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Optimising first- and second-line treatment strategies for untreated major depressive disorder - the SUN☺D study: a pragmatic, multi-centre, assessor-blinded randomised controlled trial.

Kato T, Furukawa TA, Mantani A, Kurata K, Kubouchi H, Hirota S, Sato H, Sugishita K, Chino B, Itoh K, Ikeda Y, Shinagawa Y, Kondo M, Okamoto Y, Fujita H, Suga M, Yasumoto S, Tsujino N, Inoue T, Fujise N, Akechi T, Yamada M, Shimodera S, Watanabe N, Inagaki M, Miki K, Ogawa Y, Takeshima N, Hayasaka Y, Tajika A, Shinohara K, Yonemoto N, Tanaka S, Zhou Q, Guyatt GH; SUN☺D Investigators.

BMC Med. 2018 Jul 11;16(1):103. doi: 10.1186/s12916-018-1096-5.


Academic response to improving value and reducing waste: A comprehensive framework for INcreasing QUality In patient-oriented academic clinical REsearch (INQUIRE).

von Niederhäusern B, Guyatt GH, Briel M, Pauli-Magnus C.

PLoS Med. 2018 Jun 7;15(6):e1002580. doi: 10.1371/journal.pmed.1002580. eCollection 2018 Jun.


Applying GRADE to a network meta-analysis of antidepressants led to more conservative conclusions.

Bonner A, Alexander PE, Brignardello-Petersen R, Furukawa TA, Siemieniuk RA, Zhang Y, Wiercioch W, Florez ID, Fei Y, Agarwal A, Yepes-Nuñez JJ, Beyene J, Schünemann H, Guyatt GH.

J Clin Epidemiol. 2018 May 22. pii: S0895-4356(17)31085-5. doi: 10.1016/j.jclinepi.2018.05.009. [Epub ahead of print]


Corrigendum to "Advances in the GRADE approach to rate the certainty in estimates from a network meta-analysis" [J Clin Epidemiol 2018;93:36-44].

Brignardello-Petersen R, Bonner A, Alexander PE, Siemieniuk RA, Furukawa TA, Rochwerg B, Hazlewood GS, Alhazzani W, Mustafa RA, Murad MH, Puhan MA, Schünemann HJ, Guyatt GH; GRADE Working Group.

J Clin Epidemiol. 2018 Jun;98:162. doi: 10.1016/j.jclinepi.2018.04.013. No abstract available.


Debating the opioid guidelines: context.

Busse JW, Juurlink D, Buckley DN, Guyatt GH.

Can Fam Physician. 2018 May;64(5):330-331. No abstract available.


Debating the opioid guidelines: corrections.

Busse JW, Juurlink D, Buckley DN, Guyatt GH.

Can Fam Physician. 2018 May;64(5):328-330. No abstract available.


Patient Values and Preferences Regarding Opioids for Chronic Noncancer Pain: A Systematic Review.

Goshua A, Craigie S, Guyatt GH, Agarwal A, Li R, Bhullar JS, Scott N, Chahal J, Pavalagantharajah S, Chang Y, Couban R, Busse JW.

Pain Med. 2017 Nov 22. doi: 10.1093/pm/pnx274. [Epub ahead of print]


The authors respond to "The 2017 Canadian opioid guideline: already time for an overhaul".

Busse JW, Juurlink D, Buckley DN, Guyatt GH.

CMAJ. 2018 Mar 12;190(10):E301. doi: 10.1503/cmaj.68675. No abstract available.


GRADE Guidelines: 19. Assessing the certainty of evidence in the importance of outcomes or values and preferences-Risk of bias and indirectness.

Zhang Y, Alonso-Coello P, Guyatt GH, Yepes-Nuñez JJ, Akl EA, Hazlewood G, Pardo-Hernandez H, Etxeandia-Ikobaltzeta I, Qaseem A, Williams JW Jr, Tugwell P, Flottorp S, Chang Y, Zhang Y, Mustafa RA, Rojas MX, Schünemann HJ.

J Clin Epidemiol. 2018 Feb 13. pii: S0895-4356(17)31036-3. doi: 10.1016/j.jclinepi.2018.01.013. [Epub ahead of print]


Antibiotics for uncomplicated skin abscesses: systematic review and network meta-analysis.

Wang W, Chen W, Liu Y, Siemieniuk RAC, Li L, Martínez JPD, Guyatt GH, Sun X.

BMJ Open. 2018 Feb 6;8(2):e020991. doi: 10.1136/bmjopen-2017-020991.


Antibiotics after incision and drainage for uncomplicated skin abscesses: a clinical practice guideline.

Vermandere M, Aertgeerts B, Agoritsas T, Liu C, Burgers J, Merglen A, Okwen PM, Lytvyn L, Chua S, Vandvik PO, Guyatt GH, Beltran-Arroyave C, Lavergne V, Speeckaert R, Steen FE, Arteaga V, Sender R, McLeod S, Sun X, Wang W, Siemieniuk RAC.

BMJ. 2018 Feb 6;360:k243. doi: 10.1136/bmj.k243. No abstract available.


Facilitating healthcare decisions by assessing the certainty in the evidence from preclinical animal studies.

Hooijmans CR, de Vries RBM, Ritskes-Hoitinga M, Rovers MM, Leeflang MM, IntHout J, Wever KE, Hooft L, de Beer H, Kuijpers T, Macleod MR, Sena ES, Ter Riet G, Morgan RL, Thayer KA, Rooney AA, Guyatt GH, Schünemann HJ, Langendam MW; GRADE Working Group.

PLoS One. 2018 Jan 11;13(1):e0187271. doi: 10.1371/journal.pone.0187271. eCollection 2018. Review.


Controversy and debate on dengue vaccine series-paper 3: final response to review of a licensed dengue vaccine: inappropriate subgroup analyses and selective reporting may cause harm in mass vaccination programs.

Dans AL, Dans LF, Lansang MAD, Silvestre MAA, Guyatt GH.

J Clin Epidemiol. 2018 Mar;95:142. doi: 10.1016/j.jclinepi.2017.12.025. Epub 2018 Jan 3. No abstract available.


Pooled analysis of higher versus lower blood pressure targets for vasopressor therapy septic and vasodilatory shock.

Lamontagne F, Day AG, Meade MO, Cook DJ, Guyatt GH, Hylands M, Radermacher P, Chrétien JM, Beaudoin N, Hébert P, D'Aragon F, Meziani F, Asfar P.

Intensive Care Med. 2018 Jan;44(1):12-21. doi: 10.1007/s00134-017-5016-5. Epub 2017 Dec 19. Review.


Controversy and debate on dengue vaccine series-paper 1: review of a licensed dengue vaccine: inappropriate subgroup analyses and selective reporting may cause harm in mass vaccination programs.

Dans AL, Dans LF, Lansang MAD, Silvestre MAA, Guyatt GH.

J Clin Epidemiol. 2018 Mar;95:137-139. doi: 10.1016/j.jclinepi.2017.11.019. Epub 2017 Nov 24.


Predicting Survival in Heart Failure Patients With Implantable Cardioverter-Defibrillators: The Heart Failure Meta-score.

Alba AC, Walter SD, Guyatt GH, Levy WC, Fang J, Ross HJ, Lee DS.

J Card Fail. 2017 Nov 22. pii: S1071-9164(17)31276-9. doi: 10.1016/j.cardfail.2017.11.002. [Epub ahead of print]


On evidence-based medicine - Authors' reply.

Djulbegovic B, Guyatt GH.

Lancet. 2017 Nov 18;390(10109):2245-2246. doi: 10.1016/S0140-6736(17)32854-4. No abstract available.


In localized prostate cancer, radical prostatectomy and observation did not differ for mortality at 13 years.

Tikkinen KAO, Guyatt GH.

Ann Intern Med. 2017 Nov 21;167(10):JC53. doi: 10.7326/ACPJC-2017-167-10-053. No abstract available.


UpToDate adherence to GRADE criteria for strong recommendations: an analytical survey.

Agoritsas T, Merglen A, Heen AF, Kristiansen A, Neumann I, Brito JP, Brignardello-Petersen R, Alexander PE, Rind DM, Vandvik PO, Guyatt GH.

BMJ Open. 2017 Nov 16;7(11):e018593. doi: 10.1136/bmjopen-2017-018593.


Low-intensity pulsed ultrasound for treatment of tibial fractures: an economic evaluation of the TRUST study.

Tarride JE, Hopkins RB, Blackhouse G, Burke N, Bhandari M, Johal H, Guyatt GH, Busse JW.

Bone Joint J. 2017 Nov;99-B(11):1526-1532. doi: 10.1302/0301-620X.99B11.BJJ-2017-0737.


Association between statistical significance and time to publication among systematic reviews: a study protocol for a meta-epidemiological investigation.

Tsujimoto Y, Tsutsumi Y, Kataoka Y, Tsujimoto H, Yamamoto Y, Papola D, Guyatt GH, Fukuhara S, Furukawa TA.

BMJ Open. 2017 Oct 22;7(10):e018856. doi: 10.1136/bmjopen-2017-018856. Review.


Evidence-based guidelines for supportive care of patients with Ebola virus disease.

Lamontagne F, Fowler RA, Adhikari NK, Murthy S, Brett-Major DM, Jacobs M, Uyeki TM, Vallenas C, Norris SL, Fischer WA 2nd, Fletcher TE, Levine AC, Reed P, Bausch DG, Gove S, Hall A, Shepherd S, Siemieniuk RA, Lamah MC, Kamara R, Nakyeyune P, Soka MJ, Edwin A, Hazzan AA, Jacob ST, Elkarsany MM, Adachi T, Benhadj L, Clément C, Crozier I, Garcia A, Hoffman SJ, Guyatt GH.

Lancet. 2018 Feb 17;391(10121):700-708. doi: 10.1016/S0140-6736(17)31795-6. Epub 2017 Oct 17.


Advances in the GRADE approach to rate the certainty in estimates from a network meta-analysis.

Brignardello-Petersen R, Bonner A, Alexander PE, Siemieniuk RA, Furukawa TA, Rochwerg B, Hazlewood GS, Alhazzani W, Mustafa RA, Murad MH, Puhan MA, Schünemann HJ, Guyatt GH; GRADE Working Group.

J Clin Epidemiol. 2018 Jan;93:36-44. doi: 10.1016/j.jclinepi.2017.10.005. Epub 2017 Oct 17. Erratum in: J Clin Epidemiol. 2018 Jun;98 :162.


Decision-making frameworks and considerations for informing coverage decisions for healthcare interventions: a critical interpretive synthesis.

Morgan RL, Kelley L, Guyatt GH, Johnson A, Lavis JN.

J Clin Epidemiol. 2018 Feb;94:143-150. doi: 10.1016/j.jclinepi.2017.09.023. Epub 2017 Oct 6.


The authors respond to "Inconsistencies in the 2017 Canadian Guideline for Opioids for Chronic Noncancer Pain".

Busse JW, Juurlink DN, Buckley DN, Guyatt GH.

CMAJ. 2017 Oct 2;189(39):E1234-E1235. doi: 10.1503/cmaj.733313. No abstract available.


Arthroscopic surgery for knee pain.

Järvinen TLN, Guyatt GH.

Br J Sports Med. 2017 Oct;51(20):1502. doi: 10.1136/bjsports-2017-i3740rep. No abstract available.


Canada-DONATE study protocol: a prospective national observational study of the medical management of deceased organ donors.

D'Aragon F, Dhanani S, Lamontagne F, Cook DJ, Burns K, Akhtar A, Chassé M, Frenette AJ, Keenan S, Lize JF, Kutsogiannis DJ, Kramer A, Hand LE, Arseneau E, Masse MH, Ribic C, Ball I, Baker A, Boyd G, Rochwerg B, Healey A, Hanna S, Guyatt GH, Meade MO; Canadian Critical Care Trials Group and the Canadian National Transplant Research Program.

BMJ Open. 2017 Sep 28;7(9):e018858. doi: 10.1136/bmjopen-2017-018858.


Presentation approaches for enhancing interpretability of patient-reported outcomes (PROs) in meta-analysis: a protocol for a systematic survey of Cochrane reviews.

Devji T, Johnston BC, Patrick DL, Bhandari M, Thabane L, Guyatt GH.

BMJ Open. 2017 Sep 27;7(9):e017138. doi: 10.1136/bmjopen-2017-017138. Review.


Bleeding impacting mortality after noncardiac surgery: a protocol to establish diagnostic criteria, estimate prognostic importance, and develop and validate a prediction guide in an international prospective cohort study.

Roshanov PS, Eikelboom JW, Crowther M, Tandon V, Borges FK, Kearon C, Lamy A, Whitlock R, Biccard BM, Szczeklik W, Guyatt GH, Panju M, Spence J, Garg AX, McGillion M, VanHelder T, Kavsak PA, de Beer J, Winemaker M, Sessler DI, Le Manach Y, Sheth T, Pinthus JH, Thabane L, Simunovic MRI, Mizera R, Ribas S, Devereaux PJ; Vascular Events In Noncardiac Surgery Patients Cohort Evaluation (VISION) Investigators.

CMAJ Open. 2017 Aug 4;5(3):E594-E603. doi: 10.9778/cmajo.20160106.


Corticosteroids for treatment of sore throat: systematic review and meta-analysis of randomised trials.

Sadeghirad B, Siemieniuk RAC, Brignardello-Petersen R, Papola D, Lytvyn L, Vandvik PO, Merglen A, Guyatt GH, Agoritsas T.

BMJ. 2017 Sep 20;358:j3887. doi: 10.1136/bmj.j3887. Review.


[GRADE Evidence to Decision (EtD) frameworks: a systematic and transparent approach to making well informed healthcare choices. 2: Clinical practice guidelines].

Alonso-Coello P, Oxman AD, Moberg J, Brignardello-Petersen R, Akl EA, Davoli M, Treweek S, Mustafa RA, Vandvik PO, Meerpohl J, Guyatt GH, Schünemann HJ; el GRADE Working Group.

Gac Sanit. 2018 Mar - Apr;32(2):167.e1-167.e10. doi: 10.1016/j.gaceta.2017.03.008. Epub 2017 Sep 13. Spanish.


Antiretroviral therapy for pregnant women living with HIV or hepatitis B: a systematic review and meta-analysis.

Siemieniuk RA, Foroutan F, Mirza R, Mah Ming J, Alexander PE, Agarwal A, Lesi O, Merglen A, Chang Y, Zhang Y, Mir H, Hepworth E, Lee Y, Zeraatkar D, Guyatt GH.

BMJ Open. 2017 Sep 11;7(9):e019022. doi: 10.1136/bmjopen-2017-019022. Review.


Antiretroviral therapy in pregnant women living with HIV: a clinical practice guideline.

Siemieniuk RAC, Lytvyn L, Mah Ming J, Mullen RM, Anam F, Otieno T, Guyatt GH, Taylor GP, Beltrán-Arroyave C, Okwen PM, Nduati R, Kinuthia J, Luma HN, Kirpalani H, Merglen A, Lesi OA, Vandvik PO, Agoritsas T, Bewley S.

BMJ. 2017 Sep 11;358:j3961. doi: 10.1136/bmj.j3961. No abstract available.


[GRADE Evidence to Decision (EtD) frameworks: a systematic and transparent approach to making well informed healthcare choices. 1: Introduction].

Alonso-Coello P, Schünemann HJ, Moberg J, Brignardello-Petersen R, Akl EA, Davoli M, Treweek S, Mustafa RA, Rada G, Rosenbaum S, Morelli A, Guyatt GH, Oxman AD; el GRADE Working Group.

Gac Sanit. 2018 Mar - Apr;32(2):166.e1-166.e10. doi: 10.1016/j.gaceta.2017.02.010. Epub 2017 Aug 17. Spanish.


Factors Associated With Health-Related Quality of Life in Patients With Open Fractures.

Sprague S, Petrisor BA, Jeray KJ, McKay P, Scott T, Heels-Ansdell D, Schemitsch EH, Liew S, Guyatt GH, Walter SD, Bhandari M.

J Orthop Trauma. 2018 Jan;32(1):e5-e11. doi: 10.1097/BOT.0000000000000993.


Towards the development of a comprehensive framework: Qualitative systematic survey of definitions of clinical research quality.

von Niederhäusern B, Schandelmaier S, Mi Bonde M, Brunner N, Hemkens LG, Rutquist M, Bhatnagar N, Guyatt GH, Pauli-Magnus C, Briel M.

PLoS One. 2017 Jul 17;12(7):e0180635. doi: 10.1371/journal.pone.0180635. eCollection 2017.


Perspective: Improving Nutritional Guidelines for Sustainable Health Policies: Current Status and Perspectives.

Magni P, Bier DM, Pecorelli S, Agostoni C, Astrup A, Brighenti F, Cook R, Folco E, Fontana L, Gibson RA, Guerra R, Guyatt GH, Ioannidis JP, Jackson AS, Klurfeld DM, Makrides M, Mathioudakis B, Monaco A, Patel CJ, Racagni G, Schünemann HJ, Shamir R, Zmora N, Peracino A.

Adv Nutr. 2017 Jul 14;8(4):532-545. doi: 10.3945/an.116.014738. Print 2017 Jul.


Structural valve deterioration after transcatheter aortic valve implantation.

Foroutan F, Guyatt GH, Otto CM, Siemieniuk RA, Schandelmaier S, Agoritsas T, Vandvik PO, Bhagra S, Bagur R.

Heart. 2017 Dec;103(23):1899-1905. doi: 10.1136/heartjnl-2017-311329. Epub 2017 Jul 6. Review.


Surgery: Falling out of love with knee arthroscopy.

Järvinen TLN, Guyatt GH.

Nat Rev Rheumatol. 2017 Sep;13(9):515-516. doi: 10.1038/nrrheum.2017.106. Epub 2017 Jul 6. No abstract available.


In severe aortic stenosis with intermediate surgical risk, TAVR was noninferior to SAVR for death or disabling stroke.

Spencer FA, Guyatt GH.

Ann Intern Med. 2017 Jun 20;166(12):JC68. doi: 10.7326/ACPJC-2017-166-12-068. No abstract available.


Incretin based treatments and mortality in patients with type 2 diabetes: systematic review and meta-analysis.

Liu J, Li L, Deng K, Xu C, Busse JW, Vandvik PO, Li S, Guyatt GH, Sun X.

BMJ. 2017 Jun 8;357:j2499. doi: 10.1136/bmj.j2499. Review.


Adjustment Strategies in Studies of Therapy-Reply.

Agoritsas T, Merglen A, Guyatt GH.

JAMA. 2017 Jun 6;317(21):2238-2239. doi: 10.1001/jama.2017.4887. No abstract available.


A systematic survey on reporting and methods for handling missing participant data for continuous outcomes in randomized controlled trials.

Zhang Y, Flórez ID, Colunga Lozano LE, Aloweni FAB, Kennedy SA, Li A, Craigie S, Zhang S, Agarwal A, Lopes LC, Devji T, Wiercioch W, Riva JJ, Wang M, Jin X, Fei Y, Alexander P, Morgano GP, Zhang Y, Carrasco-Labra A, Kahale LA, Akl EA, Schünemann HJ, Thabane L, Guyatt GH.

J Clin Epidemiol. 2017 Aug;88:57-66. doi: 10.1016/j.jclinepi.2017.05.017. Epub 2017 Jun 3. Review.


A systematic survey of the methods literature on the reporting quality and optimal methods of handling participants with missing outcome data for continuous outcomes in randomized controlled trials.

Zhang Y, Alyass A, Vanniyasingam T, Sadeghirad B, Flórez ID, Pichika SC, Kennedy SA, Abdulkarimova U, Zhang Y, Iljon T, Morgano GP, Colunga Lozano LE, Aloweni FAB, Lopes LC, Yepes-Nuñez JJ, Fei Y, Wang L, Kahale LA, Meyre D, Akl EA, Thabane L, Guyatt GH.

J Clin Epidemiol. 2017 Aug;88:67-80. doi: 10.1016/j.jclinepi.2017.05.016. Epub 2017 Jun 1. Review.


GRADE guidelines 17: assessing the risk of bias associated with missing participant outcome data in a body of evidence.

Guyatt GH, Ebrahim S, Alonso-Coello P, Johnston BC, Mathioudakis AG, Briel M, Mustafa RA, Sun X, Walter SD, Heels-Ansdell D, Neumann I, Kahale LA, Iorio A, Meerpohl J, Schünemann HJ, Akl EA.

J Clin Epidemiol. 2017 Jul;87:14-22. doi: 10.1016/j.jclinepi.2017.05.005. Epub 2017 May 18.


The next frontier in critical care guidelines: rapid and trustworthy recommendations.

Siemieniuk RAC, Guyatt GH.

Can J Anaesth. 2017 Jul;64(7):689-692. doi: 10.1007/s12630-017-0876-2. Epub 2017 May 11. No abstract available.


Knee arthroscopy versus conservative management in patients with degenerative knee disease: a systematic review.

Brignardello-Petersen R, Guyatt GH, Buchbinder R, Poolman RW, Schandelmaier S, Chang Y, Sadeghirad B, Evaniew N, Vandvik PO.

BMJ Open. 2017 May 11;7(5):e016114. doi: 10.1136/bmjopen-2017-016114. Review.


Application of minimal important differences in degenerative knee disease outcomes: a systematic review and case study to inform BMJ Rapid Recommendations.

Devji T, Guyatt GH, Lytvyn L, Brignardello-Petersen R, Foroutan F, Sadeghirad B, Buchbinder R, Poolman RW, Harris IA, Carrasco-Labra A, Siemieniuk RAC, Vandvik PO.

BMJ Open. 2017 May 11;7(5):e015587. doi: 10.1136/bmjopen-2016-015587. Review.


Guideline for opioid therapy and chronic noncancer pain.

Busse JW, Craigie S, Juurlink DN, Buckley DN, Wang L, Couban RJ, Agoritsas T, Akl EA, Carrasco-Labra A, Cooper L, Cull C, da Costa BR, Frank JW, Grant G, Iorio A, Persaud N, Stern S, Tugwell P, Vandvik PO, Guyatt GH.

CMAJ. 2017 May 8;189(18):E659-E666. doi: 10.1503/cmaj.170363. No abstract available.


Association of Postoperative High-Sensitivity Troponin Levels With Myocardial Injury and 30-Day Mortality Among Patients Undergoing Noncardiac Surgery.

Writing Committee for the VISION Study Investigators, Devereaux PJ, Biccard BM, Sigamani A, Xavier D, Chan MTV, Srinathan SK, Walsh M, Abraham V, Pearse R, Wang CY, Sessler DI, Kurz A, Szczeklik W, Berwanger O, Villar JC, Malaga G, Garg AX, Chow CK, Ackland G, Patel A, Borges FK, Belley-Cote EP, Duceppe E, Spence J, Tandon V, Williams C, Sapsford RJ, Polanczyk CA, Tiboni M, Alonso-Coello P, Faruqui A, Heels-Ansdell D, Lamy A, Whitlock R, LeManach Y, Roshanov PS, McGillion M, Kavsak P, McQueen MJ, Thabane L, Rodseth RN, Buse GAL, Bhandari M, Garutti I, Jacka MJ, Schünemann HJ, Cortes OL, Coriat P, Dvirnik N, Botto F, Pettit S, Jaffe AS, Guyatt GH.

JAMA. 2017 Apr 25;317(16):1642-1651. doi: 10.1001/jama.2017.4360.


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