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Items: 1 to 50 of 83

1.

In vivo proteomics identifies the competence regulon and AliB oligopeptide transporter as pathogenic factors in pneumococcal meningitis.

Schmidt F, Kakar N, Meyer TC, Depke M, Masouris I, Burchhardt G, Gómez-Mejia A, Dhople V, Håvarstein LS, Sun Z, Moritz RL, Völker U, Koedel U, Hammerschmidt S.

PLoS Pathog. 2019 Jul 29;15(7):e1007987. doi: 10.1371/journal.ppat.1007987. eCollection 2019 Jul.

2.

CRISPR Interference for Rapid Knockdown of Essential Cell Cycle Genes in Lactobacillus plantarum.

Myrbråten IS, Wiull K, Salehian Z, Håvarstein LS, Straume D, Mathiesen G, Kjos M.

mSphere. 2019 Mar 20;4(2). pii: e00007-19. doi: 10.1128/mSphere.00007-19.

3.
4.

Structure of the Large Extracellular Loop of FtsX and Its Interaction with the Essential Peptidoglycan Hydrolase PcsB in Streptococcus pneumoniae.

Rued BE, Alcorlo M, Edmonds KA, Martínez-Caballero S, Straume D, Fu Y, Bruce KE, Wu H, Håvarstein LS, Hermoso JA, Winkler ME, Giedroc DP.

MBio. 2019 Jan 29;10(1). pii: e02622-18. doi: 10.1128/mBio.02622-18.

5.

Structure of the essential peptidoglycan amidotransferase MurT/GatD complex from Streptococcus pneumoniae.

Morlot C, Straume D, Peters K, Hegnar OA, Simon N, Villard AM, Contreras-Martel C, Leisico F, Breukink E, Gravier-Pelletier C, Le Corre L, Vollmer W, Pietrancosta N, Håvarstein LS, Zapun A.

Nat Commun. 2018 Aug 9;9(1):3180. doi: 10.1038/s41467-018-05602-w.

6.

CozEa and CozEb play overlapping and essential roles in controlling cell division in Staphylococcus aureus.

Stamsås GA, Myrbråten IS, Straume D, Salehian Z, Veening JW, Håvarstein LS, Kjos M.

Mol Microbiol. 2018 Sep;109(5):615-632. doi: 10.1111/mmi.13999. Epub 2018 Sep 26.

PMID:
29884993
7.

Identification of EloR (Spr1851) as a regulator of cell elongation in Streptococcus pneumoniae.

Stamsås GA, Straume D, Ruud Winther A, Kjos M, Frantzen CA, Håvarstein LS.

Mol Microbiol. 2017 Sep;105(6):954-967. doi: 10.1111/mmi.13748. Epub 2017 Jul 23.

8.

Evidence that pneumococcal WalK is regulated by StkP through protein-protein interaction.

Stamsås GA, Straume D, Salehian Z, Håvarstein LS.

Microbiology. 2017 Mar;163(3):383-399. doi: 10.1099/mic.0.000404. Epub 2017 Mar 29.

PMID:
27902439
9.

Overexpression of the fratricide immunity protein ComM leads to growth inhibition and morphological abnormalities in Streptococcus pneumoniae.

Straume D, Stamsås GA, Salehian Z, Håvarstein LS.

Microbiology. 2017 Jan;163(1):9-21. doi: 10.1099/mic.0.000402. Epub 2017 Feb 8.

PMID:
27902435
10.

Identification of pneumococcal proteins that are functionally linked to penicillin-binding protein 2b (PBP2b).

Straume D, Stamsås GA, Berg KH, Salehian Z, Håvarstein LS.

Mol Microbiol. 2017 Jan;103(1):99-116. doi: 10.1111/mmi.13543. Epub 2016 Oct 27.

11.

Natural transformation and genome evolution in Streptococcus pneumoniae.

Straume D, Stamsås GA, Håvarstein LS.

Infect Genet Evol. 2015 Jul;33:371-80. doi: 10.1016/j.meegid.2014.10.020. Epub 2014 Nov 4. Review.

PMID:
25445643
12.

Staphylococcus aureus competence genes: mapping of the SigH, ComK1 and ComK2 regulons by transcriptome sequencing.

Fagerlund A, Granum PE, Håvarstein LS.

Mol Microbiol. 2014 Nov;94(3):557-79. doi: 10.1111/mmi.12767. Epub 2014 Sep 22.

13.

Structural basis of PcsB-mediated cell separation in Streptococcus pneumoniae.

Bartual SG, Straume D, Stamsås GA, Muñoz IG, Alfonso C, Martínez-Ripoll M, Håvarstein LS, Hermoso JA.

Nat Commun. 2014 May 8;5:3842. doi: 10.1038/ncomms4842.

14.

The function of the transmembrane and cytoplasmic domains of pneumococcal penicillin-binding proteins 2x and 2b extends beyond that of simple anchoring devices.

Berg KH, Straume D, Håvarstein LS.

Microbiology. 2014 Aug;160(Pt 8):1585-98. doi: 10.1099/mic.0.078535-0. Epub 2014 Apr 30.

PMID:
24790090
15.

Effects of low PBP2b levels on cell morphology and peptidoglycan composition in Streptococcus pneumoniae R6.

Berg KH, Stamsås GA, Straume D, Håvarstein LS.

J Bacteriol. 2013 Oct;195(19):4342-54. doi: 10.1128/JB.00184-13. Epub 2013 Jul 19.

16.

CHiC, a new tandem affinity tag for the protein purification toolbox.

Stamsås GA, Håvarstein LS, Straume D.

J Microbiol Methods. 2013 Jan;92(1):59-63. doi: 10.1016/j.mimet.2012.11.003. Epub 2012 Nov 12.

PMID:
23154041
17.

Fratricide is essential for efficient gene transfer between pneumococci in biofilms.

Wei H, Håvarstein LS.

Appl Environ Microbiol. 2012 Aug;78(16):5897-905. doi: 10.1128/AEM.01343-12. Epub 2012 Jun 15.

18.

Attachment of capsular polysaccharide to the cell wall in Streptococcus pneumoniae.

Eberhardt A, Hoyland CN, Vollmer D, Bisle S, Cleverley RM, Johnsborg O, Håvarstein LS, Lewis RJ, Vollmer W.

Microb Drug Resist. 2012 Jun;18(3):240-55. doi: 10.1089/mdr.2011.0232. Epub 2012 Mar 20.

PMID:
22432711
19.

Properties and biological role of streptococcal fratricins.

Berg KH, Biørnstad TJ, Johnsborg O, Håvarstein LS.

Appl Environ Microbiol. 2012 May;78(10):3515-22. doi: 10.1128/AEM.00098-12. Epub 2012 Mar 9. Review.

20.

Deletion of the murein hydrolase CbpD reduces transformation efficiency in Streptococcus thermophilus.

Biørnstad TJ, Ohnstad HS, Håvarstein LS.

Microbiology. 2012 Apr;158(Pt 4):877-85. doi: 10.1099/mic.0.056150-0. Epub 2012 Jan 12.

PMID:
22241050
21.

LytF, a novel competence-regulated murein hydrolase in the genus Streptococcus.

Berg KH, Ohnstad HS, Håvarstein LS.

J Bacteriol. 2012 Feb;194(3):627-35. doi: 10.1128/JB.06273-11. Epub 2011 Nov 28.

22.

Peptide-regulated gene depletion system developed for use in Streptococcus pneumoniae.

Berg KH, Biørnstad TJ, Straume D, Håvarstein LS.

J Bacteriol. 2011 Oct;193(19):5207-15. doi: 10.1128/JB.05170-11. Epub 2011 Jul 29.

23.

ClpC acts as a negative regulator of competence in Streptococcus thermophilus.

Biørnstad TJ, Håvarstein LS.

Microbiology. 2011 Jun;157(Pt 6):1676-84. doi: 10.1099/mic.0.046425-0. Epub 2011 Mar 24.

PMID:
21436217
24.

Increasing competence in the genus Streptococcus.

Håvarstein LS.

Mol Microbiol. 2010 Nov;78(3):541-4.

25.

Pneumococcal CbpD is a murein hydrolase that requires a dual cell envelope binding specificity to kill target cells during fratricide.

Eldholm V, Johnsborg O, Straume D, Ohnstad HS, Berg KH, Hermoso JA, Håvarstein LS.

Mol Microbiol. 2010 May;76(4):905-17. doi: 10.1111/j.1365-2958.2010.07143.x. Epub 2010 Mar 25.

26.

The pneumococcal cell envelope stress-sensing system LiaFSR is activated by murein hydrolases and lipid II-interacting antibiotics.

Eldholm V, Gutt B, Johnsborg O, Brückner R, Maurer P, Hakenbeck R, Mascher T, Håvarstein LS.

J Bacteriol. 2010 Apr;192(7):1761-73. doi: 10.1128/JB.01489-09. Epub 2010 Jan 29.

27.

A food-grade site-directed mutagenesis system for Streptococcus thermophilus LMG 18311.

Blomqvist T, Steinmoen H, Håvarstein LS.

Lett Appl Microbiol. 2010 Mar;50(3):314-9. doi: 10.1111/j.1472-765X.2009.02794.x. Epub 2009 Dec 24.

28.

Pneumococcal LytR, a protein from the LytR-CpsA-Psr family, is essential for normal septum formation in Streptococcus pneumoniae.

Johnsborg O, Håvarstein LS.

J Bacteriol. 2009 Sep;191(18):5859-64. doi: 10.1128/JB.00724-09. Epub 2009 Jul 6.

29.

Regulation of natural genetic transformation and acquisition of transforming DNA in Streptococcus pneumoniae.

Johnsborg O, Håvarstein LS.

FEMS Microbiol Rev. 2009 May;33(3):627-42. Review.

30.

Fratricide in Streptococcus pneumoniae: contributions and role of the cell wall hydrolases CbpD, LytA and LytC.

Eldholm V, Johnsborg O, Haugen K, Ohnstad HS, Håvarstein LS.

Microbiology. 2009 Jul;155(Pt 7):2223-34. doi: 10.1099/mic.0.026328-0. Epub 2009 Apr 23.

PMID:
19389766
31.

Evolution of Streptococcus pneumoniae and its close commensal relatives.

Kilian M, Poulsen K, Blomqvist T, Håvarstein LS, Bek-Thomsen M, Tettelin H, Sørensen UB.

PLoS One. 2008 Jul 16;3(7):e2683. doi: 10.1371/journal.pone.0002683.

32.

A predatory mechanism dramatically increases the efficiency of lateral gene transfer in Streptococcus pneumoniae and related commensal species.

Johnsborg O, Eldholm V, Bjørnstad ML, Håvarstein LS.

Mol Microbiol. 2008 Jul;69(1):245-53. doi: 10.1111/j.1365-2958.2008.06288.x. Epub 2008 May 15.

33.

Natural genetic transformation: prevalence, mechanisms and function.

Johnsborg O, Eldholm V, Håvarstein LS.

Res Microbiol. 2007 Dec;158(10):767-78. Epub 2007 Oct 2. Review.

PMID:
17997281
34.

Competence-induced fratricide in streptococci.

Claverys JP, Martin B, Håvarstein LS.

Mol Microbiol. 2007 Jun;64(6):1423-33. Review. Erratum in: Mol Microbiol. 2007 Jul;65(1):230.

35.

Cannibalism and fratricide: mechanisms and raisons d'être.

Claverys JP, Håvarstein LS.

Nat Rev Microbiol. 2007 Mar;5(3):219-29. Review.

PMID:
17277796
36.
37.

BOX elements modulate gene expression in Streptococcus pneumoniae: impact on the fine-tuning of competence development.

Knutsen E, Johnsborg O, Quentin Y, Claverys JP, Håvarstein LS.

J Bacteriol. 2006 Dec;188(23):8307-12. Epub 2006 Sep 22.

38.

Pheromone-induced expression of recombinant proteins in Streptococcus thermophilus.

Blomqvist T, Steinmoen H, Håvarstein LS.

Arch Microbiol. 2006 Dec;186(6):465-73. Epub 2006 Aug 24.

PMID:
16932907
39.
40.

New insights into the pneumococcal fratricide: relationship to clumping and identification of a novel immunity factor.

Håvarstein LS, Martin B, Johnsborg O, Granadel C, Claverys JP.

Mol Microbiol. 2006 Feb;59(4):1297-307.

41.

Choline-binding protein D (CbpD) in Streptococcus pneumoniae is essential for competence-induced cell lysis.

Kausmally L, Johnsborg O, Lunde M, Knutsen E, Håvarstein LS.

J Bacteriol. 2005 Jul;187(13):4338-45.

42.
43.

Transformation and DNA repair: linkage by DNA recombination.

Tønjum T, Håvarstein LS, Koomey M, Seeberg E.

Trends Microbiol. 2004 Jan;12(1):1-4. Review.

PMID:
14700543
44.
45.

Production of class II bacteriocins by lactic acid bacteria; an example of biological warfare and communication.

Eijsink VG, Axelsson L, Diep DB, Håvarstein LS, Holo H, Nes IF.

Antonie Van Leeuwenhoek. 2002 Aug;81(1-4):639-54. Review.

PMID:
12448760
46.

Extracellular-peptide control of competence for genetic transformation in Streptococcus pneumoniae.

Claverys JP, Havarstein LS.

Front Biosci. 2002 Aug 1;7:d1798-814. Review.

PMID:
12133809
47.

Competence without a competence pheromone in a natural isolate of Streptococcus infantis.

Ween O, Teigen S, Gaustad P, Kilian M, Håvarstein LS.

J Bacteriol. 2002 Jul;184(13):3426-32.

48.
50.

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