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Items: 1 to 50 of 103

1.

N-locking stabilization of covalent helical peptides: Application to Bfl-1 antagonists.

Baggio C, Udompholkul P, Gambini L, Jossart J, Salem AF, Håkansson M, Perry JJP, Pellecchia M.

Chem Biol Drug Des. 2020 Jan 2. doi: 10.1111/cbdd.13661. [Epub ahead of print]

PMID:
31898401
2.

3-Substituted 1-Naphthamidomethyl-C-galactosyls Interact with Two Unique Sub-sites for High-Affinity and High-Selectivity Inhibition of Galectin-3.

Dahlqvist A, Mandal S, Peterson K, Håkansson M, Logan DT, Zetterberg FR, Leffler H, Nilsson UJ.

Molecules. 2019 Dec 12;24(24). pii: E4554. doi: 10.3390/molecules24244554.

3.

Crystal structures of the Bacillus subtilis prophage lytic cassette proteins XepA and YomS.

Freitag-Pohl S, Jasilionis A, Håkansson M, Svensson LA, Kovačič R, Welin M, Watzlawick H, Wang L, Altenbuchner J, Płotka M, Kaczorowska AK, Kaczorowski T, Nordberg Karlsson E, Al-Karadaghi S, Walse B, Aevarsson A, Pohl E.

Acta Crystallogr D Struct Biol. 2019 Nov 1;75(Pt 11):1028-1039. doi: 10.1107/S2059798319013330. Epub 2019 Nov 1.

4.

Structure-based design and in vivo anti-arthritic activity evaluation of a potent dipeptidyl cyclopropyl nitrile inhibitor of cathepsin C.

Korkmaz B, Lesner A, Wysocka M, Gieldon A, Håkansson M, Gauthier F, Logan DT, Jenne DE, Lauritzen C, Pedersen J.

Biochem Pharmacol. 2019 Jun;164:349-367. doi: 10.1016/j.bcp.2019.04.006. Epub 2019 Apr 9.

PMID:
30978322
5.

Discovery of three novel sesquiterpene synthases from Streptomyces chartreusis NRRL 3882 and crystal structure of an α-eudesmol synthase.

Kracht ON, Correia Cordeiro RS, Håkansson M, Stockmann J, Sander D, Bandow J, Senges CHR, Logan DT, Kourist R.

J Biotechnol. 2019 May 20;297:71-77. doi: 10.1016/j.jbiotec.2019.03.006. Epub 2019 Mar 27.

PMID:
30928538
6.

MM-131, a bispecific anti-Met/EpCAM mAb, inhibits HGF-dependent and HGF-independent Met signaling through concurrent binding to EpCAM.

Casaletto JB, Geddie ML, Abu-Yousif AO, Masson K, Fulgham A, Boudot A, Maiwald T, Kearns JD, Kohli N, Su S, Razlog M, Raue A, Kalra A, Håkansson M, Logan DT, Welin M, Chattopadhyay S, Harms BD, Nielsen UB, Schoeberl B, Lugovskoy AA, MacBeath G.

Proc Natl Acad Sci U S A. 2019 Apr 9;116(15):7533-7542. doi: 10.1073/pnas.1819085116. Epub 2019 Mar 21.

7.

Publisher Correction: A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.

Ladds MJGW, van Leeuwen IMM, Drummond CJ, Chu S, Healy AR, Popova G, Pastor Fernández A, Mollick T, Darekar S, Sedimbi SK, Nekulova M, Sachweh MCC, Campbell J, Higgins M, Tuck C, Popa M, Safont MM, Gelebart P, Fandalyuk Z, Thompson AM, Svensson R, Gustavsson AL, Johansson L, Färnegårdh K, Yngve U, Saleh A, Haraldsson M, D'Hollander ACA, Franco M, Zhao Y, Håkansson M, Walse B, Larsson K, Peat EM, Pelechano V, Lunec J, Vojtesek B, Carmena M, Earnshaw WC, McCarthy AR, Westwood NJ, Arsenian-Henriksson M, Lane DP, Bhatia R, McCormack E, Laín S.

Nat Commun. 2018 May 22;9(1):2071. doi: 10.1038/s41467-018-04198-5.

8.

Designing interactions by control of protein-ligand complex conformation: tuning arginine-arene interaction geometry for enhanced electrostatic protein-ligand interactions.

Noresson AL, Aurelius O, Öberg CT, Engström O, Sundin AP, Håkansson M, Stenström O, Akke M, Logan DT, Leffler H, Nilsson UJ.

Chem Sci. 2017 Dec 4;9(4):1014-1021. doi: 10.1039/c7sc04749e. eCollection 2018 Jan 28.

9.

A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.

Ladds MJGW, van Leeuwen IMM, Drummond CJ, Chu S, Healy AR, Popova G, Pastor Fernández A, Mollick T, Darekar S, Sedimbi SK, Nekulova M, Sachweh MCC, Campbell J, Higgins M, Tuck C, Popa M, Safont MM, Gelebart P, Fandalyuk Z, Thompson AM, Svensson R, Gustavsson AL, Johansson L, Färnegårdh K, Yngve U, Saleh A, Haraldsson M, D'Hollander ACA, Franco M, Zhao Y, Håkansson M, Walse B, Larsson K, Peat EM, Pelechano V, Lunec J, Vojtesek B, Carmena M, Earnshaw WC, McCarthy AR, Westwood NJ, Arsenian-Henriksson M, Lane DP, Bhatia R, McCormack E, Laín S.

Nat Commun. 2018 Mar 16;9(1):1107. doi: 10.1038/s41467-018-03441-3. Erratum in: Nat Commun. 2018 May 22;9(1):2071.

10.

Human rights versus societal norms: a mixed methods study among healthcare providers on social stigma related to adolescent abortion and contraceptive use in Kisumu, Kenya.

Håkansson M, Oguttu M, Gemzell-Danielsson K, Makenzius M.

BMJ Glob Health. 2018 Mar 5;3(2):e000608. doi: 10.1136/bmjgh-2017-000608. eCollection 2018.

11.

Synthesis of branched and linear 1,4-linked galactan oligosaccharides.

Andersen MCF, Boos I, Kinnaert C, Awan SI, Pedersen HL, Kračun SK, Lanz G, Rydahl MG, Kjærulff L, Håkansson M, Kimbung R, Logan DT, Gotfredsen CH, Willats WGT, Clausen MH.

Org Biomol Chem. 2018 Feb 14;16(7):1157-1162. doi: 10.1039/c7ob03035e.

PMID:
29367995
12.

Systematic Tuning of Fluoro-galectin-3 Interactions Provides Thiodigalactoside Derivatives with Single-Digit nM Affinity and High Selectivity.

Peterson K, Kumar R, Stenström O, Verma P, Verma PR, Håkansson M, Kahl-Knutsson B, Zetterberg F, Leffler H, Akke M, Logan DT, Nilsson UJ.

J Med Chem. 2018 Feb 8;61(3):1164-1175. doi: 10.1021/acs.jmedchem.7b01626. Epub 2018 Jan 11.

13.

Monosaccharide Derivatives with Low-Nanomolar Lectin Affinity and High Selectivity Based on Combined Fluorine-Amide, Phenyl-Arginine, Sulfur-π, and Halogen Bond Interactions.

Zetterberg FR, Peterson K, Johnsson RE, Brimert T, Håkansson M, Logan DT, Leffler H, Nilsson UJ.

ChemMedChem. 2018 Jan 22;13(2):133-137. doi: 10.1002/cmdc.201700744. Epub 2018 Jan 15.

PMID:
29194992
14.

Intact Protein Analysis at 21 Tesla and X-Ray Crystallography Define Structural Differences in Single Amino Acid Variants of Human Mitochondrial Branched-Chain Amino Acid Aminotransferase 2 (BCAT2).

Anderson LC, Håkansson M, Walse B, Nilsson CL.

J Am Soc Mass Spectrom. 2017 Sep;28(9):1796-1804. doi: 10.1007/s13361-017-1705-0. Epub 2017 Jul 5.

15.

Electrogenerated chemiluminescence induced by sequential hot electron and hole injection into aqueous electrolyte solution.

Salminen K, Kuosmanen P, Pusa M, Kulmala O, Håkansson M, Kulmala S.

Anal Chim Acta. 2016 Mar 17;912:24-31. doi: 10.1016/j.aca.2016.01.021. Epub 2016 Jan 27.

PMID:
26920769
16.

VIEWDEX: A STATUS REPORT.

Svalkvist A, Svensson S, Håkansson M, Båth M, Månsson LG.

Radiat Prot Dosimetry. 2016 Jun;169(1-4):38-45. doi: 10.1093/rpd/ncv543. Epub 2016 Jan 27. Review.

PMID:
26822421
17.

Health Care Utilization and Complications Rates among Users Of Hydrophilic-Coated Catheters.

Håkansson MA, Neovius K, Norrbäck M, Svensson J, Lundqvist T.

Urol Nurs. 2015 Sep-Oct;35(5):239-47.

PMID:
26630780
18.

Neutron crystallographic studies reveal hydrogen bond and water-mediated interactions between a carbohydrate-binding module and its bound carbohydrate ligand.

Fisher SZ, von Schantz L, Håkansson M, Logan DT, Ohlin M.

Biochemistry. 2015 Oct 27;54(42):6435-8. doi: 10.1021/acs.biochem.5b01058. Epub 2015 Oct 13.

PMID:
26451738
19.

Antiplasmodial and cytotoxic activities of the constituents of Turraea robusta and Turraea nilotica.

Irungu BN, Adipo N, Orwa JA, Kimani F, Heydenreich M, Midiwo JO, Martin Björemark P, Håkansson M, Yenesew A, Erdélyi M.

J Ethnopharmacol. 2015 Nov 4;174:419-25. doi: 10.1016/j.jep.2015.08.039. Epub 2015 Aug 28.

20.

Absolute Asymmetric Synthesis: Viedma Ripening of [Co(bpy)3](2+) and Solvent-Free Oxidation to [Co(bpy)3](3.).

Björemark PM, Jönsson J, Håkansson M.

Chemistry. 2015 Jul 20;21(30):10630-3. doi: 10.1002/chem.201500876. Epub 2015 Jun 17.

PMID:
26176794
21.

Spontaneous Generation of Chirality in Simple Diaryl Ethers.

Lennartson A, Hedström A, Håkansson M.

Chirality. 2015 Jul;27(7):425-9. doi: 10.1002/chir.22460. Epub 2015 May 31.

PMID:
26032449
22.

Absolute asymmetric synthesis of a tetrahedral silver complex.

Björemark PM, Olsson S, Kokoli T, Håkansson M.

Chemistry. 2015 Jun 8;21(24):8750-3. doi: 10.1002/chem.201500986. Epub 2015 May 4.

PMID:
25941015
23.

Absolute asymmetric synthesis: protected substrate oxidation.

Olsson S, Björemark PM, Kokoli T, Sundberg J, Lennartson A, McKenzie CJ, Håkansson M.

Chemistry. 2015 Mar 23;21(13):5211-9. doi: 10.1002/chem.201406354. Epub 2015 Feb 12.

PMID:
25677197
24.

Structure-function analysis of heterodimer formation, oligomerization, and receptor binding of the Staphylococcus aureus bi-component toxin LukGH.

Badarau A, Rouha H, Malafa S, Logan DT, Håkansson M, Stulik L, Dolezilkova I, Teubenbacher A, Gross K, Maierhofer B, Weber S, Jägerhofer M, Hoffman D, Nagy E.

J Biol Chem. 2015 Jan 2;290(1):142-56. doi: 10.1074/jbc.M114.598110. Epub 2014 Nov 3.

25.

Carbohydrate binding module recognition of xyloglucan defined by polar contacts with branching xyloses and CH-Π interactions.

von Schantz L, Håkansson M, Logan DT, Nordberg-Karlsson E, Ohlin M.

Proteins. 2014 Dec;82(12):3466-75. doi: 10.1002/prot.24700. Epub 2014 Oct 21.

PMID:
25302425
26.

Reuse versus single-use catheters for intermittent catheterization: what is safe and preferred? Review of current status.

Håkansson MÅ.

Spinal Cord. 2014 Jul;52(7):511-6. doi: 10.1038/sc.2014.79. Epub 2014 May 27. Review.

PMID:
24861702
27.

A versatile dinucleating ligand containing sulfonamide groups.

Sundberg J, Witt H, Cameron L, Håkansson M, Bendix J, McKenzie CJ.

Inorg Chem. 2014 Mar 17;53(6):2873-82. doi: 10.1021/ic402599e. Epub 2014 Feb 28.

PMID:
24580417
28.

Absolute asymmetric synthesis of enantiopure organozinc reagents, followed by highly enantioselective chlorination.

Olsson S, Lennartson A, Håkansson M.

Chemistry. 2013 Sep 9;19(37):12415-23. doi: 10.1002/chem.201301465. Epub 2013 Jul 23.

PMID:
23881740
29.

Supplementation by thylakoids to a high carbohydrate meal decreases feelings of hunger, elevates CCK levels and prevents postprandial hypoglycaemia in overweight women.

Stenblom EL, Montelius C, Östbring K, Håkansson M, Nilsson S, Rehfeld JF, Erlanson-Albertsson C.

Appetite. 2013 Sep;68:118-23. doi: 10.1016/j.appet.2013.04.022. Epub 2013 Apr 28.

30.

Evaluation of an improved method of simulating lung nodules in chest tomosynthesis.

Svalkvist A, Johnsson ÅA, Vikgren J, Håkansson M, Ullman G, Boijsen M, Fisichella V, Flinck A, Molnar D, Månsson LG, Båth M.

Acta Radiol. 2012 Oct 1;53(8):874-84. doi: 10.1258/ar.2012.120230. Epub 2012 Jul 31.

PMID:
22850573
31.

Structural basis for carbohydrate-binding specificity--a comparative assessment of two engineered carbohydrate-binding modules.

von Schantz L, Håkansson M, Logan DT, Walse B, Osterlin J, Nordberg-Karlsson E, Ohlin M.

Glycobiology. 2012 Jul;22(7):948-61. doi: 10.1093/glycob/cws063. Epub 2012 Mar 20.

PMID:
22434778
32.

Crystal structure of N-glycosylated human glypican-1 core protein: structure of two loops evolutionarily conserved in vertebrate glypican-1.

Svensson G, Awad W, Håkansson M, Mani K, Logan DT.

J Biol Chem. 2012 Apr 20;287(17):14040-51. doi: 10.1074/jbc.M111.322487. Epub 2012 Feb 20.

33.

Lean production and work-related musculoskeletal disorders: overviews of international and Swedish studies.

Brännmark M, Håkansson M.

Work. 2012;41 Suppl 1:2321-8. doi: 10.3233/WOR-2012-0459-2321. Review.

PMID:
22317062
34.

Crystal structures of the Chromobacterium violaceumω-transaminase reveal major structural rearrangements upon binding of coenzyme PLP.

Humble MS, Cassimjee KE, Håkansson M, Kimbung YR, Walse B, Abedi V, Federsel HJ, Berglund P, Logan DT.

FEBS J. 2012 Mar;279(5):779-92. doi: 10.1111/j.1742-4658.2012.08468.x. Epub 2012 Jan 23.

35.

The carbohydrate-binding site in galectin-3 is preorganized to recognize a sugarlike framework of oxygens: ultra-high-resolution structures and water dynamics.

Saraboji K, Håkansson M, Genheden S, Diehl C, Qvist J, Weininger U, Nilsson UJ, Leffler H, Ryde U, Akke M, Logan DT.

Biochemistry. 2012 Jan 10;51(1):296-306. doi: 10.1021/bi201459p. Epub 2011 Dec 7.

36.

Protein flexibility and conformational entropy in ligand design targeting the carbohydrate recognition domain of galectin-3.

Diehl C, Engström O, Delaine T, Håkansson M, Genheden S, Modig K, Leffler H, Ryde U, Nilsson UJ, Akke M.

J Am Chem Soc. 2010 Oct 20;132(41):14577-89. doi: 10.1021/ja105852y.

37.

Hydrogen-bonded network structures in dipyridinium, bis(2-methylpyridinium), bis(3-methylpyridinium) and bis(4-methylpyridinium) dioxidobis(oxydiacetato)uranate(VI).

Lennartson A, Håkansson M.

Acta Crystallogr C. 2010 Mar;66(Pt 3):m69-74. doi: 10.1107/S0108270109053839. Epub 2010 Feb 3.

38.

VIEWDEX: an efficient and easy-to-use software for observer performance studies.

Håkansson M, Svensson S, Zachrisson S, Svalkvist A, Båth M, Månsson LG.

Radiat Prot Dosimetry. 2010 Apr-May;139(1-3):42-51. doi: 10.1093/rpd/ncq057. Epub 2010 Mar 3.

PMID:
20200105
39.

Simulation of lung nodules in chest tomosynthesis.

Svalkvist A, Håkansson M, Ullman G, Båth M.

Radiat Prot Dosimetry. 2010 Apr-May;139(1-3):130-9. doi: 10.1093/rpd/ncp308. Epub 2010 Jan 21.

PMID:
20093269
40.

catena-Poly[[bis(acetylacetonato-kappa2O,O')cobalt(II)]-mu-1,3-di-4-pyridylpropane-kappa2N:N']: a one-dimensional coordination polymer capable of forming clathrates with prochiral aldehydes.

Lennartson A, Håkansson M.

Acta Crystallogr C. 2009 Aug;65(Pt 8):m325-7. doi: 10.1107/S0108270109027589. Epub 2009 Jul 30.

PMID:
19652313
41.

Total spontaneous resolution of five-coordinate complexes.

Lennartson A, Håkansson M.

Angew Chem Int Ed Engl. 2009;48(32):5869-71. doi: 10.1002/anie.200902206. No abstract available.

PMID:
19582750
42.

Diphenyldipyridinezinc(II): partial spontaneous resolution of an organometallic reagent.

Lennartson A, Håkansson M.

Acta Crystallogr C. 2009 May;65(Pt 5):m205-7. doi: 10.1107/S0108270109014127. Epub 2009 Apr 25.

PMID:
19407411
43.

Dipyridinium dichromate: an achiral compound forming chiral crystals.

Lennartson A, Håkansson M.

Acta Crystallogr C. 2009 May;65(Pt 5):m182-4. doi: 10.1107/S0108270109011469. Epub 2009 Apr 10.

PMID:
19407405
44.

A different approach to enantioselective organic synthesis: absolute asymmetric synthesis of organometallic reagents.

Lennartson A, Olsson S, Sundberg J, Håkansson M.

Angew Chem Int Ed Engl. 2009;48(17):3137-40. doi: 10.1002/anie.200806222.

PMID:
19322856
45.

Degradation of silicone grease by Grignard reagents: bis(mu-dimethylphenylsilanolato-kappa2O:O)bis[bromido(diethyl ether)magnesium(II)].

Lennartson A, Håkansson M.

Acta Crystallogr C. 2008 Jan;64(Pt 1):m8-9. doi: 10.1107/S0108270107057903. Epub 2007 Dec 14.

PMID:
18216447
46.

Investigation of commercial sodium cacodylate trihydrate: penta-mu-aqua-disodium(I) bis(dimethylarsenate) and di-mu-aqua-bis[triaquasodium(I)] bis(dimethylarsenate).

Lennartson A, Håkansson M.

Acta Crystallogr C. 2008 Jan;64(Pt 1):m13-6. doi: 10.1107/S0108270107055151. Epub 2007 Dec 14.

PMID:
18216428
47.

Slow atmospheric oxidation of diphenylzinc: di-mu-phenoxido-bis[(diethyl ether)phenylzinc(II)].

Lennartson A, Håkansson M.

Acta Crystallogr C. 2008 Jan;64(Pt 1):m10-2. doi: 10.1107/S0108270107057514. Epub 2007 Dec 14.

PMID:
18216427
48.

In search of conformationally chiral square-planar complexes: dichloridobis(2-methoxypyridine-kappaN)copper(II).

Lennartson A, Wiklund T, Håkansson M.

Acta Crystallogr C. 2007 Dec;63(Pt 12):m550-2. Epub 2007 Nov 14.

PMID:
18057591
49.

Facile synthesis of well-defined sodium hydridoalkylzincates(II).

Lennartson A, Håkansson M, Jagner S.

Angew Chem Int Ed Engl. 2007;46(35):6678-80. No abstract available.

PMID:
17665387
50.

Total spontaneous resolution of chiral covalent networks from stereochemically labile metal complexes.

Johansson A, Håkansson M, Jagner S.

Chemistry. 2005 Sep 5;11(18):5311-8.

PMID:
15999370

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