Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 146

1.

Recurrent intragenic rearrangements of EGFR and BRAF in soft tissue tumors of infants.

Wegert J, Vokuhl C, Collord G, Del Castillo Velasco-Herrera M, Farndon SJ, Guzzo C, Jorgensen M, Anderson J, Slater O, Duncan C, Bausenwein S, Streitenberger H, Ziegler B, Furtwängler R, Graf N, Stratton MR, Campbell PJ, Jones DT, Koelsche C, Pfister SM, Mifsud W, Sebire N, Sparber-Sauer M, Koscielniak E, Rosenwald A, Gessler M, Behjati S.

Nat Commun. 2018 Jun 18;9(1):2378. doi: 10.1038/s41467-018-04650-6.

2.

Interdomain Stabilization Impairs CD4 Binding and Improves Immunogenicity of the HIV-1 Envelope Trimer.

Zhang P, Gorman J, Geng H, Liu Q, Lin Y, Tsybovsky Y, Go EP, Dey B, Andine T, Kwon A, Patel M, Gururani D, Uddin F, Guzzo C, Cimbro R, Miao H, McKee K, Chuang GY, Martin L, Sironi F, Malnati MS, Desaire H, Berger EA, Mascola JR, Dolan MA, Kwong PD, Lusso P.

Cell Host Microbe. 2018 Jun 13;23(6):832-844.e6. doi: 10.1016/j.chom.2018.05.002.

PMID:
29902444
3.

A bipartite periplasmic receptor-diguanylate cyclase pair (XAC2383-XAC2382) in the bacterium Xanthomonas citri.

Teixeira RD, Guzzo CR, Arévalo SJ, Andrade MO, Abrahão J, de Souza RF, Farah CS.

J Biol Chem. 2018 Jul 6;293(27):10767-10781. doi: 10.1074/jbc.RA118.003475. Epub 2018 May 4.

PMID:
29728456
4.

Global Identification of Small Ubiquitin-related Modifier (SUMO) Substrates Reveals Crosstalk between SUMOylation and Phosphorylation Promotes Cell Migration.

Uzoma I, Hu J, Cox E, Xia S, Zhou J, Rho HS, Guzzo C, Paul C, Ajala O, Goodwin CR, Jeong J, Moore C, Zhang H, Meluh P, Blackshaw S, Matunis M, Qian J, Zhu H.

Mol Cell Proteomics. 2018 May;17(5):871-888. doi: 10.1074/mcp.RA117.000014. Epub 2018 Feb 8.

5.

The driver landscape of sporadic chordoma.

Tarpey PS, Behjati S, Young MD, Martincorena I, Alexandrov LB, Farndon SJ, Guzzo C, Hardy C, Latimer C, Butler AP, Teague JW, Shlien A, Futreal PA, Shah S, Bashashati A, Jamshidi F, Nielsen TO, Huntsman D, Baumhoer D, Brandner S, Wunder J, Dickson B, Cogswell P, Sommer J, Phillips JJ, Amary MF, Tirabosco R, Pillay N, Yip S, Stratton MR, Flanagan AM, Campbell PJ.

Nat Commun. 2017 Oct 12;8(1):890. doi: 10.1038/s41467-017-01026-0.

6.

Virion incorporation of integrin α4β7 facilitates HIV-1 infection and intestinal homing.

Guzzo C, Ichikawa D, Park C, Phillips D, Liu Q, Zhang P, Kwon A, Miao H, Lu J, Rehm C, Arthos J, Cicala C, Cohen MS, Fauci AS, Kehrl JH, Lusso P.

Sci Immunol. 2017 May 12;2(11). pii: eaam7341. doi: 10.1126/sciimmunol.aam7341.

7.

Structural and Enzymatic Characterization of a cAMP-Dependent Diguanylate Cyclase from Pathogenic Leptospira Species.

da Costa Vasconcelos FN, Maciel NK, Favaro DC, de Oliveira LC, Barbosa AS, Salinas RK, de Souza RF, Farah CS, Guzzo CR.

J Mol Biol. 2017 Jul 21;429(15):2337-2352. doi: 10.1016/j.jmb.2017.06.002. Epub 2017 Jun 7.

8.

Corrigendum: Quaternary contact in the initial interaction of CD4 with the HIV-1 envelope trimer.

Liu Q, Acharya P, Dolan MA, Zhang P, Guzzo C, Lu J, Kwon A, Gururani D, Miao H, Bylund T, Chuang GY, Druz A, Zhou T, Rice WJ, Wigge C, Carragher B, Potter CS, Kwong PD, Lusso P.

Nat Struct Mol Biol. 2017 Jun 6;24(6):553. doi: 10.1038/nsmb0617-553b. No abstract available.

PMID:
28586323
9.

Design of HIV Coreceptor Derived Peptides That Inhibit Viral Entry at Submicromolar Concentrations.

Bobyk KD, Mandadapu SR, Lohith K, Guzzo C, Bhargava A, Lusso P, Bewley CA.

Mol Pharm. 2017 Aug 7;14(8):2681-2689. doi: 10.1021/acs.molpharmaceut.7b00155. Epub 2017 Jul 13.

PMID:
28494151
10.

IL-27 enhances LPS-induced IL-1β in human monocytes and murine macrophages.

Petes C, Wynick C, Guzzo C, Mehta D, Logan S, Banfield BW, Basta S, Cooper A, Gee K.

J Leukoc Biol. 2017 Jul;102(1):83-94. doi: 10.1189/jlb.3A0316-098R. Epub 2017 Apr 4.

PMID:
28377398
11.

Global Analysis of SUMO-Binding Proteins Identifies SUMOylation as a Key Regulator of the INO80 Chromatin Remodeling Complex.

Cox E, Hwang W, Uzoma I, Hu J, Guzzo CM, Jeong J, Matunis MJ, Qian J, Zhu H, Blackshaw S.

Mol Cell Proteomics. 2017 May;16(5):812-823. doi: 10.1074/mcp.M116.063719. Epub 2017 Mar 2.

12.

Quaternary contact in the initial interaction of CD4 with the HIV-1 envelope trimer.

Liu Q, Acharya P, Dolan MA, Zhang P, Guzzo C, Lu J, Kwon A, Gururani D, Miao H, Bylund T, Chuang GY, Druz A, Zhou T, Rice WJ, Wigge C, Carragher B, Potter CS, Kwong PD, Lusso P.

Nat Struct Mol Biol. 2017 Apr;24(4):370-378. doi: 10.1038/nsmb.3382. Epub 2017 Feb 20. Erratum in: Nat Struct Mol Biol. 2017 Jun 6;24(6):553.

13.

Incidence of and Risk Factors for Skin Cancer in Organ Transplant Recipients in the United States.

Garrett GL, Blanc PD, Boscardin J, Lloyd AA, Ahmed RL, Anthony T, Bibee K, Breithaupt A, Cannon J, Chen A, Cheng JY, Chiesa-Fuxench Z, Colegio OR, Curiel-Lewandrowski C, Del Guzzo CA, Disse M, Dowd M, Eilers R Jr, Ortiz AE, Morris C, Golden SK, Graves MS, Griffin JR, Hopkins RS, Huang CC, Bae GH, Jambusaria A, Jennings TA, Jiang SI, Karia PS, Khetarpal S, Kim C, Klintmalm G, Konicke K, Koyfman SA, Lam C, Lee P, Leitenberger JJ, Loh T, Lowenstein S, Madankumar R, Moreau JF, Nijhawan RI, Ochoa S, Olasz EB, Otchere E, Otley C, Oulton J, Patel PH, Patel VA, Prabhu AV, Pugliano-Mauro M, Schmults CD, Schram S, Shih AF, Shin T, Soon S, Soriano T, Srivastava D, Stein JA, Sternhell-Blackwell K, Taylor S, Vidimos A, Wu P, Zajdel N, Zelac D, Arron ST.

JAMA Dermatol. 2017 Mar 1;153(3):296-303. doi: 10.1001/jamadermatol.2016.4920.

PMID:
28097368
14.

Tyrosine-sulfated V2 peptides inhibit HIV-1 infection via coreceptor mimicry.

Cimbro R, Peterson FC, Liu Q, Guzzo C, Zhang P, Miao H, Van Ryk D, Ambroggio X, Hurt DE, De Gioia L, Volkman BF, Dolan MA, Lusso P.

EBioMedicine. 2016 Aug;10:45-54. doi: 10.1016/j.ebiom.2016.06.037. Epub 2016 Jun 26.

15.

Stromal Cell-Derived Factor 2: A Novel Protein that Interferes in Endoplasmic Reticulum Stress Pathway in Human Placental Cells.

Lorenzon-Ojea AR, Guzzo CR, Kapidzic M, Fisher SJ, Bevilacqua E.

Biol Reprod. 2016 Aug;95(2):41. doi: 10.1095/biolreprod.115.138164. Epub 2016 Jun 22.

16.

The Xanthomonas type IV pilus.

Dunger G, Llontop E, Guzzo CR, Farah CS.

Curr Opin Microbiol. 2016 Apr;30:88-97. doi: 10.1016/j.mib.2016.01.007. Epub 2016 Feb 12. Review.

PMID:
26874963
17.

Brain Metabolism Correlates of the Free and Cued Selective Reminding Test in Mild Cognitive Impairment.

Caffarra P, Ghetti C, Ruffini L, Spallazzi M, Spotti A, Barocco F, Guzzo C, Marchi M, Gardini S.

J Alzheimers Dis. 2016;51(1):27-31. doi: 10.3233/JAD-150418.

PMID:
26836012
18.

Clinical and Cognitive Phenotype of Mild Cognitive Impairment Evolving to Dementia with Lewy Bodies.

Cagnin A, Bussè C, Gardini S, Jelcic N, Guzzo C, Gnoato F, Mitolo M, Ermani M, Caffarra P.

Dement Geriatr Cogn Dis Extra. 2015 Nov 24;5(3):442-9. doi: 10.1159/000441184. eCollection 2015 Sep-Dec.

19.

Engineering Metamorphic Chemokine Lymphotactin/XCL1 into the GAG-Binding, HIV-Inhibitory Dimer Conformation.

Fox JC, Tyler RC, Guzzo C, Tuinstra RL, Peterson FC, Lusso P, Volkman BF.

ACS Chem Biol. 2015 Nov 20;10(11):2580-8. doi: 10.1021/acschembio.5b00542. Epub 2015 Sep 2.

20.

Functional characterization of two SOS-regulated genes involved in mitomycin C resistance in Caulobacter crescentus.

Lopes-Kulishev CO, Alves IR, Valencia EY, Pidhirnyj MI, Fernández-Silva FS, Rodrigues TR, Guzzo CR, Galhardo RS.

DNA Repair (Amst). 2015 Sep;33:78-89. doi: 10.1016/j.dnarep.2015.06.009. Epub 2015 Jun 29.

PMID:
26162909
21.

Randomised clinical trial: a placebo-controlled study of intravenous golimumab induction therapy for ulcerative colitis.

Rutgeerts P, Feagan BG, Marano CW, Padgett L, Strauss R, Johanns J, Adedokun OJ, Guzzo C, Zhang H, Colombel JF, Reinisch W, Gibson PR, Sandborn WJ; PURSUIT-IV study group.

Aliment Pharmacol Ther. 2015 Sep;42(5):504-14. doi: 10.1111/apt.13291. Epub 2015 Jun 29.

22.

Structural Determinants for the Selective Anti-HIV-1 Activity of the All-β Alternative Conformer of XCL1.

Guzzo C, Fox JC, Miao H, Volkman BF, Lusso P.

J Virol. 2015 Sep;89(17):9061-7. doi: 10.1128/JVI.01285-15. Epub 2015 Jun 17.

23.

Characterization of HIV-1 entry inhibitors with broad activity against R5 and X4 viral strains.

Sironi F, Malnati M, Mongelli N, Cozzi P, Guzzo C, Ghezzi S, Martínez-Romero C, García-Sastre A, Lusso P, Jabes D, Biswas P.

J Transl Med. 2015 Apr 2;13:107. doi: 10.1186/s12967-015-0461-9.

24.

Identification of SUMO E3 ligase-specific substrates using the HuProt human proteome microarray.

Cox E, Uzoma I, Guzzo C, Jeong JS, Matunis M, Blackshaw S, Zhu H.

Methods Mol Biol. 2015;1295:455-63. doi: 10.1007/978-1-4939-2550-6_32.

25.

Bacterial killing via a type IV secretion system.

Souza DP, Oka GU, Alvarez-Martinez CE, Bisson-Filho AW, Dunger G, Hobeika L, Cavalcante NS, Alegria MC, Barbosa LR, Salinas RK, Guzzo CR, Farah CS.

Nat Commun. 2015 Mar 6;6:6453. doi: 10.1038/ncomms7453.

PMID:
25743609
26.

Phase 2a, randomized, double-blind, placebo-controlled, multicenter, parallel-group study of a H4 R-antagonist (JNJ-39758979) in Japanese adults with moderate atopic dermatitis.

Murata Y, Song M, Kikuchi H, Hisamichi K, Xu XL, Greenspan A, Kato M, Chiou CF, Kato T, Guzzo C, Thurmond RL, Ohtsuki M, Furue M.

J Dermatol. 2015 Feb;42(2):129-39. doi: 10.1111/1346-8138.12726. Epub 2014 Dec 9.

PMID:
25491792
27.

Xanthomonas citri subsp. citri type IV Pilus is required for twitching motility, biofilm development, and adherence.

Dunger G, Guzzo CR, Andrade MO, Jones JB, Farah CS.

Mol Plant Microbe Interact. 2014 Oct;27(10):1132-47. doi: 10.1094/MPMI-06-14-0184-R.

28.

Characterization of the SUMO-binding activity of the myeloproliferative and mental retardation (MYM)-type zinc fingers in ZNF261 and ZNF198.

Guzzo CM, Ringel A, Cox E, Uzoma I, Zhu H, Blackshaw S, Wolberger C, Matunis MJ.

PLoS One. 2014 Aug 18;9(8):e105271. doi: 10.1371/journal.pone.0105271. eCollection 2014.

29.

Stromal cell derived factor-2 (Sdf2): a novel protein expressed in mouse.

Lorenzon-Ojea AR, Caldeira W, Ribeiro AF, Fisher SJ, Guzzo CR, Bevilacqua E.

Int J Biochem Cell Biol. 2014 Aug;53:262-70. doi: 10.1016/j.biocel.2014.05.024. Epub 2014 May 28.

PMID:
24878610
30.

E2-mediated small ubiquitin-like modifier (SUMO) modification of thymine DNA glycosylase is efficient but not selective for the enzyme-product complex.

Coey CT, Fitzgerald ME, Maiti A, Reiter KH, Guzzo CM, Matunis MJ, Drohat AC.

J Biol Chem. 2014 May 30;289(22):15810-9. doi: 10.1074/jbc.M114.572081. Epub 2014 Apr 21.

31.

Tyrosine sulfation in the second variable loop (V2) of HIV-1 gp120 stabilizes V2-V3 interaction and modulates neutralization sensitivity.

Cimbro R, Gallant TR, Dolan MA, Guzzo C, Zhang P, Lin Y, Miao H, Van Ryk D, Arthos J, Gorshkova I, Brown PH, Hurt DE, Lusso P.

Proc Natl Acad Sci U S A. 2014 Feb 25;111(8):3152-7. doi: 10.1073/pnas.1314718111. Epub 2014 Feb 3.

32.

Impact of the timing and duration of weed control on the establishment of a rubber tree plantation.

Guzzo CD, Carvalho LB, Giancotti PR, Alves PL, Gonçalves EC, Martins JV.

An Acad Bras Cienc. 2014 Mar;86(1):495-504. doi: 10.1590/0001-37652014119113. Epub 2013 Dec 1.

33.

The CD8-derived chemokine XCL1/lymphotactin is a conformation-dependent, broad-spectrum inhibitor of HIV-1.

Guzzo C, Fox J, Lin Y, Miao H, Cimbro R, Volkman BF, Fauci AS, Lusso P.

PLoS Pathog. 2013;9(12):e1003852. doi: 10.1371/journal.ppat.1003852. Epub 2013 Dec 26.

34.

Pharmacokinetics of infliximab in children with moderate-to-severe ulcerative colitis: results from a randomized, multicenter, open-label, phase 3 study.

Adedokun OJ, Xu Z, Padgett L, Blank M, Johanns J, Griffiths A, Ford J, Zhou H, Guzzo C, Davis HM, Hyams J.

Inflamm Bowel Dis. 2013 Dec;19(13):2753-62. doi: 10.1097/01.MIB.0000435438.84365.f7.

PMID:
24193155
35.

Phenformin enhances the therapeutic benefit of BRAF(V600E) inhibition in melanoma.

Yuan P, Ito K, Perez-Lorenzo R, Del Guzzo C, Lee JH, Shen CH, Bosenberg MW, McMahon M, Cantley LC, Zheng B.

Proc Natl Acad Sci U S A. 2013 Nov 5;110(45):18226-31. doi: 10.1073/pnas.1317577110. Epub 2013 Oct 21.

36.

E2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1.

Wiener R, DiBello AT, Lombardi PM, Guzzo CM, Zhang X, Matunis MJ, Wolberger C.

Nat Struct Mol Biol. 2013 Sep;20(9):1033-9. doi: 10.1038/nsmb.2655. Epub 2013 Aug 18.

37.

Subcutaneous golimumab maintains clinical response in patients with moderate-to-severe ulcerative colitis.

Sandborn WJ, Feagan BG, Marano C, Zhang H, Strauss R, Johanns J, Adedokun OJ, Guzzo C, Colombel JF, Reinisch W, Gibson PR, Collins J, Järnerot G, Rutgeerts P; PURSUIT-Maintenance Study Group.

Gastroenterology. 2014 Jan;146(1):96-109.e1. doi: 10.1053/j.gastro.2013.06.010. Epub 2013 Jun 14.

PMID:
23770005
38.

Subcutaneous golimumab induces clinical response and remission in patients with moderate-to-severe ulcerative colitis.

Sandborn WJ, Feagan BG, Marano C, Zhang H, Strauss R, Johanns J, Adedokun OJ, Guzzo C, Colombel JF, Reinisch W, Gibson PR, Collins J, Järnerot G, Hibi T, Rutgeerts P; PURSUIT-SC Study Group.

Gastroenterology. 2014 Jan;146(1):85-95; quiz e14-5. doi: 10.1053/j.gastro.2013.05.048. Epub 2013 Jun 2.

PMID:
23735746
39.

Two RND proteins involved in heavy metal efflux in Caulobacter crescentus belong to separate clusters within proteobacteria.

Valencia EY, Braz VS, Guzzo C, Marques MV.

BMC Microbiol. 2013 Apr 11;13:79. doi: 10.1186/1471-2180-13-79.

40.

Expanding SUMO and ubiquitin-mediated signaling through hybrid SUMO-ubiquitin chains and their receptors.

Guzzo CM, Matunis MJ.

Cell Cycle. 2013 Apr 1;12(7):1015-7. doi: 10.4161/cc.24332. Epub 2013 Mar 19. No abstract available.

41.

Structure of the PilZ-FimXEAL-c-di-GMP Complex Responsible for the Regulation of Bacterial Type IV Pilus Biogenesis.

Guzzo CR, Dunger G, Salinas RK, Farah CS.

J Mol Biol. 2013 Jun 26;425(12):2174-97. doi: 10.1016/j.jmb.2013.03.021. Epub 2013 Mar 16.

42.

The TLR2 agonists lipoteichoic acid and Pam3CSK4 induce greater pro-inflammatory responses than inactivated Mycobacterium butyricum.

Gambhir V, Yildiz C, Mulder R, Siddiqui S, Guzzo C, Szewczuk M, Gee K, Basta S.

Cell Immunol. 2012 Nov;280(1):101-7. doi: 10.1016/j.cellimm.2012.12.001. Epub 2012 Dec 19.

PMID:
23298864
43.

IL-27 increases BST-2 expression in human monocytes and T cells independently of type I IFN.

Guzzo C, Jung M, Graveline A, Banfield BW, Gee K.

Sci Rep. 2012;2:974. doi: 10.1038/srep00974. Epub 2012 Dec 13.

44.

RNF4-dependent hybrid SUMO-ubiquitin chains are signals for RAP80 and thereby mediate the recruitment of BRCA1 to sites of DNA damage.

Guzzo CM, Berndsen CE, Zhu J, Gupta V, Datta A, Greenberg RA, Wolberger C, Matunis MJ.

Sci Signal. 2012 Dec 4;5(253):ra88. doi: 10.1126/scisignal.2003485.

45.

Ustekinumab induction and maintenance therapy in refractory Crohn's disease.

Sandborn WJ, Gasink C, Gao LL, Blank MA, Johanns J, Guzzo C, Sands BE, Hanauer SB, Targan S, Rutgeerts P, Ghosh S, de Villiers WJ, Panaccione R, Greenberg G, Schreiber S, Lichtiger S, Feagan BG; CERTIFI Study Group.

N Engl J Med. 2012 Oct 18;367(16):1519-28. doi: 10.1056/NEJMoa1203572.

46.

IL-27-induced gene expression is downregulated in HIV-infected subjects.

Guzzo C, Hopman WM, Che Mat NF, Wobeser W, Gee K.

PLoS One. 2012;7(9):e45706. doi: 10.1371/journal.pone.0045706. Epub 2012 Sep 25.

47.

SUMO, PTEN and Tumor Suppression.

Matunis MJ, Guzzo CM.

Pigment Cell Melanoma Res. 2012 Jul 31. doi: 10.1111/pcmr.12001. [Epub ahead of print]

48.

Development of the IL-12/23 antagonist ustekinumab in psoriasis: past, present, and future perspectives--an update.

Yeilding N, Szapary P, Brodmerkel C, Benson J, Plotnick M, Zhou H, Goyal K, Schenkel B, Giles-Komar J, Mascelli MA, Guzzo C.

Ann N Y Acad Sci. 2012 Aug;1263:1-12. doi: 10.1111/j.1749-6632.2012.06670.x. Epub 2012 Jul 23. Review.

PMID:
22823582
49.

The 3D structure and function of digestive cathepsin L-like proteinases of Tenebrio molitor larval midgut.

Beton D, Guzzo CR, Ribeiro AF, Farah CS, Terra WR.

Insect Biochem Mol Biol. 2012 Sep;42(9):655-64. doi: 10.1016/j.ibmb.2012.04.010. Epub 2012 May 30.

PMID:
22659439
50.

SUMO binding by the Epstein-Barr virus protein kinase BGLF4 is crucial for BGLF4 function.

Li R, Wang L, Liao G, Guzzo CM, Matunis MJ, Zhu H, Hayward SD.

J Virol. 2012 May;86(10):5412-21. doi: 10.1128/JVI.00314-12. Epub 2012 Mar 7.

Supplemental Content

Support Center