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Items: 22


Guidance for a causal comparative effectiveness analysis emulating a target trial based on big real world evidence: when to start statin treatment.

Kuehne F, Jahn B, Conrads-Frank A, Bundo M, Arvandi M, Endel F, Popper N, Endel G, Urach C, Gyimesi M, Murray EJ, Danaei G, Gaziano TA, Pandya A, Siebert U.

J Comp Eff Res. 2019 Sep;8(12):1013-1025. doi: 10.2217/cer-2018-0103. Epub 2019 Sep 12.


Targeting Myosin by Blebbistatin Derivatives: Optimization and Pharmacological Potential.

Rauscher AÁ, Gyimesi M, Kovács M, Málnási-Csizmadia A.

Trends Biochem Sci. 2018 Sep;43(9):700-713. doi: 10.1016/j.tibs.2018.06.006. Epub 2018 Jul 26. Review.


Human RAD51 rapidly forms intrinsically dynamic nucleoprotein filaments modulated by nucleotide binding state.

Špírek M, Mlcoušková J, Belán O, Gyimesi M, Harami GM, Molnár E, Novacek J, Kovács M, Krejci L.

Nucleic Acids Res. 2018 May 4;46(8):3967-3980. doi: 10.1093/nar/gky111.


RecQ helicase triggers a binding mode change in the SSB-DNA complex to efficiently initiate DNA unwinding.

Mills M, Harami GM, Seol Y, Gyimesi M, Martina M, Kovács ZJ, Kovács M, Neuman KC.

Nucleic Acids Res. 2017 Nov 16;45(20):11878-11890. doi: 10.1093/nar/gkx939.


Shuttling along DNA and directed processing of D-loops by RecQ helicase support quality control of homologous recombination.

Harami GM, Seol Y, In J, Ferencziová V, Martina M, Gyimesi M, Sarlós K, Kovács ZJ, Nagy NT, Sun Y, Vellai T, Neuman KC, Kovács M.

Proc Natl Acad Sci U S A. 2017 Jan 24;114(4):E466-E475. doi: 10.1073/pnas.1615439114. Epub 2017 Jan 9.


Recent adaptations of fluorescence techniques for the determination of mechanistic parameters of helicases and translocases.

Gyimesi M, Harami GM, Kocsis ZS, Kovács M.

Methods. 2016 Oct 1;108:24-39. doi: 10.1016/j.ymeth.2016.04.028. Epub 2016 Apr 29.


Mechanism of RecQ helicase mechanoenzymatic coupling reveals that the DNA interactions of the ADP-bound enzyme control translocation run terminations.

Sarlós K, Gyimesi M, Kele Z, Kovács M.

Nucleic Acids Res. 2015 Jan;43(2):1090-7. doi: 10.1093/nar/gku1333. Epub 2014 Dec 24.


Visualization of human Bloom's syndrome helicase molecules bound to homologous recombination intermediates.

Gyimesi M, Pires RH, Billington N, Sarlós K, Kocsis ZS, Módos K, Kellermayer MS, Kovács M.

FASEB J. 2013 Dec;27(12):4954-64. doi: 10.1096/fj.13-234088. Epub 2013 Sep 4.


From keys to bulldozers: expanding roles for winged helix domains in nucleic-acid-binding proteins.

Harami GM, Gyimesi M, Kovács M.

Trends Biochem Sci. 2013 Jul;38(7):364-71. doi: 10.1016/j.tibs.2013.04.006. Epub 2013 Jun 11. Review.


RecQ helicase translocates along single-stranded DNA with a moderate processivity and tight mechanochemical coupling.

Sarlós K, Gyimesi M, Kovács M.

Proc Natl Acad Sci U S A. 2012 Jun 19;109(25):9804-9. doi: 10.1073/pnas.1114468109. Epub 2012 Jun 4.


Complex activities of the human Bloom's syndrome helicase are encoded in a core region comprising the RecA and Zn-binding domains.

Gyimesi M, Harami GM, Sarlós K, Hazai E, Bikádi Z, Kovács M.

Nucleic Acids Res. 2012 May;40(9):3952-63. doi: 10.1093/nar/gks008. Epub 2012 Jan 16.


[Outpatient cardiac phase III rehabilitation at a Viennese institution - retrospective cohort study].

Piso B, Tüchler H, Gyimesi M, Kollmann I, Endel G, Wilbacher I, Kurz RW, Müller R.

Wien Med Wochenschr. 2011 May;161(9-10):263-71. doi: 10.1007/s10354-011-0897-3. German.


Functional adaptation of the switch-2 nucleotide sensor enables rapid processive translocation by myosin-5.

Nagy NT, Sakamoto T, Takács B, Gyimesi M, Hazai E, Bikádi Z, Sellers JR, Kovács M.

FASEB J. 2010 Nov;24(11):4480-90. doi: 10.1096/fj.10-163998. Epub 2010 Jul 14.


Myosin complexed with ADP and blebbistatin reversibly adopts a conformation resembling the start point of the working stroke.

Takács B, Billington N, Gyimesi M, Kintses B, Málnási-Csizmadia A, Knight PJ, Kovács M.

Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):6799-804. doi: 10.1073/pnas.0907585107. Epub 2010 Mar 29.


Processive translocation mechanism of the human Bloom's syndrome helicase along single-stranded DNA.

Gyimesi M, Sarlós K, Kovács M.

Nucleic Acids Res. 2010 Jul;38(13):4404-14. doi: 10.1093/nar/gkq145. Epub 2010 Mar 8.


Streamlined determination of processive run length and mechanochemical coupling of nucleic acid motor activities.

Gyimesi M, Sarlós K, Derényi I, Kovács M.

Nucleic Acids Res. 2010 Apr;38(7):e102. doi: 10.1093/nar/gkq014. Epub 2010 Jan 31.


[Chemonucleolysis and intradiscal electrothermal therapy: what is the current evidence?].

Felder-Puig R, Gyimesi M, Mittermayr T, Geiger-Gritsch S.

Rofo. 2009 Oct;181(10):936-44. doi: 10.1055/s-0028-1109573. Epub 2009 Sep 24. German.


The mechanism of the reverse recovery step, phosphate release, and actin activation of Dictyostelium myosin II.

Gyimesi M, Kintses B, Bodor A, Perczel A, Fischer S, Bagshaw CR, Málnási-Csizmadia A.

J Biol Chem. 2008 Mar 28;283(13):8153-63. doi: 10.1074/jbc.M708863200. Epub 2008 Jan 21.


Kinetic characterization of the function of myosin loop 4 in the actin-myosin interaction.

Gyimesi M, Tsaturyan AK, Kellermayer MS, Málnási-Csizmadia A.

Biochemistry. 2008 Jan 8;47(1):283-91. Epub 2007 Dec 8.


Reversible movement of switch 1 loop of myosin determines actin interaction.

Kintses B, Gyimesi M, Pearson DS, Geeves MA, Zeng W, Bagshaw CR, Málnási-Csizmadia A.

EMBO J. 2007 Jan 10;26(1):265-74.


Enzyme kinetics above denaturation temperature: a temperature-jump/stopped-flow apparatus.

Kintses B, Simon Z, Gyimesi M, Tóth J, Jelinek B, Niedetzky C, Kovács M, Málnási-Csizmadia A.

Biophys J. 2006 Dec 15;91(12):4605-10. Epub 2006 Sep 29.


Derivation of surface macroroughness parameters of a random rough surface from an optical interferometric measurement.

Gyimesi M, Richter P, Lorincz E.

Appl Opt. 1988 Mar 1;27(5):983-6. doi: 10.1364/AO.27.000983.


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