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Items: 21

1.

A targeted mass spectrometry strategy for developing proteomic biomarkers: a case study of epithelial ovarian cancer.

Huttenhain R, Choi M, Martin de la Fuente L, Oehl K, Chang CY, Zimmermann AK, Malander S, Olsson H, Surinova S, Clough T, Heinzelmann-Schwarz V, Wild PJ, Dinulescu D, Niméus E, Vitek O, Aebersold R.

Mol Cell Proteomics. 2019 Jul 9. pii: mcp.RA118.001221. doi: 10.1074/mcp.RA118.001221. [Epub ahead of print]

2.

ARIH2 Is a Vif-Dependent Regulator of CUL5-Mediated APOBEC3G Degradation in HIV Infection.

Hüttenhain R, Xu J, Burton LA, Gordon DE, Hultquist JF, Johnson JR, Satkamp L, Hiatt J, Rhee DY, Baek K, Crosby DC, Frankel AD, Marson A, Harper JW, Alpi AF, Schulman BA, Gross JD, Krogan NJ.

Cell Host Microbe. 2019 Jul 10;26(1):86-99.e7. doi: 10.1016/j.chom.2019.05.008. Epub 2019 Jun 25.

PMID:
31253590
3.

Comparative Flavivirus-Host Protein Interaction Mapping Reveals Mechanisms of Dengue and Zika Virus Pathogenesis.

Shah PS, Link N, Jang GM, Sharp PP, Zhu T, Swaney DL, Johnson JR, Von Dollen J, Ramage HR, Satkamp L, Newton B, Hüttenhain R, Petit MJ, Baum T, Everitt A, Laufman O, Tassetto M, Shales M, Stevenson E, Iglesias GN, Shokat L, Tripathi S, Balasubramaniam V, Webb LG, Aguirre S, Willsey AJ, Garcia-Sastre A, Pollard KS, Cherry S, Gamarnik AV, Marazzi I, Taunton J, Fernandez-Sesma A, Bellen HJ, Andino R, Krogan NJ.

Cell. 2018 Dec 13;175(7):1931-1945.e18. doi: 10.1016/j.cell.2018.11.028.

PMID:
30550790
4.

CRL4AMBRA1 targets Elongin C for ubiquitination and degradation to modulate CRL5 signaling.

Chen SH, Jang GM, Hüttenhain R, Gordon DE, Du D, Newton BW, Johnson JR, Hiatt J, Hultquist JF, Johnson TL, Liu YL, Burton LA, Ye J, Reichermeier KM, Stroud RM, Marson A, Debnath J, Gross JD, Krogan NJ.

EMBO J. 2018 Sep 14;37(18). pii: e97508. doi: 10.15252/embj.201797508. Epub 2018 Aug 30.

PMID:
30166453
5.

The Psychiatric Cell Map Initiative: A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders.

Willsey AJ, Morris MT, Wang S, Willsey HR, Sun N, Teerikorpi N, Baum TB, Cagney G, Bender KJ, Desai TA, Srivastava D, Davis GW, Doudna J, Chang E, Sohal V, Lowenstein DH, Li H, Agard D, Keiser MJ, Shoichet B, von Zastrow M, Mucke L, Finkbeiner S, Gan L, Sestan N, Ward ME, Huttenhain R, Nowakowski TJ, Bellen HJ, Frank LM, Khokha MK, Lifton RP, Kampmann M, Ideker T, State MW, Krogan NJ.

Cell. 2018 Jul 26;174(3):505-520. doi: 10.1016/j.cell.2018.06.016. Review.

6.

Similarities and Differences of Blood N-Glycoproteins in Five Solid Carcinomas at Localized Clinical Stage Analyzed by SWATH-MS.

Sajic T, Liu Y, Arvaniti E, Surinova S, Williams EG, Schiess R, Hüttenhain R, Sethi A, Pan S, Brentnall TA, Chen R, Blattmann P, Friedrich B, Niméus E, Malander S, Omlin A, Gillessen S, Claassen M, Aebersold R.

Cell Rep. 2018 May 29;23(9):2819-2831.e5. doi: 10.1016/j.celrep.2018.04.114.

7.

An Approach to Spatiotemporally Resolve Protein Interaction Networks in Living Cells.

Lobingier BT, Hüttenhain R, Eichel K, Miller KB, Ting AY, von Zastrow M, Krogan NJ.

Cell. 2017 Apr 6;169(2):350-360.e12. doi: 10.1016/j.cell.2017.03.022.

8.

Prediction of colorectal cancer diagnosis based on circulating plasma proteins.

Surinova S, Choi M, Tao S, Schüffler PJ, Chang CY, Clough T, Vysloužil K, Khoylou M, Srovnal J, Liu Y, Matondo M, Hüttenhain R, Weisser H, Buhmann JM, Hajdúch M, Brenner H, Vitek O, Aebersold R.

EMBO Mol Med. 2015 Sep;7(9):1166-78. doi: 10.15252/emmm.201404873.

9.

Targeted peptide measurements in biology and medicine: best practices for mass spectrometry-based assay development using a fit-for-purpose approach.

Carr SA, Abbatiello SE, Ackermann BL, Borchers C, Domon B, Deutsch EW, Grant RP, Hoofnagle AN, Hüttenhain R, Koomen JM, Liebler DC, Liu T, MacLean B, Mani DR, Mansfield E, Neubert H, Paulovich AG, Reiter L, Vitek O, Aebersold R, Anderson L, Bethem R, Blonder J, Boja E, Botelho J, Boyne M, Bradshaw RA, Burlingame AL, Chan D, Keshishian H, Kuhn E, Kinsinger C, Lee JS, Lee SW, Moritz R, Oses-Prieto J, Rifai N, Ritchie J, Rodriguez H, Srinivas PR, Townsend RR, Van Eyk J, Whiteley G, Wiita A, Weintraub S.

Mol Cell Proteomics. 2014 Mar;13(3):907-17. doi: 10.1074/mcp.M113.036095. Epub 2014 Jan 17.

10.

Mass spectrometric protein maps for biomarker discovery and clinical research.

Liu Y, Hüttenhain R, Collins B, Aebersold R.

Expert Rev Mol Diagn. 2013 Nov;13(8):811-25. doi: 10.1586/14737159.2013.845089. Epub 2013 Oct 21. Review.

11.

Automated selected reaction monitoring data analysis workflow for large-scale targeted proteomic studies.

Surinova S, Hüttenhain R, Chang CY, Espona L, Vitek O, Aebersold R.

Nat Protoc. 2013 Aug;8(8):1602-19. doi: 10.1038/nprot.2013.091. Epub 2013 Jul 25.

PMID:
23887179
12.

N-glycoprotein SRMAtlas: a resource of mass spectrometric assays for N-glycosites enabling consistent and multiplexed protein quantification for clinical applications.

Hüttenhain R, Surinova S, Ossola R, Sun Z, Campbell D, Cerciello F, Schiess R, Bausch-Fluck D, Rosenberger G, Chen J, Rinner O, Kusebauch U, Hajdúch M, Moritz RL, Wollscheid B, Aebersold R.

Mol Cell Proteomics. 2013 Apr;12(4):1005-16. doi: 10.1074/mcp.O112.026617. Epub 2013 Feb 13.

13.

Quantitative measurements of N-linked glycoproteins in human plasma by SWATH-MS.

Liu Y, Hüttenhain R, Surinova S, Gillet LC, Mouritsen J, Brunner R, Navarro P, Aebersold R.

Proteomics. 2013 Apr;13(8):1247-56. doi: 10.1002/pmic.201200417. Epub 2013 Mar 11.

PMID:
23322582
14.

Reproducible quantification of cancer-associated proteins in body fluids using targeted proteomics.

Hüttenhain R, Soste M, Selevsek N, Röst H, Sethi A, Carapito C, Farrah T, Deutsch EW, Kusebauch U, Moritz RL, Niméus-Malmström E, Rinner O, Aebersold R.

Sci Transl Med. 2012 Jul 11;4(142):142ra94. doi: 10.1126/scitranslmed.3003989.

15.

Range of protein detection by selected/multiple reaction monitoring mass spectrometry in an unfractionated human cell culture lysate.

Ebhardt HA, Sabidó E, Hüttenhain R, Collins B, Aebersold R.

Proteomics. 2012 Apr;12(8):1185-93. doi: 10.1002/pmic.201100543.

PMID:
22577020
16.

PASSEL: the PeptideAtlas SRMexperiment library.

Farrah T, Deutsch EW, Kreisberg R, Sun Z, Campbell DS, Mendoza L, Kusebauch U, Brusniak MY, Hüttenhain R, Schiess R, Selevsek N, Aebersold R, Moritz RL.

Proteomics. 2012 Apr;12(8):1170-5. doi: 10.1002/pmic.201100515.

17.

Protein significance analysis in selected reaction monitoring (SRM) measurements.

Chang CY, Picotti P, Hüttenhain R, Heinzelmann-Schwarz V, Jovanovic M, Aebersold R, Vitek O.

Mol Cell Proteomics. 2012 Apr;11(4):M111.014662. doi: 10.1074/mcp.M111.014662. Epub 2011 Dec 21.

18.

mProphet: automated data processing and statistical validation for large-scale SRM experiments.

Reiter L, Rinner O, Picotti P, Hüttenhain R, Beck M, Brusniak MY, Hengartner MO, Aebersold R.

Nat Methods. 2011 May;8(5):430-5. doi: 10.1038/nmeth.1584. Epub 2011 Mar 20.

PMID:
21423193
19.

On the development of plasma protein biomarkers.

Surinova S, Schiess R, Hüttenhain R, Cerciello F, Wollscheid B, Aebersold R.

J Proteome Res. 2011 Jan 7;10(1):5-16. doi: 10.1021/pr1008515. Epub 2010 Dec 13. Review.

PMID:
21142170
20.

A combined top-down and bottom-up MS approach for the characterization of hemoglobin variants in Rhesus monkeys.

Hüttenhain R, Hess S.

Proteomics. 2010 Oct;10(20):3657-68. doi: 10.1002/pmic.201000161.

21.

Perspectives of targeted mass spectrometry for protein biomarker verification.

Hüttenhain R, Malmström J, Picotti P, Aebersold R.

Curr Opin Chem Biol. 2009 Dec;13(5-6):518-25. doi: 10.1016/j.cbpa.2009.09.014. Epub 2009 Oct 7. Review.

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