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Items: 18

1.

The RNA-Protein Interactome of Differentiated Kidney Tubular Epithelial Cells.

Ignarski M, Rill C, Kaiser RWJ, Kaldirim M, Neuhaus R, Esmaillie R, Li X, Klein C, Bohl K, Petersen M, Frese CK, Höhne M, Atanassov I, Rinschen MM, Höpker K, Schermer B, Benzing T, Dieterich C, Fabretti F, Müller RU.

J Am Soc Nephrol. 2019 Mar 13. pii: ASN.2018090914. doi: 10.1681/ASN.2018090914. [Epub ahead of print]

PMID:
30867249
2.

Inactivation of Apoptosis Antagonizing Transcription Factor in tubular epithelial cells induces accumulation of DNA damage and nephronophthisis.

Jain M, Kaiser RWJ, Bohl K, Hoehne M, Göbel H, Bartram MP, Habbig S, Müller RU, Fogo AB, Benzing T, Schermer B, Höpker K, Slaats GG.

Kidney Int. 2019 Feb 12. pii: S0085-2538(18)30894-9. doi: 10.1016/j.kint.2018.10.034. [Epub ahead of print]

PMID:
30770218
3.

AATF suppresses apoptosis, promotes proliferation and is critical for Kras-driven lung cancer.

Welcker D, Jain M, Khurshid S, Jokić M, Höhne M, Schmitt A, Frommolt P, Niessen CM, Spiro J, Persigehl T, Wittersheim M, Büttner R, Fanciulli M, Schermer B, Reinhardt HC, Benzing T, Höpker K.

Oncogene. 2018 Mar;37(11):1503-1518. doi: 10.1038/s41388-017-0054-6. Epub 2018 Jan 11.

PMID:
29321668
4.

Che-1 modulates the decision between cell cycle arrest and apoptosis by its binding to p53.

Desantis A, Bruno T, Catena V, De Nicola F, Goeman F, Iezzi S, Sorino C, Gentileschi MP, Germoni S, Monteleone V, Pellegrino M, Kann M, De Meo PD, Pallocca M, Höpker K, Moretti F, Mattei E, Reinhardt HC, Floridi A, Passananti C, Benzing T, Blandino G, Fanciulli M.

Cell Death Dis. 2015 May 21;6:e1764. doi: 10.1038/cddis.2015.117.

5.

Dysregulated autophagy contributes to podocyte damage in Fabry's disease.

Liebau MC, Braun F, Höpker K, Weitbrecht C, Bartels V, Müller RU, Brodesser S, Saleem MA, Benzing T, Schermer B, Cybulla M, Kurschat CE.

PLoS One. 2013 May 17;8(5):e63506. doi: 10.1371/journal.pone.0063506. Print 2013.

6.

[p53-regulating pathways as targets for personalized cancer therapy].

Höpker K, Reinhardt HC.

Dtsch Med Wochenschr. 2013 Jan;138(3):82-6. doi: 10.1055/s-0032-1327380. Epub 2013 Jan 8. Review. German.

PMID:
23299342
7.

Putting the brakes on p53-driven apoptosis.

Höpker K, Hagmann H, Khurshid S, Chen S, Schermer B, Benzing T, Reinhardt HC.

Cell Cycle. 2012 Nov 15;11(22):4122-8. doi: 10.4161/cc.21997. Epub 2012 Sep 14.

8.

Posttranscriptional regulation of gene expression-adding another layer of complexity to the DNA damage response.

Boucas J, Riabinska A, Jokic M, Herter-Sprie GS, Chen S, Höpker K, Reinhardt HC.

Front Genet. 2012 Aug 25;3:159. doi: 10.3389/fgene.2012.00159. eCollection 2012.

9.

AATF/Che-1 acts as a phosphorylation-dependent molecular modulator to repress p53-driven apoptosis.

Höpker K, Hagmann H, Khurshid S, Chen S, Hasskamp P, Seeger-Nukpezah T, Schilberg K, Heukamp L, Lamkemeyer T, Sos ML, Thomas RK, Lowery D, Roels F, Fischer M, Liebau MC, Resch U, Kisner T, Röther F, Bartram MP, Müller RU, Fabretti F, Kurschat P, Schumacher B, Gaestel M, Medema RH, Yaffe MB, Schermer B, Reinhardt HC, Benzing T.

EMBO J. 2012 Oct 17;31(20):3961-75. doi: 10.1038/emboj.2012.236. Epub 2012 Aug 21.

10.

The centrosomal kinase Plk1 localizes to the transition zone of primary cilia and induces phosphorylation of nephrocystin-1.

Seeger-Nukpezah T, Liebau MC, Höpker K, Lamkemeyer T, Benzing T, Golemis EA, Schermer B.

PLoS One. 2012;7(6):e38838. doi: 10.1371/journal.pone.0038838. Epub 2012 Jun 11.

11.

[Synthetic lethality as a new concept for the treatment of cancer].

Herter-Sprie GS, Chen S, Höpker K, Reinhardt HC.

Dtsch Med Wochenschr. 2011 Jul;136(30):1526-30. doi: 10.1055/s-0031-1281549. Epub 2011 Jul 25. Review. German.

PMID:
21789751
12.

Nephrocystin-4 regulates Pyk2-induced tyrosine phosphorylation of nephrocystin-1 to control targeting to monocilia.

Liebau MC, Höpker K, Müller RU, Schmedding I, Zank S, Schairer B, Fabretti F, Höhne M, Bartram MP, Dafinger C, Hackl M, Burst V, Habbig S, Zentgraf H, Blaukat A, Walz G, Benzing T, Schermer B.

J Biol Chem. 2011 Apr 22;286(16):14237-45. doi: 10.1074/jbc.M110.165464. Epub 2011 Feb 28.

13.

Atypical Alport syndrome associated with a novel COL4A5 mutation.

Höpker K, Liebau MC, Friederichsohn C, Waldherr R, Benzing T.

Clin Nephrol. 2009 Mar;71(3):321-5. Erratum in: Clin Nephrol. 2010 Feb;73(2):172.

PMID:
19281745
14.

Phosphorylation by casein kinase 2 induces PACS-1 binding of nephrocystin and targeting to cilia.

Schermer B, Höpker K, Omran H, Ghenoiu C, Fliegauf M, Fekete A, Horvath J, Köttgen M, Hackl M, Zschiedrich S, Huber TB, Kramer-Zucker A, Zentgraf H, Blaukat A, Walz G, Benzing T.

EMBO J. 2005 Dec 21;24(24):4415-24. Epub 2005 Nov 24.

16.

Trafficking of TRPP2 by PACS proteins represents a novel mechanism of ion channel regulation.

Köttgen M, Benzing T, Simmen T, Tauber R, Buchholz B, Feliciangeli S, Huber TB, Schermer B, Kramer-Zucker A, Höpker K, Simmen KC, Tschucke CC, Sandford R, Kim E, Thomas G, Walz G.

EMBO J. 2005 Feb 23;24(4):705-16. Epub 2005 Feb 3.

18.

Nephrocystin interacts with Pyk2, p130(Cas), and tensin and triggers phosphorylation of Pyk2.

Benzing T, Gerke P, Höpker K, Hildebrandt F, Kim E, Walz G.

Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9784-9. Epub 2001 Aug 7.

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