (MPNST) from other spindle cell neoplasms.

Reuss DE, Habel A, Hagenlocher C, Mucha J, Ackermann U, Tessmer C, Meyer J, Capper D, Moldenhauer G, Mautner V, Frappart PO, Schittenhelm J, Hartmann C, Hagel C, Katenkamp K, Petersen I, Mechtersheimer G, von Deimling A.

Acta Neuropathol. 2014 Apr;127(4):565-72. doi: 10.1007/s00401-014-1246-6. Epub 2014 Jan 25.

PMID:
24464231
11.

Flavoenzyme-catalyzed formation of disulfide bonds in natural products.

Scharf DH, Groll M, Habel A, Heinekamp T, Hertweck C, Brakhage AA, Huber EM.

Angew Chem Int Ed Engl. 2014 Feb 17;53(8):2221-4. doi: 10.1002/anie.201309302. Epub 2014 Jan 20.

PMID:
24446392
12.

Towards a safety net for management of 22q11.2 deletion syndrome: guidelines for our times.

Habel A, Herriot R, Kumararatne D, Allgrove J, Baker K, Baxendale H, Bu'Lock F, Firth H, Gennery A, Holland A, Illingworth C, Mercer N, Pannebakker M, Parry A, Roberts A, Tsai-Goodman B.

Eur J Pediatr. 2014 Jun;173(6):757-65. doi: 10.1007/s00431-013-2240-z. Epub 2014 Jan 3.

13.

AKT1E17K mutations cluster with meningothelial and transitional meningiomas and can be detected by SFRP1 immunohistochemistry.

Sahm F, Bissel J, Koelsche C, Schweizer L, Capper D, Reuss D, Böhmer K, Lass U, Göck T, Kalis K, Meyer J, Habel A, Brehmer S, Mittelbronn M, Jones DT, Schittenhelm J, Urbschat S, Ketter R, Heim S, Mawrin C, Hainfellner JA, Berghoff AS, Preusser M, Becker A, Herold-Mende C, Unterberg A, Hartmann C, Kickingereder P, Collins VP, Pfister SM, von Deimling A.

Acta Neuropathol. 2013 Nov;126(5):757-62. doi: 10.1007/s00401-013-1187-5. Epub 2013 Oct 6.

PMID:
24096618
14.

A recombinant measles vaccine expressing chikungunya virus-like particles is strongly immunogenic and protects mice from lethal challenge with chikungunya virus.

Brandler S, Ruffié C, Combredet C, Brault JB, Najburg V, Prevost MC, Habel A, Tauber E, Desprès P, Tangy F.

Vaccine. 2013 Aug 12;31(36):3718-25. doi: 10.1016/j.vaccine.2013.05.086. Epub 2013 Jun 4.

PMID:
23742993
15.

Meningeal hemangiopericytoma and solitary fibrous tumors carry the NAB2-STAT6 fusion and can be diagnosed by nuclear expression of STAT6 protein.

Schweizer L, Koelsche C, Sahm F, Piro RM, Capper D, Reuss DE, Pusch S, Habel A, Meyer J, Göck T, Jones DT, Mawrin C, Schittenhelm J, Becker A, Heim S, Simon M, Herold-Mende C, Mechtersheimer G, Paulus W, König R, Wiestler OD, Pfister SM, von Deimling A.

Acta Neuropathol. 2013 May;125(5):651-8. doi: 10.1007/s00401-013-1117-6. Epub 2013 Apr 11.

PMID:
23575898
16.

BRAFV600E mutant protein is expressed in cells of variable maturation in Langerhans cell histiocytosis.

Sahm F, Capper D, Preusser M, Meyer J, Stenzinger A, Lasitschka F, Berghoff AS, Habel A, Schneider M, Kulozik A, Anagnostopoulos I, Müllauer L, Mechtersheimer G, von Deimling A.

Blood. 2012 Sep 20;120(12):e28-34. Epub 2012 Aug 2.

17.

Syndrome-specific growth charts for 22q11.2 deletion syndrome in Caucasian children.

Habel A, McGinn MJ 2nd, Zackai EH, Unanue N, McDonald-McGinn DM.

Am J Med Genet A. 2012 Nov;158A(11):2665-71. doi: 10.1002/ajmg.a.35426. Epub 2012 Jun 18.

PMID:
22711268
18.

Addressing diffuse glioma as a systemic brain disease with single-cell analysis.

Sahm F, Capper D, Jeibmann A, Habel A, Paulus W, Troost D, von Deimling A.

Arch Neurol. 2012 Apr;69(4):523-6. doi: 10.1001/archneurol.2011.2910. Epub 2011 Dec 12.

PMID:
22158715
19.

Immunohistochemical testing of BRAF V600E status in 1,120 tumor tissue samples of patients with brain metastases.

Capper D, Berghoff AS, Magerle M, Ilhan A, Wöhrer A, Hackl M, Pichler J, Pusch S, Meyer J, Habel A, Petzelbauer P, Birner P, von Deimling A, Preusser M.

Acta Neuropathol. 2012 Feb;123(2):223-33. doi: 10.1007/s00401-011-0887-y. Epub 2011 Oct 20.

PMID:
22012135
20.

A dedicated glutathione S-transferase mediates carbon-sulfur bond formation in gliotoxin biosynthesis.

Scharf DH, Remme N, Habel A, Chankhamjon P, Scherlach K, Heinekamp T, Hortschansky P, Brakhage AA, Hertweck C.

J Am Chem Soc. 2011 Aug 17;133(32):12322-5. doi: 10.1021/ja201311d. Epub 2011 Jul 22.

PMID:
21749092
21.

Similar efficacy of raltegravir when used with or without a protease inhibitor in treatment-experienced patients.

Skiest DJ, Cohen C, Mounzer K, Haigney Z, Barker D, Gottlieb M, Bellman PC, Dejesus E, Khanlou H, Ruane PJ, Hsiao CB, Abriola K, Rashbaum B, Bellos N, Ward D, Colson A, Santiago F, Habel A, Garb J.

HIV Clin Trials. 2011 May-Jun;12(3):131-40. doi: 10.1310/hct1203-131.

PMID:
21684853
22.

Assessment of BRAF V600E mutation status by immunohistochemistry with a mutation-specific monoclonal antibody.

Capper D, Preusser M, Habel A, Sahm F, Ackermann U, Schindler G, Pusch S, Mechtersheimer G, Zentgraf H, von Deimling A.

Acta Neuropathol. 2011 Jul;122(1):11-9. doi: 10.1007/s00401-011-0841-z. Epub 2011 Jun 3.

PMID:
21638088
23.

Practical guidelines for managing patients with 22q11.2 deletion syndrome.

Bassett AS, McDonald-McGinn DM, Devriendt K, Digilio MC, Goldenberg P, Habel A, Marino B, Oskarsdottir S, Philip N, Sullivan K, Swillen A, Vorstman J; International 22q11.2 Deletion Syndrome Consortium.

J Pediatr. 2011 Aug;159(2):332-9.e1. doi: 10.1016/j.jpeds.2011.02.039. Epub 2011 May 12. No abstract available.

24.

Conformational studies on the Delta8(E,Z)-sphingolipid desaturase from Helianthus annuus with chiral fluoropalmitic acids as mechanistic probes.

Habel A, Sperling P, Bartram S, Heinz E, Boland W.

J Org Chem. 2010 Aug 6;75(15):4975-82. doi: 10.1021/jo100542q.

PMID:
20575587
25.

Core neuropsychological characteristics of children and adolescents with 22q11.2 deletion.

Jacobson C, Shearer J, Habel A, Kane F, Tsakanikos E, Kravariti E.

J Intellect Disabil Res. 2010 Aug;54(8):701-13. doi: 10.1111/j.1365-2788.2010.01298.x. Epub 2010 Jun 17.

PMID:
20561146
26.

Memory in intellectually matched groups of young participants with 22q11.2 deletion syndrome and those with schizophrenia.

Kravariti E, Jacobson C, Morris R, Frangou S, Murray RM, Tsakanikos E, Habel A, Shearer J.

Res Dev Disabil. 2010 May-Jun;31(3):864-8. doi: 10.1016/j.ridd.2010.03.003. Epub 2010 Mar 21.

PMID:
20307954
27.

Characterization of R132H mutation-specific IDH1 antibody binding in brain tumors.

Capper D, Weissert S, Balss J, Habel A, Meyer J, Jäger D, Ackermann U, Tessmer C, Korshunov A, Zentgraf H, Hartmann C, von Deimling A.

Brain Pathol. 2010 Jan;20(1):245-54. doi: 10.1111/j.1750-3639.2009.00352.x. Epub 2009 Oct 27.

PMID:
19903171
28.

Daidzein overcomes TRAIL-resistance in malignant glioma cells by modulating the expression of the intrinsic apoptotic inhibitor, bcl-2.

Siegelin MD, Gaiser T, Habel A, Siegelin Y.

Neurosci Lett. 2009 May 1;454(3):223-8. doi: 10.1016/j.neulet.2009.03.031. Epub 2009 Mar 14.

PMID:
19429088
29.

p53-mediated inhibition of angiogenesis in diffuse low-grade astrocytomas.

Gaiser T, Becker MR, Meyer J, Habel A, Siegelin MD.

Neurochem Int. 2009 Jun;54(7):458-63. doi: 10.1016/j.neuint.2009.01.016. Epub 2009 Feb 6.

PMID:
19428789
30.

Myricetin sensitizes malignant glioma cells to TRAIL-mediated apoptosis by down-regulation of the short isoform of FLIP and bcl-2.

Siegelin MD, Gaiser T, Habel A, Siegelin Y.

Cancer Lett. 2009 Oct 8;283(2):230-8. doi: 10.1016/j.canlet.2009.04.002. Epub 2009 Apr 26.

PMID:
19398149
31.

KAAD-cyclopamine augmented TRAIL-mediated apoptosis in malignant glioma cells by modulating the intrinsic and extrinsic apoptotic pathway.

Siegelin MD, Siegelin Y, Habel A, Rami A, Gaiser T.

Neurobiol Dis. 2009 May;34(2):259-66.

PMID:
19385057
32.

Genistein enhances proteasomal degradation of the short isoform of FLIP in malignant glioma cells and thereby augments TRAIL-mediated apoptosis.

Siegelin MD, Siegelin Y, Habel A, Gaiser T.

Neurosci Lett. 2009 Apr 3;453(2):92-7. doi: 10.1016/j.neulet.2009.02.018. Epub 2009 Feb 13.

PMID:
19356600
33.

Stem-cell-like glioma cells are resistant to TRAIL/Apo2L and exhibit down-regulation of caspase-8 by promoter methylation.

Capper D, Gaiser T, Hartmann C, Habel A, Mueller W, Herold-Mende C, von Deimling A, Siegelin MD.

Acta Neuropathol. 2009 Apr;117(4):445-56. doi: 10.1007/s00401-009-0494-3. Epub 2009 Feb 12.

PMID:
19214542
34.

17-AAG sensitized malignant glioma cells to death-receptor mediated apoptosis.

Siegelin MD, Habel A, Gaiser T.

Neurobiol Dis. 2009 Feb;33(2):243-9. doi: 10.1016/j.nbd.2008.10.005. Epub 2008 Nov 10.

PMID:
19027068
35.

The flavonoid kaempferol sensitizes human glioma cells to TRAIL-mediated apoptosis by proteasomal degradation of survivin.

Siegelin MD, Reuss DE, Habel A, Herold-Mende C, von Deimling A.

Mol Cancer Ther. 2008 Nov;7(11):3566-74. doi: 10.1158/1535-7163.MCT-08-0236.

36.

Quercetin promotes degradation of survivin and thereby enhances death-receptor-mediated apoptosis in glioma cells.

Siegelin MD, Reuss DE, Habel A, Rami A, von Deimling A.

Neuro Oncol. 2009 Apr;11(2):122-31. doi: 10.1215/15228517-2008-085. Epub 2008 Oct 29.

37.

Epigalocatechin-3-gallate (EGCG) downregulates PEA15 and thereby augments TRAIL-mediated apoptosis in malignant glioma.

Siegelin MD, Habel A, Gaiser T.

Neurosci Lett. 2008 Dec 19;448(1):161-5. doi: 10.1016/j.neulet.2008.10.036. Epub 2008 Oct 17.

PMID:
18948169
38.

TRAIL-mediated apoptosis in malignant glioma cells is augmented by celecoxib through proteasomal degradation of survivin.

Gaiser T, Becker MR, Habel A, Reuss DE, Ehemann V, Rami A, Siegelin MD.

Neurosci Lett. 2008 Sep 12;442(2):109-13. doi: 10.1016/j.neulet.2008.07.014. Epub 2008 Jul 10.

PMID:
18634847
39.

Efficient and flexible synthesis of chiral gamma- and delta-lactones.

Habel A, Boland W.

Org Biomol Chem. 2008 May 7;6(9):1601-4. doi: 10.1039/b801514g. Epub 2008 Mar 10.

PMID:
18421392
40.

Discovery of a novel class of highly conserved vaccine antigens using genomic scale antigenic fingerprinting of pneumococcus with human antibodies.

Giefing C, Meinke AL, Hanner M, Henics T, Bui MD, Gelbmann D, Lundberg U, Senn BM, Schunn M, Habel A, Henriques-Normark B, Ortqvist A, Kalin M, von Gabain A, Nagy E.

J Exp Med. 2008 Jan 21;205(1):117-31. doi: 10.1084/jem.20071168. Epub 2007 Dec 31.

41.

Evidence for a radical mechanism of the dechlorination of chlorinated propenes mediated by the tetrachloroethene reductive dehalogenase of Sulfurospirillum muftivorans.

Schmitz RP, Wolf J, Habel A, Neumann A, Ploss K, Svatos A, Boland W, Diekert G.

Environ Sci Technol. 2007 Nov 1;41(21):7370-5.

PMID:
18044513
42.

1-phenylethyl isocyanate is a powerful reagent for the chiral analysis of secondary alcohols and hydroxy fatty acids with remote stereogenic centres.

Habel A, Spiteller D, Boland W.

J Chromatogr A. 2007 Sep 21;1165(1-2):182-90. Epub 2007 Jul 31.

PMID:
17697687
43.

Spinal cord ischemia after endovascular repair of the descending thoracic aorta in a sheep model.

Böckler D, Kotelis D, Kohlhof P, von Tengg-Kobligk H, Mansmann U, Zink W, Hörner C, Ortlepp I, Habel A, Kauczor HU, Graf B, Allenberg JR.

Eur J Vasc Endovasc Surg. 2007 Oct;34(4):461-9. Epub 2007 Aug 1.

44.

The nature of feeding in infants with unrepaired cleft lip and/or palate compared with healthy noncleft infants.

Masarei AG, Sell D, Habel A, Mars M, Sommerlad BC, Wade A.

Cleft Palate Craniofac J. 2007 May;44(3):321-8.

PMID:
17477749
45.

Augmentation of the antimicrobial efficacy of antibiotics by filamentous phage.

Hagens S, Habel A, Bläsi U.

Microb Drug Resist. 2006 Fall;12(3):164-8.

PMID:
17002542
46.

Delayed detection of cleft palate: an audit of newborn examination.

Habel A, Elhadi N, Sommerlad B, Powell J.

Arch Dis Child. 2006 Mar;91(3):238-40. Epub 2005 Dec 13.

47.

Therapy of experimental pseudomonas infections with a nonreplicating genetically modified phage.

Hagens S, Habel A, von Ahsen U, von Gabain A, Bläsi U.

Antimicrob Agents Chemother. 2004 Oct;48(10):3817-22.

48.

Identification of cryptic MHC I-restricted epitopes encoded by HIV-1 alternative reading frames.

Cardinaud S, Moris A, Février M, Rohrlich PS, Weiss L, Langlade-Demoyen P, Lemonnier FA, Schwartz O, Habel A.

J Exp Med. 2004 Apr 19;199(8):1053-63. Epub 2004 Apr 12.

49.

Reduced virulence of a hfq mutant of Pseudomonas aeruginosa O1.

Sonnleitner E, Hagens S, Rosenau F, Wilhelm S, Habel A, Jäger KE, Bläsi U.

Microb Pathog. 2003 Nov;35(5):217-28.

PMID:
14521880
50.

Intravenous salbutamol bolus compared with an aminophylline infusion in children with severe asthma: a randomised controlled trial.

Roberts G, Newsom D, Gomez K, Raffles A, Saglani S, Begent J, Lachman P, Sloper K, Buchdahl R, Habel A; North West Thames Asthma Study Group.

Thorax. 2003 Apr;58(4):306-10.

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