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Items: 1 to 50 of 238

1.

Influenza A Virus Hemagglutinin-Neuraminidase-Receptor Balance: Preserving Virus Motility.

de Vries E, Du W, Guo H, de Haan CAM.

Trends Microbiol. 2019 Oct 16. pii: S0966-842X(19)30235-5. doi: 10.1016/j.tim.2019.08.010. [Epub ahead of print] Review.

PMID:
31629602
2.

Enhanced Inhibition of Influenza A Virus Adhesion by Di- and Trivalent Hemagglutinin Inhibitors.

Lu W, Du W, Somovilla VJ, Yu G, Haksar D, de Vries E, Boons GJ, de Vries RP, de Haan CAM, Pieters RJ.

J Med Chem. 2019 Jul 11;62(13):6398-6404. doi: 10.1021/acs.jmedchem.9b00303. Epub 2019 Jun 28.

3.

The 2nd sialic acid-binding site of influenza A virus neuraminidase is an important determinant of the hemagglutinin-neuraminidase-receptor balance.

Du W, Guo H, Nijman VS, Doedt J, van der Vries E, van der Lee J, Li Z, Boons GJ, van Kuppeveld FJM, de Vries E, Matrosovich M, de Haan CAM.

PLoS Pathog. 2019 Jun 10;15(6):e1007860. doi: 10.1371/journal.ppat.1007860. eCollection 2019 Jun.

4.

Modulation of the IL-6-Signaling Pathway in Liver Cells by miRNAs Targeting gp130, JAK1, and/or STAT3.

Servais FA, Kirchmeyer M, Hamdorf M, Minoungou NWE, Rose-John S, Kreis S, Haan C, Behrmann I.

Mol Ther Nucleic Acids. 2019 Jun 7;16:419-433. doi: 10.1016/j.omtn.2019.03.007. Epub 2019 Apr 2.

5.

Development and Standardization of a High-Throughput Multiplex Immunoassay for the Simultaneous Quantification of Specific Antibodies to Five Respiratory Syncytial Virus Proteins.

Schepp RM, de Haan CAM, Wilkins D, Layman H, Graham BS, Esser MT, Berbers GAM.

mSphere. 2019 Apr 24;4(2). pii: e00236-19. doi: 10.1128/mSphere.00236-19.

6.

Many ways to resistance: How melanoma cells evade targeted therapies.

Kozar I, Margue C, Rothengatter S, Haan C, Kreis S.

Biochim Biophys Acta Rev Cancer. 2019 Apr;1871(2):313-322. doi: 10.1016/j.bbcan.2019.02.002. Epub 2019 Feb 15. Review.

7.

Kinase inhibitor library screening identifies synergistic drug combinations effective in sensitive and resistant melanoma cells.

Margue C, Philippidou D, Kozar I, Cesi G, Felten P, Kulms D, Letellier E, Haan C, Kreis S.

J Exp Clin Cancer Res. 2019 Feb 6;38(1):56. doi: 10.1186/s13046-019-1038-x.

8.

Cross-Protective Immune Responses Induced by Sequential Influenza Virus Infection and by Sequential Vaccination With Inactivated Influenza Vaccines.

Dong W, Bhide Y, Sicca F, Meijerhof T, Guilfoyle K, Engelhardt OG, Boon L, de Haan CAM, Carnell G, Temperton N, de Vries-Idema J, Kelvin D, Huckriede A.

Front Immunol. 2018 Oct 9;9:2312. doi: 10.3389/fimmu.2018.02312. eCollection 2018.

9.

Passive inhalation of dry powder influenza vaccine formulations completely protects chickens against H5N1 lethal viral challenge.

Tomar J, Biel C, de Haan CAM, Rottier PJM, Petrovsky N, Frijlink HW, Huckriede A, Hinrichs WLJ, Peeters B.

Eur J Pharm Biopharm. 2018 Dec;133:85-95. doi: 10.1016/j.ejpb.2018.10.008. Epub 2018 Oct 9.

10.

A new ALK isoform transported by extracellular vesicles confers drug resistance to melanoma cells.

Cesi G, Philippidou D, Kozar I, Kim YJ, Bernardin F, Van Niel G, Wienecke-Baldacchino A, Felten P, Letellier E, Dengler S, Nashan D, Haan C, Kreis S.

Mol Cancer. 2018 Oct 5;17(1):145. doi: 10.1186/s12943-018-0886-x.

11.

Breast Milk Prefusion F Immunoglobulin G as a Correlate of Protection Against Respiratory Syncytial Virus Acute Respiratory Illness.

Mazur NI, Horsley NM, Englund JA, Nederend M, Magaret A, Kumar A, Jacobino SR, de Haan CAM, Khatry SK, LeClerq SC, Steinhoff MC, Tielsch JM, Katz J, Graham BS, Bont LJ, Leusen JHW, Chu HY.

J Infect Dis. 2019 Jan 1;219(1):59-67. doi: 10.1093/infdis/jiy477.

12.

Kinetic analysis of the influenza A virus HA/NA balance reveals contribution of NA to virus-receptor binding and NA-dependent rolling on receptor-containing surfaces.

Guo H, Rabouw H, Slomp A, Dai M, van der Vegt F, van Lent JWM, McBride R, Paulson JC, de Groot RJ, van Kuppeveld FJM, de Vries E, de Haan CAM.

PLoS Pathog. 2018 Aug 13;14(8):e1007233. doi: 10.1371/journal.ppat.1007233. eCollection 2018 Aug.

13.

Substrate Binding by the Second Sialic Acid-Binding Site of Influenza A Virus N1 Neuraminidase Contributes to Enzymatic Activity.

Du W, Dai M, Li Z, Boons GJ, Peeters B, van Kuppeveld FJM, de Vries E, de Haan CAM.

J Virol. 2018 Sep 26;92(20). pii: e01243-18. doi: 10.1128/JVI.01243-18. Print 2018 Oct 15.

14.

The PD-L1- and IL6-mediated dampening of the IL27/STAT1 anticancer responses are prevented by α-PD-L1 or α-IL6 antibodies.

Rolvering C, Zimmer AD, Ginolhac A, Margue C, Kirchmeyer M, Servais F, Hermanns HM, Hergovits S, Nazarov PV, Nicot N, Kreis S, Haan S, Behrmann I, Haan C.

J Leukoc Biol. 2018 Nov;104(5):969-985. doi: 10.1002/JLB.MA1217-495R. Epub 2018 Jul 24.

PMID:
30040142
15.

Role of enhanced receptor engagement in the evolution of a pandemic acute hemorrhagic conjunctivitis virus.

Baggen J, Hurdiss DL, Zocher G, Mistry N, Roberts RW, Slager JJ, Guo H, van Vliet ALW, Wahedi M, Benschop K, Duizer E, de Haan CAM, de Vries E, Casasnovas JM, de Groot RJ, Arnberg N, Stehle T, Ranson NA, Thibaut HJ, van Kuppeveld FJM.

Proc Natl Acad Sci U S A. 2018 Jan 9;115(2):397-402. doi: 10.1073/pnas.1713284115. Epub 2017 Dec 28.

16.

Antibodies Directed toward Neuraminidase N1 Control Disease in a Mouse Model of Influenza.

Job ER, Schotsaert M, Ibañez LI, Smet A, Ysenbaert T, Roose K, Dai M, de Haan CAM, Kleanthous H, Vogel TU, Saelens X.

J Virol. 2018 Jan 30;92(4). pii: e01584-17. doi: 10.1128/JVI.01584-17. Print 2018 Feb 15.

17.

Identification of sialic acid-binding function for the Middle East respiratory syndrome coronavirus spike glycoprotein.

Li W, Hulswit RJG, Widjaja I, Raj VS, McBride R, Peng W, Widagdo W, Tortorici MA, van Dieren B, Lang Y, van Lent JWM, Paulson JC, de Haan CAM, de Groot RJ, van Kuppeveld FJM, Haagmans BL, Bosch BJ.

Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):E8508-E8517. doi: 10.1073/pnas.1712592114. Epub 2017 Sep 18.

18.

In Vitro Enhancement of Respiratory Syncytial Virus Infection by Maternal Antibodies Does Not Explain Disease Severity in Infants.

van Erp EA, van Kasteren PB, Guichelaar T, Ahout IML, de Haan CAM, Luytjes W, Ferwerda G, Wicht O.

J Virol. 2017 Oct 13;91(21). pii: e00851-17. doi: 10.1128/JVI.00851-17. Print 2017 Nov 1.

19.

Coronavirus nucleocapsid proteins assemble constitutively in high molecular oligomers.

Cong Y, Kriegenburg F, de Haan CAM, Reggiori F.

Sci Rep. 2017 Jul 18;7(1):5740. doi: 10.1038/s41598-017-06062-w.

20.

Three mutations switch H7N9 influenza to human-type receptor specificity.

de Vries RP, Peng W, Grant OC, Thompson AJ, Zhu X, Bouwman KM, de la Pena ATT, van Breemen MJ, Ambepitiya Wickramasinghe IN, de Haan CAM, Yu W, McBride R, Sanders RW, Woods RJ, Verheije MH, Wilson IA, Paulson JC.

PLoS Pathog. 2017 Jun 15;13(6):e1006390. doi: 10.1371/journal.ppat.1006390. eCollection 2017 Jun.

21.

ROS production induced by BRAF inhibitor treatment rewires metabolic processes affecting cell growth of melanoma cells.

Cesi G, Walbrecq G, Zimmer A, Kreis S, Haan C.

Mol Cancer. 2017 Jun 8;16(1):102. doi: 10.1186/s12943-017-0667-y.

22.

Oncostatin M induces RIG-I and MDA5 expression and enhances the double-stranded RNA response in fibroblasts.

Hergovits S, Mais C, Haan C, Costa-Pereira AP, Hermanns HM.

J Cell Mol Med. 2017 Nov;21(11):3087-3099. doi: 10.1111/jcmm.13221. Epub 2017 May 30.

23.

The multi-site docking protein Gab1 is constitutively phosphorylated independent from its recruitment to the plasma membrane in Jak2-V617F-positive cells and mediates proliferation of human erythroleukaemia cells.

Bongartz H, Hessenkemper W, Müller C, Fensky M, Fritsch J, Mandel K, Behrmann I, Haan C, Fischer T, Feller SM, Schaper F.

Cell Signal. 2017 Jul;35:37-47. doi: 10.1016/j.cellsig.2017.03.021. Epub 2017 Mar 30.

PMID:
28365441
24.

Mutation of the Second Sialic Acid-Binding Site, Resulting in Reduced Neuraminidase Activity, Preceded the Emergence of H7N9 Influenza A Virus.

Dai M, McBride R, Dortmans JCFM, Peng W, Bakkers MJG, de Groot RJ, van Kuppeveld FJM, Paulson JC, de Vries E, de Haan CAM.

J Virol. 2017 Apr 13;91(9). pii: e00049-17. doi: 10.1128/JVI.00049-17. Print 2017 May 1.

25.

Genetic versus antigenic differences among highly pathogenic H5N1 avian influenza A viruses: Consequences for vaccine strain selection.

Peeters B, Reemers S, Dortmans J, de Vries E, de Jong M, van de Zande S, Rottier PJM, de Haan CAM.

Virology. 2017 Mar;503:83-93. doi: 10.1016/j.virol.2017.01.012. Epub 2017 Jan 28.

26.

Characteristics of RSV-Specific Maternal Antibodies in Plasma of Hospitalized, Acute RSV Patients under Three Months of Age.

Jans J, Wicht O, Widjaja I, Ahout IM, de Groot R, Guichelaar T, Luytjes W, de Jonge MI, de Haan CA, Ferwerda G.

PLoS One. 2017 Jan 30;12(1):e0170877. doi: 10.1371/journal.pone.0170877. eCollection 2017.

27.

Glycosylation Characterization of an Influenza H5N7 Hemagglutinin Series with Engineered Glycosylation Patterns: Implications for Structure-Function Relationships.

Parsons LM, An Y, de Vries RP, de Haan CA, Cipollo JF.

J Proteome Res. 2017 Feb 3;16(2):398-412. doi: 10.1021/acs.jproteome.6b00175. Epub 2016 Dec 5.

PMID:
28060516
28.

Crosstalk between different family members: IL27 recapitulates IFNγ responses in HCC cells, but is inhibited by IL6-type cytokines.

Rolvering C, Zimmer AD, Kozar I, Hermanns HM, Letellier E, Vallar L, Nazarov PV, Nicot N, Ginolhac A, Haan S, Behrmann I, Haan C.

Biochim Biophys Acta Mol Cell Res. 2017 Mar;1864(3):516-526. doi: 10.1016/j.bbamcr.2016.12.006. Epub 2016 Dec 9.

29.

Highly Pathogenic Influenza A(H5Nx) Viruses with Altered H5 Receptor-Binding Specificity.

Guo H, de Vries E, McBride R, Dekkers J, Peng W, Bouwman KM, Nycholat C, Verheije MH, Paulson JC, van Kuppeveld FJ, de Haan CA.

Emerg Infect Dis. 2017 Feb;23(2):220-231. doi: 10.3201/eid2302.161072. Epub 2017 Feb 15.

31.

Coronavirus Spike Protein and Tropism Changes.

Hulswit RJ, de Haan CA, Bosch BJ.

Adv Virus Res. 2016;96:29-57. doi: 10.1016/bs.aivir.2016.08.004. Epub 2016 Sep 13. Review.

PMID:
27712627
32.

An siRNA screen for ATG protein depletion reveals the extent of the unconventional functions of the autophagy proteome in virus replication.

Mauthe M, Langereis M, Jung J, Zhou X, Jones A, Omta W, Tooze SA, Stork B, Paludan SR, Ahola T, Egan D, Behrends C, Mokry M, de Haan C, van Kuppeveld F, Reggiori F.

J Cell Biol. 2016 Aug 29;214(5):619-35. doi: 10.1083/jcb.201602046.

33.

Identification of Residues That Affect Oligomerization and/or Enzymatic Activity of Influenza Virus H5N1 Neuraminidase Proteins.

Dai M, Guo H, Dortmans JC, Dekkers J, Nordholm J, Daniels R, van Kuppeveld FJ, de Vries E, de Haan CA.

J Virol. 2016 Sep 29;90(20):9457-70. doi: 10.1128/JVI.01346-16. Print 2016 Oct 15.

34.

RSV neutralization by palivizumab, but not by monoclonal antibodies targeting other epitopes, is augmented by Fc gamma receptors.

van Mechelen L, Luytjes W, de Haan CA, Wicht O.

Antiviral Res. 2016 Aug;132:1-5. doi: 10.1016/j.antiviral.2016.05.003. Epub 2016 May 13.

35.

Characterization of Epitope-Specific Anti-Respiratory Syncytial Virus (Anti-RSV) Antibody Responses after Natural Infection and after Vaccination with Formalin-Inactivated RSV.

Widjaja I, Wicht O, Luytjes W, Leenhouts K, Rottier PJM, van Kuppeveld FJM, Haijema BJ, de Haan CAM.

J Virol. 2016 Jun 10;90(13):5965-5977. doi: 10.1128/JVI.00235-16. Print 2016 Jul 1.

36.

The role of HIF-1 in oncostatin M-dependent metabolic reprogramming of hepatic cells.

Battello N, Zimmer AD, Goebel C, Dong X, Behrmann I, Haan C, Hiller K, Wegner A.

Cancer Metab. 2016 Feb 17;4:3. doi: 10.1186/s40170-016-0141-0. eCollection 2016.

37.

Enterovirus D68 receptor requirements unveiled by haploid genetics.

Baggen J, Thibaut HJ, Staring J, Jae LT, Liu Y, Guo H, Slager JJ, de Bruin JW, van Vliet AL, Blomen VA, Overduin P, Sheng J, de Haan CA, de Vries E, Meijer A, Rossmann MG, Brummelkamp TR, van Kuppeveld FJ.

Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):1399-404. doi: 10.1073/pnas.1524498113. Epub 2016 Jan 19. Erratum in: Proc Natl Acad Sci U S A. 2016 Mar 15;113(11):E1588. de Haan Xander, Cornelis A M [corrected to de Haan, Cornelis A M].

38.

The oncogenic FIP1L1-PDGFRα fusion protein displays skewed signaling properties compared to its wild-type PDGFRα counterpart.

Haan S, Bahlawane C, Wang J, Nazarov PV, Muller A, Eulenfeld R, Haan C, Rolvering C, Vallar L, Satagopam VP, Sauter T, Wiesinger MY.

JAKSTAT. 2015 Jul 17;4(1):e1062596. doi: 10.1080/21623996.2015.1062596. eCollection 2015.

39.

In silico structure-based design and synthesis of novel anti-RSV compounds.

Cancellieri M, Bassetto M, Widjaja I, van Kuppeveld F, de Haan CA, Brancale A.

Antiviral Res. 2015 Oct;122:46-50. doi: 10.1016/j.antiviral.2015.08.003. Epub 2015 Aug 8.

40.

Recombinant Soluble Respiratory Syncytial Virus F Protein That Lacks Heptad Repeat B, Contains a GCN4 Trimerization Motif and Is Not Cleaved Displays Prefusion-Like Characteristics.

Widjaja I, Rigter A, Jacobino S, van Kuppeveld FJ, Leenhouts K, Palomo C, Melero JA, Leusen JH, Haijema BJ, Rottier PJ, de Haan CA.

PLoS One. 2015 Jun 24;10(6):e0130829. doi: 10.1371/journal.pone.0130829. eCollection 2015.

41.

Host tissue and glycan binding specificities of avian viral attachment proteins using novel avian tissue microarrays.

Wickramasinghe IN, de Vries RP, Eggert AM, Wandee N, de Haan CA, Gröne A, Verheije MH.

PLoS One. 2015 Jun 2;10(6):e0128893. doi: 10.1371/journal.pone.0128893. eCollection 2015.

42.

Rapid Emergence of Highly Pathogenic Avian Influenza Subtypes from a Subtype H5N1 Hemagglutinin Variant.

de Vries E, Guo H, Dai M, Rottier PJ, van Kuppeveld FJ, de Haan CA.

Emerg Infect Dis. 2015 May;21(5):842-6. doi: 10.3201/eid2105.141927.

43.

Impaired Antibody-mediated Protection and Defective IgA B-Cell Memory in Experimental Infection of Adults with Respiratory Syncytial Virus.

Habibi MS, Jozwik A, Makris S, Dunning J, Paras A, DeVincenzo JP, de Haan CA, Wrammert J, Openshaw PJ, Chiu C; Mechanisms of Severe Acute Influenza Consortium Investigators.

Am J Respir Crit Care Med. 2015 May 1;191(9):1040-9. doi: 10.1164/rccm.201412-2256OC.

44.

Studying the dynamics of coronavirus replicative structures.

Hagemeijer MC, de Haan CA.

Methods Mol Biol. 2015;1282:261-9. doi: 10.1007/978-1-4939-2438-7_22.

PMID:
25720487
45.

A field-proven yeast two-hybrid protocol used to identify coronavirus-host protein-protein interactions.

Vidalain PO, Jacob Y, Hagemeijer MC, Jones LM, Neveu G, Roussarie JP, Rottier PJ, Tangy F, de Haan CA.

Methods Mol Biol. 2015;1282:213-29. doi: 10.1007/978-1-4939-2438-7_18.

PMID:
25720483
46.

Postcrisis redevelopment of sustainable healthcare systems.

Kanadanian KV, Haan CK.

Am J Disaster Med. 2014 Fall;9(4):247-58. doi: 10.5055/ajdm.2014.0177. Review.

PMID:
25672328
47.

ATP1A1-mediated Src signaling inhibits coronavirus entry into host cells.

Burkard C, Verheije MH, Haagmans BL, van Kuppeveld FJ, Rottier PJ, Bosch BJ, de Haan CA.

J Virol. 2015 Apr;89(8):4434-48. doi: 10.1128/JVI.03274-14. Epub 2015 Feb 4.

48.

Coronavirus cell entry occurs through the endo-/lysosomal pathway in a proteolysis-dependent manner.

Burkard C, Verheije MH, Wicht O, van Kasteren SI, van Kuppeveld FJ, Haagmans BL, Pelkmans L, Rottier PJ, Bosch BJ, de Haan CA.

PLoS Pathog. 2014 Nov 6;10(11):e1004502. doi: 10.1371/journal.ppat.1004502. eCollection 2014 Nov. Erratum in: PLoS Pathog. 2015 Feb;11(2):e1004709.

49.

Evaluation of nonspreading Rift Valley fever virus as a vaccine vector using influenza virus hemagglutinin as a model antigen.

Oreshkova N, Cornelissen LA, de Haan CA, Moormann RJ, Kortekaas J.

Vaccine. 2014 Sep 15;32(41):5323-9. doi: 10.1016/j.vaccine.2014.07.051. Epub 2014 Jul 25.

PMID:
25066737
50.

Dissecting virus entry: replication-independent analysis of virus binding, internalization, and penetration using minimal complementation of β-galactosidase.

Burkard C, Bloyet LM, Wicht O, van Kuppeveld FJ, Rottier PJ, de Haan CA, Bosch BJ.

PLoS One. 2014 Jul 15;9(7):e101762. doi: 10.1371/journal.pone.0101762. eCollection 2014.

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