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Items: 8

1.

VKORC1 and VKORC1L1 have distinctly different oral anticoagulant dose-response characteristics and binding sites.

Czogalla KJ, Liphardt K, Höning K, Hornung V, Biswas A, Watzka M, Oldenburg J.

Blood Adv. 2018 Mar 27;2(6):691-702. doi: 10.1182/bloodadvances.2017006775.

2.

Frequently used bioinformatics tools overestimate the damaging effect of allelic variants.

Andersen LL, Terczyńska-Dyla E, Mørk N, Scavenius C, Enghild JJ, Höning K, Hornung V, Christiansen M, Mogensen TH, Hartmann R.

Genes Immun. 2019 Jan;20(1):10-22. doi: 10.1038/s41435-017-0002-z. Epub 2017 Dec 4.

PMID:
29217828
3.

Warfarin and vitamin K compete for binding to Phe55 in human VKOR.

Czogalla KJ, Biswas A, Höning K, Hornung V, Liphardt K, Watzka M, Oldenburg J.

Nat Struct Mol Biol. 2017 Jan;24(1):77-85. doi: 10.1038/nsmb.3338. Epub 2016 Dec 12.

PMID:
27941861
4.

CRISPaint allows modular base-specific gene tagging using a ligase-4-dependent mechanism.

Schmid-Burgk JL, Höning K, Ebert TS, Hornung V.

Nat Commun. 2016 Jul 28;7:12338. doi: 10.1038/ncomms12338.

5.

Cre-dependent DNA recombination activates a STING-dependent innate immune response.

Pépin G, Ferrand J, Höning K, Jayasekara WS, Cain JE, Behlke MA, Gough DJ, G Williams BR, Hornung V, Gantier MP.

Nucleic Acids Res. 2016 Jun 20;44(11):5356-64. doi: 10.1093/nar/gkw405. Epub 2016 May 10.

6.

Functional IRF3 deficiency in a patient with herpes simplex encephalitis.

Andersen LL, Mørk N, Reinert LS, Kofod-Olsen E, Narita R, Jørgensen SE, Skipper KA, Höning K, Gad HH, Østergaard L, Ørntoft TF, Hornung V, Paludan SR, Mikkelsen JG, Fujita T, Christiansen M, Hartmann R, Mogensen TH.

J Exp Med. 2015 Aug 24;212(9):1371-9. doi: 10.1084/jem.20142274. Epub 2015 Jul 27.

7.

Cytosolic RNA:DNA hybrids activate the cGAS-STING axis.

Mankan AK, Schmidt T, Chauhan D, Goldeck M, Höning K, Gaidt M, Kubarenko AV, Andreeva L, Hopfner KP, Hornung V.

EMBO J. 2014 Dec 17;33(24):2937-46. doi: 10.15252/embj.201488726. Epub 2014 Nov 25.

8.

A ligation-independent cloning technique for high-throughput assembly of transcription activator–like effector genes.

Schmid-Burgk JL, Schmidt T, Kaiser V, Höning K, Hornung V.

Nat Biotechnol. 2013 Jan;31(1):76-81.

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