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Best matches for Höcker B[au]:

Highlight issue: protein design. Sterner R et al. Biol Chem. (2017)

Strategies for designing non-natural enzymes and binders. Lechner H et al. Curr Opin Chem Biol. (2018)

Editorial overview: A perspective on protein evolution. Höcker B et al. Curr Opin Struct Biol. (2018)

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Items: 1 to 50 of 85

1.

Reconstructing the Remote Origins of a Fold Singleton from a Flavodoxin-Like Ancestor.

Toledo-Patiño S, Chaubey M, Coles M, Höcker B.

Biochemistry. 2019 Dec 3;58(48):4790-4793. doi: 10.1021/acs.biochem.9b00900. Epub 2019 Nov 20.

2.

Infections among pediatric transplant candidates: An approach to decision-making.

L'Huillier AG, Green M, Danziger-Isakov L, Chaudhuri A, Höcker B, Van der Linden D, Goddard L, Ardura MI, Stephens D, Verma A, Evans HM, McCulloch M, Michaels MG, Posfay-Barbe KM, Allen UD.

Pediatr Transplant. 2019 May;23(3):e13375. doi: 10.1111/petr.13375. Epub 2019 Mar 5.

PMID:
30838753
3.

Initial treatment of steroid-sensitive idiopathic nephrotic syndrome in children with mycophenolate mofetil versus prednisone: protocol for a randomised, controlled, multicentre trial (INTENT study).

Ehren R, Benz MR, Doetsch J, Fichtner A, Gellermann J, Haffner D, Höcker B, Hoyer PF, Kästner B, Kemper MJ, Konrad M, Luntz S, Querfeld U, Sander A, Toenshoff B, Weber LT; Gesellschaft für Pädiatrische Nephrologie (GPN).

BMJ Open. 2018 Oct 10;8(10):e024882. doi: 10.1136/bmjopen-2018-024882.

4.

Strategies for designing non-natural enzymes and binders.

Lechner H, Ferruz N, Höcker B.

Curr Opin Chem Biol. 2018 Dec;47:67-76. doi: 10.1016/j.cbpa.2018.07.022. Epub 2018 Sep 22. Review.

5.

Pediatric transplantation case conference: Update on cytomegalovirus.

Pellett Madan R, Allen UD, Green M, Höcker B, Michaels MG, Varela-Fascinetto G, Danziger-Isakov L; Pediatric Subgroup for the International Consensus Guidelines on the Management of Cytomegalovirus in Solid Organ Transplantation and the International Pediatric Transplant Association Infectious Disease Committee.

Pediatr Transplant. 2018 Nov;22(7):e13276. doi: 10.1111/petr.13276. Epub 2018 Sep 10.

PMID:
30203626
6.

Steroid withdrawal improves blood pressure control and nocturnal dipping in pediatric renal transplant recipients: analysis of a prospective, randomized, controlled trial.

Höcker B, Weber LT, John U, Drube J, Fehrenbach H, Klaus G, Pohl M, Seeman T, Fichtner A, Wühl E, Tönshoff B.

Pediatr Nephrol. 2019 Feb;34(2):341-348. doi: 10.1007/s00467-018-4069-1. Epub 2018 Sep 4.

PMID:
30178240
7.

Engineering an AB5 Protein Carrier.

Lichtenstein BR, Höcker B.

Sci Rep. 2018 Aug 23;8(1):12643. doi: 10.1038/s41598-018-30910-y.

8.

Epidemiology of and Risk Factors for BK Polyomavirus Replication and Nephropathy in Pediatric Renal Transplant Recipients: An International CERTAIN Registry Study.

Höcker B, Schneble L, Murer L, Carraro A, Pape L, Kranz B, Oh J, Zirngibl M, Dello Strologo L, Büscher A, Weber LT, Awan A, Pohl M, Bald M, Printza N, Rusai K, Peruzzi L, Topaloglu R, Fichtner A, Krupka K, Köster L, Bruckner T, Schnitzler P, Hirsch HH, Tönshoff B.

Transplantation. 2019 Jun;103(6):1224-1233. doi: 10.1097/TP.0000000000002414.

PMID:
30130322
9.

JC polyomavirus replication and associated disease in pediatric renal transplantation: an international CERTAIN Registry study.

Höcker B, Tabatabai J, Schneble L, Oh J, Thiel F, Pape L, Rusai K, Topaloglu R, Kranz B, Klaus G, Printza N, Yavascan O, Fichtner A, Krupka K, Bruckner T, Waldherr R, Pawlita M, Schnitzler P, Hirsch HH, Tönshoff B.

Pediatr Nephrol. 2018 Dec;33(12):2343-2352. doi: 10.1007/s00467-018-4029-9. Epub 2018 Jul 30.

PMID:
30058047
10.

Redesign of LAOBP to bind novel l-amino acid ligands.

Banda-Vázquez J, Shanmugaratnam S, Rodríguez-Sotres R, Torres-Larios A, Höcker B, Sosa-Peinado A.

Protein Sci. 2018 May;27(5):957-968. doi: 10.1002/pro.3403. Epub 2018 Mar 22.

11.

Prevalence, morbidity, and therapy of hepatitis E virus infection in pediatric renal allograft recipients.

Cordts SE, Schneble L, Schnitzler P, Wenzel JJ, Vinke T, Rieger S, Fichtner A, Tönshoff B, Höcker B.

Pediatr Nephrol. 2018 Jul;33(7):1215-1225. doi: 10.1007/s00467-018-3905-7. Epub 2018 Mar 2.

PMID:
29500631
12.

Editorial overview: A perspective on protein evolution.

Höcker B, Winther JR.

Curr Opin Struct Biol. 2018 Feb;48:viii-ix. doi: 10.1016/j.sbi.2018.01.013. No abstract available.

PMID:
29475491
13.

Association of angiotensin II type 1 receptor antibodies with graft histology, function and survival in paediatric renal transplant recipients.

Fichtner A, Süsal C, Schröder C, Höcker B, Rieger S, Waldherr R, Westhoff JH, Sander A, Dragun D, Tönshoff B.

Nephrol Dial Transplant. 2018 Jun 1;33(6):1065-1072. doi: 10.1093/ndt/gfy008.

PMID:
29444269
14.

Vaccination titres pre- and post-transplant in paediatric renal transplant recipients and the impact of immunosuppressive therapy.

Höcker B, Aguilar M, Schnitzler P, Pape L, Bald M, König J, Marks SD, Genc G, Büscher A, Kemper MJ, Billing H, Pohl M, Dello Strologo L, Webb NJA, Rieger S, Mankertz A, Krupka K, Bruckner T, Fichtner A, Tönshoff B.

Pediatr Nephrol. 2018 May;33(5):897-910. doi: 10.1007/s00467-017-3868-0. Epub 2018 Jan 10.

PMID:
29322328
15.

Incomplete vaccination coverage in European children with end-stage kidney disease prior to renal transplantation.

Höcker B, Aguilar M, Schnitzler P, Pape L, Dello Strologo L, Webb NJA, Bald M, Genc G, Billing H, König J, Büscher A, Kemper MJ, Marks SD, Pohl M, Wigger M, Topaloglu R, Rieger S, Krupka K, Bruckner T, Fichtner A, Tönshoff B.

Pediatr Nephrol. 2018 Feb;33(2):341-350. doi: 10.1007/s00467-017-3776-3. Epub 2017 Oct 5.

PMID:
28983694
16.

Performance evaluation of mobile downflow booths for reducing airborne particles in the workplace.

Lo LM, Hocker B, Steltz AE, Kremer J, Feng HA.

J Occup Environ Hyg. 2017 Nov;14(11):839-852. doi: 10.1080/15459624.2017.1335404.

PMID:
28644723
17.

Dyslipidemia after pediatric renal transplantation-The impact of immunosuppressive regimens.

Habbig S, Volland R, Krupka K, Querfeld U, Dello Strologo L, Noyan A, Yalcinkaya F, Topaloglu R, Webb NJ, Kemper MJ, Pape L, Bald M, Kranz B, Taylan C, Höcker B, Tönshoff B, Weber LT.

Pediatr Transplant. 2017 May;21(3). doi: 10.1111/petr.12914. Epub 2017 Mar 28.

PMID:
28370750
18.

Single-Nucleotide Polymorphism of CYP3A5 Impacts the Exposure to Tacrolimus in Pediatric Renal Transplant Recipients: A Pharmacogenetic Substudy of the TWIST Trial.

Billing H, Höcker B, Fichtner A, van Damme-Lombaerts R, Friman S, Jaray J, Vondrak K, Sarvary E, Dello Strologo L, Oellerich M, von Ahsen N, Tönshoff B.

Ther Drug Monit. 2017 Feb;39(1):21-28. doi: 10.1097/FTD.0000000000000361.

PMID:
28030534
19.

Highlight issue: protein design.

Sterner R, Höcker B, Kolmar H.

Biol Chem. 2017 Jan 1;398(1):1-2. doi: 10.1515/hsz-2016-0322. No abstract available.

PMID:
27837592
20.

Prospective study on the potential of RAAS blockade to halt renal disease in Alport syndrome patients with heterozygous mutations.

Stock J, Kuenanz J, Glonke N, Sonntag J, Frese J, Tönshoff B, Höcker B, Hoppe B, Feldkötter M, Pape L, Lerch C, Wygoda S, Weber M, Müller GA, Gross O.

Pediatr Nephrol. 2017 Jan;32(1):131-137. Epub 2016 Jul 11.

PMID:
27402170
21.

PocketOptimizer and the Design of Ligand Binding Sites.

Stiel AC, Nellen M, Höcker B.

Methods Mol Biol. 2016;1414:63-75. doi: 10.1007/978-1-4939-3569-7_5.

PMID:
27094286
22.

Association of C1q-fixing DSA with late graft failure in pediatric renal transplant recipients.

Fichtner A, Süsal C, Höcker B, Rieger S, Waldherr R, Westhoff JH, Sander A, Opelz G, Tönshoff B.

Pediatr Nephrol. 2016 Jul;31(7):1157-66. doi: 10.1007/s00467-016-3322-8. Epub 2016 Feb 29.

PMID:
26928311
23.

Cytomegalovirus Infection in Pediatric Renal Transplantation and the Impact of Chemoprophylaxis With (Val-)Ganciclovir.

Höcker B, Zencke S, Krupka K, Fichtner A, Pape L, Dello Strologo L, Guzzo I, Topaloglu R, Kranz B, König J, Bald M, Webb NJ, Noyan A, Dursun H, Marks S, Yalcinkaya F, Thiel F, Billing H, Pohl M, Fehrenbach H, Bruckner T, Tönshoff B.

Transplantation. 2016 Apr;100(4):862-70. doi: 10.1097/TP.0000000000000888.

PMID:
26736017
24.

Impact of Everolimus and Low-Dose Cyclosporin on Cytomegalovirus Replication and Disease in Pediatric Renal Transplantation.

Höcker B, Zencke S, Pape L, Krupka K, Köster L, Fichtner A, Dello Strologo L, Guzzo I, Topaloglu R, Kranz B, König J, Bald M, Webb NJ, Noyan A, Dursun H, Marks S, Ozcakar ZB, Thiel F, Billing H, Pohl M, Fehrenbach H, Schnitzler P, Bruckner T, Ahlenstiel-Grunow T, Tönshoff B.

Am J Transplant. 2016 Mar;16(3):921-9. doi: 10.1111/ajt.13649. Epub 2016 Feb 3.

25.

De novo design of a four-fold symmetric TIM-barrel protein with atomic-level accuracy.

Huang PS, Feldmeier K, Parmeggiani F, Velasco DAF, Höcker B, Baker D.

Nat Chem Biol. 2016 Jan;12(1):29-34. doi: 10.1038/nchembio.1966. Epub 2015 Nov 23.

26.

Efficacy and Safety of an Everolimus- vs. a Mycophenolate Mofetil-Based Regimen in Pediatric Renal Transplant Recipients.

Brunkhorst LC, Fichtner A, Höcker B, Burmeister G, Ahlenstiel-Grunow T, Krupka K, Bald M, Zapf A, Tönshoff B, Pape L.

PLoS One. 2015 Sep 25;10(9):e0135439. doi: 10.1371/journal.pone.0135439. eCollection 2015.

27.

Integrating data from multiple sources for data completeness in a web-based registry for pediatric renal transplantation--the CERTAIN Registry.

Köster L, Krupka K, Höcker B, Rahmel A, Samuel U, Zanen W, Opelz G, Süsal C, Döhler B, Plotnicki L, Kohl CD, Knaup P, Tönshoff B.

Stud Health Technol Inform. 2015;216:1049.

PMID:
26262348
28.

[Cytomegalovirus after renal transplantation - diagnosis, prevention and treatment].

Kliem V, Sester M, Nitschke M, Tönshoff B, Budde K, Hauser IA, Schmitt M, Höcker B, Witzke O.

Dtsch Med Wochenschr. 2015 Apr;140(8):612-5. doi: 10.1055/s-0041-100777. Epub 2015 Apr 16. German. No abstract available.

PMID:
25945912
29.

Clinical and molecular characterization of patients with heterozygous mutations in wilms tumor suppressor gene 1.

Lehnhardt A, Karnatz C, Ahlenstiel-Grunow T, Benz K, Benz MR, Budde K, Büscher AK, Fehr T, Feldkötter M, Graf N, Höcker B, Jungraithmayr T, Klaus G, Koehler B, Konrad M, Kranz B, Montoya CR, Müller D, Neuhaus TJ, Oh J, Pape L, Pohl M, Royer-Pokora B, Querfeld U, Schneppenheim R, Staude H, Spartà G, Timmermann K, Wilkening F, Wygoda S, Bergmann C, Kemper MJ.

Clin J Am Soc Nephrol. 2015 May 7;10(5):825-31. doi: 10.2215/CJN.10141014. Epub 2015 Mar 27.

30.

Identification of protein scaffolds for enzyme design using scaffold selection.

Stiel AC, Feldmeier K, Höcker B.

Methods Mol Biol. 2014;1216:183-96. doi: 10.1007/978-1-4939-1486-9_9. Review.

PMID:
25213416
31.

Evolutionary relationship of two ancient protein superfolds.

Farías-Rico JA, Schmidt S, Höcker B.

Nat Chem Biol. 2014 Sep;10(9):710-5. doi: 10.1038/nchembio.1579. Epub 2014 Jul 13.

PMID:
25038785
32.

Design of proteins from smaller fragments-learning from evolution.

Höcker B.

Curr Opin Struct Biol. 2014 Aug;27:56-62. doi: 10.1016/j.sbi.2014.04.007. Epub 2014 May 25. Review.

PMID:
24865156
33.

Designing protein function - macromolecular design.

Höcker B, Midelfort K.

J Struct Biol. 2014 Feb;185(2):135. doi: 10.1016/j.jsb.2014.01.011. No abstract available.

PMID:
24491279
34.

Computational protein design of ligand binding and catalysis.

Feldmeier K, Höcker B.

Curr Opin Chem Biol. 2013 Dec;17(6):929-33. Review.

PMID:
24466576
35.

Engineering chimaeric proteins from fold fragments: 'hopeful monsters' in protein design.

Höcker B.

Biochem Soc Trans. 2013 Oct;41(5):1137-40. doi: 10.1042/BST20130099. Review.

PMID:
24059498
36.

Growing experience with mTOR inhibitors in pediatric solid organ transplantation.

Ganschow R, Pape L, Sturm E, Bauer J, Melter M, Gerner P, Höcker B, Ahlenstiel T, Kemper M, Brinkert F, Sachse MM, Tönshoff B.

Pediatr Transplant. 2013 Nov;17(7):694-706. doi: 10.1111/petr.12147. Epub 2013 Sep 4. Review.

PMID:
24004351
37.

Longitudinal growth on an everolimus- versus an MMF-based steroid-free immunosuppressive regimen in paediatric renal transplant recipients.

Billing H, Burmeister G, Plotnicki L, Ahlenstiel T, Fichtner A, Sander A, Höcker B, Tönshoff B, Pape L.

Transpl Int. 2013 Sep;26(9):903-9. doi: 10.1111/tri.12148. Epub 2013 Jul 19.

38.

Molecular engineering of organophosphate hydrolysis activity from a weak promiscuous lactonase template.

Meier MM, Rajendran C, Malisi C, Fox NG, Xu C, Schlee S, Barondeau DP, Höcker B, Sterner R, Raushel FM.

J Am Chem Soc. 2013 Aug 7;135(31):11670-7. doi: 10.1021/ja405911h. Epub 2013 Jul 29.

39.

Change in protein-ligand specificity through binding pocket grafting.

Scheib U, Shanmugaratnam S, Farías-Rico JA, Höcker B.

J Struct Biol. 2014 Feb;185(2):186-92. doi: 10.1016/j.jsb.2013.06.002. Epub 2013 Jun 17.

PMID:
23792166
40.

The CERTAIN Registry: a novel, web-based registry and research platform for pediatric renal transplantation in Europe.

Plotnicki L, Kohl CD, Höcker B, Krupka K, Rahmel A, Pape L, Hoyer P, Marks SD, Webb NJ, Söylemezoglu O, Topaloglu R, Szabo AJ, Seeman T, Marlies Cornelissen EA, Knops N, Grenda R, Tönshoff B.

Transplant Proc. 2013 May;45(4):1414-7. doi: 10.1016/j.transproceed.2013.01.007.

PMID:
23726585
41.

Design of chimeric proteins by combination of subdomain-sized fragments.

Rico JA, Höcker B.

Methods Enzymol. 2013;523:389-405. doi: 10.1016/B978-0-12-394292-0.00018-7.

PMID:
23422440
42.

Binding pocket optimization by computational protein design.

Malisi C, Schumann M, Toussaint NC, Kageyama J, Kohlbacher O, Höcker B.

PLoS One. 2012;7(12):e52505. doi: 10.1371/journal.pone.0052505. Epub 2012 Dec 27.

43.

Soluble CD30 and ELISA-detected human leukocyte antigen antibodies for the prediction of acute rejection in pediatric renal transplant recipients.

Billing H, Sander A, Süsal C, Ovens J, Feneberg R, Höcker B, Vondrak K, Grenda R, Friman S, Milford DV, Lucan M, Opelz G, Tönshoff B.

Transpl Int. 2013 Mar;26(3):331-8. doi: 10.1111/tri.12049. Epub 2012 Dec 31.

44.

EBV-specific T-cell immunity in pediatric solid organ graft recipients with posttransplantation lymphoproliferative disease.

Wilsdorf N, Eiz-Vesper B, Henke-Gendo C, Diestelhorst J, Oschlies I, Hussein K, Pape L, Baumann U, Tönshoff B, Pohl M, Höcker B, Wingen AM, Klapper W, Kreipe H, Schulz TF, Klein C, Maecker-Kolhoff B.

Transplantation. 2013 Jan 15;95(1):247-55. doi: 10.1097/TP.0b013e318279968d.

PMID:
23222899
45.

Structural biology: A toolbox for protein design.

Höcker B.

Nature. 2012 Nov 8;491(7423):204-5. doi: 10.1038/491204a. No abstract available.

PMID:
23135466
46.

A highly stable protein chimera built from fragments of different folds.

Shanmugaratnam S, Eisenbeis S, Höcker B.

Protein Eng Des Sel. 2012 Nov;25(11):699-703. doi: 10.1093/protein/gzs074. Epub 2012 Oct 18.

PMID:
23081840
47.

Epidemiology and morbidity of Epstein-Barr virus infection in pediatric renal transplant recipients: a multicenter, prospective study.

Höcker B, Fickenscher H, Delecluse HJ, Böhm S, Küsters U, Schnitzler P, Pohl M, John U, Kemper MJ, Fehrenbach H, Wigger M, Holder M, Schröder M, Billing H, Fichtner A, Feneberg R, Sander A, Köpf-Shakib S, Süsal C, Tönshoff B.

Clin Infect Dis. 2013 Jan;56(1):84-92. doi: 10.1093/cid/cis823. Epub 2012 Oct 5.

PMID:
23042966
48.

(Val-)Ganciclovir prophylaxis reduces Epstein-Barr virus primary infection in pediatric renal transplantation.

Höcker B, Böhm S, Fickenscher H, Küsters U, Schnitzler P, Pohl M, John U, Kemper MJ, Fehrenbach H, Wigger M, Holder M, Schröder M, Feneberg R, Köpf-Shakib S, Tönshoff B.

Transpl Int. 2012 Jul;25(7):723-31. doi: 10.1111/j.1432-2277.2012.01485.x. Epub 2012 Apr 25.

49.

Protein design: A metalloenzyme reloaded.

Höcker B.

Nat Chem Biol. 2012 Feb 15;8(3):224-5. doi: 10.1038/nchembio.800. No abstract available.

PMID:
22337091
50.

Potential of fragment recombination for rational design of proteins.

Eisenbeis S, Proffitt W, Coles M, Truffault V, Shanmugaratnam S, Meiler J, Höcker B.

J Am Chem Soc. 2012 Mar 7;134(9):4019-22. doi: 10.1021/ja211657k. Epub 2012 Feb 23.

PMID:
22329686

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