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Proteostasis, oxidative stress and aging. Korovila I et al. Redox Biol. (2017)

Insulin-degrading enzyme: new therapeutic target for diabetes and Alzheimer's disease? Pivovarova O et al. Ann Med. (2016)

Advanced glycation end products and oxidative stress in type 2 diabetes mellitus. Nowotny K et al. Biomolecules. (2015)

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Items: 1 to 50 of 213


Texture analysis parameters derived from T1-and T2-weighted magnetic resonance images can reflect Ki67 index in soft tissue sarcoma.

Meyer HJ, Renatus K, Höhn AK, Hamerla G, Schopow N, Fakler J, Josten C, Surov A.

Surg Oncol. 2019 Sep;30:92-97. doi: 10.1016/j.suronc.2019.06.006. Epub 2019 Jun 22.


Preliminary Evidence for a Window of Increased Vulnerability to Sustain a Concussion in Females: A Brief Report.

La Fountaine MF, Hill-Lombardi V, Hohn AN, Leahy CL, Testa AJ.

Front Neurol. 2019 Jul 9;10:691. doi: 10.3389/fneur.2019.00691. eCollection 2019.


Endocervical adenocarcinoma in situ (AIS) with ovarian and pulmonary involvement: report of a case and review of the literature suggesting a "seed and soil hypothesis".

Horn LC, Höhn AK, Stark S, Einenkel J, Borte G, Haak A, Siebolts U, Brambs CE.

J Cancer Res Clin Oncol. 2019 Aug;145(8):2061-2069. doi: 10.1007/s00432-019-02966-4. Epub 2019 Jul 15. Review.


Combined parameter SUVmax/ADCmean predicts microvessel density in head and neck squamous cell carcinoma. Preliminary results.

Surov A, Meyer HJ, Höhn AK, Wienke A, Sabri O, Purz S.

Oral Oncol. 2019 Jul 3. pii: S1368-8375(19)30227-1. doi: 10.1016/j.oraloncology.2019.06.036. [Epub ahead of print] No abstract available.


Influence of patient and tumor characteristics on therapy persistence with letrozole in postmenopausal women with advanced breast cancer: results of the prospective observational EvAluate-TM study.

Wallwiener M, Nabieva N, Feisst M, Fehm T, de Waal J, Rezai M, Baier B, Baake G, Kolberg HC, Guggenberger M, Warm M, Harbeck N, Wuerstlein R, Deuker JU, Dall P, Richter B, Wachsmann G, Brucker C, Siebers JW, Popovic M, Kuhn T, Wolf C, Vollert HW, Breitbach GP, Janni W, Landthaler R, Kohls A, Rezek D, Noesselt T, Fischer G, Henschen S, Praetz T, Heyl V, Kühn T, Krauss T, Thomssen C, Hohn A, Tesch H, Mundhenke C, Hein A, Rauh C, Bayer CM, Schmidt K, Belleville E, Brucker SY, Hadji P, Beckmann MW, Wallwiener D, Kümmel S, Hartkopf A, Fasching PA.

BMC Cancer. 2019 Jun 21;19(1):611. doi: 10.1186/s12885-019-5806-y.


CT Texture Analysis-Correlations With Histopathology Parameters in Head and Neck Squamous Cell Carcinomas.

Meyer HJ, Hamerla G, Höhn AK, Surov A.

Front Oncol. 2019 May 28;9:444. doi: 10.3389/fonc.2019.00444. eCollection 2019.


Therapeutic drug monitoring-based dose optimisation of piperacillin/tazobactam to improve outcome in patients with sepsis (TARGET): a prospective, multi-centre, randomised controlled trial.

Hagel S, Fiedler S, Hohn A, Brinkmann A, Frey OR, Hoyer H, Schlattmann P, Kiehntopf M, Roberts JA, Pletz MW; TARGET Study Group.

Trials. 2019 Jun 6;20(1):330. doi: 10.1186/s13063-019-3437-x.


Whole-lesion ADC histogram analysis is not able to reflect microvessel density in HNSCC.

Meyer HJ, Hamerla G, Leifels L, Höhn AK, Surov A.

Medicine (Baltimore). 2019 May;98(21):e15520. doi: 10.1097/MD.0000000000015520.


18F-FDG-PET Can Predict Microvessel Density in Head and Neck Squamous Cell Carcinoma.

Surov A, Meyer HJ, Höhn AK, Wienke A, Sabri O, Purz S.

Cancers (Basel). 2019 Apr 15;11(4). pii: E543. doi: 10.3390/cancers11040543.


Endogenous advanced glycation end products in pancreatic islets after short-term carbohydrate intervention in obese, diabetes-prone mice.

Kehm R, Rückriemen J, Weber D, Deubel S, Grune T, Höhn A.

Nutr Diabetes. 2019 Mar 11;9(1):9. doi: 10.1038/s41387-019-0077-x.


The Prognostic Impact of Grading in FIGO IB and IIB Squamous Cell Cervical Carcinomas.

Brambs CE, Höhn AK, Hentschel B, Fischer U, Bilek K, Horn LC.

Geburtshilfe Frauenheilkd. 2019 Feb;79(2):198-204. doi: 10.1055/a-0828-7681. Epub 2019 Feb 18.


Associations between Histogram Analysis Parameters Derived from DCE-MRI and Histopathological Features including Expression of EGFR, p16, VEGF, Hif1-alpha, and p53 in HNSCC.

Meyer HJ, Leifels L, Hamerla G, Höhn AK, Surov A.

Contrast Media Mol Imaging. 2019 Jan 2;2019:5081909. doi: 10.1155/2019/5081909. eCollection 2019.


Role of Advanced Glycation End Products in Carcinogenesis and their Therapeutic Implications.

Schröter D, Höhn A.

Curr Pharm Des. 2018;24(44):5245-5251. doi: 10.2174/1381612825666190130145549.


Lipofuscin-dependent stimulation of microglial cells.

Leclaire MD, Nettels-Hackert G, König J, Höhn A, Grune T, Uhlig CE, Hansen U, Eter N, Heiduschka P.

Graefes Arch Clin Exp Ophthalmol. 2019 May;257(5):931-952. doi: 10.1007/s00417-019-04253-x. Epub 2019 Jan 28.


Histogram parameters derived from T2 weighted images are associated with histopathological findings in rectal cancer - a preliminary study.

Meyer HJ, Höhn AK, Hamerla G, Surov A.

Am J Transl Res. 2018 Nov 15;10(11):3790-3796. eCollection 2018.


Prognostic relevance of low-grade versus high-grade FIGO IB1 squamous cell uterine cervical carcinomas.

Horn LC, Höhn AK, Hentschel B, Fischer U, Bilek K, Brambs CE.

J Cancer Res Clin Oncol. 2019 Feb;145(2):457-462. doi: 10.1007/s00432-018-2793-3. Epub 2019 Jan 2.


Metabolo-volumetric parameters of 18F-FDG-PET can predict expression of EGFR and HIF 1alpha in uterine cervical cancer.

Surov A, Meyer HJ, Höhn AK, Schob S, Winter K, Sabri O, Purz S.

Cancer Biomark. 2019;24(1):135-140. doi: 10.3233/CBM-182019.


Intravascular Cooling Device Versus Esophageal Heat Exchanger for Mild Therapeutic Hypothermia in an Experimental Setting.

Schroeder DC, Maul AC, Guschlbauer M, Finke SR, de la Puente Bethencourt D, Becker I, Padosch SA, Hohn A, Annecke T, Böttiger BW, Sterner-Kock A, Herff H.

Anesth Analg. 2018 Nov 9. doi: 10.1213/ANE.0000000000003922. [Epub ahead of print]


Attenuation of Spontaneous Baroreceptor Sensitivity after Concussion.

LA Fountaine MF, Hohn AN, Testa AJ, Weir JP.

Med Sci Sports Exerc. 2019 Apr;51(4):792-797. doi: 10.1249/MSS.0000000000001833.


Associations between whole tumor histogram analysis parameters derived from ADC maps and expression of EGFR, VEGF, Hif 1-alpha, Her-2 and Histone 3 in uterine cervical cancer.

Meyer HJ, Gundermann P, Höhn AK, Hamerla G, Surov A.

Magn Reson Imaging. 2019 Apr;57:68-74. doi: 10.1016/j.mri.2018.10.016. Epub 2018 Oct 25.


Whole Lesion Histogram Analysis Derived From Morphological MRI Sequences Might be Able to Predict EGFR- and Her2-Expression in Cervical Cancer.

Meyer HJ, Hamerla G, Höhn AK, Surov A.

Acad Radiol. 2019 Aug;26(8):e208-e215. doi: 10.1016/j.acra.2018.09.008. Epub 2018 Oct 11.


Combined Metabolo-Volumetric Parameters of 18F-FDG-PET and MRI Can Predict Tumor Cellularity, Ki67 Level and Expression of HIF 1alpha in Head and Neck Squamous Cell Carcinoma: A Pilot Study.

Surov A, Meyer HJ, Höhn AK, Sabri O, Purz S.

Transl Oncol. 2019 Jan;12(1):8-14. doi: 10.1016/j.tranon.2018.08.018. Epub 2018 Sep 18.


ADC-histogram analysis in head and neck squamous cell carcinoma. Associations with different histopathological features including expression of EGFR, VEGF, HIF-1α, Her 2 and p53. A preliminary study.

Meyer HJ, Leifels L, Hamerla G, Höhn AK, Surov A.

Magn Reson Imaging. 2018 Dec;54:214-217. doi: 10.1016/j.mri.2018.07.013. Epub 2018 Sep 4.


Knocking the Chest as a "Bridge to Pacemaker": Treatment of Bradyasystole by Percussion Pacing.

Drinhaus H, Hohn A, Annecke T.

Circ J. 2018 Aug 24;82(9):2445-2446. doi: 10.1253/circj.CJ-17-0783. Epub 2018 Aug 1. No abstract available.


Incidence of peri-operative paediatric cardiac arrest and the influence of a specialised paediatric anaesthesia team: Retrospective cohort study.

Hohn A, Trieschmann U, Franklin J, Machatschek JN, Kaufmann J, Herff H, Hinkelbein J, Annecke T, Böttiger BW, Padosch SA.

Eur J Anaesthesiol. 2019 Jan;36(1):55-63. doi: 10.1097/EJA.0000000000000863.


Bioinformatical Analysis of Organ-Related (Heart, Brain, Liver, and Kidney) and Serum Proteomic Data to Identify Protein Regulation Patterns and Potential Sepsis Biomarkers.

Hohn A, Iovino I, Cirillo F, Drinhaus H, Kleinbrahm K, Boehm L, De Robertis E, Hinkelbein J.

Biomed Res Int. 2018 Mar 21;2018:3576157. doi: 10.1155/2018/3576157. eCollection 2018.


Time Dependent Pathway Activation of Signalling Cascades in Rat Organs after Short-Term Hyperoxia.

Hinkelbein J, Braunecker S, Danz M, Böhm L, Hohn A.

Int J Mol Sci. 2018 Jul 4;19(7). pii: E1960. doi: 10.3390/ijms19071960.


Associations Between [18F]FDG-PET and Complex Histopathological Parameters Including Tumor Cell Count and Expression of KI 67, EGFR, VEGF, HIF-1α, and p53 in Head and Neck Squamous Cell Carcinoma.

Surov A, Meyer HJ, Höhn AK, Winter K, Sabri O, Purz S.

Mol Imaging Biol. 2019 Apr;21(2):368-374. doi: 10.1007/s11307-018-1223-x.


Is Who you Ask Important? Concordance Between Survey and Registry Data on Medication Use Among Self- and Proxy-Respondents in the Longitudinal Study of Aging Danish Twins and the Danish 1905-Cohort Study.

Oksuzyan A, Sauer T, Gampe J, Höhn A, Wod M, Christensen K, Wastesson JW.

J Gerontol A Biol Sci Med Sci. 2019 Apr 23;74(5):742-747. doi: 10.1093/gerona/gly104.


Prolonged antibiotic prophylaxis after thoracoabdominal esophagectomy does not reduce the risk of pneumonia in the first 30 days: a retrospective before-and-after analysis.

Hochreiter M, Uhling M, Sisic L, Bruckner T, Heininger A, Hohn A, Ott K, Schmidt T, Berger MM, Richter DC, Büchler M, Weigand MA, Busch CJ.

Infection. 2018 Oct;46(5):617-624. doi: 10.1007/s15010-018-1160-2. Epub 2018 Jun 5.


Adherence to a procalcitonin-guided antibiotic treatment protocol in patients with severe sepsis and septic shock.

Hohn A, Balfer N, Heising B, Hertel S, Wiemer JC, Hochreiter M, Schröder S.

Ann Intensive Care. 2018 Jun 4;8(1):68. doi: 10.1186/s13613-018-0415-5.


Did human activity really trigger the late Holocene rainforest crisis in Central Africa?

Clist B, Bostoen K, de Maret P, Eggert MKH, Höhn A, Mbida Mindzié C, Neumann K, Seidensticker D.

Proc Natl Acad Sci U S A. 2018 May 22;115(21):E4733-E4734. doi: 10.1073/pnas.1805247115. Epub 2018 May 8. No abstract available.


In-flight cardiac arrest and in-flight cardiopulmonary resuscitation during commercial air travel: consensus statement and supplementary treatment guideline from the German Society of Aerospace Medicine (DGLRM).

Hinkelbein J, Böhm L, Braunecker S, Genzwürker HV, Kalina S, Cirillo F, Komorowski M, Hohn A, Siedenburg J, Bernhard M, Janicke I, Adler C, Jansen S, Glaser E, Krawczyk P, Miesen M, Andres J, De Robertis E, Neuhaus C.

Intern Emerg Med. 2018 Dec;13(8):1305-1322. doi: 10.1007/s11739-018-1856-4. Epub 2018 May 5.


Influence of side-effects on early therapy persistence with letrozole in post-menopausal patients with early breast cancer: Results of the prospective EvAluate-TM study.

Nabieva N, Fehm T, Häberle L, de Waal J, Rezai M, Baier B, Baake G, Kolberg HC, Guggenberger M, Warm M, Harbeck N, Wuerstlein R, Deuker JU, Dall P, Richter B, Wachsmann G, Brucker C, Siebers JW, Popovic M, Kuhn T, Wolf C, Vollert HW, Breitbach GP, Janni W, Landthaler R, Kohls A, Rezek D, Noesselt T, Fischer G, Henschen S, Praetz T, Heyl V, Kühn T, Krauss T, Thomssen C, Hohn A, Tesch H, Mundhenke C, Hein A, Hack CC, Schmidt K, Belleville E, Brucker SY, Kümmel S, Beckmann MW, Wallwiener D, Hadji P, Fasching PA.

Eur J Cancer. 2018 Jun;96:82-90. doi: 10.1016/j.ejca.2018.03.020. Epub 2018 Apr 18.


Protein aggregates and proteostasis in aging: Amylin and β-cell function.

Press M, Jung T, König J, Grune T, Höhn A.

Mech Ageing Dev. 2019 Jan;177:46-54. doi: 10.1016/j.mad.2018.03.010. Epub 2018 Mar 23. Review.


[18F]fallypride-PET/CT Analysis of the Dopamine D₂/D₃ Receptor in the Hemiparkinsonian Rat Brain Following Intrastriatal Botulinum Neurotoxin A Injection.

Mann T, Kurth J, Hawlitschka A, Stenzel J, Lindner T, Polei S, Hohn A, Krause BJ, Wree A.

Molecules. 2018 Mar 6;23(3). pii: E587. doi: 10.3390/molecules23030587.


Gender differences in the use of anti-infective medications before and after widowhood: a register-based study.

Santacroce A, Wastesson JW, Höhn A, Christensen K, Oksuzyan A.

J Epidemiol Community Health. 2018 Jun;72(6):526-531. doi: 10.1136/jech-2017-210114. Epub 2018 Feb 19.


Antifibrogenic effects of vitamin D derivatives on mouse pancreatic stellate cells.

Wallbaum P, Rohde S, Ehlers L, Lange F, Hohn A, Bergner C, Schwarzenböck SM, Krause BJ, Jaster R.

World J Gastroenterol. 2018 Jan 14;24(2):170-178. doi: 10.3748/wjg.v24.i2.170.


[Cancer patients in operative intensive care medicine].

Annecke T, Hohn A, Böll B, Kochanek M.

Anaesthesist. 2018 Feb;67(2):83-92. doi: 10.1007/s00101-018-0406-9. Review. German.


Age-related oxidative changes in pancreatic islets are predominantly located in the vascular system.

Kehm R, König J, Nowotny K, Jung T, Deubel S, Gohlke S, Schulz TJ, Höhn A.

Redox Biol. 2018 May;15:387-393. doi: 10.1016/j.redox.2017.12.015. Epub 2017 Dec 29.


"Cyt/Nuc," a Customizable and Documenting ImageJ Macro for Evaluation of Protein Distributions Between Cytosol and Nucleus.

Grune T, Kehm R, Höhn A, Jung T.

Biotechnol J. 2018 May;13(5):e1700652. doi: 10.1002/biot.201700652. Epub 2018 Feb 9.


Self-confidence and level of knowledge after cardiopulmonary resuscitation training in 14 to 18-year-old schoolchildren: A randomised-interventional controlled study in secondary schools in Germany.

Wingen S, Schroeder DC, Ecker H, Steinhauser S, Altin S, Stock S, Lechleuthner A, Hohn A, Böttiger BW.

Eur J Anaesthesiol. 2018 Jul;35(7):519-526. doi: 10.1097/EJA.0000000000000766.


Impact of the Weekday of Surgery on Outcome in Gastric Cancer Patients who Underwent D2-Gastrectomy.

Berlth F, Messerle K, Plum PS, Chon SH, von Ambüren J, Hohn A, Dübbers M, Bruns CJ, Mönig SP, Bollschweiler E, Hölscher AH, Alakus H.

World J Surg. 2018 Jun;42(6):1811-1818. doi: 10.1007/s00268-017-4398-4.


[68Ga]pentixafor for CXCR4 imaging in a PC-3 prostate cancer xenograft model - comparison with [18F]FDG PET/CT, MRI and ex vivo receptor expression.

Schwarzenböck SM, Stenzel J, Otto T, Helldorff HV, Bergner C, Kurth J, Polei S, Lindner T, Rauer R, Hohn A, Hakenberg OW, Wester HJ, Vollmar B, Krause BJ.

Oncotarget. 2017 Sep 16;8(56):95606-95619. doi: 10.18632/oncotarget.21024. eCollection 2017 Nov 10.


Awake tracheotomy in a patient with stridor and dyspnoea caused by a sizeable malignant thyroid tumor: a case report and short review of the literature.

Hohn A, Kauliņš T, Hinkelbein J, Kauliņa K, Kopp A, Russo SG, Kohlen S, Schröder S.

Clin Case Rep. 2017 Oct 5;5(11):1891-1895. doi: 10.1002/ccr3.1216. eCollection 2017 Nov.


Application of in vivo imaging techniques to monitor therapeutic efficiency of PLX4720 in an experimental model of microsatellite instable colorectal cancer.

Rohde S, Lindner T, Polei S, Stenzel J, Borufka L, Achilles S, Hartmann E, Lange F, Maletzki C, Linnebacher M, Glass Ä, Schwarzenböck SM, Kurth J, Hohn A, Vollmar B, Krause BJ, Jaster R.

Oncotarget. 2017 Jul 15;8(41):69756-69767. doi: 10.18632/oncotarget.19263. eCollection 2017 Sep 19.

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