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Items: 1 to 50 of 169

1.

A protein-RNA interaction atlas of the ribosome biogenesis factor AATF.

Kaiser RWJ, Ignarski M, Van Nostrand EL, Frese CK, Jain M, Cukoski S, Heinen H, Schaechter M, Seufert L, Bunte K, Frommolt P, Keller P, Helm M, Bohl K, Höhne M, Schermer B, Benzing T, Höpker K, Dieterich C, Yeo GW, Müller RU, Fabretti F.

Sci Rep. 2019 Jul 30;9(1):11071. doi: 10.1038/s41598-019-47552-3.

2.

Combining Photo-Organo Redox- and Enzyme Catalysis Facilitates Asymmetric C-H Bond Functionalization.

Zhang W, Fueyo EF, Hollmann F, Martin LL, Pesic M, Wardenga R, Höhne M, Schmidt S.

European J Org Chem. 2019 Jan 10;2019(1):80-84. doi: 10.1002/ejoc.201801692. Epub 2018 Dec 18.

3.

The RNA-Protein Interactome of Differentiated Kidney Tubular Epithelial Cells.

Ignarski M, Rill C, Kaiser RWJ, Kaldirim M, Neuhaus R, Esmaillie R, Li X, Klein C, Bohl K, Petersen M, Frese CK, Höhne M, Atanassov I, Rinschen MM, Höpker K, Schermer B, Benzing T, Dieterich C, Fabretti F, Müller RU.

J Am Soc Nephrol. 2019 Apr;30(4):564-576. doi: 10.1681/ASN.2018090914. Epub 2019 Mar 13.

PMID:
30867249
4.

Response of the Circadian Clock and Diel Starch Turnover to One Day of Low Light or Low CO2.

Moraes TA, Mengin V, Annunziata MG, Encke B, Krohn N, Höhne M, Stitt M.

Plant Physiol. 2019 Apr;179(4):1457-1478. doi: 10.1104/pp.18.01418. Epub 2019 Jan 22.

5.

Viral gastroenteritis among children of 0-5 years in Nigeria: Characterization of the first Nigerian aichivirus, recombinant noroviruses and detection of a zoonotic astrovirus.

Japhet MO, Famurewa O, Adesina OA, Opaleye OO, Wang B, Höhne M, Bock CT, Mas Marques A, Niendorf S.

J Clin Virol. 2019 Feb;111:4-11. doi: 10.1016/j.jcv.2018.12.004. Epub 2018 Dec 17.

PMID:
30580015
6.

The proteome microenvironment determines the protective effect of preconditioning in cisplatin-induced acute kidney injury.

Späth MR, Bartram MP, Palacio-Escat N, Hoyer KJR, Debes C, Demir F, Schroeter CB, Mandel AM, Grundmann F, Ciarimboli G, Beyer A, Kizhakkedathu JN, Brodesser S, Göbel H, Becker JU, Benzing T, Schermer B, Höhne M, Burst V, Saez-Rodriguez J, Huesgen PF, Müller RU, Rinschen MM.

Kidney Int. 2019 Feb;95(2):333-349. doi: 10.1016/j.kint.2018.08.037. Epub 2018 Dec 3.

PMID:
30522767
7.

Effects of microcompartmentation on flux distribution and metabolic pools in Chlamydomonas reinhardtii chloroplasts.

Küken A, Sommer F, Yaneva-Roder L, Mackinder LC, Höhne M, Geimer S, Jonikas MC, Schroda M, Stitt M, Nikoloski Z, Mettler-Altmann T.

Elife. 2018 Oct 11;7. pii: e37960. doi: 10.7554/eLife.37960.

8.

Molecular recognition of the beta-glucans laminarin and pustulan by a SusD-like glycan-binding protein of a marine Bacteroidetes.

Mystkowska AA, Robb C, Vidal-Melgosa S, Vanni C, Fernandez-Guerra A, Höhne M, Hehemann JH.

FEBS J. 2018 Dec;285(23):4465-4481. doi: 10.1111/febs.14674. Epub 2018 Oct 28.

PMID:
30300505
9.

Multiple circadian clock outputs regulate diel turnover of carbon and nitrogen reserves.

Flis A, Mengin V, Ivakov AA, Mugford ST, Hubberten HM, Encke B, Krohn N, Höhne M, Feil R, Hoefgen R, Lunn JE, Millar AJ, Smith AM, Sulpice R, Stitt M.

Plant Cell Environ. 2019 Feb;42(2):549-573. doi: 10.1111/pce.13440.

PMID:
30184255
10.

Targeted deletion of the AAA-ATPase Ruvbl1 in mice disrupts ciliary integrity and causes renal disease and hydrocephalus.

Dafinger C, Rinschen MM, Borgal L, Ehrenberg C, Basten SG, Franke M, Höhne M, Rauh M, Göbel H, Bloch W, Wunderlich FT, Peters DJM, Tasche D, Mishra T, Habbig S, Dötsch J, Müller RU, Brüning JC, Persigehl T, Giles RH, Benzing T, Schermer B, Liebau MC.

Exp Mol Med. 2018 Jun 28;50(6):75. doi: 10.1038/s12276-018-0108-z.

11.

Single-nephron proteomes connect morphology and function in proteinuric kidney disease.

Höhne M, Frese CK, Grahammer F, Dafinger C, Ciarimboli G, Butt L, Binz J, Hackl MJ, Rahmatollahi M, Kann M, Schneider S, Altintas MM, Schermer B, Reinheckel T, Göbel H, Reiser J, Huber TB, Kramann R, Seeger-Nukpezah T, Liebau MC, Beck BB, Benzing T, Beyer A, Rinschen MM.

Kidney Int. 2018 Jun;93(6):1308-1319. doi: 10.1016/j.kint.2017.12.012. Epub 2018 Mar 9.

PMID:
29530281
12.

Co-circulation of classic and novel astrovirus strains in patients with acute gastroenteritis in Germany.

Jacobsen S, Höhne M, Marques AM, Beslmüller K, Bock CT, Niendorf S.

J Infect. 2018 May;76(5):457-464. doi: 10.1016/j.jinf.2018.02.006. Epub 2018 Feb 14.

PMID:
29454018
13.

AATF suppresses apoptosis, promotes proliferation and is critical for Kras-driven lung cancer.

Welcker D, Jain M, Khurshid S, Jokić M, Höhne M, Schmitt A, Frommolt P, Niessen CM, Spiro J, Persigehl T, Wittersheim M, Büttner R, Fanciulli M, Schermer B, Reinhardt HC, Benzing T, Höpker K.

Oncogene. 2018 Mar;37(11):1503-1518. doi: 10.1038/s41388-017-0054-6. Epub 2018 Jan 11.

PMID:
29321668
14.

Solid-Phase Agar Plate Assay for Screening Amine Transaminases.

Weiß MS, Bornscheuer UT, Höhne M.

Methods Mol Biol. 2018;1685:283-296. doi: 10.1007/978-1-4939-7366-8_17.

PMID:
29086316
15.

Photometric Characterization of the Reductive Amination Scope of the Imine Reductases from Streptomyces tsukubaensis and Streptomyces ipomoeae.

Matzel P, Krautschick L, Höhne M.

Chembiochem. 2017 Oct 18;18(20):2022-2027. doi: 10.1002/cbic.201700257. Epub 2017 Sep 18.

PMID:
28833946
16.

Magnetic resonance T2 mapping and diffusion-weighted imaging for early detection of cystogenesis and response to therapy in a mouse model of polycystic kidney disease.

Franke M, Baeßler B, Vechtel J, Dafinger C, Höhne M, Borgal L, Göbel H, Koerber F, Maintz D, Benzing T, Schermer B, Persigehl T.

Kidney Int. 2017 Dec;92(6):1544-1554. doi: 10.1016/j.kint.2017.05.024. Epub 2017 Jul 26.

PMID:
28754558
17.

N-Degradomic Analysis Reveals a Proteolytic Network Processing the Podocyte Cytoskeleton.

Rinschen MM, Hoppe AK, Grahammer F, Kann M, Völker LA, Schurek EM, Binz J, Höhne M, Demir F, Malisic M, Huber TB, Kurschat C, Kizhakkedathu JN, Schermer B, Huesgen PF, Benzing T.

J Am Soc Nephrol. 2017 Oct;28(10):2867-2878. doi: 10.1681/ASN.2016101119. Epub 2017 Jul 19.

18.

The ciliary membrane-associated proteome reveals actin-binding proteins as key components of cilia.

Kohli P, Höhne M, Jüngst C, Bertsch S, Ebert LK, Schauss AC, Benzing T, Rinschen MM, Schermer B.

EMBO Rep. 2017 Sep;18(9):1521-1535. doi: 10.15252/embr.201643846. Epub 2017 Jul 14.

19.

YAP-mediated mechanotransduction determines the podocyte's response to damage.

Rinschen MM, Grahammer F, Hoppe AK, Kohli P, Hagmann H, Kretz O, Bertsch S, Höhne M, Göbel H, Bartram MP, Gandhirajan RK, Krüger M, Brinkkoetter PT, Huber TB, Kann M, Wickström SA, Benzing T, Schermer B.

Sci Signal. 2017 Apr 11;10(474). pii: eaaf8165. doi: 10.1126/scisignal.aaf8165.

PMID:
28400537
20.

A functional variant in NEPH3 gene confers high risk of renal failure in primary hematuric glomerulopathies. Evidence for predisposition to microalbuminuria in the general population.

Voskarides K, Stefanou C, Pieri M, Demosthenous P, Felekkis K, Arsali M, Athanasiou Y, Xydakis D, Stylianou K, Daphnis E, Goulielmos G, Loizou P, Savige J, Höhne M, Völker LA, Benzing T, Maxwell PH, Gale DP, Gorski M, Böger C, Kollerits B, Kronenberg F, Paulweber B, Zavros M, Pierides A, Deltas C.

PLoS One. 2017 Mar 23;12(3):e0174274. doi: 10.1371/journal.pone.0174274. eCollection 2017.

21.

Construction of a viral T2A-peptide based knock-in mouse model for enhanced Cre recombinase activity and fluorescent labeling of podocytes.

Koehler S, Brähler S, Braun F, Hagmann H, Rinschen MM, Späth MR, Höhne M, Wunderlich FT, Schermer B, Benzing T, Brinkkoetter PT.

Kidney Int. 2017 Jun;91(6):1510-1517. doi: 10.1016/j.kint.2016.12.011. Epub 2017 Feb 7.

PMID:
28187984
22.

Steep rise in norovirus cases and emergence of a new recombinant strain GII.P16-GII.2, Germany, winter 2016.

Niendorf S, Jacobsen S, Faber M, Eis-Hübinger AM, Hofmann J, Zimmermann O, Höhne M, Bock CT.

Euro Surveill. 2017 Jan 26;22(4). pii: 30447. doi: 10.2807/1560-7917.ES.2017.22.4.30447.

23.

Selective Reductions of N,N-Bis{chloro(aryl)-phosphino}-amines Yielding Three-, Five-, Six-, and Eight-Membered Cyclic Azaphosphanes.

Höhne M, Joksch M, Konieczny K, Müller BH, Spannenberg A, Peulecke N, Rosenthal U.

Chemistry. 2017 Mar 28;23(18):4298-4309. doi: 10.1002/chem.201605836. Epub 2017 Feb 14.

PMID:
28105660
24.

Structural Basis for Phospholyase Activity of a Class III Transaminase Homologue.

Cuetos A, Steffen-Munsberg F, Mangas Sanchez J, Frese A, Bornscheuer UT, Höhne M, Grogan G.

Chembiochem. 2016 Dec 14;17(24):2308-2311. doi: 10.1002/cbic.201600482. Epub 2016 Oct 31.

PMID:
27709756
25.

Single and Transient Ca2+ Peaks in Podocytes do not induce Changes in Glomerular Filtration and Perfusion.

Koehler S, Brähler S, Kuczkowski A, Binz J, Hackl MJ, Hagmann H, Höhne M, Vogt MC, Wunderlich CM, Wunderlich FT, Schweda F, Schermer B, Benzing T, Brinkkoetter PT.

Sci Rep. 2016 Oct 19;6:35400. doi: 10.1038/srep35400.

26.

Prediction of successful memory encoding based on single-trial rhinal and hippocampal phase information.

Höhne M, Jahanbekam A, Bauckhage C, Axmacher N, Fell J.

Neuroimage. 2016 Oct 1;139:127-135. doi: 10.1016/j.neuroimage.2016.06.021. Epub 2016 Jun 14.

PMID:
27311642
27.

Infection with the Persistent Murine Norovirus Strain MNV-S99 Suppresses IFN-Beta Release and Activation of Stat1 In Vitro.

Niendorf S, Klemm U, Mas Marques A, Bock CT, Höhne M.

PLoS One. 2016 Jun 13;11(6):e0156898. doi: 10.1371/journal.pone.0156898. eCollection 2016.

28.

A NADH-accepting imine reductase variant: Immobilization and cofactor regeneration by oxidative deamination.

Gand M, Thöle C, Müller H, Brundiek H, Bashiri G, Höhne M.

J Biotechnol. 2016 Jul 20;230:11-8. doi: 10.1016/j.jbiotec.2016.05.006. Epub 2016 May 6.

PMID:
27164259
29.

Ligands with an NPNPN-framework and their application in chromium catalysed ethene tri-/tetramerization.

Peulecke N, Müller BH, Spannenberg A, Höhne M, Rosenthal U, Wöhl A, Müller W, Alqahtani A, Al Hazmi M.

Dalton Trans. 2016 Jun 7;45(21):8869-74. doi: 10.1039/c6dt01109h. Epub 2016 May 6.

PMID:
27151679
30.

Prohibitin-2 Depletion Unravels Extra-Mitochondrial Functions at the Kidney Filtration Barrier.

Ising C, Bharill P, Brinkkoetter S, Brähler S, Schroeter C, Koehler S, Hagmann H, Merkwirth C, Höhne M, Müller RU, Fabretti F, Schermer B, Bloch W, Kerjaschki D, Kurschat CE, Benzing T, Brinkkoetter PT.

Am J Pathol. 2016 May;186(5):1128-39. doi: 10.1016/j.ajpath.2015.12.018.

PMID:
27105734
31.

Bacillus anthracis ω-amino acid:pyruvate transaminase employs a different mechanism for dual substrate recognition than other amine transaminases.

Steffen-Munsberg F, Matzel P, Sowa MA, Berglund P, Bornscheuer UT, Höhne M.

Appl Microbiol Biotechnol. 2016 May;100(10):4511-21. doi: 10.1007/s00253-015-7275-9. Epub 2016 Jan 21.

PMID:
26795966
32.

The ubiquitin ligase Ubr4 controls stability of podocin/MEC-2 supercomplexes.

Rinschen MM, Bharill P, Wu X, Kohli P, Reinert MJ, Kretz O, Saez I, Schermer B, Höhne M, Bartram MP, Aravamudhan S, Brooks BR, Vilchez D, Huber TB, Müller RU, Krüger M, Benzing T.

Hum Mol Genet. 2016 Apr 1;25(7):1328-44. doi: 10.1093/hmg/ddw016. Epub 2016 Jan 19.

33.

Three-layered proteomic characterization of a novel ACTN4 mutation unravels its pathogenic potential in FSGS.

Bartram MP, Habbig S, Pahmeyer C, Höhne M, Weber LT, Thiele H, Altmüller J, Kottoor N, Wenzel A, Krueger M, Schermer B, Benzing T, Rinschen MM, Beck BB.

Hum Mol Genet. 2016 Mar 15;25(6):1152-64. doi: 10.1093/hmg/ddv638. Epub 2016 Jan 5.

PMID:
26740551
34.

Brewing Painkillers: A Yeast Cell Factory for the Production of Opioids from Sugar.

Höhne M, Kabisch J.

Angew Chem Int Ed Engl. 2016 Jan 22;55(4):1248-50. doi: 10.1002/anie.201510333. Epub 2016 Jan 6. No abstract available.

PMID:
26733184
35.

Trehalose 6-phosphate coordinates organic and amino acid metabolism with carbon availability.

Figueroa CM, Feil R, Ishihara H, Watanabe M, Kölling K, Krause U, Höhne M, Encke B, Plaxton WC, Zeeman SC, Li Z, Schulze WX, Hoefgen R, Stitt M, Lunn JE.

Plant J. 2016 Feb;85(3):410-23. doi: 10.1111/tpj.13114.

36.

Alteration of the Donor/Acceptor Spectrum of the (S)-Amine Transaminase from Vibrio fluvialis.

Genz M, Vickers C, van den Bergh T, Joosten HJ, Dörr M, Höhne M, Bornscheuer UT.

Int J Mol Sci. 2015 Nov 11;16(11):26953-63. doi: 10.3390/ijms161126007.

37.

Use of sequence analysis of the P2 domain for characterization of norovirus strains causing a large multistate outbreak of norovirus gastroenteritis in Germany 2012.

Höhne M, Niendorf S, Mas Marques A, Bock CT.

Int J Med Microbiol. 2015 Oct;305(7):612-8. doi: 10.1016/j.ijmm.2015.08.010. Epub 2015 Aug 21.

PMID:
26341330
38.

Age-Dependent D-dimer Cut-off to Avoid Unnecessary CT-Exams for Ruling-out Pulmonary Embolism.

Altmann MM, Wrede CE, Peetz D, Höhne M, Stroszczynski C, Herold T.

Rofo. 2015 Sep;187(9):795-800. doi: 10.1055/s-0035-1553428. Epub 2015 Aug 26.

39.

The NF-κB essential modulator (NEMO) controls podocyte cytoskeletal dynamics independently of NF-κB.

Brähler S, Ising C, Barrera Aranda B, Höhne M, Schermer B, Benzing T, Brinkkoetter PT.

Am J Physiol Renal Physiol. 2015 Oct 1;309(7):F617-26. doi: 10.1152/ajprenal.00059.2015. Epub 2015 Aug 12.

40.

Arteriosclerosis and vascular calcification: causes, clinical assessment and therapy.

Tölle M, Reshetnik A, Schuchardt M, Höhne M, van der Giet M.

Eur J Clin Invest. 2015 Sep;45(9):976-85. doi: 10.1111/eci.12493. Epub 2015 Aug 6. Review.

PMID:
26153098
41.

Theta-gamma phase-phase coupling during working memory maintenance in the human hippocampus.

Chaieb L, Leszczynski M, Axmacher N, Höhne M, Elger CE, Fell J.

Cogn Neurosci. 2015;6(4):149-57. doi: 10.1080/17588928.2015.1058254. Epub 2015 Jun 23.

PMID:
26101947
42.

Two subtle amino Acid changes in a transaminase substantially enhance or invert enantiopreference in cascade syntheses.

Skalden L, Peters C, Dickerhoff J, Nobili A, Joosten HJ, Weisz K, Höhne M, Bornscheuer UT.

Chembiochem. 2015 May 4;16(7):1041-5. doi: 10.1002/cbic.201500074. Epub 2015 Mar 20.

PMID:
25801772
43.

Inhibition of insulin/IGF-1 receptor signaling protects from mitochondria-mediated kidney failure.

Ising C, Koehler S, Brähler S, Merkwirth C, Höhne M, Baris OR, Hagmann H, Kann M, Fabretti F, Dafinger C, Bloch W, Schermer B, Linkermann A, Brüning JC, Kurschat CE, Müller RU, Wiesner RJ, Langer T, Benzing T, Brinkkoetter PT.

EMBO Mol Med. 2015 Mar;7(3):275-87. doi: 10.15252/emmm.201404916.

44.

Bioinformatic analysis of a PLP-dependent enzyme superfamily suitable for biocatalytic applications.

Steffen-Munsberg F, Vickers C, Kohls H, Land H, Mallin H, Nobili A, Skalden L, van den Bergh T, Joosten HJ, Berglund P, Höhne M, Bornscheuer UT.

Biotechnol Adv. 2015 Sep-Oct;33(5):566-604. doi: 10.1016/j.biotechadv.2014.12.012. Epub 2015 Jan 7. Review.

PMID:
25575689
45.

Structural and biochemical characterization of the dual substrate recognition of the (R)-selective amine transaminase from Aspergillus fumigatus.

Skalden L, Thomsen M, Höhne M, Bornscheuer UT, Hinrichs W.

FEBS J. 2015 Jan;282(2):407-15. doi: 10.1111/febs.13149. Epub 2014 Dec 2.

46.

Intracranial electroencephalography power and phase synchronization changes during monaural and binaural beat stimulation.

Becher AK, Höhne M, Axmacher N, Chaieb L, Elger CE, Fell J.

Eur J Neurosci. 2015 Jan;41(2):254-63. doi: 10.1111/ejn.12760. Epub 2014 Oct 25.

PMID:
25345689
47.

Glycine oxidase based high-throughput solid-phase assay for substrate profiling and directed evolution of (R)- and (S)-selective amine transaminases.

Weiß MS, Pavlidis IV, Vickers C, Höhne M, Bornscheuer UT.

Anal Chem. 2014 Dec 2;86(23):11847-53. doi: 10.1021/ac503445y. Epub 2014 Nov 10.

PMID:
25321325
48.

Harmful effects of the azathioprine metabolite 6-mercaptopurine in vascular cells: induction of mineralization.

Prüfer J, Schuchardt M, Tölle M, Prüfer N, Höhne M, Zidek W, van der Giet M.

PLoS One. 2014 Jul 16;9(7):e101709. doi: 10.1371/journal.pone.0101709. eCollection 2014.

49.

A brief overview on IRM function across evolution.

Helmstädter M, Höhne M, Huber TB.

J Neurogenet. 2014 Sep-Dec;28(3-4):264-9. doi: 10.3109/01677063.2014.918976. Epub 2014 Jul 8. Review.

PMID:
24912528
50.

Relationship between starch degradation and carbon demand for maintenance and growth in Arabidopsis thaliana in different irradiance and temperature regimes.

Pilkington SM, Encke B, Krohn N, Höhne M, Stitt M, Pyl ET.

Plant Cell Environ. 2015 Jan;38(1):157-71. doi: 10.1111/pce.12381. Epub 2014 Jul 4.

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