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Highly efficient Cas9-mediated transcriptional programming. Chavez A et al. Nat Methods. (2015)

AAV-mediated direct in vivo CRISPR screen identifies functional suppressors in glioblastoma. Chow RD et al. Nat Neurosci. (2017)

Self-Replicating RNA Vaccine Delivery to Dendritic Cells. Démoulins T et al. Methods Mol Biol. (2017)

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Items: 1 to 50 of 596


Systematic Immunotherapy Target Discovery Using Genome-Scale In Vivo CRISPR Screens in CD8 T Cells.

Dong MB, Wang G, Chow RD, Ye L, Zhu L, Dai X, Park JJ, Kim HR, Errami Y, Guzman CD, Zhou X, Chen KY, Renauer PA, Du Y, Shen J, Lam SZ, Zhou JJ, Lannin DR, Herbst RS, Chen S.

Cell. 2019 Aug 22;178(5):1189-1204.e23. doi: 10.1016/j.cell.2019.07.044.


Invariant NKT Cell-Mediated Modulation of ILC1s as a Tool for Mucosal Immune Intervention.

Trittel S, Vashist N, Ebensen T, Chambers BJ, Guzmán CA, Riese P.

Front Immunol. 2019 Aug 7;10:1849. doi: 10.3389/fimmu.2019.01849. eCollection 2019.


Self-reported diabetes and herpes zoster are associated with a weak humoral response to the seasonal influenza A H1N1 vaccine antigen among the elderly.

Akmatov MK, Riese P, Trittel S, May M, Prokein J, Illig T, Schindler C, Guzmán CA, Pessler F.

BMC Infect Dis. 2019 Jul 23;19(1):656. doi: 10.1186/s12879-019-4214-x.


A Network Involving Gut Microbiota, Circulating Bile Acids, and Hepatic Metabolism Genes That Protects Against Non-Alcoholic Fatty Liver Disease.

Petrov PD, García-Mediavilla MV, Guzmán C, Porras D, Nistal E, Martínez-Flórez S, Castell JV, González-Gallego J, Sánchez-Campos S, Jover R.

Mol Nutr Food Res. 2019 Jul 19:e1900487. doi: 10.1002/mnfr.201900487. [Epub ahead of print]


The STING activator c-di-AMP exerts superior adjuvant properties than the formulation poly(I:C)/CpG after subcutaneous vaccination with soluble protein antigen or DEC-205-mediated antigen targeting to dendritic cells.

Volckmar J, Knop L, Stegemann-Koniszewski S, Schulze K, Ebensen T, Guzmán CA, Bruder D.

Vaccine. 2019 Aug 14;37(35):4963-4974. doi: 10.1016/j.vaccine.2019.07.019. Epub 2019 Jul 15.


Novel colloidal associations of soyasaponins and lipid components (DPPC, cholesterol) as potential adjuvants for vaccines.

de Groot C, Müsken M, Bleckmann M, Ebensen T, Guzmán CA, Müller-Goymann CC.

Vaccine. 2019 Aug 14;37(35):4975-4986. doi: 10.1016/j.vaccine.2019.07.020. Epub 2019 Jul 15.


Genotype x environment interaction and genetic gain for grain yield and grain quality traits in Turkish spring wheat released between 1964 and 2010.

Nehe A, Akin B, Sanal T, Evlice AK, Ünsal R, Dinçer N, Demir L, Geren H, Sevim I, Orhan Ş, Yaktubay S, Ezici A, Guzman C, Morgounov A.

PLoS One. 2019 Jul 18;14(7):e0219432. doi: 10.1371/journal.pone.0219432. eCollection 2019.


Deep Kernel for Genomic and Near Infrared Predictions in Multi-Environment Breeding Trials.

Cuevas J, Montesinos-López O, Juliana P, Guzmán C, Pérez-Rodríguez P, González-Bucio J, Burgueño J, Montesinos-López A, Crossa J.

G3 (Bethesda). 2019 Jul 9. pii: g3.400493.2019. doi: 10.1534/g3.119.400493. [Epub ahead of print]


Appendiceal Carcinoid Tumors: Is There a Survival Advantage to Colectomy over Appendectomy?

Guzman C, Boddhula S, Panneerselvam N, Dodhia C, Hellenthal NJ, Monie D, Monzon JR, Kaufman T.

J Gastrointest Surg. 2019 Jul 3. doi: 10.1007/s11605-019-04306-w. [Epub ahead of print]


Dengue Virus in Bats from Córdoba and Sucre, Colombia.

Calderón A, Guzmán C, Mattar S, Rodriguez V, Martínez C, Violet L, Martínez J, Figueiredo LTM.

Vector Borne Zoonotic Dis. 2019 Jun 18. doi: 10.1089/vbz.2018.2324. [Epub ahead of print]


Systems Immunology Characterization of Novel Vaccine Formulations for Mycoplasma hyopneumoniae Bacterins.

Matthijs AMF, Auray G, Jakob V, García-Nicolás O, Braun RO, Keller I, Bruggman R, Devriendt B, Boyen F, Guzman CA, Michiels A, Haesebrouck F, Collin N, Barnier-Quer C, Maes D, Summerfield A.

Front Immunol. 2019 May 24;10:1087. doi: 10.3389/fimmu.2019.01087. eCollection 2019.


Correction to: Incidence and Risk Factors for Cholelithiasis After Bariatric Surgery.

Guzmán M H, Sepúlveda M, Rosso N, San Martin AE, Guzmán F, Guzmán C H.

Obes Surg. 2019 Aug;29(8):2718. doi: 10.1007/s11695-019-03950-0.


Liver disease in pregnancy: Medical aspects and their implications for mother and child.

García-Romero CS, Guzman C, Cervantes A, Cerbón M.

Ann Hepatol. 2019 Jul - Aug;18(4):553-562. doi: 10.1016/j.aohep.2019.04.009. Epub 2019 May 6. Review.


Cohort profile: The LoewenKIDS Study - life-course perspective on infections, the microbiome and the development of the immune system in early childhood.

Gottschick C, Raupach-Rosin H, Langer S, Hassan L, Horn J, Dorendorf E, Caputo M, Bittner M, Beier L, Rübsamen N, Schlinkmann K, Zoch B, Guzman CA, Hansen G, Heselich V, Holzapfel E, Hübner J, Pietschmann T, Pieper DH, Pletz M, Riese P, Schmidt-Pokrzywniak A, Hartwig S, von Kaisenberg C, Aydogdu M, Buhles M, Dressler F, Eberl W, Haase R, von Koch FE, Feidicker S, Frambach T, Franz HGB, Guthmann F, Koch HG, Seeger S, Oberhoff C, Pauker W, Petry KU, Schild RL, Tchirikov M, Röhrig E, Karch A, Mikolajczyk R.

Int J Epidemiol. 2019 Apr 1. pii: dyz069. doi: 10.1093/ije/dyz069. [Epub ahead of print] No abstract available.


Frugivorous bats in the Colombian Caribbean region are reservoirs of the rabies virus.

Calderón A, Guzmán C, Mattar S, Rodríguez V, Acosta A, Martínez C.

Ann Clin Microbiol Antimicrob. 2019 Mar 19;18(1):11. doi: 10.1186/s12941-019-0308-y.


The Combination Vaccine Adjuvant System Alum/c-di-AMP Results in Quantitative and Qualitative Enhanced Immune Responses Post Immunization.

Ebensen T, Delandre S, Prochnow B, Guzmán CA, Schulze K.

Front Cell Infect Microbiol. 2019 Feb 19;9:31. doi: 10.3389/fcimb.2019.00031. eCollection 2019.


Cohort profile: The LoewenKIDS Study - life-course perspective on infections, the microbiome and the development of the immune system in early childhood.

Gottschick C, Raupach-Rosin H, Langer S, Hassan L, Horn J, Dorendorf E, Caputo M, Bittner M, Beier L, Rübsamen N, Schlinkmann K, Zoch B, Guzman CA, Hansen G, Heselich V, Holzapfel E, Hübner J, Pietschmann T, Pieper DH, Pletz M, Riese P, Schmidt-Pokrzywniak A, Hartwig S, von Kaisenberg C, Aydogdu M, Buhles M, Dressler F, Eberl W, Haase R, Edler von Koch F, Feidicker S, Frambach T, Franz HGB, Guthmann F, Koch HG, Seeger S, Oberhoff C, Pauker W, Petry KU, Schild RL, Tchirikov M, Röhrig E, Mikolajczyk R.

Int J Epidemiol. 2019 Feb 27. pii: dyz001. doi: 10.1093/ije/dyz001. [Epub ahead of print] No abstract available.


Inhibition of soluble TNFα prevents adverse atrial remodeling and atrial arrhythmia susceptibility induced in mice by endurance exercise.

Lakin R, Polidovitch N, Yang S, Guzman C, Gao X, Wauchop M, Burns J, Izaddoustdar F, Backx PH.

J Mol Cell Cardiol. 2019 Apr;129:165-173. doi: 10.1016/j.yjmcc.2019.01.012. Epub 2019 Feb 21.


Assessing Genetic Diversity to Breed Competitive Biofortified Wheat With Enhanced Grain Zn and Fe Concentrations.

Velu G, Crespo Herrera L, Guzman C, Huerta J, Payne T, Singh RP.

Front Plant Sci. 2019 Jan 10;9:1971. doi: 10.3389/fpls.2018.01971. eCollection 2018.


Implementation of Virtual Sensors for Monitoring Temperature in Greenhouses Using CFD and Control.

Guzmán CH, Carrera JL, Durán HA, Berumen J, Ortiz AA, Guirette OA, Arroyo A, Brizuela JA, Gómez F, Blanco A, Azcaray HR, Hernández M.

Sensors (Basel). 2018 Dec 24;19(1). pii: E60. doi: 10.3390/s19010060.


Eco-epidemiology of the Venezuelan equine encephalitis virus in bats of Córdoba and Sucre, Colombia.

Guzmán C, Calderón A, Martinez C, Oviedo M, Mattar S.

Acta Trop. 2019 Mar;191:178-184. doi: 10.1016/j.actatropica.2018.12.016. Epub 2018 Dec 19.


Signatures of T and B Cell Development, Functional Responses and PD-1 Upregulation After HCMV Latent Infections and Reactivations in Nod.Rag.Gamma Mice Humanized With Cord Blood CD34+ Cells.

Theobald SJ, Khailaie S, Meyer-Hermann M, Volk V, Olbrich H, Danisch S, Gerasch L, Schneider A, Sinzger C, Schaudien D, Lienenklaus S, Riese P, Guzman CA, Figueiredo C, von Kaisenberg C, Spineli LM, Glaesener S, Meyer-Bahlburg A, Ganser A, Schmitt M, Mach M, Messerle M, Stripecke R.

Front Immunol. 2018 Nov 22;9:2734. doi: 10.3389/fimmu.2018.02734. eCollection 2018.


Prenatal exposure to persistent organic compounds and their association with anogenital distance in infants.

Loreto-Gómez C, Farías P, Moreno-Macías H, Guzmán C, Riojas-Rodríguez H.

Reprod Biomed Online. 2018 Dec;37(6):732-740. doi: 10.1016/j.rbmo.2018.09.008. Epub 2018 Oct 6.


A REDCap application that links researchers, animal facility staff and members of the IACUC in animal health monitoring.

Carvajal C, Vallejos C, Lemaitre D, Ruiz J, Guzmán C, Aguilera V, Baño D, Calligaris SD.

Lab Anim. 2018 Dec 8:23677218815723. doi: 10.1177/0023677218815723. [Epub ahead of print]


Diffuse reflectance spectroscopy accurately discriminates early and advanced grades of fatty liver in mice.

Arista Romeu EJ, Escobedo G, Campos-Espinosa A, Romero-Bello II, Moreno-González J, Fabila-Bustos DA, Reed AV, Isakina SS, Vázquez JMR, Guzmán C.

J Biomed Opt. 2018 Nov;23(11):1-8. doi: 10.1117/1.JBO.23.11.115005.


Breeding-assisted genomics: Applying meta-GWAS for milling and baking quality in CIMMYT wheat breeding program.

Battenfield SD, Sheridan JL, Silva LDCE, Miclaus KJ, Dreisigacker S, Wolfinger RD, Peña RJ, Singh RP, Jackson EW, Fritz AK, Guzmán C, Poland JA.

PLoS One. 2018 Nov 29;13(11):e0204757. doi: 10.1371/journal.pone.0204757. eCollection 2018.


Functional and immunogenic characterization of diverse HCV glycoprotein E2 variants.

Khera T, Behrendt P, Bankwitz D, Brown RJP, Todt D, Doepke M, Khan AG, Schulze K, Law J, Logan M, Hockman D, Wong JAJ, Dold L, Gonzalez-Motos V, Spengler U, Viejo-Borbolla A, Ströh LJ, Krey T, Tarr AW, Steinmann E, Manns MP, Klein F, Guzman CA, Marcotrigiano J, Houghton M, Pietschmann T.

J Hepatol. 2019 Apr;70(4):593-602. doi: 10.1016/j.jhep.2018.11.003. Epub 2018 Nov 13.


Angiopoietin-Like Protein 8 Is a Novel Vitamin D Receptor Target Gene Involved in Nonalcoholic Fatty Liver Pathogenesis.

García-Monzón C, Petrov PD, Rey E, Marañón P, Del Pozo-Maroto E, Guzmán C, Rodríguez de Cía J, Casado-Collado AJ, Vargas-Castrillón J, Saez A, Miquilena-Colina ME, Lo Iacono O, Castell JV, González-Rodríguez Á, Jover R.

Am J Pathol. 2018 Dec;188(12):2800-2810. doi: 10.1016/j.ajpath.2018.07.028. Epub 2018 Sep 22.


Respiratory Bordetella bronchiseptica Carriage is Associated with Broad Phenotypic Alterations of Peripheral CD4⁺CD25⁺ T Cells and Differentially Affects Immune Responses to Secondary Non-Infectious and Infectious Stimuli in Mice.

Jeron A, Boehme JD, Volckmar J, Gereke M, Yevsa T, Geffers R, Guzmán CA, Schreiber J, Stegemann-Koniszewski S, Bruder D.

Int J Mol Sci. 2018 Sep 1;19(9). pii: E2602. doi: 10.3390/ijms19092602.


Self-Amplifying Replicon RNA Delivery to Dendritic Cells by Cationic Lipids.

Englezou PC, Sapet C, Démoulins T, Milona P, Ebensen T, Schulze K, Guzman CA, Poulhes F, Zelphati O, Ruggli N, McCullough KC.

Mol Ther Nucleic Acids. 2018 Sep 7;12:118-134. doi: 10.1016/j.omtn.2018.04.019. Epub 2018 May 4.


Junction-based lamellipodia drive endothelial cell rearrangements in vivo via a VE-cadherin-F-actin based oscillatory cell-cell interaction.

Paatero I, Sauteur L, Lee M, Lagendijk AK, Heutschi D, Wiesner C, Guzmán C, Bieli D, Hogan BM, Affolter M, Belting HG.

Nat Commun. 2018 Aug 31;9(1):3545. doi: 10.1038/s41467-018-05851-9.


ProLIF - quantitative integrin protein-protein interactions and synergistic membrane effects on proteoliposomes.

De Franceschi N, Miihkinen M, Hamidi H, Alanko J, Mai A, Picas L, Guzmán C, Lévy D, Mattjus P, Goult BT, Goud B, Ivaska J.

J Cell Sci. 2018 Aug 20;132(4). pii: jcs214270. doi: 10.1242/jcs.214270.


Changes in Heart Rate and Its Regulation by the Autonomic Nervous System Do Not Differ Between Forced and Voluntary Exercise in Mice.

Lakin R, Guzman C, Izaddoustdar F, Polidovitch N, Goodman JM, Backx PH.

Front Physiol. 2018 Jul 16;9:841. doi: 10.3389/fphys.2018.00841. eCollection 2018.


Adipose tissue derived-factors impaired pancreatic β-cell function in diabetes.

Rebuffat SA, Sidot E, Guzman C, Azay-Milhau J, Jover B, Lajoix AD, Peraldi-Roux S.

Biochim Biophys Acta Mol Basis Dis. 2018 Oct;1864(10):3378-3387. doi: 10.1016/j.bbadis.2018.07.024. Epub 2018 Jul 23.


Mannose Metabolism Is Essential for Th1 Cell Differentiation and IFN-γ Production.

Zygmunt BM, Węgrzyn A, Gajska W, Yevsa T, Chodaczek G, Guzmán CA.

J Immunol. 2018 Sep 1;201(5):1400-1411. doi: 10.4049/jimmunol.1700042. Epub 2018 Jul 20.


Rapid In Vivo Assessment of Adjuvant's Cytotoxic T Lymphocytes Generation Capabilities for Vaccine Development.

Lirussi D, Ebensen T, Schulze K, Reinhard E, Trittel S, Riese P, Prochnow B, Guzmán CA.

J Vis Exp. 2018 Jun 19;(136). doi: 10.3791/57401.


Large-scale production of megakaryocytes in microcarrier-supported stirred suspension bioreactors.

Eicke D, Baigger A, Schulze K, Latham SL, Halloin C, Zweigerdt R, Guzman CA, Blasczyk R, Figueiredo C.

Sci Rep. 2018 Jul 5;8(1):10146. doi: 10.1038/s41598-018-28459-x.


Targeting β1-integrin inhibits vascular leakage in endotoxemia.

Hakanpaa L, Kiss EA, Jacquemet G, Miinalainen I, Lerche M, Guzmán C, Mervaala E, Eklund L, Ivaska J, Saharinen P.

Proc Natl Acad Sci U S A. 2018 Jul 10;115(28):E6467-E6476. doi: 10.1073/pnas.1722317115. Epub 2018 Jun 25.


Transcriptome analysis of the reef-building octocoral, Heliopora coerulea.

Guzman C, Shinzato C, Lu TM, Conaco C.

Sci Rep. 2018 May 30;8(1):8397. doi: 10.1038/s41598-018-26718-5.


Coding variants in PNPLA3 and TM6SF2 are risk factors for hepatic steatosis and elevated serum alanine aminotransferases caused by a glucagon receptor antagonist.

Guzman CB, Duvvuru S, Akkari A, Bhatnagar P, Battioui C, Foster W, Zhang XM, Shankar SS, Deeg MA, Chalasani N, Hardy TA, Kazda CM, Pillai SG.

Hepatol Commun. 2018 Mar 23;2(5):561-570. doi: 10.1002/hep4.1171. eCollection 2018 May.


Community strengthening and mental health system linking after flooding in two informal human settlements in Peru: a model for small-scale disaster response.

Contreras C, Aguilar M, Eappen B, Guzmán C, Carrasco P, Millones AK, Galea JT.

Glob Ment Health (Camb). 2018 Mar 12;5:e11. doi: 10.1017/gmh.2017.33. eCollection 2018.


Influenza-Activated ILC1s Contribute to Antiviral Immunity Partially Influenced by Differential GITR Expression.

Vashist N, Trittel S, Ebensen T, Chambers BJ, Guzmán CA, Riese P.

Front Immunol. 2018 Mar 22;9:505. doi: 10.3389/fimmu.2018.00505. eCollection 2018.


Antiproliferative and Antioxidant Activities of Wild Boletales Mushrooms from France.

Morel S, Arnould S, Vitou M, Boudard F, Guzman C, Poucheret P, Fons F, Rapior S.

Int J Med Mushrooms. 2018;20(1):13-29. doi: 10.1615/IntJMedMushrooms.2018025329.


Fluorescence from a single Symbiodinium cell.

Guzman C, Han X, Shoguchi E, Chormaic SN.

Methods Appl Fluoresc. 2018 Apr 18;6(3):035003. doi: 10.1088/2050-6120/aaba89.


A phase 3 multicenter, open-label, prospective study designed to evaluate the effectiveness and ease of use of nasal glucagon in the treatment of moderate and severe hypoglycemia in children and adolescents with type 1 diabetes in the home or school setting.

Deeb LC, Dulude H, Guzman CB, Zhang S, Reiner BJ, Piché CA, Pradhan S, Zhang XM.

Pediatr Diabetes. 2018 Aug;19(5):1007-1013. doi: 10.1111/pedi.12668. Epub 2018 Mar 22.


Prospective study evaluating the use of nasal glucagon for the treatment of moderate to severe hypoglycaemia in adults with type 1 diabetes in a real-world setting.

Seaquist ER, Dulude H, Zhang XM, Rabasa-Lhoret R, Tsoukas GM, Conway JR, Weisnagel SJ, Gerety G, Woo VC, Zhang S, Carballo D, Pradhan S, Piché CA, Guzman CB.

Diabetes Obes Metab. 2018 May;20(5):1316-1320. doi: 10.1111/dom.13278. Epub 2018 Mar 22.


Mapping a functional cancer genome atlas of tumor suppressors in mouse liver using AAV-CRISPR-mediated direct in vivo screening.

Wang G, Chow RD, Ye L, Guzman CD, Dai X, Dong MB, Zhang F, Sharp PA, Platt RJ, Chen S.

Sci Adv. 2018 Feb 28;4(2):eaao5508. doi: 10.1126/sciadv.aao5508. eCollection 2018 Feb.


Respiratory Influenza A Virus Infection Triggers Local and Systemic Natural Killer Cell Activation via Toll-Like Receptor 7.

Stegemann-Koniszewski S, Behrens S, Boehme JD, Hochnadel I, Riese P, Guzmán CA, Kröger A, Schreiber J, Gunzer M, Bruder D.

Front Immunol. 2018 Feb 13;9:245. doi: 10.3389/fimmu.2018.00245. eCollection 2018.


The Institution of Sociological Theory in Canada.

Guzman C, Silver D.

Can Rev Sociol. 2018 Feb;55(1):9-39. doi: 10.1111/cars.12177.


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