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Items: 8

1.

High Efficiency CRISPR/Cas9-mediated Gene Editing in Primary Human T-cells Using Mutant Adenoviral E4orf6/E1b55k "Helper" Proteins.

Gwiazda KS, Grier AE, Sahni J, Burleigh SM, Martin U, Yang JG, Popp NA, Krutein MC, Khan IF, Jacoby K, Jensen MC, Rawlings DJ, Scharenberg AM.

Mol Ther. 2016 Sep 29;24(9):1570-80. doi: 10.1038/mt.2016.105. Epub 2016 May 16.

2.

Efficient modification of CCR5 in primary human hematopoietic cells using a megaTAL nuclease and AAV donor template.

Sather BD, Romano Ibarra GS, Sommer K, Curinga G, Hale M, Khan IF, Singh S, Song Y, Gwiazda K, Sahni J, Jarjour J, Astrakhan A, Wagner TA, Scharenberg AM, Rawlings DJ.

Sci Transl Med. 2015 Sep 30;7(307):307ra156. doi: 10.1126/scitranslmed.aac5530.

3.

Extracellular Subunit Interactions Control Transitions between Functional States of Acid-sensing Ion Channel 1a.

Gwiazda K, Bonifacio G, Vullo S, Kellenberger S.

J Biol Chem. 2015 Jul 17;290(29):17956-66. doi: 10.1074/jbc.M115.641688. Epub 2015 Jun 12.

4.

Novel fluorescent genome editing reporters for monitoring DNA repair pathway utilization at endonuclease-induced breaks.

Kuhar R, Gwiazda KS, Humbert O, Mandt T, Pangallo J, Brault M, Khan I, Maizels N, Rawlings DJ, Scharenberg AM, Certo MT.

Nucleic Acids Res. 2014 Jan;42(1):e4. doi: 10.1093/nar/gkt872. Epub 2013 Oct 10.

5.

Coupling endonucleases with DNA end-processing enzymes to drive gene disruption.

Certo MT, Gwiazda KS, Kuhar R, Sather B, Curinga G, Mandt T, Brault M, Lambert AR, Baxter SK, Jacoby K, Ryu BY, Kiem HP, Gouble A, Paques F, Rawlings DJ, Scharenberg AM.

Nat Methods. 2012 Oct;9(10):973-5. doi: 10.1038/nmeth.2177. Epub 2012 Sep 2.

6.

Acute insulin signaling in pancreatic beta-cells is mediated by multiple Raf-1 dependent pathways.

Alejandro EU, Kalynyak TB, Taghizadeh F, Gwiazda KS, Rawstron EK, Jacob KJ, Johnson JD.

Endocrinology. 2010 Feb;151(2):502-12. doi: 10.1210/en.2009-0678. Epub 2010 Jan 7.

7.

Effects of palmitate on ER and cytosolic Ca2+ homeostasis in beta-cells.

Gwiazda KS, Yang TL, Lin Y, Johnson JD.

Am J Physiol Endocrinol Metab. 2009 Apr;296(4):E690-701. doi: 10.1152/ajpendo.90525.2008. Epub 2009 Jan 13.

8.

Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death.

Luciani DS, Gwiazda KS, Yang TL, Kalynyak TB, Bychkivska Y, Frey MH, Jeffrey KD, Sampaio AV, Underhill TM, Johnson JD.

Diabetes. 2009 Feb;58(2):422-32. doi: 10.2337/db07-1762. Epub 2008 Nov 25.

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