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Items: 1 to 50 of 155

1.

Co-localization of Middle East respiratory syndrome coronavirus (MERS-CoV) and dipeptidyl peptidase-4 in the respiratory tract and lymphoid tissues of pigs and llamas.

Te N, Vergara-Alert J, Lehmbecker A, Pérez M, Haagmans BL, Baumgärtner W, Bensaid A, Segalés J.

Transbound Emerg Dis. 2018 Dec 6. doi: 10.1111/tbed.13092. [Epub ahead of print]

PMID:
30520548
2.

Multihospital Outbreak of a Middle East Respiratory Syndrome Coronavirus Deletion Variant, Jordan: A Molecular, Serologic, and Epidemiologic Investigation.

Payne DC, Biggs HM, Al-Abdallat MM, Alqasrawi S, Lu X, Abedi GR, Haddadin A, Iblan I, Alsanouri T, Al Nsour M, Sheikh Ali S, Rha B, Trivedi SU, Rasheed MAU, Tamin A, Lamers MM, Haagmans BL, Erdman DD, Thornburg NJ, Gerber SI.

Open Forum Infect Dis. 2018 Apr 28;5(5):ofy095. doi: 10.1093/ofid/ofy095. eCollection 2018 May.

3.

Chimeric camel/human heavy-chain antibodies protect against MERS-CoV infection.

Stalin Raj V, Okba NMA, Gutierrez-Alvarez J, Drabek D, van Dieren B, Widagdo W, Lamers MM, Widjaja I, Fernandez-Delgado R, Sola I, Bensaid A, Koopmans MP, Segalés J, Osterhaus ADME, Bosch BJ, Enjuanes L, Haagmans BL.

Sci Adv. 2018 Aug 8;4(8):eaas9667. doi: 10.1126/sciadv.aas9667. eCollection 2018 Aug.

4.

Experimental infection of dromedaries with Middle East respiratory syndrome-Coronavirus is accompanied by massive ciliary loss and depletion of the cell surface receptor dipeptidyl peptidase 4.

Haverkamp AK, Lehmbecker A, Spitzbarth I, Widagdo W, Haagmans BL, Segalés J, Vergara-Alert J, Bensaid A, van den Brand JMA, Osterhaus ADME, Baumgärtner W.

Sci Rep. 2018 Jun 27;8(1):9778. doi: 10.1038/s41598-018-28109-2.

5.

Middle East respiratory syndrome coronavirus specific antibodies in naturally exposed Israeli llamas, alpacas and camels.

David D, Rotenberg D, Khinich E, Erster O, Bardenstein S, van Straten M, Okba NMA, Raj SV, Haagmans BL, Miculitzki M, Davidson I.

One Health. 2018 May 4;5:65-68. doi: 10.1016/j.onehlt.2018.05.002. eCollection 2018 Jun.

6.

DPP4, the Middle East Respiratory Syndrome Coronavirus Receptor, is Upregulated in Lungs of Smokers and Chronic Obstructive Pulmonary Disease Patients.

Seys LJM, Widagdo W, Verhamme FM, Kleinjan A, Janssens W, Joos GF, Bracke KR, Haagmans BL, Brusselle GG.

Clin Infect Dis. 2018 Jan 6;66(1):45-53. doi: 10.1093/cid/cix741.

PMID:
29020176
7.

Identification of sialic acid-binding function for the Middle East respiratory syndrome coronavirus spike glycoprotein.

Li W, Hulswit RJG, Widjaja I, Raj VS, McBride R, Peng W, Widagdo W, Tortorici MA, van Dieren B, Lang Y, van Lent JWM, Paulson JC, de Haan CAM, de Groot RJ, van Kuppeveld FJM, Haagmans BL, Bosch BJ.

Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):E8508-E8517. doi: 10.1073/pnas.1712592114. Epub 2017 Sep 18.

8.

Identification of HCV Resistant Variants against Direct Acting Antivirals in Plasma and Liver of Treatment Naïve Patients.

Raj VS, Hundie GB, Schürch AC, Smits SL, Pas SD, Le Pogam S, Janssen HLA, de Knegt RJ, Osterhaus ADME, Najera I, Boucher CA, Haagmans BL.

Sci Rep. 2017 Jul 5;7(1):4688. doi: 10.1038/s41598-017-04931-y.

9.

Middle East respiratory syndrome coronavirus experimental transmission using a pig model.

Vergara-Alert J, Raj VS, Muñoz M, Abad FX, Cordón I, Haagmans BL, Bensaid A, Segalés J.

Transbound Emerg Dis. 2017 Oct;64(5):1342-1345. doi: 10.1111/tbed.12668. Epub 2017 Jun 26.

PMID:
28653496
10.

MERS-coronavirus: From discovery to intervention.

Widagdo W, Okba NMA, Stalin Raj V, Haagmans BL.

One Health. 2016 Dec 23;3:11-16. doi: 10.1016/j.onehlt.2016.12.001. eCollection 2017 Jun. Review.

11.

Genetic diversity of hepatitis C virus in Ethiopia.

Hundie GB, Raj VS, GebreMichael D, Pas SD, Haagmans BL.

PLoS One. 2017 Jun 1;12(6):e0179064. doi: 10.1371/journal.pone.0179064. eCollection 2017.

12.

Tissue Distribution of the MERS-Coronavirus Receptor in Bats.

Widagdo W, Begeman L, Schipper D, Run PRV, Cunningham AA, Kley N, Reusken CB, Haagmans BL, van den Brand JMA.

Sci Rep. 2017 Apr 26;7(1):1193. doi: 10.1038/s41598-017-01290-6.

13.

Middle East respiratory syndrome coronavirus vaccines: current status and novel approaches.

Okba NM, Raj VS, Haagmans BL.

Curr Opin Virol. 2017 Apr;23:49-58. doi: 10.1016/j.coviro.2017.03.007. Epub 2017 Apr 13. Review.

14.

Virus genomes reveal factors that spread and sustained the Ebola epidemic.

Dudas G, Carvalho LM, Bedford T, Tatem AJ, Baele G, Faria NR, Park DJ, Ladner JT, Arias A, Asogun D, Bielejec F, Caddy SL, Cotten M, D'Ambrozio J, Dellicour S, Di Caro A, Diclaro JW, Duraffour S, Elmore MJ, Fakoli LS, Faye O, Gilbert ML, Gevao SM, Gire S, Gladden-Young A, Gnirke A, Goba A, Grant DS, Haagmans BL, Hiscox JA, Jah U, Kugelman JR, Liu D, Lu J, Malboeuf CM, Mate S, Matthews DA, Matranga CB, Meredith LW, Qu J, Quick J, Pas SD, Phan MVT, Pollakis G, Reusken CB, Sanchez-Lockhart M, Schaffner SF, Schieffelin JS, Sealfon RS, Simon-Loriere E, Smits SL, Stoecker K, Thorne L, Tobin EA, Vandi MA, Watson SJ, West K, Whitmer S, Wiley MR, Winnicki SM, Wohl S, Wölfel R, Yozwiak NL, Andersen KG, Blyden SO, Bolay F, Carroll MW, Dahn B, Diallo B, Formenty P, Fraser C, Gao GF, Garry RF, Goodfellow I, Günther S, Happi CT, Holmes EC, Kargbo B, Keïta S, Kellam P, Koopmans MPG, Kuhn JH, Loman NJ, Magassouba N, Naidoo D, Nichol ST, Nyenswah T, Palacios G, Pybus OG, Sabeti PC, Sall A, Ströher U, Wurie I, Suchard MA, Lemey P, Rambaut A.

Nature. 2017 Apr 20;544(7650):309-315. doi: 10.1038/nature22040. Epub 2017 Apr 12.

15.

Risk Factors for Primary Middle East Respiratory Syndrome Coronavirus Infection in Camel Workers in Qatar During 2013-2014: A Case-Control Study.

Sikkema RS, Farag EABA, Himatt S, Ibrahim AK, Al-Romaihi H, Al-Marri SA, Al-Thani M, El-Sayed AM, Al-Hajri M, Haagmans BL, Koopmans MPG, Reusken CBEM.

J Infect Dis. 2017 Jun 1;215(11):1702-1705. doi: 10.1093/infdis/jix174.

PMID:
28387845
16.

Seroepidemiology of hepatitis B and C virus infections among blood donors in Ethiopia.

Hundie GB, Raj VS, GebreMichael D, Haagmans BL.

J Med Virol. 2017 Jul;89(7):1300-1303. doi: 10.1002/jmv.24770. Epub 2017 Feb 27.

PMID:
28121005
17.

Livestock Susceptibility to Infection with Middle East Respiratory Syndrome Coronavirus.

Vergara-Alert J, van den Brand JM, Widagdo W, Muñoz M 5th, Raj S, Schipper D, Solanes D, Cordón I, Bensaid A, Haagmans BL, Segalés J.

Emerg Infect Dis. 2017 Feb;23(2):232-240. doi: 10.3201/eid2302.161239. Epub 2017 Feb 15.

18.

A novel hepatitis B virus subgenotype D10 circulating in Ethiopia.

Hundie GB, Stalin Raj V, Gebre Michael D, Pas SD, Koopmans MP, Osterhaus AD, Smits SL, Haagmans BL.

J Viral Hepat. 2017 Feb;24(2):163-173. doi: 10.1111/jvh.12631. Epub 2016 Nov 3.

PMID:
27808472
19.

Miscarriage Associated with Zika Virus Infection.

van der Eijk AA, van Genderen PJ, Verdijk RM, Reusken CB, Mögling R, van Kampen JJ, Widagdo W, Aron GI, GeurtsvanKessel CH, Pas SD, Raj VS, Haagmans BL, Koopmans MP.

N Engl J Med. 2016 Sep 8;375(10):1002-4. doi: 10.1056/NEJMc1605898. Epub 2016 Jul 27. No abstract available.

20.

Naturally occurring recombination in ferret coronaviruses revealed by complete genome characterization.

Lamers MM, Smits SL, Hundie GB, Provacia LB, Koopmans M, Osterhaus AD, Haagmans BL, Raj VS.

J Gen Virol. 2016 Sep;97(9):2180-6. doi: 10.1099/jgv.0.000520. Epub 2016 Jun 7.

PMID:
27283016
21.

MERS-CoV Infection of Alpaca in a Region Where MERS-CoV is Endemic.

Reusken CB, Schilp C, Raj VS, De Bruin E, Kohl RH, Farag EA, Haagmans BL, Al-Romaihi H, Le Grange F, Bosch BJ, Koopmans MP.

Emerg Infect Dis. 2016 Jun;22(6):1129-31. doi: 10.3201/eid2206.152113. Epub 2016 Jun 15. No abstract available.

22.

Deletion Variants of Middle East Respiratory Syndrome Coronavirus from Humans, Jordan, 2015.

Lamers MM, Raj VS, Shafei M, Ali SS, Abdallh SM, Gazo M, Nofal S, Lu X, Erdman DD, Koopmans MP, Abdallat M, Haddadin A, Haagmans BL.

Emerg Infect Dis. 2016 Apr;22(4):716-9. doi: 10.3201/eid2204.152065.

23.

Hepatitis E Virus (HEV) Genotype 3 Infection of Human Liver Chimeric Mice as a Model for Chronic HEV Infection.

van de Garde MD, Pas SD, van der Net G, de Man RA, Osterhaus AD, Haagmans BL, Boonstra A, Vanwolleghem T.

J Virol. 2016 Apr 14;90(9):4394-401. doi: 10.1128/JVI.00114-16. Print 2016 May.

24.

Differential Expression of the Middle East Respiratory Syndrome Coronavirus Receptor in the Upper Respiratory Tracts of Humans and Dromedary Camels.

Widagdo W, Raj VS, Schipper D, Kolijn K, van Leenders GJLH, Bosch BJ, Bensaid A, Segalés J, Baumgärtner W, Osterhaus ADME, Koopmans MP, van den Brand JMA, Haagmans BL.

J Virol. 2016 Apr 14;90(9):4838-4842. doi: 10.1128/JVI.02994-15. Print 2016 May.

25.

Cross host transmission in the emergence of MERS coronavirus.

Reusken CB, Raj VS, Koopmans MP, Haagmans BL.

Curr Opin Virol. 2016 Feb;16:55-62. doi: 10.1016/j.coviro.2016.01.004. Epub 2016 Jan 29. Review.

26.

The sample of choice for detecting Middle East respiratory syndrome coronavirus in asymptomatic dromedary camels using real-time reversetranscription polymerase chain reaction.

Mohran KA, Farag EA, Reusken CB, Raj VS, Lamers MM, Pas SD, Voermans J, Smits SL, Alhajri MM, Alhajri F, Al-Romaihi HE, Ghobashy H, El-Maghraby MM, Al Dhahiry SH, Al-Mawlawi N, El-Sayed AM, Al-Thani M, Al-Marri SA, Haagmans BL, Koopmans MP.

Rev Sci Tech. 2016 Dec;35(3):905-911. doi: 10.20506/rst.35.3.2578.

PMID:
28332641
27.

An orthopoxvirus-based vaccine reduces virus excretion after MERS-CoV infection in dromedary camels.

Haagmans BL, van den Brand JM, Raj VS, Volz A, Wohlsein P, Smits SL, Schipper D, Bestebroer TM, Okba N, Fux R, Bensaid A, Solanes Foz D, Kuiken T, Baumgärtner W, Segalés J, Sutter G, Osterhaus AD.

Science. 2016 Jan 1;351(6268):77-81. doi: 10.1126/science.aad1283. Epub 2015 Dec 17.

28.

Molecular epidemiology and genetic diversity of hepatitis B virus in Ethiopia.

Hundie GB, Raj VS, Michael DG, Pas SD, Osterhaus AD, Koopmans MP, Smits SL, Haagmans BL.

J Med Virol. 2016 Jun;88(6):1035-43. doi: 10.1002/jmv.24437. Epub 2015 Dec 22.

PMID:
26629781
29.

Genotypic anomaly in Ebola virus strains circulating in Magazine Wharf area, Freetown, Sierra Leone, 2015.

Smits SL, Pas SD, Reusken CB, Haagmans BL, Pertile P, Cancedda C, Dierberg K, Wurie I, Kamara A, Kargbo D, Caddy SL, Arias A, Thorne L, Lu J, Jah U, Goodfellow I, Koopmans MP.

Euro Surveill. 2015;20(40). doi: 10.2807/1560-7917.ES.2015.20.40.30035.

30.

Intrathecal CD4(+) and CD8(+) T-cell responses to endogenously synthesized candidate disease-associated human autoantigens in multiple sclerosis patients.

van Nierop GP, Janssen M, Mitterreiter JG, van de Vijver DA, de Swart RL, Haagmans BL, Verjans GM, Hintzen RQ.

Eur J Immunol. 2016 Feb;46(2):347-53. doi: 10.1002/eji.201545921. Epub 2015 Nov 9.

31.

Occupational Exposure to Dromedaries and Risk for MERS-CoV Infection, Qatar, 2013-2014.

Reusken CB, Farag EA, Haagmans BL, Mohran KA, Godeke GJ 5th, Raj S, Alhajri F, Al-Marri SA, Al-Romaihi HE, Al-Thani M, Bosch BJ, van der Eijk AA, El-Sayed AM, Ibrahim AK, Al-Molawi N, Müller MA, Pasha SK, Drosten C, AlHajri MM, Koopmans MP.

Emerg Infect Dis. 2015 Aug;21(8):1422-5. doi: 10.3201/eid2108.150481.

32.

High proportion of MERS-CoV shedding dromedaries at slaughterhouse with a potential epidemiological link to human cases, Qatar 2014.

Farag EA, Reusken CB, Haagmans BL, Mohran KA, Stalin Raj V, Pas SD, Voermans J, Smits SL, Godeke GJ, Al-Hajri MM, Alhajri FH, Al-Romaihi HE, Ghobashy H, El-Maghraby MM, El-Sayed AM, Al Thani MH, Al-Marri S, Koopmans MP.

Infect Ecol Epidemiol. 2015 Jul 15;5:28305. doi: 10.3402/iee.v5.28305. eCollection 2015.

33.

Detection of Circovirus in Foxes with Meningoencephalitis, United Kingdom, 2009-2013.

Bexton S, Wiersma LC, Getu S, van Run PR, Verjans GM, Schipper D, Schapendonk CM, Bodewes R, Oldroyd L, Haagmans BL, Koopmans MM, Smits SL.

Emerg Infect Dis. 2015 Jul;21(7):1205-8. doi: 10.3201/eid2107.150228.

34.

Asymptomatic Middle East respiratory syndrome coronavirus infection in rabbits.

Haagmans BL, van den Brand JM, Provacia LB, Raj VS, Stittelaar KJ, Getu S, de Waal L, Bestebroer TM, van Amerongen G, Verjans GM, Fouchier RA, Smits SL, Kuiken T, Osterhaus AD.

J Virol. 2015 Jun;89(11):6131-5. doi: 10.1128/JVI.00661-15. Epub 2015 Mar 25.

35.

Reliable typing of MERS-CoV variants with a small genome fragment.

Smits SL, Raj VS, Pas SD, Reusken CB, Mohran K, Farag EA, Al-Romaihi HE, AlHajri MM, Haagmans BL, Koopmans MP.

J Clin Virol. 2015 Mar;64:83-7. doi: 10.1016/j.jcv.2014.12.006. Epub 2014 Dec 15.

36.

Identification of protein receptors for coronaviruses by mass spectrometry.

Raj VS, Lamers MM, Smits SL, Demmers JA, Mou H, Bosch BJ, Haagmans BL.

Methods Mol Biol. 2015;1282:165-82. doi: 10.1007/978-1-4939-2438-7_15.

PMID:
25720480
37.

ATP1A1-mediated Src signaling inhibits coronavirus entry into host cells.

Burkard C, Verheije MH, Haagmans BL, van Kuppeveld FJ, Rottier PJ, Bosch BJ, de Haan CA.

J Virol. 2015 Apr;89(8):4434-48. doi: 10.1128/JVI.03274-14. Epub 2015 Feb 4.

38.

Genome sequence of enterovirus D68 and clinical disease, Thailand.

Vongpunsawad S, Prachayangprecha S, Chansaenroj J, Haagmans BL, Smits SL, Poovorawan Y.

Emerg Infect Dis. 2015 Feb;21(2):384. doi: 10.3201/eid2102.141742. No abstract available.

39.

Coronavirus cell entry occurs through the endo-/lysosomal pathway in a proteolysis-dependent manner.

Burkard C, Verheije MH, Wicht O, van Kasteren SI, van Kuppeveld FJ, Haagmans BL, Pelkmans L, Rottier PJ, Bosch BJ, de Haan CA.

PLoS Pathog. 2014 Nov 6;10(11):e1004502. doi: 10.1371/journal.ppat.1004502. eCollection 2014 Nov. Erratum in: PLoS Pathog. 2015 Feb;11(2):e1004709.

40.

Pathogenesis of Middle East respiratory syndrome coronavirus.

van den Brand JM, Smits SL, Haagmans BL.

J Pathol. 2015 Jan;235(2):175-84. doi: 10.1002/path.4458. Review.

PMID:
25294366
41.

Virological and serological analysis of a recent Middle East respiratory syndrome coronavirus infection case on a triple combination antiviral regimen.

Spanakis N, Tsiodras S, Haagmans BL, Raj VS, Pontikis K, Koutsoukou A, Koulouris NG, Osterhaus AD, Koopmans MP, Tsakris A.

Int J Antimicrob Agents. 2014 Dec;44(6):528-32. doi: 10.1016/j.ijantimicag.2014.07.026. Epub 2014 Sep 18.

PMID:
25288266
42.

[Dromedary camels and Middle East respiratory syndrome: MERS coronavirus in the 'ship of the desert'].

Reusken C, Haagmans BL, Koopmans MP.

Ned Tijdschr Geneeskd. 2014;158:A7806. Review. Dutch.

PMID:
25248734
43.

Immunogenicity of an adenoviral-based Middle East Respiratory Syndrome coronavirus vaccine in BALB/c mice.

Kim E, Okada K, Kenniston T, Raj VS, AlHajri MM, Farag EA, AlHajri F, Osterhaus AD, Haagmans BL, Gambotto A.

Vaccine. 2014 Oct 14;32(45):5975-82. doi: 10.1016/j.vaccine.2014.08.058. Epub 2014 Sep 3.

PMID:
25192975
44.

Metagenomic survey for viruses in Western Arctic caribou, Alaska, through iterative assembly of taxonomic units.

Schürch AC, Schipper D, Bijl MA, Dau J, Beckmen KB, Schapendonk CM, Raj VS, Osterhaus AD, Haagmans BL, Tryland M, Smits SL.

PLoS One. 2014 Aug 20;9(8):e105227. doi: 10.1371/journal.pone.0105227. eCollection 2014.

45.

Exploring the potential of next-generation sequencing in detection of respiratory viruses.

Prachayangprecha S, Schapendonk CM, Koopmans MP, Osterhaus AD, Schürch AC, Pas SD, van der Eijk AA, Poovorawan Y, Haagmans BL, Smits SL.

J Clin Microbiol. 2014 Oct;52(10):3722-30. doi: 10.1128/JCM.01641-14. Epub 2014 Aug 6.

46.

Isolation of MERS coronavirus from a dromedary camel, Qatar, 2014.

Raj VS, Farag EA, Reusken CB, Lamers MM, Pas SD, Voermans J, Smits SL, Osterhaus AD, Al-Mawlawi N, Al-Romaihi HE, AlHajri MM, El-Sayed AM, Mohran KA, Ghobashy H, Alhajri F, Al-Thani M, Al-Marri SA, El-Maghraby MM, Koopmans MP, Haagmans BL.

Emerg Infect Dis. 2014 Aug;20(8):1339-42. doi: 10.3201/eid2008.140663.

47.

Novel divergent nidovirus in a python with pneumonia.

Bodewes R, Lempp C, Schürch AC, Habierski A, Hahn K, Lamers M, von Dörnberg K, Wohlsein P, Drexler JF, Haagmans BL, Smits SL, Baumgärtner W, Osterhaus AD.

J Gen Virol. 2014 Nov;95(Pt 11):2480-5. doi: 10.1099/vir.0.068700-0. Epub 2014 Jul 25.

PMID:
25063552
48.

Geographic distribution of MERS coronavirus among dromedary camels, Africa.

Reusken CB, Messadi L, Feyisa A, Ularamu H, Godeke GJ, Danmarwa A, Dawo F, Jemli M, Melaku S, Shamaki D, Woma Y, Wungak Y, Gebremedhin EZ, Zutt I, Bosch BJ, Haagmans BL, Koopmans MP.

Emerg Infect Dis. 2014 Aug;20(8):1370-4. doi: 10.3201/eid2008.140590.

49.

New viruses in idiopathic human diarrhea cases, the Netherlands.

Smits SL, Schapendonk CM, van Beek J, Vennema H, Schürch AC, Schipper D, Bodewes R, Haagmans BL, Osterhaus AD, Koopmans MP.

Emerg Infect Dis. 2014 Jul;20(7):1218-22. doi: 10.3201/eid2007.140190.

50.

Middle East respiratory syndrome coronavirus (MERS-CoV) RNA and neutralising antibodies in milk collected according to local customs from dromedary camels, Qatar, April 2014.

Reusken CB, Farag EA, Jonges M, Godeke GJ, El-Sayed AM, Pas SD, Raj VS, Mohran KA, Moussa HA, Ghobashy H, Alhajri F, Ibrahim AK, Bosch BJ, Pasha SK, Al-Romaihi HE, Al-Thani M, Al-Marri SA, AlHajri MM, Haagmans BL, Koopmans MP.

Euro Surveill. 2014 Jun 12;19(23). pii: 20829.

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