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Items: 1 to 50 of 331

1.

Rare encounters: Primary pineal malignant melanoma with lepto-meningeal spread. Case report and literature review on management challenges and outcomes.

Hajhouji F, Ganau M, Helene C, Romano A, Gubian A, Proust F, Chibbaro S.

J Clin Neurosci. 2019 Jul;65:161-165. doi: 10.1016/j.jocn.2019.03.029. Epub 2019 May 6. No abstract available.

PMID:
31072741
2.

"The Subdural Collection" a Great Simulator: Case Report and Literature Review.

Houssem A, Helene C, Francois P, Salvatore C.

Asian J Neurosurg. 2018 Jul-Sep;13(3):851-853. doi: 10.4103/ajns.AJNS_325_16.

3.

Prognostic value of isolated tumor cells and micrometastases of lymph nodes in early-stage breast cancer: a French sentinel node multicenter cohort study.

Houvenaeghel G, Classe JM, Garbay JR, Giard S, Cohen M, Faure C, Hélène C, Belichard C, Uzan S, Hudry D, Azuar P, Villet R, Penault Llorca F, Tunon de Lara C, Goncalves A, Esterni B; et al.

Breast. 2014 Oct;23(5):561-6. doi: 10.1016/j.breast.2014.04.004. Epub 2014 May 27.

PMID:
24874284
4.

Role of size and composition of traffic and agricultural aerosols in the molecular responses triggered in airway epithelial cells.

Val S, Martinon L, Cachier H, Yahyaoui A, Marfaing H, Baeza-Squiban A.

Inhal Toxicol. 2011 Sep;23(11):627-40. doi: 10.3109/08958378.2011.599445. Erratum in: Inhal Toxicol. 2011 Dec;23(14):957. Stéphanie, Val [corrected to Val, Stéphanie]; Laurent, Martinon [corrected to Martinon, Laurent]; Hélène, Cachier [corrected to Cachier, Hélène]; Abderrazak, Yahyaoui [corrected to Yahyaoui, Abderrazak]; Hélène, Marfaing [corrected to Marfaing, Hé.

PMID:
21879948
5.

[Stabilization of G x C-containing DNA duplexes by polyamides with parallel orientation in the minor groove].

Siniakov AN, Butorin AS, Héléne C, Riabinin VA.

Bioorg Khim. 2004 Sep-Oct;30(5):558-60. Russian.

PMID:
15562979
6.

Oligonucleotide--minor groove binder 1:2 conjugates: side by side parallel minor groove binder motif in stabilization of DNA duplex.

Ryabinin VA, Boutorine AS, Hélène C, Denisov AY, Pyshnyi DV, Sinyakov AN.

Nucleosides Nucleotides Nucleic Acids. 2004 Oct;23(6-7):953-68.

PMID:
15560087
7.

Oligonucleotide-minor groove binder conjugates and their complexes with complementary DNA: effect of conjugate structural factors on the thermal stability of duplexes.

Ryabinin VA, Boutorine AS, Hélène C, Pyshnyi DV, Sinyakov AN.

Nucleosides Nucleotides Nucleic Acids. 2004 May;23(5):789-803.

PMID:
15281367
8.

Stabilization of DNA double and triple helices by conjugation of minor groove binders to oligonucleotides.

Boutorine AS, Ryabinin VA, Novopashina DS, Venyaminova AG, Hélène C, Sinyakov AS.

Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):1267-72.

PMID:
14565396
9.

Oligonucleotides and derivatives as gene-specific control agents.

Sun JS, Hélène C.

Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):489-505. Review.

PMID:
14565225
10.

Spatial organization of topoisomerase I-mediated DNA cleavage induced by camptothecin-oligonucleotide conjugates.

Arimondo PB, Angenault S, Halby L, Boutorine A, Schmidt F, Monneret C, Garestier T, Sun JS, Bailly C, Hélène C.

Nucleic Acids Res. 2003 Jul 15;31(14):4031-40.

11.

Design of new anti-cancer agents based on topoisomerase poisons targeted to specific DNA sequences.

Arimondo PB, Hélène C.

Curr Med Chem Anticancer Agents. 2001 Nov;1(3):219-35. Review.

PMID:
12678755
12.

Nucleic acids as targets for antitelomerase agents.

Alberti P, Lacroix L, Guittat L, Hélène C, Mergny JL.

Mini Rev Med Chem. 2003 Feb;3(1):23-36. Review.

PMID:
12570852
13.

Synthesis and binding properties of oligo-2'-deoxyribonucleotides conjugated with triple-helix-specific intercalators: benzo[e] and benzo[g] pyridoindoles.

Vinogradov S, Roig V, Sergueeva Z, Nguyen CH, Arimondo P, Thuong NT, Bisagni E, Sun JS, Hélène C, Asseline U.

Bioconjug Chem. 2003 Jan-Feb;14(1):120-35.

PMID:
12526701
14.

A directional nucleation-zipping mechanism for triple helix formation.

Alberti P, Arimondo PB, Mergny JL, Garestier T, Hélène C, Sun JS.

Nucleic Acids Res. 2002 Dec 15;30(24):5407-15.

15.

Coupling of a targeting peptide to plasmid DNA using a new type of padlock oligonucleotide.

Roulon T, Hélène C, Escudé C.

Bioconjug Chem. 2002 Sep-Oct;13(5):1134-9.

PMID:
12236796
16.

Directing topoisomerase I mediated DNA cleavage to specific sites by camptothecin tethered to minor- and major-groove ligands.

Arimondo PB, Bailly C, Boutorine AS, Ryabinin VA, Syniakov AN, Sun JS, Garestier T, Hélène C.

Angew Chem Int Ed Engl. 2001;40(16):3045-8. doi: 10.1002/1521-3773(20010817)40:16<3045::AID-ANIE3045>3.0.CO;2-A.

PMID:
12203644
17.

RNA hairpin invasion and ribosome elongation arrest by mixed base PNA oligomer.

Dias N, Sénamaud-Beaufort C, Forestier El El, Auvin C, Hélène C, Ester Saison-Behmoaras T.

J Mol Biol. 2002 Jul 12;320(3):489-501.

PMID:
12096905
18.

Formation of DNA triple helices by an oligonucleotide conjugated to a fluorescent ruthenium complex.

Grimm GN, Boutorine AS, Lincoln P, Nordén B, Hélène C.

Chembiochem. 2002 Apr 2;3(4):324-31.

PMID:
11933233
19.

Cell senescence and telomere shortening induced by a new series of specific G-quadruplex DNA ligands.

Riou JF, Guittat L, Mailliet P, Laoui A, Renou E, Petitgenet O, Mégnin-Chanet F, Hélène C, Mergny JL.

Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):2672-7. Epub 2002 Feb 19.

20.

Padlock oligonucleotides as a tool for labeling superhelical DNA.

Roulon T, Coulaud D, Delain E, Le Cam E, Hélène C, Escudé C.

Nucleic Acids Res. 2002 Feb 1;30(3):E12.

21.

Interaction of an acridine dimer with DNA quadruplex structures.

Alberti P, Ren J, Teulade-Fichou MP, Guittat L, Riou JF, Chaires J, Hélène C, Vigneron JP, Lehn JM, Mergny JL.

J Biomol Struct Dyn. 2001 Dec;19(3):505-13.

PMID:
11790148
22.

Site-directed inhibition of DNA replication by triple helix formation.

Diviacco S, Rapozzi V, Xodo L, Helene C, Quadrifoglio F, Giovannangeli C.

FASEB J. 2001 Dec;15(14):2660-8.

PMID:
11726542
23.

Design and optimization of camptothecin conjugates of triple helix-forming oligonucleotides for sequence-specific DNA cleavage by topoisomerase I.

Arimondo PB, Boutorine A, Baldeyrou B, Bailly C, Kuwahara M, Hecht SM, Sun JS, Garestier T, Hélène C.

J Biol Chem. 2002 Feb 1;277(5):3132-40. Epub 2001 Nov 27.

24.

Design and simple routes of synthesis of oligonucleotide conjugates for studies of DNA triple helix formation.

Grimm GN, Boutorine AS, Lincoln P, Hélène C.

Nucleosides Nucleotides Nucleic Acids. 2001 Apr-Jul;20(4-7):909-14.

PMID:
11563143
25.

Direct photocleavage of HIV-DNA by quinacridine derivatives triggered by triplex formation.

Teulade-Fichou MP, Perrin D, Boutorine A, Polverari D, Vigneron JP, Lehn JM, Sun JS, Garestier T, Helene C.

J Am Chem Soc. 2001 Sep 26;123(38):9283-92.

PMID:
11562210
26.

Triple helix-forming oligonucleotides conjugated to indolocarbazole poisons direct topoisomerase I-mediated DNA cleavage to a specific site.

Arimondo PB, Bailly C, Boutorine AS, Moreau P, Prudhomme M, Sun JS, Garestier T, Hélène C.

Bioconjug Chem. 2001 Jul-Aug;12(4):501-9.

PMID:
11459453
27.
28.

Synthesis and properties of triple helix-forming oligodeoxyribonucleotides containing 7-chloro-7-deaza-2'-deoxyguanosine.

Aubert Y, Perrouault L, Hélène C, Giovannangeli C, Asseline U.

Bioorg Med Chem. 2001 Jun;9(6):1617-24.

PMID:
11408181
30.

A Ligand-Modulated Padlock Oligonucleotide for Supercoiled Plasmids.

Roulon T, Hélène C, Escudé C.

Angew Chem Int Ed Engl. 2001 Apr 17;40(8):1523-1526. doi: 10.1002/1521-3773(20010417)40:8<1523::AID-ANIE1523>3.0.CO;2-A.

PMID:
29712369
31.

Triplex-forming molecules for modulation of DNA information processing.

Giovannangeli C, Hélène C.

Curr Opin Mol Ther. 2000 Jun;2(3):288-96. Review.

PMID:
11249623
32.

Telomerase inhibitors based on quadruplex ligands selected by a fluorescence assay.

Mergny JL, Lacroix L, Teulade-Fichou MP, Hounsou C, Guittat L, Hoarau M, Arimondo PB, Vigneron JP, Lehn JM, Riou JF, Garestier T, Hélène C.

Proc Natl Acad Sci U S A. 2001 Mar 13;98(6):3062-7.

33.

Ethidium derivatives bind to G-quartets, inhibit telomerase and act as fluorescent probes for quadruplexes.

Koeppel F, Riou JF, Laoui A, Mailliet P, Arimondo PB, Labit D, Petitgenet O, Hélène C, Mergny JL.

Nucleic Acids Res. 2001 Mar 1;29(5):1087-96.

34.
35.

Transcription inhibition induced by modified triple helix-forming oligonucleotides: a quantitative assay for evaluation in cells.

Faria M, Wood CD, White MR, Hélène C, Giovannangeli C.

J Mol Biol. 2001 Feb 9;306(1):15-24.

PMID:
11178890
37.

Pyrimidine morpholino oligonucleotides form a stable triple helix in the absence of magnesium ions.

Lacroix L, Arimondo PB, Takasugi M, Hélène C, Mergny JL.

Biochem Biophys Res Commun. 2000 Apr 13;270(2):363-9.

PMID:
10753631
38.

Phosphoramidate oligonucleotides as potent antisense molecules in cells and in vivo.

Faria M, Spiller DG, Dubertret C, Nelson JS, White MR, Scherman D, Hélène C, Giovannangeli C.

Nat Biotechnol. 2001 Jan;19(1):40-4.

PMID:
11135550
39.

Triplex technology takes off.

Giovannangeli C, Hélène C.

Nat Biotechnol. 2000 Dec;18(12):1245-6. No abstract available.

PMID:
11101800
40.

Linkage of a triple helix-forming oligonucleotide to amsacrine-4-carboxamide derivatives modulates the sequence-selectivity of topoisomerase II-mediated DNA cleavage.

Arimondo P, Bailly C, Boutorine A, Asseline U, Sun JS, Garestier T, Hélène C.

Nucleosides Nucleotides Nucleic Acids. 2000 Aug;19(8):1205-18.

PMID:
11097051
41.

The spherulites(TM): a promising carrier for oligonucleotide delivery.

Mignet N, Brun A, Degert C, Delord B, Roux D, Hélène C, Laversanne R, François JC.

Nucleic Acids Res. 2000 Aug 15;28(16):3134-42.

42.

A new family of sequence-specific DNA-cleaving agents directed by triple-helical structures: benzopyridoindole-EDTA conjugates.

Marchand C, Nguyen CH, Ward B, Sun JS, Bisagni E, Garestier T, Hélène C.

Chemistry. 2000 May 2;6(9):1559-63.

PMID:
10839173
43.

Recognition and cleavage of DNA by rebeccamycin- or benzopyridoquinoxaline conjugated of triple helix-forming oligonucleotides.

Arimondo PB, Moreau P, Boutorine A, Bailly C, Prudhomme M, Sun JS, Garestier T, Hélène C.

Bioorg Med Chem. 2000 Apr;8(4):777-84.

PMID:
10819166
44.

Triple helix formation and the antigene strategy for sequence-specific control of gene expression.

Praseuth D, Guieysse AL, Hélène C.

Biochim Biophys Acta. 1999 Dec 10;1489(1):181-206. Review.

PMID:
10807007
45.

Targeted inhibition of transcription elongation in cells mediated by triplex-forming oligonucleotides.

Faria M, Wood CD, Perrouault L, Nelson JS, Winter A, White MR, Helene C, Giovannangeli C.

Proc Natl Acad Sci U S A. 2000 Apr 11;97(8):3862-7.

46.

Unambiguous demonstration of triple-helix-directed gene modification.

Barre FX, Ait-Si-Ali S, Giovannangeli C, Luis R, Robin P, Pritchard LL, Helene C, Harel-Bellan A.

Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3084-8.

47.

Identification of two human nuclear proteins that recognise the cytosine-rich strand of human telomeres in vitro.

Lacroix L, Liénard H, Labourier E, Djavaheri-Mergny M, Lacoste J, Leffers H, Tazi J, Hélène C, Mergny JL.

Nucleic Acids Res. 2000 Apr 1;28(7):1564-75.

48.

Psoralen adducts induced by triplex-forming oligonucleotides are refractory to repair in HeLa cells.

Guieysse AL, Praseuth D, Giovannangeli C, Asseline U, Hélène C.

J Mol Biol. 2000 Feb 18;296(2):373-83.

PMID:
10669595
49.

Polyethylenimine but not cationic lipid improves antisense activity of 3'-capped phosphodiester oligonucleotides.

Dheur S, Dias N, van Aerschot A, Herdewijn P, Bettinger T, Rémy JS, Hélène C, Saison-Behmoaras ET.

Antisense Nucleic Acid Drug Dev. 1999 Dec;9(6):515-25.

PMID:
10645777
50.

Interaction of human DNA topoisomerase I with G-quartet structures.

Arimondo PB, Riou JF, Mergny JL, Tazi J, Sun JS, Garestier T, Hélène C.

Nucleic Acids Res. 2000 Dec 15;28(24):4832-8.

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