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Items: 1 to 50 of 78

1.

Alternative Biosynthetic Starter Units Enhance the Structural Diversity of Cyanobacterial Lipopeptides.

Mareš J, Hájek J, Urajová P, Kust A, Jokela J, Saurav K, Galica T, Čapková K, Mattila A, Haapaniemi E, Permi P, Mysterud I, Skulberg OM, Karlsen J, Fewer DP, Sivonen K, Tønnesen HH, Hrouzek P.

Appl Environ Microbiol. 2019 Feb 6;85(4). pii: e02675-18. doi: 10.1128/AEM.02675-18. Print 2019 Feb 15.

PMID:
30504214
2.

Return to work after ischemic stroke in young adults: A registry-based follow-up study.

Aarnio K, Rodríguez-Pardo J, Siegerink B, Hardt J, Broman J, Tulkki L, Haapaniemi E, Kaste M, Tatlisumak T, Putaala J.

Neurology. 2018 Nov 13;91(20):e1909-e1917. doi: 10.1212/WNL.0000000000006510. Epub 2018 Oct 12.

3.

CRISPR-Cas9 genome editing induces a p53-mediated DNA damage response.

Haapaniemi E, Botla S, Persson J, Schmierer B, Taipale J.

Nat Med. 2018 Jul;24(7):927-930. doi: 10.1038/s41591-018-0049-z. Epub 2018 Jun 11.

PMID:
29892067
4.

Novel LRBA Mutation and Possible Germinal Mosaicism in a Slavic Family.

Sharapova SO, Haapaniemi E, Sakovich IS, Rojas J, Gámez-Díaz L, Mareika YE, Guryanova IE, Migas AA, Mikhaleuskaya TM, Grimbacher B, Aleinikova OV.

J Clin Immunol. 2018 May;38(4):471-474. doi: 10.1007/s10875-018-0515-x. Epub 2018 May 26. No abstract available.

PMID:
29804237
5.

Discovery of a Pederin Family Compound in a Nonsymbiotic Bloom-Forming Cyanobacterium.

Kust A, Mareš J, Jokela J, Urajová P, Hájek J, Saurav K, Voráčová K, Fewer DP, Haapaniemi E, Permi P, Řeháková K, Sivonen K, Hrouzek P.

ACS Chem Biol. 2018 May 18;13(5):1123-1129. doi: 10.1021/acschembio.7b01048. Epub 2018 May 2.

PMID:
29570981
6.

Production of High Amounts of Hepatotoxin Nodularin and New Protease Inhibitors Pseudospumigins by the Brazilian Benthic Nostoc sp. CENA543.

Jokela J, Heinilä LMP, Shishido TK, Wahlsten M, Fewer DP, Fiore MF, Wang H, Haapaniemi E, Permi P, Sivonen K.

Front Microbiol. 2017 Oct 9;8:1963. doi: 10.3389/fmicb.2017.01963. eCollection 2017.

7.

Complete 1 H, 13 C{1 H}, and 31 P NMR spectral parameters of some pyrophosphates.

Haapaniemi E.

Magn Reson Chem. 2017 Sep;55(9):804-812. doi: 10.1002/mrc.4590. Epub 2017 Mar 21.

PMID:
28225171
8.

Damaging heterozygous mutations in NFKB1 lead to diverse immunologic phenotypes.

Kaustio M, Haapaniemi E, Göös H, Hautala T, Park G, Syrjänen J, Einarsdottir E, Sahu B, Kilpinen S, Rounioja S, Fogarty CL, Glumoff V, Kulmala P, Katayama S, Tamene F, Trotta L, Morgunova E, Krjutškov K, Nurmi K, Eklund K, Lagerstedt A, Helminen M, Martelius T, Mustjoki S, Taipale J, Saarela J, Kere J, Varjosalo M, Seppänen M.

J Allergy Clin Immunol. 2017 Sep;140(3):782-796. doi: 10.1016/j.jaci.2016.10.054. Epub 2017 Jan 21.

PMID:
28115215
9.

Combined immunodeficiency and hypoglycemia associated with mutations in hypoxia upregulated 1.

Haapaniemi EM, Fogarty CL, Keskitalo S, Katayama S, Vihinen H, Ilander M, Mustjoki S, Krjutškov K, Lehto M, Hautala T, Eriksson O, Jokitalo E, Velagapudi V, Varjosalo M, Seppänen M, Kere J.

J Allergy Clin Immunol. 2017 Apr;139(4):1391-1393.e11. doi: 10.1016/j.jaci.2016.09.050. Epub 2016 Nov 29. No abstract available.

10.

Towards the genetic basis of cerebral venous thrombosis-the BEAST Consortium: a study protocol.

Cotlarciuc I, Marjot T, Khan MS, Hiltunen S, Haapaniemi E, Metso TM, Putaala J, Zuurbier SM, Brouwer MC, Passamonti SM, Bucciarelli P, Pappalardo E, Patel T, Costa P, Colombi M, Canhão P, Tkach A, Santacroce R, Margaglione M, Favuzzi G, Grandone E, Colaizzo D, Spengos K, Arauz A, Hodge A, Ditta R, Debette S, Zedde M, Pare G, Ferro JM, Thijs V, Pezzini A, Majersik JJ, Martinelli I, Coutinho JM, Tatlisumak T, Sharma P; ISGC (International Stroke Genetics Consortium) and BEAST investigators.

BMJ Open. 2016 Nov 22;6(11):e012351. doi: 10.1136/bmjopen-2016-012351.

11.

Are 12-lead ECG findings associated with the risk of cardiovascular events after ischemic stroke in young adults?

Pirinen J, Putaala J, Aarnio K, Aro AL, Sinisalo J, Kaste M, Haapaniemi E, Tatlisumak T, Lehto M.

Ann Med. 2016 Nov;48(7):532-540. Epub 2016 Sep 29.

PMID:
27684300
12.

Symptomatic post-thrombolytic intracerebral hemorrhage is not related to the cause of stroke.

Curtze S, Sibolt G, Melkas S, Mustanoja S, Haapaniemi E, Putaala J, Sairanen T, Tiainen M, Tatlisumak T, Strbian D.

Eur J Neurol. 2016 Dec;23(12):1700-1704. doi: 10.1111/ene.13128. Epub 2016 Sep 3.

PMID:
27591741
13.

Cerebral white matter lesions and post-thrombolytic remote parenchymal hemorrhage.

Curtze S, Putaala J, Sibolt G, Melkas S, Mustanoja S, Haapaniemi E, Sairanen T, Tiainen M, Tatlisumak T, Strbian D.

Ann Neurol. 2016 Oct;80(4):593-9. doi: 10.1002/ana.24760. Epub 2016 Aug 26.

PMID:
27531598
14.

Post-thrombolytic blood pressure and symptomatic intracerebral hemorrhage.

Waltimo T, Haapaniemi E, Surakka IL, Melkas S, Sairanen T, Sibolt G, Tatlisumak T, Strbian D.

Eur J Neurol. 2016 Dec;23(12):1757-1762. doi: 10.1111/ene.13118. Epub 2016 Aug 16.

PMID:
27529662
15.

Cardiovascular events after ischemic stroke in young adults: A prospective follow-up study.

Aarnio K, Siegerink B, Pirinen J, Sinisalo J, Lehto M, Haapaniemi E, Nave AH, Kaste M, Tatlisumak T, Putaala J.

Neurology. 2016 May 17;86(20):1872-9. doi: 10.1212/WNL.0000000000002689. Epub 2016 Apr 20.

PMID:
27164672
16.

Long-term outcome after cerebral venous thrombosis: analysis of functional and vocational outcome, residual symptoms, and adverse events in 161 patients.

Hiltunen S, Putaala J, Haapaniemi E, Tatlisumak T.

J Neurol. 2016 Mar;263(3):477-84. doi: 10.1007/s00415-015-7996-9. Epub 2016 Jan 2.

PMID:
26725090
17.

Admission Hyperglycemia and Clinical Outcome in Cerebral Venous Thrombosis.

Zuurbier SM, Hiltunen S, Tatlisumak T, Peters GM, Silvis SM, Haapaniemi E, Kruyt ND, Putaala J, Coutinho JM.

Stroke. 2016 Feb;47(2):390-6. doi: 10.1161/STROKEAHA.115.011177. Epub 2015 Dec 15.

PMID:
26670083
18.

Higher neutrophil counts before thrombolysis for cerebral ischemia predict worse outcomes.

Maestrini I, Strbian D, Gautier S, Haapaniemi E, Moulin S, Sairanen T, Dequatre-Ponchelle N, Sibolt G, Cordonnier C, Melkas S, Leys D, Tatlisumak T, Bordet R.

Neurology. 2015 Oct 20;85(16):1408-16. doi: 10.1212/WNL.0000000000002029. Epub 2015 Sep 11.

19.

Helsinki experience on nonvitamin K oral anticoagulants for treating cervical artery dissection.

Mustanoja S, Metso TM, Putaala J, Heikkinen N, Haapaniemi E, Salonen O, Tatlisumak T.

Brain Behav. 2015 Aug;5(8):e00349. doi: 10.1002/brb3.349. Epub 2015 May 30.

20.

Undetermined stroke with an embolic pattern--a common phenotype with high early recurrence risk.

Putaala J, Nieminen T, Haapaniemi E, Meretoja A, Rantanen K, Heikkinen N, Kinnunen J, Strbian D, Mustanoja S, Curtze S, Pakarinen S, Lehto M, Tatlisumak T.

Ann Med. 2015;47(5):406-13. doi: 10.3109/07853890.2015.1057612. Epub 2015 Aug 4.

PMID:
26224200
21.

Resting 12-lead electrocardiogram reveals high-risk sources of cardioembolism in young adult ischemic stroke.

Pirinen J, Putaala J, Aro AL, Surakka I, Haapaniemi A, Kaste M, Haapaniemi E, Tatlisumak T, Lehto M.

Int J Cardiol. 2015 Nov 1;198:196-200. doi: 10.1016/j.ijcard.2015.06.095. Epub 2015 Jun 29.

PMID:
26163917
22.

White Matter Lesions Double the Risk of Post-Thrombolytic Intracerebral Hemorrhage.

Curtze S, Haapaniemi E, Melkas S, Mustanoja S, Putaala J, Sairanen T, Sibolt G, Tiainen M, Tatlisumak T, Strbian D.

Stroke. 2015 Aug;46(8):2149-55. doi: 10.1161/STROKEAHA.115.009318. Epub 2015 Jun 25.

PMID:
26111888
23.

Inherited DOCK2 Deficiency in Patients with Early-Onset Invasive Infections.

Dobbs K, Domínguez Conde C, Zhang SY, Parolini S, Audry M, Chou J, Haapaniemi E, Keles S, Bilic I, Okada S, Massaad MJ, Rounioja S, Alwahadneh AM, Serwas NK, Capuder K, Çiftçi E, Felgentreff K, Ohsumi TK, Pedergnana V, Boisson B, Haskoloğlu Ş, Ensari A, Schuster M, Moretta A, Itan Y, Patrizi O, Rozenberg F, Lebon P, Saarela J, Knip M, Petrovski S, Goldstein DB, Parrott RE, Savas B, Schambach A, Tabellini G, Bock C, Chatila TA, Comeau AM, Geha RS, Abel L, Buckley RH, İkincioğulları A, Al-Herz W, Helminen M, Doğu F, Casanova JL, Boztuğ K, Notarangelo LD.

N Engl J Med. 2015 Jun 18;372(25):2409-22. doi: 10.1056/NEJMoa1413462.

24.

Cancer in young adults with ischemic stroke.

Aarnio K, Joensuu H, Haapaniemi E, Melkas S, Kaste M, Tatlisumak T, Putaala J.

Stroke. 2015 Jun;46(6):1601-6. doi: 10.1161/STROKEAHA.115.008694. Epub 2015 Apr 28.

PMID:
25922510
25.

Cerebral computed tomography-graded white matter lesions are associated with worse outcome after thrombolysis in patients with stroke.

Curtze S, Melkas S, Sibolt G, Haapaniemi E, Mustanoja S, Putaala J, Sairanen T, Tiainen M, Tatlisumak T, Strbian D.

Stroke. 2015 Jun;46(6):1554-60. doi: 10.1161/STROKEAHA.115.008941. Epub 2015 Apr 21.

PMID:
25899244
26.

Medical acute complications of intracerebral hemorrhage in young adults.

Koivunen RJ, Haapaniemi E, Satopää J, Niemelä M, Tatlisumak T, Putaala J.

Stroke Res Treat. 2015;2015:357696. doi: 10.1155/2015/357696. Epub 2015 Feb 2.

27.

Extent of secondary intraventricular hemorrhage is an independent predictor of outcomes in intracerebral hemorrhage: data from the Helsinki ICH Study.

Mustanoja S, Satopää J, Meretoja A, Putaala J, Strbian D, Curtze S, Haapaniemi E, Sairanen T, Niemelä M, Kaste M, Tatlisumak T.

Int J Stroke. 2015 Jun;10(4):576-81. doi: 10.1111/ijs.12437. Epub 2015 Jan 12.

PMID:
25580771
28.

Gut microbiota are related to Parkinson's disease and clinical phenotype.

Scheperjans F, Aho V, Pereira PA, Koskinen K, Paulin L, Pekkonen E, Haapaniemi E, Kaakkola S, Eerola-Rautio J, Pohja M, Kinnunen E, Murros K, Auvinen P.

Mov Disord. 2015 Mar;30(3):350-8. doi: 10.1002/mds.26069. Epub 2014 Dec 5.

PMID:
25476529
29.

Autoimmunity, hypogammaglobulinemia, lymphoproliferation, and mycobacterial disease in patients with activating mutations in STAT3.

Haapaniemi EM, Kaustio M, Rajala HL, van Adrichem AJ, Kainulainen L, Glumoff V, Doffinger R, Kuusanmäki H, Heiskanen-Kosma T, Trotta L, Chiang S, Kulmala P, Eldfors S, Katainen R, Siitonen S, Karjalainen-Lindsberg ML, Kovanen PE, Otonkoski T, Porkka K, Heiskanen K, Hänninen A, Bryceson YT, Uusitalo-Seppälä R, Saarela J, Seppänen M, Mustjoki S, Kere J.

Blood. 2015 Jan 22;125(4):639-48. doi: 10.1182/blood-2014-04-570101. Epub 2014 Oct 27.

30.

Incidence, risk factors, etiology, severity and short-term outcome of non-traumatic intracerebral hemorrhage in young adults.

Koivunen RJ, Satopää J, Meretoja A, Strbian D, Haapaniemi E, Niemelä M, Tatlisumak T, Putaala J.

Eur J Neurol. 2015 Jan;22(1):123-32. doi: 10.1111/ene.12543. Epub 2014 Aug 21.

PMID:
25142530
31.

Central poststroke pain in young ischemic stroke survivors in the Helsinki Young Stroke Registry.

Harno H, Haapaniemi E, Putaala J, Haanpää M, Mäkelä JP, Kalso E, Tatlisumak T.

Neurology. 2014 Sep 23;83(13):1147-54. doi: 10.1212/WNL.0000000000000818. Epub 2014 Aug 15.

PMID:
25128182
32.

Long-term mortality after first-ever and recurrent stroke in young adults.

Aarnio K, Haapaniemi E, Melkas S, Kaste M, Tatlisumak T, Putaala J.

Stroke. 2014 Sep;45(9):2670-6. doi: 10.1161/STROKEAHA.114.005648. Epub 2014 Jul 24.

PMID:
25061076
33.

Activating germline mutations in STAT3 cause early-onset multi-organ autoimmune disease.

Flanagan SE, Haapaniemi E, Russell MA, Caswell R, Allen HL, De Franco E, McDonald TJ, Rajala H, Ramelius A, Barton J, Heiskanen K, Heiskanen-Kosma T, Kajosaari M, Murphy NP, Milenkovic T, Seppänen M, Lernmark Å, Mustjoki S, Otonkoski T, Kere J, Morgan NG, Ellard S, Hattersley AT.

Nat Genet. 2014 Aug;46(8):812-814. doi: 10.1038/ng.3040. Epub 2014 Jul 20.

34.

Predictors of early mortality in young adults after intracerebral hemorrhage.

Koivunen RJ, Satopää J, Haapaniemi E, Strbian D, Meretoja A, Mustanoja S, Silvennoinen H, Salonen O, Niemelä M, Tatlisumak T, Putaala J.

Stroke. 2014 Aug;45(8):2454-6. doi: 10.1161/STROKEAHA.114.006020. Epub 2014 Jun 19.

PMID:
24947290
35.

The CAVE score for predicting late seizures after intracerebral hemorrhage.

Haapaniemi E, Strbian D, Rossi C, Putaala J, Sipi T, Mustanoja S, Sairanen T, Curtze S, Satopää J, Roivainen R, Kaste M, Cordonnier C, Tatlisumak T, Meretoja A.

Stroke. 2014 Jul;45(7):1971-6. doi: 10.1161/STROKEAHA.114.004686. Epub 2014 May 29.

PMID:
24876089
36.

Racial disparities in early mortality in 1,134 young patients with acute stroke.

Tsivgoulis G, Putaala J, Sharma VK, Balucani C, Martin-Schild S, Giannopoulos S, Batala L, Krogias C, Palazzo P, Bavarsad Shahripour R, Arvaniti C, Barlinn K, Strbian D, Haapaniemi E, Flamouridou M, Vadikolias K, Heliopoulos I, Voumvourakis K, Triantafyllou N, Azarpazhooh MR, Athanasiadis D, Kosmidou M, Katsanos AH, Vasdekis SN, Stefanis L, Stamboulis E, Piperidou C, Tatlisumak T, Alexandrov AV.

Neurol Sci. 2014 Jul;35(7):1041-9. doi: 10.1007/s10072-014-1640-9. Epub 2014 Jan 28. Erratum in: Neurol Sci. 2014 Jul;35(7):1051-2. Shahripour, Reza Bavarsad [corrected to Bavarsad Shahripour, Reza].

PMID:
24469348
37.

Higher baseline international normalized ratio value correlates with higher mortality in intracerebral hemorrhage during warfarin use.

Curtze S, Strbian D, Meretoja A, Putaala J, Eriksson H, Haapaniemi E, Mustanoja S, Sairanen T, Satopää J, Silvennoinen H, Niemelä M, Kaste M, Tatlisumak T.

Eur J Neurol. 2014 Apr;21(4):616-22. doi: 10.1111/ene.12352. Epub 2014 Jan 21.

PMID:
24447727
38.

Preceding and poststroke infections in young adults with first-ever ischemic stroke: effect on short-term and long-term outcomes.

Heikinheimo T, Broman J, Haapaniemi E, Kaste M, Tatlisumak T, Putaala J.

Stroke. 2013 Dec;44(12):3331-7. doi: 10.1161/STROKEAHA.113.002108. Epub 2013 Oct 17.

PMID:
24135931
39.

IV thrombolysis and renal function.

Gensicke H, Zinkstok SM, Roos YB, Seiffge DJ, Ringleb P, Artto V, Putaala J, Haapaniemi E, Leys D, Bordet R, Michel P, Odier C, Berrouschot J, Arnold M, Heldner MR, Zini A, Bigliardi G, Padjen V, Peters N, Pezzini A, Schindler C, Sarikaya H, Bonati LH, Tatlisumak T, Lyrer PA, Nederkoorn PJ, Engelter ST.

Neurology. 2013 Nov 12;81(20):1780-8. doi: 10.1212/01.wnl.0000435550.83200.9e. Epub 2013 Oct 11.

40.

Etiology of first-ever ischaemic stroke in European young adults: the 15 cities young stroke study.

Yesilot Barlas N, Putaala J, Waje-Andreassen U, Vassilopoulou S, Nardi K, Odier C, Hofgart G, Engelter S, Burow A, Mihalka L, Kloss M, Ferrari J, Lemmens R, Coban O, Haapaniemi E, Maaijwee N, Rutten-Jacobs L, Bersano A, Cereda C, Baron P, Borellini L, Valcarenghi C, Thomassen L, Grau AJ, Palm F, Urbanek C, Tuncay R, Durukan Tolvanen A, van Dijk EJ, de Leeuw FE, Thijs V, Greisenegger S, Vemmos K, Lichy C, Bereczki D, Csiba L, Michel P, Leys D, Spengos K, Naess H, Tatlisumak T, Bahar SZ.

Eur J Neurol. 2013 Nov;20(11):1431-9. doi: 10.1111/ene.12228. Epub 2013 Jul 10.

PMID:
23837733
41.

Association of prestroke statin use and lipid levels with outcome of intracerebral hemorrhage.

Mustanoja S, Strbian D, Putaala J, Meretoja A, Curtze S, Haapaniemi E, Sairanen T, Hietikko R, Sirén J, Kaste M, Tatlisumak T.

Stroke. 2013 Aug;44(8):2330-2. doi: 10.1161/STROKEAHA.113.001829. Epub 2013 Jun 11.

PMID:
23760210
42.

Young adult ischaemic stroke related acute symptomatic and late seizures: risk factors.

Roivainen R, Haapaniemi E, Putaala J, Kaste M, Tatlisumak T.

Eur J Neurol. 2013 Sep;20(9):1247-55. doi: 10.1111/ene.12157. Epub 2013 Apr 14.

PMID:
23581284
43.

Safety of thrombolysis in stroke mimics: results from a multicenter cohort study.

Zinkstok SM, Engelter ST, Gensicke H, Lyrer PA, Ringleb PA, Artto V, Putaala J, Haapaniemi E, Tatlisumak T, Chen Y, Leys D, Sarikaya H, Michel P, Odier C, Berrouschot J, Arnold M, Heldner MR, Zini A, Fioravanti V, Padjen V, Beslac-Bumbasirevic L, Pezzini A, Roos YB, Nederkoorn PJ.

Stroke. 2013 Apr;44(4):1080-4. doi: 10.1161/STROKEAHA.111.000126. Epub 2013 Feb 26.

PMID:
23444310
44.

D-dimer and clinicoradiologic features in cerebral venous thrombosis.

Hiltunen S, Putaala J, Haapaniemi E, Salonen O, Tatlisumak T.

J Neurol Sci. 2013 Apr 15;327(1-2):12-4. doi: 10.1016/j.jns.2013.01.033. Epub 2013 Feb 20.

PMID:
23434247
45.

Leucocyte count in young adults with first-ever ischaemic stroke: associated factors and association on prognosis.

Heikinheimo T, Putaala J, Haapaniemi E, Kaste M, Tatlisumak T.

Int J Stroke. 2015 Feb;10(2):245-50. doi: 10.1111/j.1747-4949.2012.00968.x. Epub 2013 Jan 7.

PMID:
23295074
46.

Substituent effect in 2-benzoylmethylenequinoline difluoroborates exhibiting through-space couplings. Multinuclear magnetic resonance, X-ray diffraction, and computational study.

Zakrzewska A, Kolehmainen E, Valkonen A, Haapaniemi E, Rissanen K, Chęcińska L, Ośmiałowski B.

J Phys Chem A. 2013 Jan 10;117(1):252-6. doi: 10.1021/jp311072q. Epub 2012 Dec 31.

PMID:
23252343
47.

Multiple brain infarcts in young adults: clues for etiologic diagnosis and prognostic impact.

Mustanoja S, Putaala J, Haapaniemi E, Strbian D, Kaste M, Tatlisumak T.

Eur J Neurol. 2013 Feb;20(2):216-22. doi: 10.1111/j.1468-1331.2012.03872.x. Epub 2012 Oct 11.

PMID:
23057601
48.

2-Acylamino- and 2,4-bis(acylamino)pyrimidines as supramolecular synthons analyzed by multiple noncovalent interactions. DFT, X-ray diffraction, and NMR spectral studies.

Ośmiałowski B, Kolehmainen E, Ikonen S, Valkonen A, Kwiatkowski A, Grela I, Haapaniemi E.

J Org Chem. 2012 Nov 2;77(21):9609-19. doi: 10.1021/jo301643z. Epub 2012 Oct 11.

PMID:
23020688
49.

Intravenous alteplase versus rescue endovascular procedure in patients with proximal middle cerebral artery occlusion.

Strbian D, Mustanoja S, Pekkola J, Putaala J, Haapaniemi E, Paananen T, Kaste M, Lappalainen K, Tatlisumak T.

Int J Stroke. 2015 Feb;10(2):188-93. doi: 10.1111/j.1747-4949.2012.00918.x. Epub 2012 Sep 27.

PMID:
23013407
50.

Haemorrhagic transformation of ischaemic stroke in young adults.

Mustanoja S, Haapaniemi E, Putaala J, Strbian D, Kaste M, Tatlisumak T.

Int J Stroke. 2014 Oct;9 Suppl A100:85-92. doi: 10.1111/j.1747-4949.2012.00904.x. Epub 2012 Sep 27.

PMID:
23013222

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