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Measurement of Treatment Effects Require Instruments Responsive to Change Based on the Minimal Important Difference.

Johnston BC, Guyatt GH.

Clin Chem. 2019 Feb 15. pii: clinchem.2018.290817. doi: 10.1373/clinchem.2018.290817. [Epub ahead of print] No abstract available.


GRADE Guidelines: 22. The GRADE approach for tests and strategies - from test accuracy to patient important outcomes and recommendations.

Schünemann HJ, Mustafa RA, Brozek J, Santesso N, Bossuyt PM, Steingart KR, Leeflang M, Lange S, Trenti T, Langendam M, Scholten R, Hooft L, Murad MH, Jaeschke R, Rutjes A, Singh J, Helfand M, Glasziou P, Rodriguez IA, Akl EA, Deeks JJ, Guyatt GH; GRADE Working Group.

J Clin Epidemiol. 2019 Feb 7. pii: S0895-4356(17)31095-8. doi: 10.1016/j.jclinepi.2019.02.003. [Epub ahead of print]


Antibiotic Prophylaxis in the Management of Open Fractures: A Systematic Survey of Current Practice and Recommendations.

Chang Y, Bhandari M, Zhu KL, Mirza RD, Ren M, Kennedy SA, Negm A, Bhatnagar N, Naji FN, Milovanovic L, Fei Y, Agarwal A, Kamran R, Cho SM, Schandelmaier S, Wang L, Jin L, Hu S, Zhao Y, Lopes LC, Wang M, Petrisor B, Ristevski B, Siemieniuk RAC, Guyatt GH.

JBJS Rev. 2019 Feb;7(2):e1. doi: 10.2106/JBJS.RVW.17.00197.


Assessing Patient Perspectives on Receiving Bad News: A Survey of 1337 Patients With Life-Changing Diagnoses.

Mirza RD, Ren M, Agarwal A, Guyatt GH.

AJOB Empir Bioeth. 2018 Dec 31:1-8. doi: 10.1080/23294515.2018.1543218. [Epub ahead of print]


Opioids for Chronic Noncancer Pain: A Systematic Review and Meta-analysis.

Busse JW, Wang L, Kamaleldin M, Craigie S, Riva JJ, Montoya L, Mulla SM, Lopes LC, Vogel N, Chen E, Kirmayr K, De Oliveira K, Olivieri L, Kaushal A, Chaparro LE, Oyberman I, Agarwal A, Couban R, Tsoi L, Lam T, Vandvik PO, Hsu S, Bala MM, Schandelmaier S, Scheidecker A, Ebrahim S, Ashoorion V, Rehman Y, Hong PJ, Ross S, Johnston BC, Kunz R, Sun X, Buckley N, Sessler DI, Guyatt GH.

JAMA. 2018 Dec 18;320(23):2448-2460. doi: 10.1001/jama.2018.18472.


GRADE approach to rate the certainty from a network meta-analysis: Addressing Incoherence.

Brignardello-Petersen R, Mustafa RA, Siemieniuk RAC, Murad MH, Agoritsas T, Izcovich A, Schünemann HJ, Guyatt GH; GRADE Working Group.

J Clin Epidemiol. 2018 Dec 5. pii: S0895-4356(18)30496-7. doi: 10.1016/j.jclinepi.2018.11.025. [Epub ahead of print]


Methods for trustworthy nutritional recommendations NutriRECS (Nutritional Recommendations and accessible Evidence summaries Composed of Systematic reviews): a protocol.

Johnston BC, Alonso-Coello P, Bala MM, Zeraatkar D, Rabassa M, Valli C, Marshall C, El Dib R, Vernooij RWM, Vandvik PO, Guyatt GH.

BMC Med Res Methodol. 2018 Dec 5;18(1):162. doi: 10.1186/s12874-018-0621-8.


Comparative effectiveness and safety of interventions for acute diarrhea and gastroenteritis in children: A systematic review and network meta-analysis.

Florez ID, Veroniki AA, Al Khalifah R, Yepes-Nuñez JJ, Sierra JM, Vernooij RWM, Acosta-Reyes J, Granados CM, Pérez-Gaxiola G, Cuello-Garcia C, Zea AM, Zhang Y, Foroutan N, Guyatt GH, Thabane L.

PLoS One. 2018 Dec 5;13(12):e0207701. doi: 10.1371/journal.pone.0207701. eCollection 2018.


Cause and consequence of loss in vaccine trust.

Dans AL, Dans LF, Silvestre MAA, Halstead SB, Guyatt GH.

Hum Vaccin Immunother. 2018 Dec 4. doi: 10.1080/21645515.2018.1551674. [Epub ahead of print] No abstract available.


Discrepancies between Patient and Surgeon Expectations of Surgery for Sciatica: A Challenge for Informed Decision Making?

Rehman Y, Muzammil S, Wiercioch W, Rehman N, Drew B, Cenic A, Reddy K, Murty N, Kucher E, Dunlop RB, Guyatt GH, Busse JW, Schwartz L, Vanstone M.

Spine (Phila Pa 1976). 2018 Nov 1. doi: 10.1097/BRS.0000000000002914. [Epub ahead of print]


Long-term risks of stress and urgency urinary incontinence after different vaginal delivery modes.

Tähtinen RM, Cartwright R, Vernooij RWM, Rortveit G, Hunskaar S, Guyatt GH, Tikkinen KAO.

Am J Obstet Gynecol. 2019 Feb;220(2):181.e1-181.e8. doi: 10.1016/j.ajog.2018.10.034. Epub 2018 Nov 1.


Oxygen therapy for acutely ill medical patients: a clinical practice guideline.

Siemieniuk RAC, Chu DK, Kim LH, Güell-Rous MR, Alhazzani W, Soccal PM, Karanicolas PJ, Farhoumand PD, Siemieniuk JLK, Satia I, Irusen EM, Refaat MM, Mikita JS, Smith M, Cohen DN, Vandvik PO, Agoritsas T, Lytvyn L, Guyatt GH.

BMJ. 2018 Oct 24;363:k4169. doi: 10.1136/bmj.k4169. No abstract available.


Comparative Effectiveness of Prophylactic Therapies for Necrotizing Enterocolitis in Preterm Infants: Protocol for a Network Meta-analysis of Randomized Trials.

Sadeghirad B, Florez ID, Chang Y, Forutan F, Zeraatkar D, Morgan RL, Shahid S, Bala MM, Beyene J, Offringa M, Adams-Webber T, Sherman PM, El-Gouhary E, Guyatt GH, Johnston BC.

Int J Prev Med. 2018 Sep 17;9:83. doi: 10.4103/ijpvm.IJPVM_328_17. eCollection 2018.


GRADE approach to rate the certainty from a network meta-analysis: avoiding spurious judgments of imprecision in sparse networks.

Brignardello-Petersen R, Murad MH, Walter SD, McLeod S, Carrasco-Labra A, Rochwerg B, Schünemann HJ, Tomlinson G, Guyatt GH; GRADE Working Group.

J Clin Epidemiol. 2019 Jan;105:60-67. doi: 10.1016/j.jclinepi.2018.08.022. Epub 2018 Sep 22.


A Randomized Clinical Trial of n-of-1 Trials-Tribulations of a Trial.

Mirza RD, Guyatt GH.

JAMA Intern Med. 2018 Oct 1;178(10):1378-1379. doi: 10.1001/jamainternmed.2018.3979. No abstract available.


Certainty ranges facilitated explicit and transparent judgments regarding evidence credibility.

Tikkinen KAO, Craigie S, Schünemann HJ, Guyatt GH.

J Clin Epidemiol. 2018 Dec;104:46-51. doi: 10.1016/j.jclinepi.2018.08.014. Epub 2018 Aug 23.


Corticosteroid therapy for sepsis: a clinical practice guideline.

Lamontagne F, Rochwerg B, Lytvyn L, Guyatt GH, Møller MH, Annane D, Kho ME, Adhikari NKJ, Machado F, Vandvik PO, Dodek P, Leboeuf R, Briel M, Hashmi M, Camsooksai J, Shankar-Hari M, Baraki MK, Fugate K, Chua S, Marti C, Cohen D, Botton E, Agoritsas T, Siemieniuk RAC.

BMJ. 2018 Aug 10;362:k3284. doi: 10.1136/bmj.k3284. No abstract available.


Patent foramen ovale closure, antiplatelet therapy or anticoagulation in patients with patent foramen ovale and cryptogenic stroke: a systematic review and network meta-analysis incorporating complementary external evidence.

Mir H, Siemieniuk RAC, Ge LC, Foroutan F, Fralick M, Syed T, Lopes LC, Kuijpers T, Mas JL, Vandvik PO, Agoritsas T, Guyatt GH.

BMJ Open. 2018 Jul 25;8(7):e023761. doi: 10.1136/bmjopen-2018-023761. Erratum in: BMJ Open. 2018 Aug 17;8(8):e023761corr1.


Optimising first- and second-line treatment strategies for untreated major depressive disorder - the SUN☺D study: a pragmatic, multi-centre, assessor-blinded randomised controlled trial.

Kato T, Furukawa TA, Mantani A, Kurata K, Kubouchi H, Hirota S, Sato H, Sugishita K, Chino B, Itoh K, Ikeda Y, Shinagawa Y, Kondo M, Okamoto Y, Fujita H, Suga M, Yasumoto S, Tsujino N, Inoue T, Fujise N, Akechi T, Yamada M, Shimodera S, Watanabe N, Inagaki M, Miki K, Ogawa Y, Takeshima N, Hayasaka Y, Tajika A, Shinohara K, Yonemoto N, Tanaka S, Zhou Q, Guyatt GH; SUN☺D Investigators.

BMC Med. 2018 Jul 11;16(1):103. doi: 10.1186/s12916-018-1096-5.


Academic response to improving value and reducing waste: A comprehensive framework for INcreasing QUality In patient-oriented academic clinical REsearch (INQUIRE).

von Niederhäusern B, Guyatt GH, Briel M, Pauli-Magnus C.

PLoS Med. 2018 Jun 7;15(6):e1002580. doi: 10.1371/journal.pmed.1002580. eCollection 2018 Jun.


Applying GRADE to a network meta-analysis of antidepressants led to more conservative conclusions.

Bonner A, Alexander PE, Brignardello-Petersen R, Furukawa TA, Siemieniuk RA, Zhang Y, Wiercioch W, Florez ID, Fei Y, Agarwal A, Yepes-Nuñez JJ, Beyene J, Schünemann H, Guyatt GH.

J Clin Epidemiol. 2018 Oct;102:87-98. doi: 10.1016/j.jclinepi.2018.05.009. Epub 2018 May 22.


GRADE guidelines: 20. Assessing the certainty of evidence in the importance of outcomes or values and preferences-inconsistency, imprecision, and other domains.

Zhang Y, Coello PA, Guyatt GH, Yepes-Nuñez JJ, Akl EA, Hazlewood G, Pardo-Hernandez H, Etxeandia-Ikobaltzeta I, Qaseem A, Williams JW Jr, Tugwell P, Flottorp S, Chang Y, Zhang Y, Mustafa RA, Rojas MX, Xie F, Schünemann HJ.

J Clin Epidemiol. 2018 May 22. pii: S0895-4356(17)31061-2. doi: 10.1016/j.jclinepi.2018.05.011. [Epub ahead of print]


Corrigendum to "Advances in the GRADE approach to rate the certainty in estimates from a network meta-analysis" [J Clin Epidemiol 2018;93:36-44].

Brignardello-Petersen R, Bonner A, Alexander PE, Siemieniuk RA, Furukawa TA, Rochwerg B, Hazlewood GS, Alhazzani W, Mustafa RA, Murad MH, Puhan MA, Schünemann HJ, Guyatt GH; GRADE Working Group.

J Clin Epidemiol. 2018 Jun;98:162. doi: 10.1016/j.jclinepi.2018.04.013. No abstract available.


Debating the opioid guidelines: context.

Busse JW, Juurlink D, Buckley DN, Guyatt GH.

Can Fam Physician. 2018 May;64(5):330-331. No abstract available.


Debating the opioid guidelines: corrections.

Busse JW, Juurlink D, Buckley DN, Guyatt GH.

Can Fam Physician. 2018 May;64(5):328-330. No abstract available.


Patient Values and Preferences Regarding Opioids for Chronic Noncancer Pain: A Systematic Review.

Goshua A, Craigie S, Guyatt GH, Agarwal A, Li R, Bhullar JS, Scott N, Chahal J, Pavalagantharajah S, Chang Y, Couban R, Busse JW.

Pain Med. 2018 Dec 1;19(12):2469-2480. doi: 10.1093/pm/pnx274.


The authors respond to "The 2017 Canadian opioid guideline: already time for an overhaul".

Busse JW, Juurlink D, Buckley DN, Guyatt GH.

CMAJ. 2018 Mar 12;190(10):E301. doi: 10.1503/cmaj.68675. No abstract available.


GRADE Guidelines: 19. Assessing the certainty of evidence in the importance of outcomes or values and preferences-Risk of bias and indirectness.

Zhang Y, Alonso-Coello P, Guyatt GH, Yepes-Nuñez JJ, Akl EA, Hazlewood G, Pardo-Hernandez H, Etxeandia-Ikobaltzeta I, Qaseem A, Williams JW Jr, Tugwell P, Flottorp S, Chang Y, Zhang Y, Mustafa RA, Rojas MX, Schünemann HJ.

J Clin Epidemiol. 2018 Feb 13. pii: S0895-4356(17)31036-3. doi: 10.1016/j.jclinepi.2018.01.013. [Epub ahead of print]


Antibiotics for uncomplicated skin abscesses: systematic review and network meta-analysis.

Wang W, Chen W, Liu Y, Siemieniuk RAC, Li L, Martínez JPD, Guyatt GH, Sun X.

BMJ Open. 2018 Feb 6;8(2):e020991. doi: 10.1136/bmjopen-2017-020991. Review.


Antibiotics after incision and drainage for uncomplicated skin abscesses: a clinical practice guideline.

Vermandere M, Aertgeerts B, Agoritsas T, Liu C, Burgers J, Merglen A, Okwen PM, Lytvyn L, Chua S, Vandvik PO, Guyatt GH, Beltran-Arroyave C, Lavergne V, Speeckaert R, Steen FE, Arteaga V, Sender R, McLeod S, Sun X, Wang W, Siemieniuk RAC.

BMJ. 2018 Feb 6;360:k243. doi: 10.1136/bmj.k243. No abstract available.


Facilitating healthcare decisions by assessing the certainty in the evidence from preclinical animal studies.

Hooijmans CR, de Vries RBM, Ritskes-Hoitinga M, Rovers MM, Leeflang MM, IntHout J, Wever KE, Hooft L, de Beer H, Kuijpers T, Macleod MR, Sena ES, Ter Riet G, Morgan RL, Thayer KA, Rooney AA, Guyatt GH, Schünemann HJ, Langendam MW; GRADE Working Group.

PLoS One. 2018 Jan 11;13(1):e0187271. doi: 10.1371/journal.pone.0187271. eCollection 2018. Review.


Controversy and debate on dengue vaccine series-paper 3: final response to review of a licensed dengue vaccine: inappropriate subgroup analyses and selective reporting may cause harm in mass vaccination programs.

Dans AL, Dans LF, Lansang MAD, Silvestre MAA, Guyatt GH.

J Clin Epidemiol. 2018 Mar;95:142. doi: 10.1016/j.jclinepi.2017.12.025. Epub 2018 Jan 3. No abstract available.


Pooled analysis of higher versus lower blood pressure targets for vasopressor therapy septic and vasodilatory shock.

Lamontagne F, Day AG, Meade MO, Cook DJ, Guyatt GH, Hylands M, Radermacher P, Chrétien JM, Beaudoin N, Hébert P, D'Aragon F, Meziani F, Asfar P.

Intensive Care Med. 2018 Jan;44(1):12-21. doi: 10.1007/s00134-017-5016-5. Epub 2017 Dec 19.


Controversy and debate on dengue vaccine series-paper 1: review of a licensed dengue vaccine: inappropriate subgroup analyses and selective reporting may cause harm in mass vaccination programs.

Dans AL, Dans LF, Lansang MAD, Silvestre MAA, Guyatt GH.

J Clin Epidemiol. 2018 Mar;95:137-139. doi: 10.1016/j.jclinepi.2017.11.019. Epub 2017 Nov 24.


Predicting Survival in Patients With Heart Failure With an Implantable Cardioverter Defibrillator: The Heart Failure Meta-Score.

Alba AC, Walter SD, Guyatt GH, Levy WC, Fang J, Ross HJ, Lee DS.

J Card Fail. 2018 Nov;24(11):735-745. doi: 10.1016/j.cardfail.2017.11.002. Epub 2017 Nov 22.


On evidence-based medicine - Authors' reply.

Djulbegovic B, Guyatt GH.

Lancet. 2017 Nov 18;390(10109):2245-2246. doi: 10.1016/S0140-6736(17)32854-4. No abstract available.


In localized prostate cancer, radical prostatectomy and observation did not differ for mortality at 13 years.

Tikkinen KAO, Guyatt GH.

Ann Intern Med. 2017 Nov 21;167(10):JC53. doi: 10.7326/ACPJC-2017-167-10-053. No abstract available.


UpToDate adherence to GRADE criteria for strong recommendations: an analytical survey.

Agoritsas T, Merglen A, Heen AF, Kristiansen A, Neumann I, Brito JP, Brignardello-Petersen R, Alexander PE, Rind DM, Vandvik PO, Guyatt GH.

BMJ Open. 2017 Nov 16;7(11):e018593. doi: 10.1136/bmjopen-2017-018593.


Association between statistical significance and time to publication among systematic reviews: a study protocol for a meta-epidemiological investigation.

Tsujimoto Y, Tsutsumi Y, Kataoka Y, Tsujimoto H, Yamamoto Y, Papola D, Guyatt GH, Fukuhara S, Furukawa TA.

BMJ Open. 2017 Oct 22;7(10):e018856. doi: 10.1136/bmjopen-2017-018856. Review.


Evidence-based guidelines for supportive care of patients with Ebola virus disease.

Lamontagne F, Fowler RA, Adhikari NK, Murthy S, Brett-Major DM, Jacobs M, Uyeki TM, Vallenas C, Norris SL, Fischer WA 2nd, Fletcher TE, Levine AC, Reed P, Bausch DG, Gove S, Hall A, Shepherd S, Siemieniuk RA, Lamah MC, Kamara R, Nakyeyune P, Soka MJ, Edwin A, Hazzan AA, Jacob ST, Elkarsany MM, Adachi T, Benhadj L, Clément C, Crozier I, Garcia A, Hoffman SJ, Guyatt GH.

Lancet. 2018 Feb 17;391(10121):700-708. doi: 10.1016/S0140-6736(17)31795-6. Epub 2017 Oct 17.


Advances in the GRADE approach to rate the certainty in estimates from a network meta-analysis.

Brignardello-Petersen R, Bonner A, Alexander PE, Siemieniuk RA, Furukawa TA, Rochwerg B, Hazlewood GS, Alhazzani W, Mustafa RA, Murad MH, Puhan MA, Schünemann HJ, Guyatt GH; GRADE Working Group.

J Clin Epidemiol. 2018 Jan;93:36-44. doi: 10.1016/j.jclinepi.2017.10.005. Epub 2017 Oct 17. Erratum in: J Clin Epidemiol. 2018 Jun;98 :162.


Decision-making frameworks and considerations for informing coverage decisions for healthcare interventions: a critical interpretive synthesis.

Morgan RL, Kelley L, Guyatt GH, Johnson A, Lavis JN.

J Clin Epidemiol. 2018 Feb;94:143-150. doi: 10.1016/j.jclinepi.2017.09.023. Epub 2017 Oct 6.


The authors respond to "Inconsistencies in the 2017 Canadian Guideline for Opioids for Chronic Noncancer Pain".

Busse JW, Juurlink DN, Buckley DN, Guyatt GH.

CMAJ. 2017 Oct 2;189(39):E1234-E1235. doi: 10.1503/cmaj.733313. No abstract available.


Arthroscopic surgery for knee pain.

Järvinen TLN, Guyatt GH.

Br J Sports Med. 2017 Oct;51(20):1502. doi: 10.1136/bjsports-2017-i3740rep. No abstract available.


Canada-DONATE study protocol: a prospective national observational study of the medical management of deceased organ donors.

D'Aragon F, Dhanani S, Lamontagne F, Cook DJ, Burns K, Akhtar A, Chassé M, Frenette AJ, Keenan S, Lize JF, Kutsogiannis DJ, Kramer A, Hand LE, Arseneau E, Masse MH, Ribic C, Ball I, Baker A, Boyd G, Rochwerg B, Healey A, Hanna S, Guyatt GH, Meade MO; Canadian Critical Care Trials Group and the Canadian National Transplant Research Program.

BMJ Open. 2017 Sep 28;7(9):e018858. doi: 10.1136/bmjopen-2017-018858.


Presentation approaches for enhancing interpretability of patient-reported outcomes (PROs) in meta-analysis: a protocol for a systematic survey of Cochrane reviews.

Devji T, Johnston BC, Patrick DL, Bhandari M, Thabane L, Guyatt GH.

BMJ Open. 2017 Sep 27;7(9):e017138. doi: 10.1136/bmjopen-2017-017138.


Bleeding impacting mortality after noncardiac surgery: a protocol to establish diagnostic criteria, estimate prognostic importance, and develop and validate a prediction guide in an international prospective cohort study.

Roshanov PS, Eikelboom JW, Crowther M, Tandon V, Borges FK, Kearon C, Lamy A, Whitlock R, Biccard BM, Szczeklik W, Guyatt GH, Panju M, Spence J, Garg AX, McGillion M, VanHelder T, Kavsak PA, de Beer J, Winemaker M, Sessler DI, Le Manach Y, Sheth T, Pinthus JH, Thabane L, Simunovic MRI, Mizera R, Ribas S, Devereaux PJ; Vascular Events In Noncardiac Surgery Patients Cohort Evaluation (VISION) Investigators.

CMAJ Open. 2017 Aug 4;5(3):E594-E603. doi: 10.9778/cmajo.20160106.


Corticosteroids for treatment of sore throat: systematic review and meta-analysis of randomised trials.

Sadeghirad B, Siemieniuk RAC, Brignardello-Petersen R, Papola D, Lytvyn L, Vandvik PO, Merglen A, Guyatt GH, Agoritsas T.

BMJ. 2017 Sep 20;358:j3887. doi: 10.1136/bmj.j3887. Review.


[GRADE Evidence to Decision (EtD) frameworks: a systematic and transparent approach to making well informed healthcare choices. 2: Clinical practice guidelines].

Alonso-Coello P, Oxman AD, Moberg J, Brignardello-Petersen R, Akl EA, Davoli M, Treweek S, Mustafa RA, Vandvik PO, Meerpohl J, Guyatt GH, Schünemann HJ; el GRADE Working Group.

Gac Sanit. 2018 Mar - Apr;32(2):167.e1-167.e10. doi: 10.1016/j.gaceta.2017.03.008. Epub 2017 Sep 13. Spanish.


Antiretroviral therapy for pregnant women living with HIV or hepatitis B: a systematic review and meta-analysis.

Siemieniuk RA, Foroutan F, Mirza R, Mah Ming J, Alexander PE, Agarwal A, Lesi O, Merglen A, Chang Y, Zhang Y, Mir H, Hepworth E, Lee Y, Zeraatkar D, Guyatt GH.

BMJ Open. 2017 Sep 11;7(9):e019022. doi: 10.1136/bmjopen-2017-019022. Review.

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