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Items: 25

1.

Hepatic PPARα is critical in the metabolic adaptation to sepsis.

Paumelle R, Haas JT, Hennuyer N, Baugé E, Deleye Y, Mesotten D, Langouche L, Vanhoutte J, Cudejko C, Wouters K, Hannou SA, Legry V, Lancel S, Lalloyer F, Polizzi A, Smati S, Gourdy P, Vallez E, Bouchaert E, Derudas B, Dehondt H, Gheeraert C, Fleury S, Tailleux A, Montagner A, Wahli W, Van Den Berghe G, Guillou H, Dombrowicz D, Staels B.

J Hepatol. 2019 Jan 21. pii: S0168-8278(19)30027-3. doi: 10.1016/j.jhep.2018.12.037. [Epub ahead of print]

PMID:
30677458
2.

Nuclear Receptor Subfamily 1 Group D Member 1 Regulates Circadian Activity of NLRP3 Inflammasome to Reduce the Severity of Fulminant Hepatitis in Mice.

Pourcet B, Zecchin M, Ferri L, Beauchamp J, Sitaula S, Billon C, Delhaye S, Vanhoutte J, Mayeuf-Louchart A, Thorel Q, Haas JT, Eeckhoute J, Dombrowicz D, Duhem C, Boulinguiez A, Lancel S, Sebti Y, Burris TP, Staels B, Duez HM.

Gastroenterology. 2018 Apr;154(5):1449-1464.e20. doi: 10.1053/j.gastro.2017.12.019. Epub 2017 Dec 24.

3.

Fasting the Microbiota to Improve Metabolism?

Haas JT, Staels B.

Cell Metab. 2017 Oct 3;26(4):584-585. doi: 10.1016/j.cmet.2017.09.013.

4.

Bile Acid Alterations Are Associated With Insulin Resistance, but Not With NASH, in Obese Subjects.

Legry V, Francque S, Haas JT, Verrijken A, Caron S, Chávez-Talavera O, Vallez E, Vonghia L, Dirinck E, Verhaegen A, Kouach M, Lestavel S, Lefebvre P, Van Gaal L, Tailleux A, Paumelle R, Staels B.

J Clin Endocrinol Metab. 2017 Oct 1;102(10):3783-3794. doi: 10.1210/jc.2017-01397.

PMID:
28938455
5.

Triglyceride Synthesis by DGAT1 Protects Adipocytes from Lipid-Induced ER Stress during Lipolysis.

Chitraju C, Mejhert N, Haas JT, Diaz-Ramirez LG, Grueter CA, Imbriglio JE, Pinto S, Koliwad SK, Walther TC, Farese RV Jr.

Cell Metab. 2017 Aug 1;26(2):407-418.e3. doi: 10.1016/j.cmet.2017.07.012.

6.

An oxidative stress paradox: time for a conceptual change?

Haas JT, Staels B.

Diabetologia. 2016 Dec;59(12):2514-2517. Epub 2016 Oct 1.

PMID:
27695900
7.

Pathophysiology and Mechanisms of Nonalcoholic Fatty Liver Disease.

Haas JT, Francque S, Staels B.

Annu Rev Physiol. 2016;78:181-205. doi: 10.1146/annurev-physiol-021115-105331. Epub 2015 Nov 30. Review.

PMID:
26667070
8.

Cholesteryl-ester transfer protein (CETP): A Kupffer cell marker linking hepatic inflammation with atherogenic dyslipidemia?

Haas JT, Staels B.

Hepatology. 2015 Dec;62(6):1659-61. doi: 10.1002/hep.28125. Epub 2015 Oct 24. No abstract available.

PMID:
26282884
9.

Chlamydia trachomatis Infection Leads to Defined Alterations to the Lipid Droplet Proteome in Epithelial Cells.

Saka HA, Thompson JW, Chen YS, Dubois LG, Haas JT, Moseley A, Valdivia RH.

PLoS One. 2015 Apr 24;10(4):e0124630. doi: 10.1371/journal.pone.0124630. eCollection 2015.

10.

Lipid droplet biogenesis.

Wilfling F, Haas JT, Walther TC, Farese RV Jr.

Curr Opin Cell Biol. 2014 Aug;29:39-45. doi: 10.1016/j.ceb.2014.03.008. Epub 2014 Apr 14. Review.

11.

Hepatic insulin receptor deficiency impairs the SREBP-2 response to feeding and statins.

Miao J, Haas JT, Manthena P, Wang Y, Zhao E, Vaitheesvaran B, Kurland IJ, Biddinger SB.

J Lipid Res. 2014 Apr;55(4):659-67. doi: 10.1194/jlr.M043711. Epub 2014 Feb 10.

12.

Patient outcome following 2 different stress imaging approaches: a prospective randomized comparison.

Porter TR, Smith LM, Wu J, Thomas D, Haas JT, Mathers DH, Williams E, Olson J, Nalty K, Hess R, Therrien S, Xie F.

J Am Coll Cardiol. 2013 Jun 18;61(24):2446-2455. doi: 10.1016/j.jacc.2013.04.019. Epub 2013 May 2.

13.

Diacylglycerol acyltransferase-1 localizes hepatitis C virus NS5A protein to lipid droplets and enhances NS5A interaction with the viral capsid core.

Camus G, Herker E, Modi AA, Haas JT, Ramage HR, Farese RV Jr, Ott M.

J Biol Chem. 2013 Apr 5;288(14):9915-23. doi: 10.1074/jbc.M112.434910. Epub 2013 Feb 18.

14.

Triacylglycerol synthesis enzymes mediate lipid droplet growth by relocalizing from the ER to lipid droplets.

Wilfling F, Wang H, Haas JT, Krahmer N, Gould TJ, Uchida A, Cheng JX, Graham M, Christiano R, Fröhlich F, Liu X, Buhman KK, Coleman RA, Bewersdorf J, Farese RV Jr, Walther TC.

Dev Cell. 2013 Feb 25;24(4):384-99. doi: 10.1016/j.devcel.2013.01.013. Epub 2013 Feb 14.

15.

DGAT1 mutation is linked to a congenital diarrheal disorder.

Haas JT, Winter HS, Lim E, Kirby A, Blumenstiel B, DeFelice M, Gabriel S, Jalas C, Branski D, Grueter CA, Toporovski MS, Walther TC, Daly MJ, Farese RV Jr.

J Clin Invest. 2012 Dec;122(12):4680-4. doi: 10.1172/JCI64873. Epub 2012 Nov 1.

16.

Studies on the substrate and stereo/regioselectivity of adipose triglyceride lipase, hormone-sensitive lipase, and diacylglycerol-O-acyltransferases.

Eichmann TO, Kumari M, Haas JT, Farese RV Jr, Zimmermann R, Lass A, Zechner R.

J Biol Chem. 2012 Nov 30;287(49):41446-57. doi: 10.1074/jbc.M112.400416. Epub 2012 Oct 12.

17.

The FATP1-DGAT2 complex facilitates lipid droplet expansion at the ER-lipid droplet interface.

Xu N, Zhang SO, Cole RA, McKinney SA, Guo F, Haas JT, Bobba S, Farese RV Jr, Mak HY.

J Cell Biol. 2012 Sep 3;198(5):895-911. doi: 10.1083/jcb.201201139. Epub 2012 Aug 27.

18.

Experimental study of the 4fn → 4fn and 4fn → 4fn-15d1 transitions of the lanthanide diiodides LnI2 (Ln=Nd, Sm, Eu, Dy, Tm, Yb).

Rogers E, Dorenbos P, de Haas JT, van der Kolk E.

J Phys Condens Matter. 2012 Jul 11;24(27):275502. doi: 10.1088/0953-8984/24/27/275502. Epub 2012 Jun 20.

PMID:
22713248
19.

Hepatic insulin signaling is required for obesity-dependent expression of SREBP-1c mRNA but not for feeding-dependent expression.

Haas JT, Miao J, Chanda D, Wang Y, Zhao E, Haas ME, Hirschey M, Vaitheesvaran B, Farese RV Jr, Kurland IJ, Graham M, Crooke R, Foufelle F, Biddinger SB.

Cell Metab. 2012 Jun 6;15(6):873-84. doi: 10.1016/j.cmet.2012.05.002.

20.

DGAT enzymes are required for triacylglycerol synthesis and lipid droplets in adipocytes.

Harris CA, Haas JT, Streeper RS, Stone SJ, Kumari M, Yang K, Han X, Brownell N, Gross RW, Zechner R, Farese RV Jr.

J Lipid Res. 2011 Apr;52(4):657-67. doi: 10.1194/jlr.M013003. Epub 2011 Feb 11.

21.

Transcriptional activation of apolipoprotein CIII expression by glucose may contribute to diabetic dyslipidemia.

Caron S, Verrijken A, Mertens I, Samanez CH, Mautino G, Haas JT, Duran-Sandoval D, Prawitt J, Francque S, Vallez E, Muhr-Tailleux A, Berard I, Kuipers F, Kuivenhoven JA, Biddinger SB, Taskinen MR, Van Gaal L, Staels B.

Arterioscler Thromb Vasc Biol. 2011 Mar;31(3):513-9. doi: 10.1161/ATVBAHA.110.220723. Epub 2010 Dec 23.

PMID:
21183731
22.

Dissecting the role of insulin resistance in the metabolic syndrome.

Haas JT, Biddinger SB.

Curr Opin Lipidol. 2009 Jun;20(3):206-10. doi: 10.1097/MOL.0b013e32832b2024. Review.

23.

Hepatic insulin resistance directly promotes formation of cholesterol gallstones.

Biddinger SB, Haas JT, Yu BB, Bezy O, Jing E, Zhang W, Unterman TG, Carey MC, Kahn CR.

Nat Med. 2008 Jul;14(7):778-82. doi: 10.1038/nm1785. Epub 2008 Jun 29.

24.

Hepatic insulin resistance is sufficient to produce dyslipidemia and susceptibility to atherosclerosis.

Biddinger SB, Hernandez-Ono A, Rask-Madsen C, Haas JT, Alemán JO, Suzuki R, Scapa EF, Agarwal C, Carey MC, Stephanopoulos G, Cohen DE, King GL, Ginsberg HN, Kahn CR.

Cell Metab. 2008 Feb;7(2):125-34. doi: 10.1016/j.cmet.2007.11.013.

25.

GMF-knockout mice are unable to induce brain-derived neurotrophic factor after exercise.

Zaheer A, Haas JT, Reyes C, Mathur SN, Yang B, Lim R.

Neurochem Res. 2006 Apr;31(4):579-84. Epub 2006 May 13.

PMID:
16758368

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