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Items: 1 to 50 of 83

1.

Immunoresolvent Resolvin D1 Maintains the Health of the Ocular Surface.

Dartt DA, Hodges RR, Serhan CN.

Adv Exp Med Biol. 2019;1161:13-25. doi: 10.1007/978-3-030-21735-8_3. Review.

2.

Resolvin D2 elevates cAMP to increase intracellular [Ca2+] and stimulate secretion from conjunctival goblet cells.

Botten N, Hodges RR, Li D, Bair JA, Shatos MA, Utheim TP, Serhan CN, Dartt DA.

FASEB J. 2019 Jul;33(7):8468-8478. doi: 10.1096/fj.201802467R. Epub 2019 Apr 23.

PMID:
31013438
3.

Resolvin D1, but not resolvin E1, transactivates the epidermal growth factor receptor to increase intracellular calcium and glycoconjugate secretion in rat and human conjunctival goblet cells.

Kaye R, Botten N, Lippestad M, Li D, Hodges RR, Utheim TP, Serhan CN, Dartt DA.

Exp Eye Res. 2019 Mar;180:53-62. doi: 10.1016/j.exer.2018.11.018. Epub 2018 Dec 1.

PMID:
30513286
4.

Thrombospondin-1 Is Necessary for the Development and Repair of Corneal Nerves.

Tatematsu Y, Khan Q, Blanco T, Bair JA, Hodges RR, Masli S, Dartt DA.

Int J Mol Sci. 2018 Oct 16;19(10). pii: E3191. doi: 10.3390/ijms19103191.

5.

Resolvin D1 treatment on goblet cell mucin and immune responses in the chronic allergic eye disease (AED) model.

Saban DR, Hodges RR, Mathew R, Reyes NJ, Yu C, Kaye R, Swift W, Botten N, Serhan CN, Dartt DA.

Mucosal Immunol. 2019 Jan;12(1):145-153. doi: 10.1038/s41385-018-0089-1. Epub 2018 Oct 2.

6.

Context-Dependent Regulation of Conjunctival Goblet Cell Function by Allergic Mediators.

García-Posadas L, Hodges RR, Diebold Y, Dartt DA.

Sci Rep. 2018 Aug 15;8(1):12162. doi: 10.1038/s41598-018-30002-x.

7.

Activation of the EGF Receptor by Histamine Receptor Subtypes Stimulates Mucin Secretion in Conjunctival Goblet Cells.

He M, Lippestad M, Li D, Hodges RR, Utheim TP, Dartt DA.

Invest Ophthalmol Vis Sci. 2018 Jul 2;59(8):3543-3553. doi: 10.1167/iovs.18-2476.

8.

Signaling pathways activated by resolvin E1 to stimulate mucin secretion and increase intracellular Ca2+ in cultured rat conjunctival goblet cells.

Lippestad M, Hodges RR, Utheim TP, Serhan CN, Dartt DA.

Exp Eye Res. 2018 Aug;173:64-72. doi: 10.1016/j.exer.2018.04.015. Epub 2018 Apr 25.

9.

Alteration in nerves and neurotransmitter stimulation of lacrimal gland secretion in the TSP-1-/- mouse model of aqueous deficiency dry eye.

Bhattacharya S, García-Posadas L, Hodges RR, Makarenkova HP, Masli S, Dartt DA.

Mucosal Immunol. 2018 Jul;11(4):1138-1148. doi: 10.1038/s41385-018-0002-y. Epub 2018 Feb 14.

10.

Neither non-toxigenic Staphylococcus aureus nor commensal S. epidermidi activates NLRP3 inflammasomes in human conjunctival goblet cells.

Li D, Hodges RR, Bispo P, Gilmore MS, Gregory-Ksander M, Dartt DA.

BMJ Open Ophthalmol. 2017 Nov 16;2(1):e000101. doi: 10.1136/bmjophth-2017-000101. eCollection 2017.

11.

Resolvin D1 Increases Mucin Secretion in Cultured Rat Conjunctival Goblet Cells via Multiple Signaling Pathways.

Lippestad M, Hodges RR, Utheim TP, Serhan CN, Dartt DA.

Invest Ophthalmol Vis Sci. 2017 Sep 1;58(11):4530-4544. doi: 10.1167/iovs.17-21914.

12.

Identification and Profiling of Specialized Pro-Resolving Mediators in Human Tears by Lipid Mediator Metabolomics.

English JT, Norris PC, Hodges RR, Dartt DA, Serhan CN.

Prostaglandins Leukot Essent Fatty Acids. 2017 Feb;117:17-27. doi: 10.1016/j.plefa.2017.01.004. Epub 2017 Jan 19.

13.

Artificial Polymeric Scaffolds as Extracellular Matrix Substitutes for Autologous Conjunctival Goblet Cell Expansion.

He M, Storr-Paulsen T, Wang AL, Ghezzi CE, Wang S, Fullana M, Karamichos D, Utheim TP, Islam R, Griffith M, Islam MM, Hodges RR, Wnek GE, Kaplan DL, Dartt DA.

Invest Ophthalmol Vis Sci. 2016 Nov 1;57(14):6134-6146. doi: 10.1167/iovs.16-20081.

14.

Lipoxin A4 Counter-regulates Histamine-stimulated Glycoconjugate Secretion in Conjunctival Goblet Cells.

Hodges RR, Li D, Shatos MA, Serhan CN, Dartt DA.

Sci Rep. 2016 Nov 8;6:36124. doi: 10.1038/srep36124.

15.

Alteration in cellular turnover and progenitor cell population in lacrimal glands from thrombospondin 1-/- mice, a model of dry eye.

Shatos MA, Hodges RR, Morinaga M, McNay DE, Islam R, Bhattacharya S, Li D, Turpie B, Makarenkova HP, Masli S, Utheim TP, Dartt DA.

Exp Eye Res. 2016 Dec;153:27-41. doi: 10.1016/j.exer.2016.09.011. Epub 2016 Sep 30.

16.

Signaling Pathways of Purinergic Receptors and Their Interactions with Cholinergic and Adrenergic Pathways in the Lacrimal Gland.

Hodges RR, Dartt DA.

J Ocul Pharmacol Ther. 2016 Oct;32(8):490-497. Epub 2016 Jul 27. Review.

17.

Lipoxin A4 activates ALX/FPR2 receptor to regulate conjunctival goblet cell secretion.

Hodges RR, Li D, Shatos MA, Bair JA, Lippestad M, Serhan CN, Dartt DA.

Mucosal Immunol. 2017 Jan;10(1):46-57. doi: 10.1038/mi.2016.33. Epub 2016 Apr 13.

18.

Interaction of IFN-γ with cholinergic agonists to modulate rat and human goblet cell function.

García-Posadas L, Hodges RR, Li D, Shatos MA, Storr-Paulsen T, Diebold Y, Dartt DA.

Mucosal Immunol. 2016 Jan;9(1):206-17. doi: 10.1038/mi.2015.53. Epub 2015 Jul 1.

19.

Staphylococcus aureus activates the NLRP3 inflammasome in human and rat conjunctival goblet cells.

McGilligan VE, Gregory-Ksander MS, Li D, Moore JE, Hodges RR, Gilmore MS, Moore TC, Dartt DA.

PLoS One. 2013 Sep 10;8(9):e74010. doi: 10.1371/journal.pone.0074010. eCollection 2013.

20.

Tear film mucins: front line defenders of the ocular surface; comparison with airway and gastrointestinal tract mucins.

Hodges RR, Dartt DA.

Exp Eye Res. 2013 Dec;117:62-78. doi: 10.1016/j.exer.2013.07.027. Epub 2013 Aug 14.

21.

Role of PKCα activation of Src, PI-3K/AKT, and ERK in EGF-stimulated proliferation of rat and human conjunctival goblet cells.

Li D, Shatos MA, Hodges RR, Dartt DA.

Invest Ophthalmol Vis Sci. 2013 Aug 21;54(8):5661-74. doi: 10.1167/iovs.13-12473.

22.

Effect of VIP on intracellular [Ca2+], extracellular regulated kinase 1/2, and secretion in cultured rat conjunctival goblet cells.

Li D, Jiao J, Shatos MA, Hodges RR, Dartt DA.

Invest Ophthalmol Vis Sci. 2013 Apr 23;54(4):2872-84. doi: 10.1167/iovs.12-11264.

23.

Resolvin D1 and aspirin-triggered resolvin D1 regulate histamine-stimulated conjunctival goblet cell secretion.

Li D, Hodges RR, Jiao J, Carozza RB, Shatos MA, Chiang N, Serhan CN, Dartt DA.

Mucosal Immunol. 2013 Nov;6(6):1119-30. doi: 10.1038/mi.2013.7. Epub 2013 Mar 6.

24.

Signaling pathways used by EGF to stimulate conjunctival goblet cell secretion.

Hodges RR, Bair JA, Carozza RB, Li D, Shatos MA, Dartt DA.

Exp Eye Res. 2012 Oct;103:99-113. doi: 10.1016/j.exer.2012.08.010. Epub 2012 Sep 4.

25.

Effect of histamine on Ca(2+)-dependent signaling pathways in rat conjunctival goblet cells.

Li D, Carozza RB, Shatos MA, Hodges RR, Dartt DA.

Invest Ophthalmol Vis Sci. 2012 Oct 5;53(11):6928-38. doi: 10.1167/iovs.12-10163. Erratum in: Invest Ophthalmol Vis Sci. 2012 Nov;53(11):7380.

26.

Role of histamine and its receptor subtypes in stimulation of conjunctival goblet cell secretion.

Hayashi D, Li D, Hayashi C, Shatos M, Hodges RR, Dartt DA.

Invest Ophthalmol Vis Sci. 2012 May 17;53(6):2993-3003. doi: 10.1167/iovs.11-8748.

27.

Isolation and characterization of progenitor cells in uninjured, adult rat lacrimal gland.

Shatos MA, Haugaard-Kedstrom L, Hodges RR, Dartt DA.

Invest Ophthalmol Vis Sci. 2012 May 14;53(6):2749-59. doi: 10.1167/iovs.11-9025.

28.

Increase of intracellular Ca2+ by purinergic receptors in cultured rat lacrimal gland myoepithelial cells.

Ohtomo K, Shatos MA, Vrouvlianis J, Li D, Hodges RR, Dartt DA.

Invest Ophthalmol Vis Sci. 2011 Dec 16;52(13):9503-15. doi: 10.1167/iovs.11-7809.

29.
30.

Cholinergic agonists activate P2X7 receptors to stimulate protein secretion by the rat lacrimal gland.

Dartt DA, Hodges RR.

Invest Ophthalmol Vis Sci. 2011 May 1;52(6):3381-90. doi: 10.1167/iovs.11-7210.

31.

Identification of P2X₃ and P2X₇ purinergic receptors activated by ATP in rat lacrimal gland.

Hodges RR, Vrouvlianis J, Scott R, Dartt DA.

Invest Ophthalmol Vis Sci. 2011 May 17;52(6):3254-63. doi: 10.1167/iovs.10-7042.

32.

Conjunctival goblet cell secretion stimulated by leukotrienes is reduced by resolvins D1 and E1 to promote resolution of inflammation.

Dartt DA, Hodges RR, Li D, Shatos MA, Lashkari K, Serhan CN.

J Immunol. 2011 Apr 1;186(7):4455-66. doi: 10.4049/jimmunol.1000833. Epub 2011 Feb 28.

33.

Phospholipase D1, but not D2, regulates protein secretion via Rho/ROCK in a Ras/Raf-independent, MEK-dependent manner in rat lacrimal gland.

Hodges RR, Guilbert E, Shatos MA, Natarajan V, Dartt DA.

Invest Ophthalmol Vis Sci. 2011 Apr 6;52(5):2199-210. doi: 10.1167/iovs.10-6209. Print 2011 Apr.

34.

Identification of the Raf-1 signaling pathway used by cAMP to inhibit p42/p44 MAPK in rat lacrimal gland acini: role in potentiation of protein secretion.

Funaki C, Hodges RR, Dartt DA.

Invest Ophthalmol Vis Sci. 2010 Dec;51(12):6321-8. doi: 10.1167/iovs.10-5690. Epub 2010 Jul 29.

35.

Characterization of P2X7 purinergic receptors and their function in rat lacrimal gland.

Hodges RR, Vrouvlianis J, Shatos MA, Dartt DA.

Invest Ophthalmol Vis Sci. 2009 Dec;50(12):5681-9. doi: 10.1167/iovs.09-3670. Epub 2009 Jul 15.

36.

Stimulatory role of PKCalpha in extracellular regulated kinase 1/2 pathway in conjunctival goblet cell proliferation.

Shatos MA, Hodges RR, Bair JA, Lashkari K, Dartt DA.

Invest Ophthalmol Vis Sci. 2009 Apr;50(4):1619-25. doi: 10.1167/iovs.08-2930. Epub 2008 Dec 13.

37.

Role of cPKCalpha and nPKCepsilon in EGF-stimulated goblet cell proliferation.

Shatos MA, Hodges RR, Oshi Y, Bair JA, Zoukhri D, Kublin C, Lashkari K, Dartt DA.

Invest Ophthalmol Vis Sci. 2009 Feb;50(2):614-20. doi: 10.1167/iovs.08-2467. Epub 2008 Sep 29.

38.

ERK/p44p42 mitogen-activated protein kinase mediates EGF-stimulated proliferation of conjunctival goblet cells in culture.

Shatos MA, Gu J, Hodges RR, Lashkari K, Dartt DA.

Invest Ophthalmol Vis Sci. 2008 Aug;49(8):3351-9. doi: 10.1167/iovs.08-1677. Epub 2008 Apr 17.

39.

Presence of EGF growth factor ligands and their effects on cultured rat conjunctival goblet cell proliferation.

Gu J, Chen L, Shatos MA, Rios JD, Gulati A, Hodges RR, Dartt DA.

Exp Eye Res. 2008 Feb;86(2):322-34. Epub 2007 Nov 17.

40.

Effect of protein kinase C and Ca(2+) on p42/p44 MAPK, Pyk2, and Src activation in rat conjunctival goblet cells.

Hodges RR, Horikawa Y, Rios JD, Shatos MA, Dartt DA.

Exp Eye Res. 2007 Dec;85(6):836-44. Epub 2007 Sep 2.

41.

Role of cAMP inhibition of p44/p42 mitogen-activated protein kinase in potentiation of protein secretion in rat lacrimal gland.

Funaki C, Hodges RR, Dartt DA.

Am J Physiol Cell Physiol. 2007 Nov;293(5):C1551-60. Epub 2007 Aug 8.

42.

Role of neurotrophins and neurotrophin receptors in rat conjunctival goblet cell secretion and proliferation.

Ríos JD, Ghinelli E, Gu J, Hodges RR, Dartt DA.

Invest Ophthalmol Vis Sci. 2007 Apr;48(4):1543-51.

PMID:
17389483
43.

Lymphocytic infiltration and goblet cell marker alteration in the conjunctiva of the MRL/MpJ-Fas(lpr) mouse model of Sjögren's syndrome.

Diebold Y, Chen LL, Tepavcevic V, Ferdman D, Hodges RR, Dartt DA.

Exp Eye Res. 2007 Mar;84(3):500-12. Epub 2007 Jan 17.

PMID:
17208228
44.

Roles of protein kinase C, Ca2+, Pyk2, and c-Src in agonist activation of rat lacrimal gland p42/p44 MAPK.

Hodges RR, Rios JD, Vrouvlianis J, Ota I, Zoukhri D, Dartt DA.

Invest Ophthalmol Vis Sci. 2006 Aug;47(8):3352-9.

PMID:
16877402
45.

Effects of alpha1D-adrenergic receptors on shedding of biologically active EGF in freshly isolated lacrimal gland epithelial cells.

Chen L, Hodges RR, Funaki C, Zoukhri D, Gaivin RJ, Perez DM, Dartt DA.

Am J Physiol Cell Physiol. 2006 Nov;291(5):C946-56. Epub 2006 Jun 7.

46.

Nitric oxide and cGMP mediate alpha1D-adrenergic receptor-Stimulated protein secretion and p42/p44 MAPK activation in rat lacrimal gland.

Hodges RR, Shatos MA, Tarko RS, Vrouvlianis J, Gu J, Dartt DA.

Invest Ophthalmol Vis Sci. 2005 Aug;46(8):2781-9.

47.

Age-dependent alterations in mouse exorbital lacrimal gland structure, innervation and secretory response.

Ríos JD, Horikawa Y, Chen LL, Kublin CL, Hodges RR, Dartt DA, Zoukhri D.

Exp Eye Res. 2005 Apr;80(4):477-91.

48.

Differential effects of the EGF family of growth factors on protein secretion, MAPK activation, and intracellular calcium concentration in rat lacrimal gland.

Chen LL, Johansson JK, Hodges RR, Zoukhri D, Ghinelli E, Rios JD, Dartt DA.

Exp Eye Res. 2005 Mar;80(3):379-89.

PMID:
15721620
49.

Effect of overexpression of constitutively active PKCalpha on rat lacrimal gland protein secretion.

Hodges RR, Raddassi I, Zoukhri D, Toker A, Kazlauskas A, Dartt DA.

Invest Ophthalmol Vis Sci. 2004 Nov;45(11):3974-81.

PMID:
15505044
50.

Regulatory pathways in lacrimal gland epithelium.

Hodges RR, Dartt DA.

Int Rev Cytol. 2003;231:129-96. Review.

PMID:
14713005

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