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Mutant GNAS drives pancreatic tumourigenesis by inducing PKA-mediated SIK suppression and reprogramming lipid metabolism.

Patra KC, Kato Y, Mizukami Y, Widholz S, Boukhali M, Revenco I, Grossman EA, Ji F, Sadreyev RI, Liss AS, Screaton RA, Sakamoto K, Ryan DP, Mino-Kenudson M, Castillo CF, Nomura DK, Haas W, Bardeesy N.

Nat Cell Biol. 2018 Jul;20(7):811-822. doi: 10.1038/s41556-018-0122-3. Epub 2018 Jun 25.


Identification of galectin-3 as an autoantigen in patients with IgG4-related disease.

Perugino CA, AlSalem SB, Mattoo H, Della-Torre E, Mahajan V, Ganesh G, Allard-Chamard H, Wallace Z, Montesi SB, Kreuzer J, Haas W, Stone JH, Pillai S.

J Allergy Clin Immunol. 2018 May 29. pii: S0091-6749(18)30768-1. doi: 10.1016/j.jaci.2018.05.011. [Epub ahead of print]


Evaluating Health Co-Benefits of Climate Change Mitigation in Urban Mobility.

Wolkinger B, Haas W, Bachner G, Weisz U, Steininger K, Hutter HP, Delcour J, Griebler R, Mittelbach B, Maier P, Reifeltshammer R.

Int J Environ Res Public Health. 2018 Apr 28;15(5). pii: E880. doi: 10.3390/ijerph15050880.


Find and treat or find and lose? Tuberculosis treatment outcomes among screened newly arrived asylum seekers in Germany 2002 to 2014.

Kuehne A, Hauer B, Brodhun B, Haas W, Fiebig L.

Euro Surveill. 2018 Mar;23(11). doi: 10.2807/1560-7917.ES.2018.23.11.17-00042.


Screening of migrants for tuberculosis identifies patients with multidrug-resistant tuberculosis but is not sufficient.

Helbling P, Kröger S, Haas W, Brusin S, Cirillo DM, Groenheit R, Guthmann JP, Soini H, Hendrickx D, van der Werf MJ.

Clin Microbiol Infect. 2018 Mar 17. pii: S1198-743X(18)30225-8. doi: 10.1016/j.cmi.2018.03.015. [Epub ahead of print] No abstract available.


Integrated in vivo multiomics analysis identifies p21-activated kinase signaling as a driver of colitis.

Lyons J, Brubaker DK, Ghazi PC, Baldwin KR, Edwards A, Boukhali M, Strasser SD, Suarez-Lopez L, Lin YJ, Yajnik V, Kissil JL, Haas W, Lauffenburger DA, Haigis KM.

Sci Signal. 2018 Feb 27;11(519). pii: eaan3580. doi: 10.1126/scisignal.aan3580.


An Enhanced Recovery after Surgery Pathway for Microvascular Breast Reconstruction Is Safe and Effective.

Astanehe A, Temple-Oberle C, Nielsen M, de Haas W, Lindsay R, Matthews J, McKenzie DC, Yeung J, Schrag C.

Plast Reconstr Surg Glob Open. 2018 Jan 18;6(1):e1634. doi: 10.1097/GOX.0000000000001634. eCollection 2018 Jan.


A cluster of multidrug-resistant Mycobacterium tuberculosis among patients arriving in Europe from the Horn of Africa: a molecular epidemiological study.

Walker TM, Merker M, Knoblauch AM, Helbling P, Schoch OD, van der Werf MJ, Kranzer K, Fiebig L, Kröger S, Haas W, Hoffmann H, Indra A, Egli A, Cirillo DM, Robert J, Rogers TR, Groenheit R, Mengshoel AT, Mathys V, Haanperä M, Soolingen DV, Niemann S, Böttger EC, Keller PM; MDR-TB Cluster Consortium.

Lancet Infect Dis. 2018 Apr;18(4):431-440. doi: 10.1016/S1473-3099(18)30004-5. Epub 2018 Jan 8. Erratum in: Lancet Infect Dis. 2018 Jan 10;:.


Pharmacological perturbation of CDK9 using selective CDK9 inhibition or degradation.

Olson CM, Jiang B, Erb MA, Liang Y, Doctor ZM, Zhang Z, Zhang T, Kwiatkowski N, Boukhali M, Green JL, Haas W, Nomanbhoy T, Fischer ES, Young RA, Bradner JE, Winter GE, Gray NS.

Nat Chem Biol. 2018 Feb;14(2):163-170. doi: 10.1038/nchembio.2538. Epub 2017 Dec 18.


E2F/DP Prevents Cell-Cycle Progression in Endocycling Fat Body Cells by Suppressing dATM Expression.

Guarner A, Morris R, Korenjak M, Boukhali M, Zappia MP, Van Rechem C, Whetstine JR, Ramaswamy S, Zou L, Frolov MV, Haas W, Dyson NJ.

Dev Cell. 2017 Dec 18;43(6):689-703.e5. doi: 10.1016/j.devcel.2017.11.008. Epub 2017 Dec 7.


Integration of molecular typing results into tuberculosis surveillance in Germany-A pilot study.

Andrés M, Göhring-Zwacka E, Fiebig L, Priwitzer M, Richter E, Rüsch-Gerdes S, Haas W, Niemann S, Brodhun B.

PLoS One. 2017 Nov 22;12(11):e0188356. doi: 10.1371/journal.pone.0188356. eCollection 2017.


Tuberculosis screening in asylum seekers in Germany, 2015: characteristics of cases and yield.

Fiebig L, Hauer B, Andrés M, Haas W.

Eur Respir J. 2017 Oct 26;50(4). pii: 1602550. doi: 10.1183/13993003.02550-2016. Print 2017 Oct. No abstract available.


[Consensus-Based Guidelines for Diagnosis, Prevention and Treatment of Tuberculosis in Children and Adolescents - A Guideline on Behalf of the German Society for Pediatric Infectious Diseases (DGPI)].

Feiterna-Sperling C, Brinkmann F, Adamczick C, Ahrens F, Barker M, Berger C, Berthold LD, Bogyi M, von Both U, Frischer T, Haas W, Hartmann P, Hillemann D, Hirsch FW, Kranzer K, Kunitz F, Maritz E, Pizzulli A, Ritz N, Schlags R, Spindler T, Thee S, Weizsäcker K.

Pneumologie. 2017 Oct;71(10):629-680. doi: 10.1055/s-0043-116545. Epub 2017 Oct 10. German.


TOX Regulates Growth, DNA Repair, and Genomic Instability in T-cell Acute Lymphoblastic Leukemia.

Lobbardi R, Pinder J, Martinez-Pastor B, Theodorou M, Blackburn JS, Abraham BJ, Namiki Y, Mansour M, Abdelfattah NS, Molodtsov A, Alexe G, Toiber D, de Waard M, Jain E, Boukhali M, Lion M, Bhere D, Shah K, Gutierrez A, Stegmaier K, Silverman LB, Sadreyev RI, Asara JM, Oettinger MA, Haas W, Look AT, Young RA, Mostoslavsky R, Dellaire G, Langenau DM.

Cancer Discov. 2017 Nov;7(11):1336-1353. doi: 10.1158/2159-8290.CD-17-0267. Epub 2017 Oct 3.


Detection of dysregulated protein-association networks by high-throughput proteomics predicts cancer vulnerabilities.

Lapek JD Jr, Greninger P, Morris R, Amzallag A, Pruteanu-Malinici I, Benes CH, Haas W.

Nat Biotechnol. 2017 Oct;35(10):983-989. doi: 10.1038/nbt.3955. Epub 2017 Sep 11.


Response to Comment on "Permanent human occupation of the central Tibetan Plateau in the early Holocene".

Haas WR, Aldenderfer MS, Meyer MC.

Science. 2017 Aug 11;357(6351). pii: eaam9444. doi: 10.1126/science.aam9444.


Response to Comment on "Permanent human occupation of the central Tibetan Plateau in the early Holocene".

Meyer MC, Hoffmann DL, Aldenderfer MS, Haas WR, Dahl JA, Wang Z, Degering D, Schlütz F.

Science. 2017 Aug 11;357(6351). pii: eaan8575. doi: 10.1126/science.aan8575.


Immunological recovery in tuberculosis/HIV co-infected patients on antiretroviral therapy: implication for tuberculosis preventive therapy.

Karo B, Krause G, Castell S, Kollan C, Hamouda O, Haas W; ClinSurv HIV Study Group.

BMC Infect Dis. 2017 Jul 25;17(1):517. doi: 10.1186/s12879-017-2627-y.


Establishing an ICD-10 code based SARI-surveillance in Germany - description of the system and first results from five recent influenza seasons.

Buda S, Tolksdorf K, Schuler E, Kuhlen R, Haas W.

BMC Public Health. 2017 Jun 30;17(1):612. doi: 10.1186/s12889-017-4515-1.


TERRA RNA Antagonizes ATRX and Protects Telomeres.

Chu HP, Cifuentes-Rojas C, Kesner B, Aeby E, Lee HG, Wei C, Oh HJ, Boukhali M, Haas W, Lee JT.

Cell. 2017 Jun 29;170(1):86-101.e16. doi: 10.1016/j.cell.2017.06.017.


Negative regulation of EGFR signalling by the human folliculin tumour suppressor protein.

Laviolette LA, Mermoud J, Calvo IA, Olson N, Boukhali M, Steinlein OK, Roider E, Sattler EC, Huang D, Teh BT, Motamedi M, Haas W, Iliopoulos O.

Nat Commun. 2017 Jun 28;8:15866. doi: 10.1038/ncomms15866.


[Tuberculosis Guideline for Adults - Guideline for Diagnosis and Treatment of Tuberculosis including LTBI Testing and Treatment of the German Central Committee (DZK) and the German Respiratory Society (DGP)].

Schaberg T, Bauer T, Brinkmann F, Diel R, Feiterna-Sperling C, Haas W, Hartmann P, Hauer B, Heyckendorf J, Lange C, Nienhaus A, Otto-Knapp R, Priwitzer M, Richter E, Rumetshofer R, Schenkel K, Schoch OD, Schönfeld N, Stahlmann R.

Pneumologie. 2017 Jun;71(6):325-397. doi: 10.1055/s-0043-105954. Epub 2017 Jun 26. German.


Contact investigation after a fatal case of extensively drug-resistant tuberculosis (XDR-TB) in an aircraft, Germany, July 2013.

An der Heiden M, Hauer B, Fiebig L, Glaser-Paschke G, Stemmler M, Simon C, Rüsch-Gerdes S, Gilsdorf A, Haas W.

Euro Surveill. 2017 Mar 23;22(12). pii: 30493. doi: 10.2807/1560-7917.ES.2017.22.12.30493.


Anti-Inflammatory Diet in Clinical Practice: A Review.

Ricker MA, Haas WC.

Nutr Clin Pract. 2017 Jun;32(3):318-325. doi: 10.1177/0884533617700353. Epub 2017 Mar 28. Review.


Cogenerating Synthetic Parts toward a Self-Replicating System.

Li J, Haas W, Jackson K, Kuru E, Jewett MC, Fan ZH, Gygi S, Church GM.

ACS Synth Biol. 2017 Jul 21;6(7):1327-1336. doi: 10.1021/acssynbio.6b00342. Epub 2017 Mar 29.


Treatment outcome in children with nontuberculous mycobacterial lymphadenitis: A retrospective follow-up study.

Reuss A, Drzymala S, Hauer B, von Kries R, Haas W.

Int J Mycobacteriol. 2017 Jan-Mar;6(1):76-82. doi: 10.4103/2212-5531.201898.


Expression of β-globin by cancer cells promotes cell survival during blood-borne dissemination.

Zheng Y, Miyamoto DT, Wittner BS, Sullivan JP, Aceto N, Jordan NV, Yu M, Karabacak NM, Comaills V, Morris R, Desai R, Desai N, Emmons E, Milner JD, Lee RJ, Wu CL, Sequist LV, Haas W, Ting DT, Toner M, Ramaswamy S, Maheswaran S, Haber DA.

Nat Commun. 2017 Feb 9;8:14344. doi: 10.1038/ncomms14344.


Global socioeconomic material stocks rise 23-fold over the 20th century and require half of annual resource use.

Krausmann F, Wiedenhofer D, Lauk C, Haas W, Tanikawa H, Fishman T, Miatto A, Schandl H, Haberl H.

Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):1880-1885. doi: 10.1073/pnas.1613773114. Epub 2017 Feb 6.


A joint cross-border investigation of a cluster of multidrug-resistant tuberculosis in Austria, Romania and Germany in 2014 using classic, genotyping and whole genome sequencing methods: lessons learnt.

Fiebig L, Kohl TA, Popovici O, Mühlenfeld M, Indra A, Homorodean D, Chiotan D, Richter E, Rüsch-Gerdes S, Schmidgruber B, Beckert P, Hauer B, Niemann S, Allerberger F, Haas W.

Euro Surveill. 2017 Jan 12;22(2). pii: 30439. doi: 10.2807/1560-7917.ES.2017.22.2.30439.


Coupling of Homologous Recombination and the Checkpoint by ATR.

Buisson R, Niraj J, Rodrigue A, Ho CK, Kreuzer J, Foo TK, Hardy EJ, Dellaire G, Haas W, Xia B, Masson JY, Zou L.

Mol Cell. 2017 Jan 19;65(2):336-346. doi: 10.1016/j.molcel.2016.12.007. Epub 2017 Jan 12.


Permanent human occupation of the central Tibetan Plateau in the early Holocene.

Meyer MC, Aldenderfer MS, Wang Z, Hoffmann DL, Dahl JA, Degering D, Haas WR, Schlütz F.

Science. 2017 Jan 6;355(6320):64-67. doi: 10.1126/science.aag0357.


Interaction of p190A RhoGAP with eIF3A and Other Translation Preinitiation Factors Suggests a Role in Protein Biosynthesis.

Parasuraman P, Mulligan P, Walker JA, Li B, Boukhali M, Haas W, Bernards A.

J Biol Chem. 2017 Feb 17;292(7):2679-2689. doi: 10.1074/jbc.M116.769216. Epub 2016 Dec 22.


Tribbles ortholog NIPI-3 and bZIP transcription factor CEBP-1 regulate a Caenorhabditis elegans intestinal immune surveillance pathway.

McEwan DL, Feinbaum RL, Stroustrup N, Haas W, Conery AL, Anselmo A, Sadreyev R, Ausubel FM.

BMC Biol. 2016 Dec 7;14(1):105.


Genomic Instability Is Induced by Persistent Proliferation of Cells Undergoing Epithelial-to-Mesenchymal Transition.

Comaills V, Kabeche L, Morris R, Buisson R, Yu M, Madden MW, LiCausi JA, Boukhali M, Tajima K, Pan S, Aceto N, Sil S, Zheng Y, Sundaresan T, Yae T, Jordan NV, Miyamoto DT, Ting DT, Ramaswamy S, Haas W, Zou L, Haber DA, Maheswaran S.

Cell Rep. 2016 Dec 6;17(10):2632-2647. doi: 10.1016/j.celrep.2016.11.022.


LKB1 loss links serine metabolism to DNA methylation and tumorigenesis.

Kottakis F, Nicolay BN, Roumane A, Karnik R, Gu H, Nagle JM, Boukhali M, Hayward MC, Li YY, Chen T, Liesa M, Hammerman PS, Wong KK, Hayes DN, Shirihai OS, Dyson NJ, Haas W, Meissner A, Bardeesy N.

Nature. 2016 Nov 17;539(7629):390-395. doi: 10.1038/nature20132. Epub 2016 Oct 31.


[Evaluation of an ICD-10-based electronic surveillance of acute respiratory infections (SEEDARI) in Germany].

Köpke K, Prahm K, Buda S, Haas W.

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2016 Nov;59(11):1484-1491. German.


[Influenza and community acquired pneumonia in German primary care].

Zanuzdana A, Köpke K, Haas W.

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2016 Nov;59(11):1492-1502. German.


PHD3 Loss in Cancer Enables Metabolic Reliance on Fatty Acid Oxidation via Deactivation of ACC2.

German NJ, Yoon H, Yusuf RZ, Murphy JP, Finley LW, Laurent G, Haas W, Satterstrom FK, Guarnerio J, Zaganjor E, Santos D, Pandolfi PP, Beck AH, Gygi SP, Scadden DT, Kaelin WG Jr, Haigis MC.

Mol Cell. 2016 Sep 15;63(6):1006-20. doi: 10.1016/j.molcel.2016.08.014.


European Neolithic societies showed early warning signals of population collapse.

Downey SS, Haas WR Jr, Shennan SJ.

Proc Natl Acad Sci U S A. 2016 Aug 30;113(35):9751-6. doi: 10.1073/pnas.1602504113.


HER2 expression identifies dynamic functional states within circulating breast cancer cells.

Jordan NV, Bardia A, Wittner BS, Benes C, Ligorio M, Zheng Y, Yu M, Sundaresan TK, Licausi JA, Desai R, O'Keefe RM, Ebright RY, Boukhali M, Sil S, Onozato ML, Iafrate AJ, Kapur R, Sgroi D, Ting DT, Toner M, Ramaswamy S, Haas W, Maheswaran S, Haber DA.

Nature. 2016 Sep 1;537(7618):102-106. doi: 10.1038/nature19328. Epub 2016 Aug 24.


Maintenance and Expansion: Modeling Material Stocks and Flows for Residential Buildings and Transportation Networks in the EU25.

Wiedenhofer D, Steinberger JK, Eisenmenger N, Haas W.

J Ind Ecol. 2015 Aug;19(4):538-551. Epub 2015 Jan 15.


Red meat, diseases, and healthy alternatives: A critical review.

Ekmekcioglu C, Wallner P, Kundi M, Weisz U, Haas W, Hutter HP.

Crit Rev Food Sci Nutr. 2018 Jan 22;58(2):247-261. doi: 10.1080/10408398.2016.1158148. Epub 2017 Jun 28.


Recommendations of the German Central Committee against Tuberculosis (DZK) and the German Respiratory Society (DGP) for the Diagnosis and Treatment of Non-tuberculous Mycobacterioses.

Schoenfeld N, Haas W, Richter E, Bauer T, Boes L, Castell S, Hauer B, Magdorf K, Matthiessen W, Mauch H, Reuss A, Schenkel K, Ruesch-Gerdes S, Zabel P, Dalhoff K, Schaberg T, Loddenkemper R.

Pneumologie. 2016 Apr;70(4):250-76. doi: 10.1055/s-0041-111494. Epub 2016 Apr 11. Review.


[Influenza pandemic deaths in Germany from 1918 to 2009. Estimates based on literature and own calculations].

Buchholz U, Buda S, Reuß A, Haas W, Uphoff H.

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2016 Apr;59(4):523-36. doi: 10.1007/s00103-016-2324-9. Review. German.


Fungal Infections in Boston Keratoprosthesis Patients: Lessons Learned and Novel Developments on the Horizon.

Odorcic S, Sabeti S, Haas W, Durand ML, Dohlman CH.

Semin Ophthalmol. 2016;31(1-2):71-84. doi: 10.3109/08820538.2015.1114871. Review.


A Specialized Mechanism of Translation Mediated by FXR1a-Associated MicroRNP in Cellular Quiescence.

Bukhari SIA, Truesdell SS, Lee S, Kollu S, Classon A, Boukhali M, Jain E, Mortensen RD, Yanagiya A, Sadreyev RI, Haas W, Vasudevan S.

Mol Cell. 2016 Mar 3;61(5):760-773. doi: 10.1016/j.molcel.2016.02.013.


Impact of HIV infection on treatment outcome of tuberculosis in Europe.

Karo B, Krause G, Hollo V, van der Werf MJ, Castell S, Hamouda O, Haas W.

AIDS. 2016 Apr 24;30(7):1089-98. doi: 10.1097/QAD.0000000000001016.


Multiplexed Quantitative Proteomics for High-Throughput Comprehensive Proteome Comparisons of Human Cell Lines.

Edwards A, Haas W.

Methods Mol Biol. 2016;1394:1-13. doi: 10.1007/978-1-4939-3341-9_1.


Tuberculosis treatment outcome in the European Union and European Economic Area: an analysis of surveillance data from 2002-2011.

Karo B, Hauer B, Hollo V, van der Werf MJ, Fiebig L, Haas W.

Euro Surveill. 2015;20(49). doi: 10.2807/1560-7917.ES.2015.20.49.30087. Erratum in: Euro Surveill. 2015;20(50). doi: 10.2807/1560-7917.ES.2015.20.50.30092.


AKT Inhibition Promotes Nonautonomous Cancer Cell Survival.

Salony, Solé X, Alves CP, Dey-Guha I, Ritsma L, Boukhali M, Lee JH, Chowdhury J, Ross KN, Haas W, Vasudevan S, Ramaswamy S.

Mol Cancer Ther. 2016 Jan;15(1):142-53. doi: 10.1158/1535-7163.MCT-15-0414. Epub 2015 Dec 4.

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