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Items: 1 to 50 of 631

1.

Antimicrobial Activity of α-Peptide/β-Peptoid Lysine-Based Peptidomimetics Against Colistin-Resistant Pseudomonas aeruginosa Isolated From Cystic Fibrosis Patients.

Molchanova N, Wang H, Hansen PR, Høiby N, Nielsen HM, Franzyk H.

Front Microbiol. 2019 Feb 20;10:275. doi: 10.3389/fmicb.2019.00275. eCollection 2019.

2.

P. aeruginosa flow-cell biofilms are enhanced by repeated phage treatments but can be eradicated by phage-ciprofloxacin combination.

Henriksen K, Rørbo N, Rybtke ML, Martinet MG, Tolker-Nielsen T, Høiby N, Middelboe M, Ciofu O.

Pathog Dis. 2019 Mar 1. pii: ftz011. doi: 10.1093/femspd/ftz011. [Epub ahead of print]

PMID:
30821815
3.

Optimization of colistin dosing regimen for cystic fibrosis patients with chronic Pseudomonas aeruginosa biofilm lung infections.

Hengzhuang W, Green K, Pressler T, Skov M, Katzenstein TL, Wu X, Høiby N.

Pediatr Pulmonol. 2019 Feb 25. doi: 10.1002/ppul.24269. [Epub ahead of print]

PMID:
30803159
4.

Hyperbaric oxygen treatment increases killing of aggregating Pseudomonas aeruginosa isolates from cystic fibrosis patients.

Møller SA, Jensen PØ, Høiby N, Ciofu O, Kragh KN, Bjarnsholt T, Kolpen M.

J Cyst Fibros. 2019 Jan 30. pii: S1569-1993(19)30011-6. doi: 10.1016/j.jcf.2019.01.005. [Epub ahead of print]

PMID:
30711384
5.

Secretory IgA-mediated immune response in saliva and early detection of Pseudomonas aeruginosa in the lower airways of pediatric cystic fibrosis patients.

Mauch RM, Rossi CL, Nolasco da Silva MT, Bianchi Aiello T, Ribeiro JD, Ribeiro AF, Høiby N, Levy CE.

Med Microbiol Immunol. 2019 Jan 31. doi: 10.1007/s00430-019-00578-w. [Epub ahead of print]

PMID:
30706137
6.

Can secretory immunoglobulin A in saliva predict a change in lung infection status in patients with cystic fibrosis? A prospective pilot study.

Alanin MC, Pressler T, Aanaes K, Ekstrøm CT, Skov M, Johansen HK, Nielsen KG, von Buchwald C, Høiby N.

Health Sci Rep. 2018 Jul 12;1(8):e52. doi: 10.1002/hsr2.52. eCollection 2018 Aug.

7.

Formation of Pseudomonas aeruginosa inhibition zone during Tobramycin disk diffusion is due to a transition from planktonic to biofilm mode of growth.

Høiby N, Henneberg KÅ, Wang H, Stavnsbjerg C, Bjarnsholt T, Ciofu O, Johansen UR, Sams T.

Int J Antimicrob Agents. 2019 Jan 4. pii: S0924-8579(18)30385-6. doi: 10.1016/j.ijantimicag.2018.12.015. [Epub ahead of print]

8.

Antibody response against Mycobacterium avium complex in cystic fibrosis patients measured by a novel IgG ELISA test.

Ravnholt C, Qvist T, Kolpen M, Pressler T, Skov M, Høiby N.

J Cyst Fibros. 2018 Nov 29. pii: S1569-1993(18)30938-X. doi: 10.1016/j.jcf.2018.11.011. [Epub ahead of print]

PMID:
30503330
9.

Adaptation of Pseudomonas aeruginosa to the chronic phenotype by mutations in the algTmucABD operon in isolates from Brazilian cystic fibrosis patients.

Candido Caçador N, Paulino da Costa Capizzani C, Gomes Monteiro Marin Torres LA, Galetti R, Ciofu O, da Costa Darini AL, Høiby N.

PLoS One. 2018 Nov 29;13(11):e0208013. doi: 10.1371/journal.pone.0208013. eCollection 2018.

10.

The importance of early diagnosis of Mycobacterium abscessus complex in patients with cystic fibrosis.

Ravnholt C, Kolpen M, Skov M, Moser C, Katzenstein TL, Pressler T, Høiby N, Qvist T.

APMIS. 2018 Dec;126(12):885-891. doi: 10.1111/apm.12903. Review.

PMID:
30456869
11.

Next generation microbiology and cystic fibrosis diagnostics: are we there yet?

Moser C, Thomsen TR, Høiby N.

Curr Opin Pulm Med. 2018 Nov;24(6):599-605. doi: 10.1097/MCP.0000000000000516.

PMID:
30074508
12.

Erratum: Chronic Pseudomonas aeruginosa biofilm infection impairs murine S100A8/A9 and neutrophil effector cytokines-implications for delayed wound closure?

Trøstrup H, Lerche CJ, Christophersen LJ, Thomsen K, Jensen PØ, Hougen HP, Høiby N, Moser C.

Pathog Dis. 2017 Nov 30;75(8). doi: 10.1093/femspd/ftx110. No abstract available.

PMID:
30052962
13.

Modelling of ciprofloxacin killing enhanced by hyperbaric oxygen treatment in Pseudomonas aeruginosa PAO1 biofilms.

Gade PAV, Olsen TB, Jensen PØ, Kolpen M, Høiby N, Henneberg KÅ, Sams T.

PLoS One. 2018 Jun 14;13(6):e0198909. doi: 10.1371/journal.pone.0198909. eCollection 2018.

14.

Evolution of Antibiotic Resistance in Biofilm and Planktonic Pseudomonas aeruginosa Populations Exposed to Subinhibitory Levels of Ciprofloxacin.

Ahmed MN, Porse A, Sommer MOA, Høiby N, Ciofu O.

Antimicrob Agents Chemother. 2018 Jul 27;62(8). pii: e00320-18. doi: 10.1128/AAC.00320-18. Print 2018 Aug.

15.

A systematic review of studies on the faecal microbiota in anorexia nervosa: future research may need to include microbiota from the small intestine.

Schwensen HF, Kan C, Treasure J, Høiby N, Sjögren M.

Eat Weight Disord. 2018 Aug;23(4):399-418. doi: 10.1007/s40519-018-0499-9. Epub 2018 Mar 14. Review.

PMID:
29542066
16.

The accessibility of topical treatment in the paranasal sinuses on operated cystic fibrosis patients assessed by scintigraphy.

Aanaes K, Alanin MC, Nielsen KG, Moller Jorgensen M, von Buchwald C, Hoiby N, Johansen HK, Johannesen HH, Mortensen J.

Rhinology. 2018 Sep 1;56(3):268-273. doi: 10.4193/Rhin17.243.

PMID:
29509830
17.

Pseudomonas aeruginosa biofilm hampers murine central wound healing by suppression of vascular epithelial growth factor.

Trøstrup H, Lerche CJ, Christophersen LJ, Thomsen K, Jensen PØ, Hougen HP, Høiby N, Moser C.

Int Wound J. 2018 Feb;15(1):123-132. doi: 10.1111/iwj.12846. Epub 2017 Nov 27.

PMID:
29178668
18.

Mechanisms of humoral immune response against Pseudomonas aeruginosa biofilm infection in cystic fibrosis.

Mauch RM, Jensen PØ, Moser C, Levy CE, Høiby N.

J Cyst Fibros. 2018 Mar;17(2):143-152. doi: 10.1016/j.jcf.2017.08.012. Epub 2017 Oct 21. Review.

PMID:
29033275
19.

IgG avidity to Pseudomonas aeruginosa over the course of chronic lung biofilm infection in cystic fibrosis.

Mauch RM, Nørregaard LL, Ciofu O, Levy CE, Høiby N.

J Cyst Fibros. 2018 May;17(3):356-359. doi: 10.1016/j.jcf.2017.09.004. Epub 2017 Oct 12.

PMID:
29032178
20.

Hyperbaric Oxygen Sensitizes Anoxic Pseudomonas aeruginosa Biofilm to Ciprofloxacin.

Kolpen M, Lerche CJ, Kragh KN, Sams T, Koren K, Jensen AS, Line L, Bjarnsholt T, Ciofu O, Moser C, Kühl M, Høiby N, Jensen PØ.

Antimicrob Agents Chemother. 2017 Oct 24;61(11). pii: e01024-17. doi: 10.1128/AAC.01024-17. Print 2017 Nov.

21.

Sinus bacteriology in patients with cystic fibrosis or primary ciliary dyskinesia: A systematic review.

Møller ME, Alanin MC, Grønhøj C, Aanæs K, Høiby N, von Buchwald C.

Am J Rhinol Allergy. 2017 Sep 1;31(5):293-298. doi: 10.2500/ajra.2017.31.4461. Review.

22.

Immune Modulating Topical S100A8/A9 Inhibits Growth of Pseudomonas aeruginosa and Mitigates Biofilm Infection in Chronic Wounds.

Trøstrup H, Lerche CJ, Christophersen L, Jensen PØ, Høiby N, Moser C.

Int J Mol Sci. 2017 Jun 26;18(7). pii: E1359. doi: 10.3390/ijms18071359.

23.

Hyperbaric oxygen therapy augments tobramycin efficacy in experimental Staphylococcus aureus endocarditis.

Lerche CJ, Christophersen LJ, Kolpen M, Nielsen PR, Trøstrup H, Thomsen K, Hyldegaard O, Bundgaard H, Jensen PØ, Høiby N, Moser C.

Int J Antimicrob Agents. 2017 Sep;50(3):406-412. doi: 10.1016/j.ijantimicag.2017.04.025. Epub 2017 Jun 29.

PMID:
28669832
24.

Chronic Pseudomonas aeruginosa biofilm infection impairs murine S100A8/A9 and neutrophil effector cytokines-implications for delayed wound closure?

Trøstrup H, Lerche CJ, Christophersen LJ, Thomsen K, Jensen PØ, Hougen HP, Høiby N, Moser C.

Pathog Dis. 2017 Sep 29;75(7). doi: 10.1093/femspd/ftx068. Erratum in: Pathog Dis. 2017 Nov 30;75(8):.

PMID:
28645160
25.

Secretory IgA response against Pseudomonas aeruginosa in the upper airways and the link with chronic lung infection in cystic fibrosis.

Mauch RM, Rossi CL, Aiello TB, Ribeiro JD, Ribeiro AF, Høiby N, Levy CE.

Pathog Dis. 2017 Aug 31;75(6). doi: 10.1093/femspd/ftx069.

PMID:
28645157
26.

Mouse Model of Burn Wound and Infection: Thermal (Hot Air) Lesion-Induced Immunosuppression.

Calum H, Høiby N, Moser C.

Curr Protoc Mouse Biol. 2017 Jun 19;7(2):77-87. doi: 10.1002/cpmo.25.

PMID:
28628217
27.

Diagnosis of biofilm infections in cystic fibrosis patients.

Høiby N, Bjarnsholt T, Moser C, Jensen PØ, Kolpen M, Qvist T, Aanaes K, Pressler T, Skov M, Ciofu O.

APMIS. 2017 Apr;125(4):339-343. doi: 10.1111/apm.12689. Review.

PMID:
28407432
28.

Chronic urinary tract infections in patients with spinal cord lesions - biofilm infection with need for long-term antibiotic treatment.

Tofte N, Nielsen AC, Trøstrup H, Andersen CB, Von Linstow M, Hansen B, Biering-Sørensen F, Høiby N, Moser C.

APMIS. 2017 Apr;125(4):385-391. doi: 10.1111/apm.12685. Review.

PMID:
28407430
29.

Biofilms and host response - helpful or harmful.

Moser C, Pedersen HT, Lerche CJ, Kolpen M, Line L, Thomsen K, Høiby N, Jensen PØ.

APMIS. 2017 Apr;125(4):320-338. doi: 10.1111/apm.12674. Review.

PMID:
28407429
30.

A short history of microbial biofilms and biofilm infections.

Høiby N.

APMIS. 2017 Apr;125(4):272-275. doi: 10.1111/apm.12686. Review.

PMID:
28407426
31.

Experimental Pseudomonas aeruginosa mediated rhino sinusitis in mink.

Kirkeby S, Hammer AS, Høiby N, Salomonsen CM.

Int J Pediatr Otorhinolaryngol. 2017 May;96:156-163. doi: 10.1016/j.ijporl.2016.12.037. Epub 2016 Dec 27.

PMID:
28302328
32.

Individual pharmacokinetic variation leads to underdosing of ciprofloxacin in some cystic fibrosis patients.

Schultz AN, Høiby N, Nielsen XC, Pressler T, Dalhoff K, Duno M, Buchard A, Johansen HK, Wang H, Dalbøge CS.

Pediatr Pulmonol. 2017 Mar;52(3):319-323. doi: 10.1002/ppul.23638. Epub 2016 Nov 4.

PMID:
28221736
33.

Sinus surgery can improve quality of life, lung infections, and lung function in patients with primary ciliary dyskinesia.

Alanin MC, Aanaes K, Høiby N, Pressler T, Skov M, Nielsen KG, Johansen HK, von Buchwald C.

Int Forum Allergy Rhinol. 2017 Mar;7(3):240-247. doi: 10.1002/alr.21873. Epub 2016 Nov 23.

PMID:
27879058
34.

Phenotypic shift in Pseudomonas aeruginosa populations from cystic fibrosis lungs after 2-week antipseudomonal treatment.

Fernández-Barat L, Ciofu O, Kragh KN, Pressler T, Johansen U, Motos A, Torres A, Hoiby N.

J Cyst Fibros. 2017 Mar;16(2):222-229. doi: 10.1016/j.jcf.2016.08.005. Epub 2016 Sep 17.

35.

Evaluation of a bovine antibody test for diagnosing Mycobacterium avium complex in patients with cystic fibrosis.

Qvist T, Pressler T, Katzenstein TL, Høiby N, Collins MT.

Pediatr Pulmonol. 2017 Jan;52(1):34-40. doi: 10.1002/ppul.23608. Epub 2016 Sep 20.

PMID:
27648735
36.

The dlt genes play a role in antimicrobial tolerance of Streptococcus mutans biofilms.

Nilsson M, Rybtke M, Givskov M, Høiby N, Twetman S, Tolker-Nielsen T.

Int J Antimicrob Agents. 2016 Sep;48(3):298-304. doi: 10.1016/j.ijantimicag.2016.06.019. Epub 2016 Jul 28.

PMID:
27502751
37.

Bacterial evolution in PCD and CF patients follows the same mutational steps.

Sommer LM, Alanin MC, Marvig RL, Nielsen KG, Høiby N, von Buchwald C, Molin S, Johansen HK.

Sci Rep. 2016 Jun 28;6:28732. doi: 10.1038/srep28732.

38.

Sinus surgery postpones chronic Gram-negative lung infection: cohort study of 106 patients with cystic fibrosis.

Alanin MC, Aanaes K, Høiby N, Pressler T, Skov M, Nielsen KG, Taylor-Robinson D, Waldmann E, Krogh Johansen H, von Buchwald C.

Rhinology. 2016 Sep;54(3):206-13. doi: 10.4193/Rhin15.347.

PMID:
27116399
39.

Diffusion Retardation by Binding of Tobramycin in an Alginate Biofilm Model.

Cao B, Christophersen L, Kolpen M, Jensen PØ, Sneppen K, Høiby N, Moser C, Sams T.

PLoS One. 2016 Apr 21;11(4):e0153616. doi: 10.1371/journal.pone.0153616. eCollection 2016.

40.

S100A8/A9 is an important host defence mediator in neuropathic foot ulcers in patients with type 2 diabetes mellitus.

Trøstrup H, Holstein P, Christophersen L, Jørgensen B, Karlsmark T, Høiby N, Moser C, Ågren MS.

Arch Dermatol Res. 2016 Jul;308(5):347-55. doi: 10.1007/s00403-016-1646-7. Epub 2016 Apr 15.

PMID:
27084691
41.

[Augmented renal clearance of antibiotics may lead to inadequate dosings for patients with sepsis].

Moser C, Hartvig T, Schierbeck J, Høiby N.

Ugeskr Laeger. 2016 Mar 14;178(11):V05150426. Review. Danish.

PMID:
27032308
42.

Activation of pulmonary and lymph node dendritic cells during chronic Pseudomonas aeruginosa lung infection in mice.

Damlund DS, Christophersen L, Jensen PØ, Alhede M, Høiby N, Moser C.

APMIS. 2016 Jun;124(6):500-7. doi: 10.1111/apm.12530. Epub 2016 Mar 24.

PMID:
27009697
43.

The phenotypic evolution of Pseudomonas aeruginosa populations changes in the presence of subinhibitory concentrations of ciprofloxacin.

Wassermann T, Meinike Jørgensen K, Ivanyshyn K, Bjarnsholt T, Khademi SM, Jelsbak L, Høiby N, Ciofu O.

Microbiology. 2016 May;162(5):865-75. doi: 10.1099/mic.0.000273. Epub 2016 Mar 7.

PMID:
26953154
44.

Genome Sequence of Pseudomonas aeruginosa Strain DK1-NH57388A, a Stable Mucoid Cystic Fibrosis Isolate.

Norman A, Ciofu O, Amador CI, Høiby N, Jelsbak L.

Genome Announc. 2016 Feb 25;4(1). pii: e00008-16. doi: 10.1128/genomeA.00008-16.

45.

Anti-Pseudomonas aeruginosa IgY antibodies promote bacterial opsonization and augment the phagocytic activity of polymorphonuclear neutrophils.

Thomsen K, Christophersen L, Jensen PØ, Bjarnsholt T, Moser C, Høiby N.

Hum Vaccin Immunother. 2016 Jul 2;12(7):1690-9. doi: 10.1080/21645515.2016.1145848. Epub 2016 Feb 22.

46.

OligoG CF-5/20 Disruption of Mucoid Pseudomonas aeruginosa Biofilm in a Murine Lung Infection Model.

Hengzhuang W, Song Z, Ciofu O, Onsøyen E, Rye PD, Høiby N.

Antimicrob Agents Chemother. 2016 Apr 22;60(5):2620-6. doi: 10.1128/AAC.01721-15. Print 2016 May.

47.

The phagocytic fitness of leucopatches may impact the healing of chronic wounds.

Thomsen K, Trøstrup H, Christophersen L, Lundquist R, Høiby N, Moser C.

Clin Exp Immunol. 2016 Jun;184(3):368-77. doi: 10.1111/cei.12773. Epub 2016 Mar 23.

48.

Reinforcement of the bactericidal effect of ciprofloxacin on Pseudomonas aeruginosa biofilm by hyperbaric oxygen treatment.

Kolpen M, Mousavi N, Sams T, Bjarnsholt T, Ciofu O, Moser C, Kühl M, Høiby N, Jensen PØ.

Int J Antimicrob Agents. 2016 Feb;47(2):163-7. doi: 10.1016/j.ijantimicag.2015.12.005. Epub 2015 Dec 29.

PMID:
26774522
49.

New technology markedly improves hand-hygiene performance among healthcare workers after restroom visits.

Møller-Sørensen H, Korshin A, Mogensen T, Høiby N.

J Hosp Infect. 2016 Apr;92(4):337-9. doi: 10.1016/j.jhin.2015.09.012. Epub 2015 Oct 22.

PMID:
26597634
50.

Chronic pulmonary disease with Mycobacterium abscessus complex is a biofilm infection.

Qvist T, Eickhardt S, Kragh KN, Andersen CB, Iversen M, Høiby N, Bjarnsholt T.

Eur Respir J. 2015 Dec;46(6):1823-6. doi: 10.1183/13993003.01102-2015. Epub 2015 Oct 22. No abstract available.

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