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Boutiques: a flexible framework to integrate command-line applications in computing platforms.

Glatard T, Kiar G, Aumentado-Armstrong T, Beck N, Bellec P, Bernard R, Bonnet A, Brown ST, Camarasu-Pop S, Cervenansky F, Das S, Ferreira da Silva R, Flandin G, Girard P, Gorgolewski KJ, Guttmann CRG, Hayot-Sasson V, Quirion PO, Rioux P, Rousseau MÉ, Evans AC.

Gigascience. 2018 May 1;7(5). doi: 10.1093/gigascience/giy016.


Diagnostic value of 3DFLAIR in clinical practice for the detection of infratentorial lesions in multiple sclerosis in regard to dual echo T2 sequences.

Hannoun S, Heidelberg D, Hourani R, Nguyen TTT, Brisset JC, Grand S, Kremer S, Bonneville F, Guttmann CRG, Dousset V, Cotton F; Imaging Working Group of the Observatoire Français de la Sclérose en Plaques.

Eur J Radiol. 2018 May;102:146-151. doi: 10.1016/j.ejrad.2018.03.017. Epub 2018 Mar 15.


Longitudinal microstructural changes of cerebral white matter and their association with mobility performance in older persons.

Moscufo N, Wakefield DB, Meier DS, Cavallari M, Guttmann CRG, White WB, Wolfson L.

PLoS One. 2018 Mar 19;13(3):e0194051. doi: 10.1371/journal.pone.0194051. eCollection 2018.


Dual-Sensitivity Multiple Sclerosis Lesion and CSF Segmentation for Multichannel 3T Brain MRI.

Meier DS, Guttmann CRG, Tummala S, Moscufo N, Cavallari M, Tauhid S, Bakshi R, Weiner HL.

J Neuroimaging. 2018 Jan;28(1):36-47. doi: 10.1111/jon.12491. Epub 2017 Dec 13.


Evaluating the Association between Enlarged Perivascular Spaces and Disease Worsening in Multiple Sclerosis.

Cavallari M, Egorova S, Healy BC, Palotai M, Prieto JC, Polgar-Turcsanyi M, Tauhid S, Anderson M, Glanz B, Chitnis T, Guttmann CRG.

J Neuroimaging. 2018 May;28(3):273-277. doi: 10.1111/jon.12490. Epub 2017 Dec 11.


The effect of alcohol and red wine consumption on clinical and MRI outcomes in multiple sclerosis.

Diaz-Cruz C, Chua AS, Malik MT, Kaplan T, Glanz BI, Egorova S, Guttmann CRG, Bakshi R, Weiner HL, Healy BC, Chitnis T.

Mult Scler Relat Disord. 2017 Oct;17:47-53. doi: 10.1016/j.msard.2017.06.011. Epub 2017 Jun 27.


State of the Art and Promise of Structural Neuroimaging in Postoperative Delirium and Postoperative Cognitive Decline.

Cavallari M, Guttmann CRG, Inouye SK, Alsop DC.

Am J Geriatr Psychiatry. 2017 Oct;25(10):1062-1063. doi: 10.1016/j.jagp.2017.07.009. Epub 2017 Jul 14. No abstract available.


Longitudinal diffusion changes following postoperative delirium in older people without dementia.

Cavallari M, Dai W, Guttmann CRG, Meier DS, Ngo LH, Hshieh TT, Fong TG, Schmitt E, Press DZ, Travison TG, Marcantonio ER, Jones RN, Inouye SK, Alsop DC; SAGES Study Group.

Neurology. 2017 Sep 5;89(10):1020-1027. doi: 10.1212/WNL.0000000000004329. Epub 2017 Aug 4.


Changes to the septo-fornical area might play a role in the pathogenesis of anxiety in multiple sclerosis.

Palotai M, Mike A, Cavallari M, Strammer E, Orsi G, Healy BC, Schregel K, Illes Z, Guttmann CR.

Mult Scler. 2018 Jul;24(8):1105-1114. doi: 10.1177/1352458517711273. Epub 2017 May 26.


Exploration of machine learning techniques in predicting multiple sclerosis disease course.

Zhao Y, Healy BC, Rotstein D, Guttmann CR, Bakshi R, Weiner HL, Brodley CE, Chitnis T.

PLoS One. 2017 Apr 5;12(4):e0174866. doi: 10.1371/journal.pone.0174866. eCollection 2017.


Characterizing Clinical and MRI Dissociation in Patients with Multiple Sclerosis.

Healy BC, Buckle GJ, Ali EN, Egorova S, Khalid F, Tauhid S, Glanz BI, Chitnis T, Guttmann CRG, Weiner HL, Bakshi R.

J Neuroimaging. 2017 Sep;27(5):481-485. doi: 10.1111/jon.12433. Epub 2017 Mar 6.


The central vein sign and its clinical evaluation for the diagnosis of multiple sclerosis: a consensus statement from the North American Imaging in Multiple Sclerosis Cooperative.

Sati P, Oh J, Constable RT, Evangelou N, Guttmann CR, Henry RG, Klawiter EC, Mainero C, Massacesi L, McFarland H, Nelson F, Ontaneda D, Rauscher A, Rooney WD, Samaraweera AP, Shinohara RT, Sobel RA, Solomon AJ, Treaba CA, Wuerfel J, Zivadinov R, Sicotte NL, Pelletier D, Reich DS; NAIMS Cooperative.

Nat Rev Neurol. 2016 Dec;12(12):714-722. doi: 10.1038/nrneurol.2016.166. Epub 2016 Nov 11. Review.


Posterior lobules of the cerebellum and information processing speed at various stages of multiple sclerosis.

Moroso A, Ruet A, Lamargue-Hamel D, Munsch F, Deloire M, Coupé P, Ouallet JC, Planche V, Moscufo N, Meier DS, Tourdias T, Guttmann CR, Dousset V, Brochet B.

J Neurol Neurosurg Psychiatry. 2017 Feb;88(2):146-151. doi: 10.1136/jnnp-2016-313867. Epub 2016 Oct 27.


Hippocampal microstructural damage correlates with memory impairment in clinically isolated syndrome suggestive of multiple sclerosis.

Planche V, Ruet A, Coupé P, Lamargue-Hamel D, Deloire M, Pereira B, Manjon JV, Munsch F, Moscufo N, Meier DS, Guttmann CR, Dousset V, Brochet B, Tourdias T.

Mult Scler. 2017 Aug;23(9):1214-1224. doi: 10.1177/1352458516675750. Epub 2016 Oct 25.


Cerebral blood flow MRI in the nondemented elderly is not predictive of post-operative delirium but is correlated with cognitive performance.

Hshieh TT, Dai W, Cavallari M, Guttmann CR, Meier DS, Schmitt EM, Dickerson BC, Press DZ, Marcantonio ER, Jones RN, Gou YR, Travison TG, Fong TG, Ngo L, Inouye SK, Alsop DC; SAGES Study Group.

J Cereb Blood Flow Metab. 2017 Apr;37(4):1386-1397. doi: 10.1177/0271678X16656014. Epub 2016 Jan 1.


Reply: Neural substrates of vulnerability to post-surgical delirium with prospective diagnosis.

Cavallari M, Guttmann CR, Jones RN, Inouye SK, Alsop DC; SAGES Study Group.

Brain. 2016 Oct;139(Pt 10):e55. Epub 2016 Jun 24. No abstract available.


A Sensitive and Automatic White Matter Fiber Tracts Model for Longitudinal Analysis of Diffusion Tensor Images in Multiple Sclerosis.

Stamile C, Kocevar G, Cotton F, Durand-Dubief F, Hannoun S, Frindel C, Guttmann CR, Rousseau D, Sappey-Marinier D.

PLoS One. 2016 May 25;11(5):e0156405. doi: 10.1371/journal.pone.0156405. eCollection 2016.


Early Fiber Number Ratio Is a Surrogate of Corticospinal Tract Integrity and Predicts Motor Recovery After Stroke.

Bigourdan A, Munsch F, Coupé P, Guttmann CR, Sagnier S, Renou P, Debruxelles S, Poli M, Dousset V, Sibon I, Tourdias T.

Stroke. 2016 Apr;47(4):1053-9. doi: 10.1161/STROKEAHA.115.011576. Epub 2016 Mar 15.


Neural substrates of vulnerability to postsurgical delirium as revealed by presurgical diffusion MRI.

Cavallari M, Dai W, Guttmann CR, Meier DS, Ngo LH, Hshieh TT, Callahan AE, Fong TG, Schmitt E, Dickerson BC, Press DZ, Marcantonio ER, Jones RN, Inouye SK, Alsop DC; SAGES Study Group.

Brain. 2016 Apr;139(Pt 4):1282-94. doi: 10.1093/brain/aww010. Epub 2016 Feb 26.


Fatigue predicts disease worsening in relapsing-remitting multiple sclerosis patients.

Cavallari M, Palotai M, Glanz BI, Egorova S, Prieto JC, Healy BC, Chitnis T, Guttmann CR.

Mult Scler. 2016 Dec;22(14):1841-1849. Epub 2016 Feb 26.


Head circumference as a useful surrogate for intracranial volume in older adults.

Hshieh TT, Fox ML, Kosar CM, Cavallari M, Guttmann CR, Alsop D, Marcantonio ER, Schmitt EM, Jones RN, Inouye SK.

Int Psychogeriatr. 2016 Jan;28(1):157-62. doi: 10.1017/S104161021500037X.


Stroke Location Is an Independent Predictor of Cognitive Outcome.

Munsch F, Sagnier S, Asselineau J, Bigourdan A, Guttmann CR, Debruxelles S, Poli M, Renou P, Perez P, Dousset V, Sibon I, Tourdias T.

Stroke. 2016 Jan;47(1):66-73. doi: 10.1161/STROKEAHA.115.011242. Epub 2015 Nov 19.


Multiple sclerosis lesion formation and early evolution revisited: A weekly high-resolution magnetic resonance imaging study.

Guttmann CR, Rousset M, Roch JA, Hannoun S, Durand-Dubief F, Belaroussi B, Cavallari M, Rabilloud M, Sappey-Marinier D, Vukusic S, Cotton F.

Mult Scler. 2016 May;22(6):761-9. doi: 10.1177/1352458515600247. Epub 2015 Sep 11.


Handling changes in MRI acquisition parameters in modeling whole brain lesion volume and atrophy data in multiple sclerosis subjects: Comparison of linear mixed-effect models.

Chua AS, Egorova S, Anderson MC, Polgar-Turcsanyi M, Chitnis T, Weiner HL, Guttmann CR, Bakshi R, Healy BC.

Neuroimage Clin. 2015 Jul 2;8:606-10. doi: 10.1016/j.nicl.2015.06.009. eCollection 2015.


Using multiple imputation to efficiently correct cerebral MRI whole brain lesion and atrophy data in patients with multiple sclerosis.

Chua AS, Egorova S, Anderson MC, Polgar-Turcsanyi M, Chitnis T, Weiner HL, Guttmann CR, Bakshi R, Healy BC.

Neuroimage. 2015 Oct 1;119:81-8. doi: 10.1016/j.neuroimage.2015.06.037. Epub 2015 Jun 18.


Cardiovascular risk factors and small vessel disease of the brain: Blood pressure, white matter lesions, and functional decline in older persons.

Abraham HM, Wolfson L, Moscufo N, Guttmann CR, Kaplan RF, White WB.

J Cereb Blood Flow Metab. 2016 Jan;36(1):132-42. Review.


Brain atrophy and white-matter hyperintensities are not significantly associated with incidence and severity of postoperative delirium in older persons without dementia.

Cavallari M, Hshieh TT, Guttmann CR, Ngo LH, Meier DS, Schmitt EM, Marcantonio ER, Jones RN, Kosar CM, Fong TG, Press D, Inouye SK, Alsop DC; SAGES Study Group.

Neurobiol Aging. 2015 Jun;36(6):2122-9. doi: 10.1016/j.neurobiolaging.2015.02.024. Epub 2015 Feb 28.


Weekly multimodal MRI follow-up of two multiple sclerosis active lesions presenting a transient decrease in ADC.

Hannoun S, Roch JA, Durand-Dubief F, Vukusic S, Sappey-Marinier D, Guttmann CR, Cotton F.

Brain Behav. 2015 Feb;5(2):e00307. doi: 10.1002/brb3.307. Epub 2015 Jan 16.


An expanded composite scale of MRI-defined disease severity in multiple sclerosis: MRDSS2.

Bakshi R, Neema M, Tauhid S, Healy BC, Glanz BI, Kim G, Miller J, Berkowitz JL, Bove R, Houtchens MK, Severson C, Stankiewicz JM, Stazzone L, Chitnis T, Guttmann CR, Weiner HL, Ceccarelli A.

Neuroreport. 2014 Oct 1;25(14):1156-61. doi: 10.1097/WNR.0000000000000244.


Microstructural changes in the striatum and their impact on motor and neuropsychological performance in patients with multiple sclerosis.

Cavallari M, Ceccarelli A, Wang GY, Moscufo N, Hannoun S, Matulis CR, Jackson JS, Glanz BI, Bakshi R, Neema M, Guttmann CR.

PLoS One. 2014 Jul 21;9(7):e101199. doi: 10.1371/journal.pone.0101199. eCollection 2014.


Thalamic fractional anisotropy predicts accrual of cerebral white matter damage in older subjects with small-vessel disease.

Cavallari M, Moscufo N, Meier D, Skudlarski P, Pearlson GD, White WB, Wolfson L, Guttmann CR.

J Cereb Blood Flow Metab. 2014 Aug;34(8):1321-7. doi: 10.1038/jcbfm.2014.86. Epub 2014 May 14.


Treatment satisfaction, adherence and behavioral assessment in patients de-escalating from natalizumab to interferon β.

Zecca C, Riccitelli GC, Calabrese P, Pravatà E, Candrian U, Guttmann CR, Gobbi C.

BMC Neurol. 2014 Feb 28;14:38. doi: 10.1186/1471-2377-14-38.


Disconnection mechanism and regional cortical atrophy contribute to impaired processing of facial expressions and theory of mind in multiple sclerosis: a structural MRI study.

Mike A, Strammer E, Aradi M, Orsi G, Perlaki G, Hajnal A, Sandor J, Banati M, Illes E, Zaitsev A, Herold R, Guttmann CR, Illes Z.

PLoS One. 2013 Dec 13;8(12):e82422. doi: 10.1371/journal.pone.0082422. eCollection 2013.


Quantitative MRI analysis in children with multiple sclerosis: a multicenter feasibility pilot study.

Chitnis T, Guttmann CR, Zaitsev A, Musallam A, Weinstock-Guttman B, Yeh A, Rodriguez M, Ness J, Gorman MP, Healy BC, Kuntz N, Chabas D, Strober JB, Waubant E, Krupp L, Pelletier D, Erickson B, Bergsland N, Zivadinov R; U.S. Network of Pediatric MS Centers of Excellence.

BMC Neurol. 2013 Nov 13;13:173. doi: 10.1186/1471-2377-13-173.


Mobility impairment is associated with reduced microstructural integrity of the inferior and superior cerebellar peduncles in elderly with no clinical signs of cerebellar dysfunction.

Cavallari M, Moscufo N, Skudlarski P, Meier D, Panzer VP, Pearlson GD, White WB, Wolfson L, Guttmann CR.

Neuroimage Clin. 2013 Mar 1;2:332-40. doi: 10.1016/j.nicl.2013.02.003. eCollection 2013.


Clinical relevance and functional consequences of the TNFRSF1A multiple sclerosis locus.

Ottoboni L, Frohlich IY, Lee M, Healy BC, Keenan BT, Xia Z, Chitnis T, Guttmann CR, Khoury SJ, Weiner HL, Hafler DA, De Jager PL.

Neurology. 2013 Nov 26;81(22):1891-9. doi: 10.1212/01.wnl.0000436612.66328.8a. Epub 2013 Oct 30.


Impaired cerebrovascular hemodynamics are associated with cerebral white matter damage.

Purkayastha S, Fadar O, Mehregan A, Salat DH, Moscufo N, Meier DS, Guttmann CR, Fisher ND, Lipsitz LA, Sorond FA.

J Cereb Blood Flow Metab. 2014 Feb;34(2):228-34. doi: 10.1038/jcbfm.2013.180. Epub 2013 Oct 16.


White matter changes in patients with friedreich ataxia after treatment with erythropoietin.

Egger K, Clemm von Hohenberg C, Schocke MF, Guttmann CR, Wassermann D, Wigand MC, Nachbauer W, Kremser C, Sturm B, Scheiber-Mojdehkar B, Kubicki M, Shenton ME, Boesch S.

J Neuroimaging. 2014 Sep-Oct;24(5):504-8. doi: 10.1111/jon.12050. Epub 2013 Sep 9.


Interferon beta 1b following natalizumab discontinuation: one year, randomized, prospective, pilot trial.

Gobbi C, Meier DS, Cotton F, Sintzel M, Leppert D, Guttmann CR, Zecca C.

BMC Neurol. 2013 Aug 2;13:101. doi: 10.1186/1471-2377-13-101.


Processing speed in normal aging: effects of white matter hyperintensities and hippocampal volume loss.

Papp KV, Kaplan RF, Springate B, Moscufo N, Wakefield DB, Guttmann CR, Wolfson L.

Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2014;21(2):197-213. doi: 10.1080/13825585.2013.795513. Epub 2013 Jul 29.


No sex-specific difference in disease trajectory in multiple sclerosis patients before and after age 50.

Bove R, Musallam A, Healy BC, Houtchens M, Glanz BI, Khoury S, Guttmann CR, De Jager PL, Chitnis T.

BMC Neurol. 2013 Jul 3;13:73. doi: 10.1186/1471-2377-13-73.


Rapid buildup of brain white matter hyperintensities over 4 years linked to ambulatory blood pressure, mobility, cognition, and depression in old persons.

Wolfson L, Wakefield DB, Moscufo N, Kaplan RF, Hall CB, Schmidt JA, Guttmann CR, White WB.

J Gerontol A Biol Sci Med Sci. 2013 Nov;68(11):1387-94. doi: 10.1093/gerona/glt072. Epub 2013 Jun 13.


Radial diffusivity in the cerebellar peduncles correlates with clinical severity in Friedreich ataxia.

Clemm von Hohenberg C, Schocke MF, Wigand MC, Nachbauer W, Guttmann CR, Kubicki M, Shenton ME, Boesch S, Egger K.

Neurol Sci. 2013 Aug;34(8):1459-62. doi: 10.1007/s10072-013-1402-0. Epub 2013 May 3.


Multiple sclerosis susceptibility loci do not alter clinical and MRI outcomes in clinically isolated syndrome.

Kalincik T, Guttmann CR, Krasensky J, Vaneckova M, Lelkova P, Tyblova M, Seidl Z, De Jager PL, Havrdova E, Horakova D.

Genes Immun. 2013 Jun;14(4):244-8. doi: 10.1038/gene.2013.17. Epub 2013 Apr 11.


INtensive versus standard ambulatory blood pressure lowering to prevent functional DeclINe in the ElderlY (INFINITY).

White WB, Marfatia R, Schmidt J, Wakefield DB, Kaplan RF, Bohannon RW, Hall CB, Guttmann CR, Moscufo N, Fellows D, Wolfson L.

Am Heart J. 2013 Mar;165(3):258-265.e1. doi: 10.1016/j.ahj.2012.11.008. Epub 2013 Jan 5.


The impact of lesion in-painting and registration methods on voxel-based morphometry in detecting regional cerebral gray matter atrophy in multiple sclerosis.

Ceccarelli A, Jackson JS, Tauhid S, Arora A, Gorky J, Dell'Oglio E, Bakshi A, Chitnis T, Khoury SJ, Weiner HL, Guttmann CR, Bakshi R, Neema M.

AJNR Am J Neuroradiol. 2012 Sep;33(8):1579-85. doi: 10.3174/ajnr.A3083. Epub 2012 Mar 29.


Diffusion tensor-MRI evidence for extra-axonal neuronal degeneration in caudate and thalamic nuclei of patients with multiple sclerosis.

Hannoun S, Durand-Dubief F, Confavreux C, Ibarrola D, Streichenberger N, Cotton F, Guttmann CR, Sappey-Marinier D.

AJNR Am J Neuroradiol. 2012 Aug;33(7):1363-8. doi: 10.3174/ajnr.A2983. Epub 2012 Mar 1.


Daclizumab use in patients with pediatric multiple sclerosis.

Gorman MP, Tillema JM, Ciliax AM, Guttmann CR, Chitnis T.

Arch Neurol. 2012 Jan;69(1):78-81. doi: 10.1001/archneurol.2011.581.


Magnetic resonance disease severity scale (MRDSS) for patients with multiple sclerosis: a longitudinal study.

Moodie J, Healy BC, Buckle GJ, Gauthier SA, Glanz BI, Arora A, Ceccarelli A, Tauhid S, Han XM, Venkataraman A, Chitnis T, Khoury SJ, Guttmann CR, Weiner HL, Neema M, Bakshi R.

J Neurol Sci. 2012 Apr 15;315(1-2):49-54. doi: 10.1016/j.jns.2011.11.040. Epub 2011 Dec 28.


Average daily blood pressure, not office blood pressure, is associated with progression of cerebrovascular disease and cognitive decline in older people.

White WB, Wolfson L, Wakefield DB, Hall CB, Campbell P, Moscufo N, Schmidt J, Kaplan RF, Pearlson G, Guttmann CR.

Circulation. 2011 Nov 22;124(21):2312-9. doi: 10.1161/CIRCULATIONAHA.111.037036.

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