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Items: 1 to 50 of 69

1.

CREBBP gene mutations are frequently detected in in situ follicular neoplasia.

Schmidt J, Ramis-Zaldivar JE, Bonzheim I, Steinhilber J, Müller I, Haake A, Yu SC, Raffeld M, Fend F, Salaverria I, Siebert R, Jaffe ES, Quintanilla-Martinez L.

Blood. 2018 Nov 6. pii: blood-2018-03-837039. doi: 10.1182/blood-2018-03-837039. [Epub ahead of print] No abstract available.

PMID:
30401710
2.

Effect of intraoperative positioning on postoperative neurological status in cats after perineal urethrostomy.

Slunsky P, Brunnberg M, Loderstedt S, Haake A, Brunnberg L.

J Feline Med Surg. 2018 Nov 5:1098612X18809188. doi: 10.1177/1098612X18809188. [Epub ahead of print]

PMID:
30392433
3.

Repair of a Tibiotarsal Fracture in a Pomeranian Goose ( Anser anser) With a Locking Plate.

Slunsky P, Weiß J, Haake A, Shahid M, Brunnberg L, Müller K.

J Avian Med Surg. 2018 Mar;32(1):50-56. doi: 10.1647/2016-242.

PMID:
29698075
4.

REPAIR OF A FEMORAL FRACTURE IN A CONGO AFRICAN GREY PARROT ( PSITTACUS ERITHACUS ERITHACUS) WITH A PARACORTICAL-CLAMP-CERCLAGE TECHNIQUE.

Slunsky P, Halter L, Florczak S, Haake A, Brunnberg L, Müller K.

J Zoo Wildl Med. 2017 Dec;48(4):1204-1209. doi: 10.1638/2016-0295R1.1.

PMID:
29297838
5.

Differences between BCL2-break positive and negative follicular lymphoma unraveled by whole-exome sequencing.

Zamò A, Pischimarov J, Schlesner M, Rosenstiel P, Bomben R, Horn H, Grieb T, Nedeva T, López C, Haake A, Richter J, Trümper L, Lawerenz C, Klapper W, Möller P, Hummel M, Lenze D, Szczepanowski M, Flossbach L, Schreder M, Gattei V, Ott G, Siebert R, Rosenwald A, Leich E.

Leukemia. 2018 Mar;32(3):685-693. doi: 10.1038/leu.2017.270. Epub 2017 Aug 21.

PMID:
28824170
6.

The B-cell receptor controls fitness of MYC-driven lymphoma cells via GSK3β inhibition.

Varano G, Raffel S, Sormani M, Zanardi F, Lonardi S, Zasada C, Perucho L, Petrocelli V, Haake A, Lee AK, Bugatti M, Paul U, Van Anken E, Pasqualucci L, Rabadan R, Siebert R, Kempa S, Ponzoni M, Facchetti F, Rajewsky K, Casola S.

Nature. 2017 Jun 8;546(7657):302-306. doi: 10.1038/nature22353. Epub 2017 May 31.

PMID:
28562582
7.

Alterations of microRNA and microRNA-regulated messenger RNA expression in germinal center B-cell lymphomas determined by integrative sequencing analysis.

Hezaveh K, Kloetgen A, Bernhart SH, Mahapatra KD, Lenze D, Richter J, Haake A, Bergmann AK, Brors B, Burkhardt B, Claviez A, Drexler HG, Eils R, Haas S, Hoffmann S, Karsch D, Klapper W, Kleinheinz K, Korbel J, Kretzmer H, Kreuz M, Küppers R, Lawerenz C, Leich E, Loeffler M, Mantovani-Loeffler L, López C, McHardy AC, Möller P, Rohde M, Rosenstiel P, Rosenwald A, Schilhabel M, Schlesner M, Scholz I, Stadler PF, Stilgenbauer S, Sungalee S, Szczepanowski M, Trümper L, Weniger MA, Siebert R, Borkhardt A, Hummel M, Hoell JI; ICGC MMML-Seq Project.

Haematologica. 2016 Nov;101(11):1380-1389. Epub 2016 Jul 6.

8.

Enabling Access to Medical and Health Education in Rwanda Using Mobile Technology: Needs Assessment for the Development of Mobile Medical Educator Apps.

Rusatira JC, Tomaszewski B, Dusabejambo V, Ndayiragije V, Gonsalves S, Sawant A, Mumararungu A, Gasana G, Amendezo E, Haake A, Mutesa L.

JMIR Med Educ. 2016 Jun 1;2(1):e7.

9.

Phenotypic spectrum and extent of DNA methylation defects associated with multilocus imprinting disturbances.

Bens S, Kolarova J, Beygo J, Buiting K, Caliebe A, Eggermann T, Gillessen-Kaesbach G, Prawitt D, Thiele-Schmitz S, Begemann M, Enklaar T, Gutwein J, Haake A, Paul U, Richter J, Soellner L, Vater I, Monk D, Horsthemke B, Ammerpohl O, Siebert R.

Epigenomics. 2016 Jun;8(6):801-16. doi: 10.2217/epi-2016-0007. Epub 2016 Jun 20.

PMID:
27323310
10.

Immunohistochemical detection of inhibitor of DNA binding 3 mutational variants in mature aggressive B-cell lymphoma.

Szczepanowski M, Masqué-Soler N, Schlesner M, Haake A, Richter J, Wagener R, Burkhardt B, Kreuz M, Siebert R; ICGC MMML-Seq Consortium, Klapper W.

Haematologica. 2016 Jun;101(6):e259-61. doi: 10.3324/haematol.2015.138701. Epub 2016 Mar 18. No abstract available.

11.

Quantitative DNA Methylation Profiling in Cancer.

Ammerpohl O, Haake A, Kolarova J, Siebert R.

Methods Mol Biol. 2016;1381:75-92. doi: 10.1007/978-1-4939-3204-7_5.

PMID:
26667456
12.

DNA methylome analysis in Burkitt and follicular lymphomas identifies differentially methylated regions linked to somatic mutation and transcriptional control.

Kretzmer H, Bernhart SH, Wang W, Haake A, Weniger MA, Bergmann AK, Betts MJ, Carrillo-de-Santa-Pau E, Doose G, Gutwein J, Richter J, Hovestadt V, Huang B, Rico D, Jühling F, Kolarova J, Lu Q, Otto C, Wagener R, Arnolds J, Burkhardt B, Claviez A, Drexler HG, Eberth S, Eils R, Flicek P, Haas S, Humme M, Karsch D, Kerstens HHD, Klapper W, Kreuz M, Lawerenz C, Lenzek D, Loeffler M, López C, MacLeod RAF, Martens JHA, Kulis M, Martín-Subero JI, Möller P, Nage I, Picelli S, Vater I, Rohde M, Rosenstiel P, Rosolowski M, Russell RB, Schilhabel M, Schlesner M, Stadler PF, Szczepanowski M, Trümper L, Stunnenberg HG, Küppers R, Ammerpohl O, Lichter P, Siebert R, Hoffmann S, Radlwimmer B.

Nat Genet. 2015 Nov;47(11):1316-1325. doi: 10.1038/ng.3413. Epub 2015 Oct 5.

13.

MINCR is a MYC-induced lncRNA able to modulate MYC's transcriptional network in Burkitt lymphoma cells.

Doose G, Haake A, Bernhart SH, López C, Duggimpudi S, Wojciech F, Bergmann AK, Borkhardt A, Burkhardt B, Claviez A, Dimitrova L, Haas S, Hoell JI, Hummel M, Karsch D, Klapper W, Kleo K, Kretzmer H, Kreuz M, Küppers R, Lawerenz C, Lenze D, Loeffler M, Mantovani-Löffler L, Möller P, Ott G, Richter J, Rohde M, Rosenstiel P, Rosenwald A, Schilhabel M, Schneider M, Scholz I, Stilgenbauer S, Stunnenberg HG, Szczepanowski M, Trümper L, Weniger MA; ICGC MMML-Seq Consortium, Hoffmann S, Siebert R, Iaccarino I.

Proc Natl Acad Sci U S A. 2015 Sep 22;112(38):E5261-70. doi: 10.1073/pnas.1505753112. Epub 2015 Sep 8.

14.

The PCBP1 gene encoding poly(rC) binding protein I is recurrently mutated in Burkitt lymphoma.

Wagener R, Aukema SM, Schlesner M, Haake A, Burkhardt B, Claviez A, Drexler HG, Hummel M, Kreuz M, Loeffler M, Rosolowski M, López C, Möller P, Richter J, Rohde M, Betts MJ, Russell RB, Bernhart SH, Hoffmann S, Rosenstiel P, Schilhabel M, Szczepanowski M, Trümper L, Klapper W, Siebert R; ICGC MMML-Seq-Project; "Molecular Mechanisms in Malignant Lymphomas" Network Project of the Deutsche Krebshilfe.

Genes Chromosomes Cancer. 2015 Sep;54(9):555-64. doi: 10.1002/gcc.22268. Epub 2015 Jul 14.

PMID:
26173642
15.

Analysis of mutational signatures in exomes from B-cell lymphoma cell lines suggest APOBEC3 family members to be involved in the pathogenesis of primary effusion lymphoma.

Wagener R, Alexandrov LB, Montesinos-Rongen M, Schlesner M, Haake A, Drexler HG, Richter J, Bignell GR, McDermott U, Siebert R.

Leukemia. 2015 Jul;29(7):1612-5. doi: 10.1038/leu.2015.22. Epub 2015 Feb 4. No abstract available.

PMID:
25650088
16.

The mutational pattern of primary lymphoma of the central nervous system determined by whole-exome sequencing.

Vater I, Montesinos-Rongen M, Schlesner M, Haake A, Purschke F, Sprute R, Mettenmeyer N, Nazzal I, Nagel I, Gutwein J, Richter J, Buchhalter I, Russell RB, Wiestler OD, Eils R, Deckert M, Siebert R.

Leukemia. 2015 Mar;29(3):677-85. doi: 10.1038/leu.2014.264. Epub 2014 Sep 5.

PMID:
25189415
17.

From spoken narratives to domain knowledge: mining linguistic data for medical image understanding.

Guo X, Yu Q, Alm CO, Calvelli C, Pelz JB, Shi P, Haake AR.

Artif Intell Med. 2014 Oct;62(2):79-90. doi: 10.1016/j.artmed.2014.08.001. Epub 2014 Aug 19.

PMID:
25174882
18.

Genomic and epigenomic co-evolution in follicular lymphomas.

Loeffler M, Kreuz M, Haake A, Hasenclever D, Trautmann H, Arnold C, Winter K, Koch K, Klapper W, Scholtysik R, Rosolowski M, Hoffmann S, Ammerpohl O, Szczepanowski M, Herrmann D, Küppers R, Pott C, Siebert R; HaematoSys-Project.

Leukemia. 2015 Feb;29(2):456-63. doi: 10.1038/leu.2014.209. Epub 2014 Jul 16.

PMID:
25027518
19.

The tissue is the issue: improved methylome analysis from paraffin-embedded tissues by application of the HOPE technique.

Marwitz S, Kolarova J, Reck M, Reinmuth N, Kugler C, Schädlich I, Haake A, Zabel P, Vollmer E, Siebert R, Goldmann T, Ammerpohl O.

Lab Invest. 2014 Aug;94(8):927-33. doi: 10.1038/labinvest.2014.79. Epub 2014 Jun 16.

20.

A familial disorder of altered DNA-methylation.

Caliebe A, Richter J, Ammerpohl O, Kanber D, Beygo J, Bens S, Haake A, Jüttner E, Korn B, Mackay DJ, Martin-Subero JI, Nagel I, Sebire NJ, Seidmann L, Vater I, von Kaisenberg CS, Temple IK, Horsthemke B, Buiting K, Siebert R.

J Med Genet. 2014 Jun;51(6):407-12. doi: 10.1136/jmedgenet-2013-102149. Epub 2014 Apr 10.

PMID:
24721835
21.

Recurrent mutation of JAK3 in T-cell prolymphocytic leukemia.

Bergmann AK, Schneppenheim S, Seifert M, Betts MJ, Haake A, Lopez C, Maria Murga Penas E, Vater I, Jayne S, Dyer MJ, Schrappe M, Dührsen U, Ammerpohl O, Russell RB, Küppers R, Dürig J, Siebert R.

Genes Chromosomes Cancer. 2014 Apr;53(4):309-16. doi: 10.1002/gcc.22141. Epub 2014 Jan 21.

PMID:
24446122
22.

Increasing genomic and epigenomic complexity in the clonal evolution from in situ to manifest t(14;18)-positive follicular lymphoma.

Schmidt J, Salaverria I, Haake A, Bonzheim I, Adam P, Montes-Moreno S, Piris MA, Fend F, Siebert R, Quintanilla-Martinez L.

Leukemia. 2014 May;28(5):1103-12. doi: 10.1038/leu.2013.307. Epub 2013 Oct 23.

PMID:
24153014
23.

Frequency and characterization of DNA methylation defects in children born SGA.

Bens S, Haake A, Richter J, Leohold J, Kolarova J, Vater I, Riepe FG, Buiting K, Eggermann T, Gillessen-Kaesbach G, Platzer K, Prawitt D, Caliebe A, Siebert R.

Eur J Hum Genet. 2013 Aug;21(8):838-43. doi: 10.1038/ejhg.2012.262. Epub 2012 Dec 12.

24.

Multiplex ligation-dependent probe amplification analysis of the NR0B1(DAX1) locus enables explanation of phenotypic differences in patients with X-linked congenital adrenal hypoplasia.

Barbaro M, Bens S, Haake A, Peter M, Brämswig J, Holterhus PM, Lopez-Siguero JP, Menken U, Mix M, Sippell WG, Wedell A, Riepe FG.

Horm Res Paediatr. 2012;77(2):100-7. doi: 10.1159/000336344. Epub 2012 Mar 23.

25.

A unique case of follicular lymphoma provides insights to the clonal evolution from follicular lymphoma in situ to manifest follicular lymphoma.

Bonzheim I, Salaverria I, Haake A, Gastl G, Adam P, Siebert R, Fend F, Quintanilla-Martinez L.

Blood. 2011 Sep 22;118(12):3442-4. doi: 10.1182/blood-2011-07-368944. No abstract available.

26.

Array-based DNA methylation analysis in classical Hodgkin lymphoma reveals new insights into the mechanisms underlying silencing of B cell-specific genes.

Ammerpohl O, Haake A, Pellissery S, Giefing M, Richter J, Balint B, Kulis M, Le J, Bibikova M, Drexler HG, Seifert M, Shaknovic R, Korn B, Küppers R, Martín-Subero JI, Siebert R.

Leukemia. 2012 Jan;26(1):185-8. doi: 10.1038/leu.2011.194. Epub 2011 Aug 5. No abstract available.

PMID:
21818115
27.

Pipeline for large-scale microdroplet bisulfite PCR-based sequencing allows the tracking of hepitype evolution in tumors.

Herrmann A, Haake A, Ammerpohl O, Martin-Guerrero I, Szafranski K, Stemshorn K, Nothnagel M, Kotsopoulos SK, Richter J, Warner J, Olson J, Link DR, Schreiber S, Krawczak M, Platzer M, Nürnberg P, Siebert R, Hampe J.

PLoS One. 2011;6(7):e21332. doi: 10.1371/journal.pone.0021332. Epub 2011 Jul 5.

28.

A de novo 1.1Mb microdeletion of chromosome 19p13.11 provides indirect evidence for EPS15L1 to be a strong candidate for split hand split foot malformation.

Bens S, Haake A, Tönnies H, Vater I, Stephani U, Holterhus PM, Siebert R, Caliebe A.

Eur J Med Genet. 2011 Sep-Oct;54(5):e501-4. doi: 10.1016/j.ejmg.2011.05.004. Epub 2011 Jun 7.

PMID:
21700002
29.

Distinct DNA methylation patterns in cirrhotic liver and hepatocellular carcinoma.

Ammerpohl O, Pratschke J, Schafmayer C, Haake A, Faber W, von Kampen O, Brosch M, Sipos B, von Schönfels W, Balschun K, Röcken C, Arlt A, Schniewind B, Grauholm J, Kalthoff H, Neuhaus P, Stickel F, Schreiber S, Becker T, Siebert R, Hampe J.

Int J Cancer. 2012 Mar 15;130(6):1319-28. doi: 10.1002/ijc.26136. Epub 2011 Jul 21.

30.

Somatic mutations altering Tyr641 of EZH2 are rare in primary central nervous system lymphoma.

Pellissery S, Richter J, Haake A, Montesinos-Rongen M, Deckert M, Siebert R.

Leuk Lymphoma. 2010 Nov;51(11):2135-6. doi: 10.3109/10428194.2010.510897. Epub 2010 Sep 21. No abstract available.

PMID:
20858097
31.

Conflicting results of prenatal FISH with different probes for Down's Syndrome critical regions associated with mosaicism for a de novo del(21)(q22) characterised by molecular karyotyping: Case report.

Eckmann-Scholz C, Gesk S, Nagel I, Haake A, Bens S, Heidemann S, Kautza M, Timke C, Siebert R, Caliebe A.

Mol Cytogenet. 2010 Sep 5;3:16. doi: 10.1186/1755-8166-3-16.

32.

Silver-Russell patients showing a broad range of ICR1 and ICR2 hypomethylation in different tissues.

Begemann M, Spengler S, Kanber D, Haake A, Baudis M, Leisten I, Binder G, Markus S, Rupprecht T, Segerer H, Fricke-Otto S, Mühlenberg R, Siebert R, Buiting K, Eggermann T.

Clin Genet. 2011 Jul;80(1):83-8. doi: 10.1111/j.1399-0004.2010.01514.x. Epub 2010 Jul 22.

PMID:
20738330
33.

Eye tracking users of a visual diagnostic clinical decision support system to discover decision-making strategies and to inform user interface design.

Haake AR, Pelz JB, Smagner J, Colombo D, Lindsay L, Papier A.

AMIA Annu Symp Proc. 2008 Nov 6:962.

PMID:
18999126
34.

High-throughput cell manipulation using ultrasound fields.

Kim DH, Haake A, Sun Y, Neild AP, Ihm JE, Dual J, Hubbell JA, Ju BK, Nelson BJ.

Conf Proc IEEE Eng Med Biol Soc. 2004;4:2571-4.

PMID:
17270799
35.

Finite element modeling of a microparticle manipulator.

Neild A, Oberti S, Haake A, Dual J.

Ultrasonics. 2006 Dec 22;44 Suppl 1:e455-60. Epub 2006 Jun 9.

PMID:
16797643
36.

Positioning, displacement, and localization of cells using ultrasonic forces.

Haake A, Neild A, Radziwill G, Dual J.

Biotechnol Bioeng. 2005 Oct 5;92(1):8-14.

PMID:
16094668
37.
38.

Manipulation of cells using an ultrasonic pressure field.

Haake A, Neild A, Kim DH, Ihm JE, Sun Y, Dual J, Ju BK.

Ultrasound Med Biol. 2005 Jun;31(6):857-64.

PMID:
15936501
39.

Positioning of small particles by an ultrasound field excited by surface waves.

Haake A, Dual J.

Ultrasonics. 2004 Apr;42(1-9):75-80.

PMID:
15047264
40.

Thalidomide inhibits UVB-induced mouse keratinocyte apoptosis by both TNF-alpha-dependent and TNF-alpha-independent pathways.

Lu KQ, Brenneman S, Burns R Jr, Vink A, Gaines E, Haake A, Gaspari A.

Photodermatol Photoimmunol Photomed. 2003 Dec;19(6):272-80.

PMID:
14617101
41.
42.

Bcl-2 overexpression protects human keratinocyte cells from Ukrain-induced apoptosis but not from G2/M arrest.

Roublevskaia IN, Haake AR, Polevoda BV.

Drugs Exp Clin Res. 2000;26(5-6):149-56.

PMID:
11345021
43.

Induced apoptosis in human prostate cancer cell line LNCaP by Ukrain.

Roublevskaia IN, Haake AR, Ludlow JW, Polevoda BV.

Drugs Exp Clin Res. 2000;26(5-6):141-7.

PMID:
11345020
44.

Induced G2/M arrest and apoptosis in human epidermoid carcinoma cell lines by semisynthetic drug Ukrain.

Roublevskaia IN, Polevoda BV, Ludlow JW, Haake AR.

Anticancer Res. 2000 Sep-Oct;20(5A):3163-7.

PMID:
11062738
45.
46.

Induction of TR4 orphan receptor by retinoic acid in human HaCaT keratinocytes.

Inui S, Lee YF, Haake AR, Goldsmith LA, Chang C.

J Invest Dermatol. 1999 Apr;112(4):426-31.

47.

Apoptosis: a role in skin aging?

Haake AR, Roublevskaia I, Cooklis M.

J Investig Dermatol Symp Proc. 1998 Aug;3(1):28-35. Review.

48.

Narrowing of the Darier disease gene interval on chromosome 12q.

Ikeda S, Shigihara T, Ogawa H, Haake A, Polakowska R, Roublevskaia I, Wakem P, Goldsmith LA, Epstein E Jr.

J Invest Dermatol. 1998 May;110(5):847-8. No abstract available.

49.

Bcl-2 overexpression in the HaCaT cell line is associated with a different membrane fatty acid composition and sensitivity to oxidative stress.

Virgili F, Santini MP, Canali R, Polakowska RR, Haake A, Perozzi G.

Free Radic Biol Med. 1998 Jan 1;24(1):93-101.

PMID:
9436618
50.

Autocrine nerve growth factor protects human keratinocytes from apoptosis through its high affinity receptor (TRK): a role for BCL-2.

Pincelli C, Haake AR, Benassi L, Grassilli E, Magnoni C, Ottani D, Polakowska R, Franceschi C, Giannetti A.

J Invest Dermatol. 1997 Dec;109(6):757-64.

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