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Items: 1 to 50 of 294

1.

Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments.

Masson GR, Burke JE, Ahn NG, Anand GS, Borchers C, Brier S, Bou-Assaf GM, Engen JR, Englander SW, Faber J, Garlish R, Griffin PR, Gross ML, Guttman M, Hamuro Y, Heck AJR, Houde D, Iacob RE, Jørgensen TJD, Kaltashov IA, Klinman JP, Konermann L, Man P, Mayne L, Pascal BD, Reichmann D, Skehel M, Snijder J, Strutzenberg TS, Underbakke ES, Wagner C, Wales TE, Walters BT, Weis DD, Wilson DJ, Wintrode PL, Zhang Z, Zheng J, Schriemer DC, Rand KD.

Nat Methods. 2019 Jul;16(7):595-602. doi: 10.1038/s41592-019-0459-y. Epub 2019 Jun 27. Review.

2.

Applications of a deep learning method for anti-aliasing and super-resolution in MRI.

Zhao C, Shao M, Carass A, Li H, Dewey BE, Ellingsen LM, Woo J, Guttman MA, Blitz AM, Stone M, Calabresi PA, Halperin H, Prince JL.

Magn Reson Imaging. 2019 Jun 24. pii: S0730-725X(18)30650-7. doi: 10.1016/j.mri.2019.05.038. [Epub ahead of print]

PMID:
31247254
3.

Concentration, distribution, and influence of aging on the 18 kDa translocator protein in human brain: Implications for brain imaging studies.

Tong J, Williams B, Rusjan PM, Mizrahi R, Lacapère JJ, McCluskey T, Furukawa Y, Guttman M, Ang LC, Boileau I, Meyer JH, Kish SJ.

J Cereb Blood Flow Metab. 2019 Jun 20:271678X19858003. doi: 10.1177/0271678X19858003. [Epub ahead of print]

PMID:
31220997
4.

The bipartite TAD organization of the X-inactivation center ensures opposing developmental regulation of Tsix and Xist.

van Bemmel JG, Galupa R, Gard C, Servant N, Picard C, Davies J, Szempruch AJ, Zhan Y, Żylicz JJ, Nora EP, Lameiras S, de Wit E, Gentien D, Baulande S, Giorgetti L, Guttman M, Hughes JR, Higgs DR, Gribnau J, Heard E.

Nat Genet. 2019 Jun;51(6):1024-1034. doi: 10.1038/s41588-019-0412-0. Epub 2019 May 27.

PMID:
31133748
5.

Phase separation drives X-chromosome inactivation: a hypothesis.

Cerase A, Armaos A, Neumayer C, Avner P, Guttman M, Tartaglia GG.

Nat Struct Mol Biol. 2019 May;26(5):331-334. doi: 10.1038/s41594-019-0223-0. No abstract available.

PMID:
31061525
6.

Compassion Fatigue in Surgical Trainees.

Seemann NM, Karanicolas PJ, Guttman MP, Nathens AB, Tien HC, Ellis J, Zaretsky A, Gotlib Conn L.

J Surg Educ. 2019 Apr 9. pii: S1931-7204(18)30754-2. doi: 10.1016/j.jsurg.2019.03.012. [Epub ahead of print]

PMID:
30979650
7.

Inspiratory Myoclonus.

Dekker MCJ, Kilonzo KG, Howlett WP, Guttman M, Cubo E.

Tremor Other Hyperkinet Mov (N Y). 2019 Feb 18;9:625. doi: 10.7916/3qs5-cv76. eCollection 2019.

8.

Ablation Lesion Characterization in Scarred Substrate Assessed Using Cardiac Magnetic Resonance.

Tao S, Guttman MA, Fink S, Elahi H, Patil KD, Ashikaga H, Kolandaivelu AD, Berger RD, Halushka MK, Schmidt EJ, Herzka DA, Halperin HR.

JACC Clin Electrophysiol. 2019 Jan;5(1):91-100. doi: 10.1016/j.jacep.2018.11.001. Epub 2018 Dec 26.

PMID:
30678791
9.

Tracking Higher Order Protein Structure by Hydrogen-Deuterium Exchange Mass Spectrometry.

Benhaim M, Lee KK, Guttman M.

Protein Pept Lett. 2019;26(1):16-26. doi: 10.2174/0929866526666181212165037. Review.

PMID:
30543159
10.

The ubiquitin ligase SspH1 from Salmonella uses a modular and dynamic E3 domain to catalyze substrate ubiquitylation.

Cook M, Delbecq SP, Schweppe TP, Guttman M, Klevit RE, Brzovic PS.

J Biol Chem. 2019 Jan 18;294(3):783-793. doi: 10.1074/jbc.RA118.004247. Epub 2018 Nov 20.

PMID:
30459234
11.

Publisher Correction: The NORAD lncRNA assembles a topoisomerase complex critical for genome stability.

Munschauer M, Nguyen CT, Sirokman K, Hartigan CR, Hogstrom L, Engreitz JM, Ulirsch JC, Fulco CP, Subramanian V, Chen J, Schenone M, Guttman M, Carr SA, Lander ES.

Nature. 2018 Nov;563(7733):E32. doi: 10.1038/s41586-018-0584-2.

PMID:
30279576
12.

Dissection of Fragmentation Pathways in Protonated N-Acetylhexosamines.

Mookherjee A, Uppal SS, Guttman M.

Anal Chem. 2018 Oct 16;90(20):11883-11891. doi: 10.1021/acs.analchem.8b01963. Epub 2018 Sep 25.

13.

The NORAD lncRNA assembles a topoisomerase complex critical for genome stability.

Munschauer M, Nguyen CT, Sirokman K, Hartigan CR, Hogstrom L, Engreitz JM, Ulirsch JC, Fulco CP, Subramanian V, Chen J, Schenone M, Guttman M, Carr SA, Lander ES.

Nature. 2018 Sep;561(7721):132-136. doi: 10.1038/s41586-018-0453-z. Epub 2018 Aug 27. Erratum in: Nature. 2018 Oct 2;:.

PMID:
30150775
14.

Higher-Order Inter-chromosomal Hubs Shape 3D Genome Organization in the Nucleus.

Quinodoz SA, Ollikainen N, Tabak B, Palla A, Schmidt JM, Detmar E, Lai MM, Shishkin AA, Bhat P, Takei Y, Trinh V, Aznauryan E, Russell P, Cheng C, Jovanovic M, Chow A, Cai L, McDonel P, Garber M, Guttman M.

Cell. 2018 Jul 26;174(3):744-757.e24. doi: 10.1016/j.cell.2018.05.024. Epub 2018 Jun 7.

PMID:
29887377
15.

Regional myocardial strain measurements from 4DCT in patients with normal LV function.

McVeigh ER, Pourmorteza A, Guttman M, Sandfort V, Contijoch F, Budhiraja S, Chen Z, Bluemke DA, Chen MY.

J Cardiovasc Comput Tomogr. 2018 Sep - Oct;12(5):372-378. doi: 10.1016/j.jcct.2018.05.002. Epub 2018 May 9.

16.

The Promise of Telemedicine for Movement Disorders: an Interdisciplinary Approach.

Ben-Pazi H, Browne P, Chan P, Cubo E, Guttman M, Hassan A, Hatcher-Martin J, Mari Z, Moukheiber E, Okubadejo NU, Shalash A; International Parkinson and Movement Disorder Society Telemedicine Task Force.

Curr Neurol Neurosci Rep. 2018 Apr 13;18(5):26. doi: 10.1007/s11910-018-0834-6. Review.

PMID:
29654523
17.

Telemedicine Use for Movement Disorders: A Global Survey.

Hassan A, Dorsey ER, Goetz CG, Bloem BR, Guttman M, Tanner CM, Mari Z, Pantelyat A, Galifianakis NB, Bajwa JA, Gatto EM, Cubo E.

Telemed J E Health. 2018 Dec;24(12):979-992. doi: 10.1089/tmj.2017.0295. Epub 2018 Mar 22.

PMID:
29565764
18.

Conformational dynamics of P-glycoprotein in lipid nanodiscs and detergent micelles reveal complex motions on a wide time scale.

Li MJ, Guttman M, Atkins WM.

J Biol Chem. 2018 Apr 27;293(17):6297-6307. doi: 10.1074/jbc.RA118.002190. Epub 2018 Mar 6.

19.

Bridging the structural gap of glycoproteomics with ion mobility spectrometry.

Mookherjee A, Guttman M.

Curr Opin Chem Biol. 2018 Feb;42:86-92. doi: 10.1016/j.cbpa.2017.11.012. Epub 2017 Dec 1. Review.

PMID:
29202341
20.

Corrigendum: The 4D nucleome project.

Dekker J, Belmont AS, Guttman M, Leshyk VO, Lis JT, Lomvardas S, Mirny LA, O'Shea CC, Park PJ, Ren B, Politz JCR, Shendure J, Zhong S; 4D Nucleome Network.

Nature. 2017 Dec 14;552(7684):278. doi: 10.1038/nature24667. Epub 2017 Nov 22.

PMID:
29168505
21.

RAP-MS: A Method to Identify Proteins that Interact Directly with a Specific RNA Molecule in Cells.

McHugh CA, Guttman M.

Methods Mol Biol. 2018;1649:473-488. doi: 10.1007/978-1-4939-7213-5_31.

PMID:
29130217
22.

Telemedicine Enables Broader Access to Movement Disorders Curricula for Medical Students.

Cubo E, Doumbe J, López E, Lopez GA, Gatto E, Persi G, Guttman M.

Tremor Other Hyperkinet Mov (N Y). 2017 Oct 19;7:501. doi: 10.7916/D8708CXW. eCollection 2017.

23.

Brain monoamine oxidase B and A in human parkinsonian dopamine deficiency disorders.

Tong J, Rathitharan G, Meyer JH, Furukawa Y, Ang LC, Boileau I, Guttman M, Hornykiewicz O, Kish SJ.

Brain. 2017 Sep 1;140(9):2460-2474. doi: 10.1093/brain/awx172.

PMID:
29050386
24.

The 4D nucleome project.

Dekker J, Belmont AS, Guttman M, Leshyk VO, Lis JT, Lomvardas S, Mirny LA, O'Shea CC, Park PJ, Ren B, Politz JCR, Shendure J, Zhong S; 4D Nucleome Network.

Nature. 2017 Sep 13;549(7671):219-226. doi: 10.1038/nature23884. Erratum in: Nature. 2017 Nov 22;:.

25.

Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization.

Torrents de la Peña A, Julien JP, de Taeye SW, Garces F, Guttman M, Ozorowski G, Pritchard LK, Behrens AJ, Go EP, Burger JA, Schermer EE, Sliepen K, Ketas TJ, Pugach P, Yasmeen A, Cottrell CA, Torres JL, Vavourakis CD, van Gils MJ, LaBranche C, Montefiori DC, Desaire H, Crispin M, Klasse PJ, Lee KK, Moore JP, Ward AB, Wilson IA, Sanders RW.

Cell Rep. 2017 Aug 22;20(8):1805-1817. doi: 10.1016/j.celrep.2017.07.077.

26.

Extracellular Matrix Proteins Mediate HIV-1 gp120 Interactions with α4β7.

Plotnik D, Guo W, Cleveland B, von Haller P, Eng JK, Guttman M, Lee KK, Arthos J, Hu SL.

J Virol. 2017 Oct 13;91(21). pii: e01005-17. doi: 10.1128/JVI.01005-17. Print 2017 Nov 1.

27.

Response to Comment on "Xist recruits the X chromosome to the nuclear lamina to enable chromosome-wide silencing".

Chen CK, Chow A, Lai M, Guttman M.

Science. 2017 Jun 16;356(6343). pii: eaam5439. doi: 10.1126/science.aam5439.

PMID:
28619888
28.

Non-contrast-enhanced T1 -weighted MRI of myocardial radiofrequency ablation lesions.

Guttman MA, Tao S, Fink S, Kolandaivelu A, Halperin HR, Herzka DA.

Magn Reson Med. 2018 Feb;79(2):879-889. doi: 10.1002/mrm.26750. Epub 2017 May 11.

29.

Serotonin and dopamine transporter PET changes in the premotor phase of LRRK2 parkinsonism: cross-sectional studies.

Wile DJ, Agarwal PA, Schulzer M, Mak E, Dinelle K, Shahinfard E, Vafai N, Hasegawa K, Zhang J, McKenzie J, Neilson N, Strongosky A, Uitti RJ, Guttman M, Zabetian CP, Ding YS, Adam M, Aasly J, Wszolek ZK, Farrer M, Sossi V, Stoessl AJ.

Lancet Neurol. 2017 May;16(5):351-359. doi: 10.1016/S1474-4422(17)30056-X. Epub 2017 Mar 20.

30.

Gas-Phase Hydrogen/Deuterium Exchange for Distinguishing Isomeric Carbohydrate Ions.

Uppal SS, Beasley SE, Scian M, Guttman M.

Anal Chem. 2017 Apr 18;89(8):4737-4742. doi: 10.1021/acs.analchem.7b00683. Epub 2017 Mar 29.

PMID:
28304155
31.

Re-evaluating the foundations of lncRNA-Polycomb function.

Blanco MR, Guttman M.

EMBO J. 2017 Apr 13;36(8):964-966. doi: 10.15252/embj.201796796. Epub 2017 Mar 15. No abstract available.

32.

Linking Protein and RNA Function within the Same Gene.

Szempruch A, Guttman M.

Cell. 2017 Feb 23;168(5):753-755. doi: 10.1016/j.cell.2017.02.014.

33.

Quantitative predictions of protein interactions with long noncoding RNAs.

Cirillo D, Blanco M, Armaos A, Buness A, Avner P, Guttman M, Cerase A, Tartaglia GG.

Nat Methods. 2016 Dec 29;14(1):5-6. doi: 10.1038/nmeth.4100. No abstract available.

PMID:
28032625
34.

A randomized, double-blind, placebo-controlled trial of coenzyme Q10 in Huntington disease.

McGarry A, McDermott M, Kieburtz K, de Blieck EA, Beal F, Marder K, Ross C, Shoulson I, Gilbert P, Mallonee WM, Guttman M, Wojcieszek J, Kumar R, LeDoux MS, Jenkins M, Rosas HD, Nance M, Biglan K, Como P, Dubinsky RM, Shannon KM, O'Suilleabhain P, Chou K, Walker F, Martin W, Wheelock VL, McCusker E, Jankovic J, Singer C, Sanchez-Ramos J, Scott B, Suchowersky O, Factor SA, Higgins DS Jr, Molho E, Revilla F, Caviness JN, Friedman JH, Perlmutter JS, Feigin A, Anderson K, Rodriguez R, McFarland NR, Margolis RL, Farbman ES, Raymond LA, Suski V, Kostyk S, Colcher A, Seeberger L, Epping E, Esmail S, Diaz N, Fung WL, Diamond A, Frank S, Hanna P, Hermanowicz N, Dure LS, Cudkowicz M; Huntington Study Group 2CARE Investigators and Coordinators.

Neurology. 2017 Jan 10;88(2):152-159. doi: 10.1212/WNL.0000000000003478. Epub 2016 Dec 2.

35.

Regular Exercise, Quality of Life, and Mobility in Parkinson's Disease: A Longitudinal Analysis of National Parkinson Foundation Quality Improvement Initiative Data.

Rafferty MR, Schmidt PN, Luo ST, Li K, Marras C, Davis TL, Guttman M, Cubillos F, Simuni T; all NPF-QII Investigators.

J Parkinsons Dis. 2017;7(1):193-202. doi: 10.3233/JPD-160912.

36.

Local regulation of gene expression by lncRNA promoters, transcription and splicing.

Engreitz JM, Haines JE, Perez EM, Munson G, Chen J, Kane M, McDonel PE, Guttman M, Lander ES.

Nature. 2016 Nov 17;539(7629):452-455. doi: 10.1038/nature20149. Epub 2016 Oct 26.

PMID:
27783602
37.

Long non-coding RNAs: spatial amplifiers that control nuclear structure and gene expression.

Engreitz JM, Ollikainen N, Guttman M.

Nat Rev Mol Cell Biol. 2016 Dec;17(12):756-770. doi: 10.1038/nrm.2016.126. Epub 2016 Oct 26. Review.

PMID:
27780979
38.

Xist recruits the X chromosome to the nuclear lamina to enable chromosome-wide silencing.

Chen CK, Blanco M, Jackson C, Aznauryan E, Ollikainen N, Surka C, Chow A, Cerase A, McDonel P, Guttman M.

Science. 2016 Oct 28;354(6311):468-472. Epub 2016 Aug 4.

PMID:
27492478
39.

A Magnetic Resonance Imaging-Conditional External Cardiac Defibrillator for Resuscitation Within the Magnetic Resonance Imaging Scanner Bore.

Schmidt EJ, Watkins RD, Zviman MM, Guttman MA, Wang W, Halperin HA.

Circ Cardiovasc Imaging. 2016 Oct;9(10). pii: e005091.

40.

Sequential and Simultaneous Immunization of Rabbits with HIV-1 Envelope Glycoprotein SOSIP.664 Trimers from Clades A, B and C.

Klasse PJ, LaBranche CC, Ketas TJ, Ozorowski G, Cupo A, Pugach P, Ringe RP, Golabek M, van Gils MJ, Guttman M, Lee KK, Wilson IA, Butera ST, Ward AB, Montefiori DC, Sanders RW, Moore JP.

PLoS Pathog. 2016 Sep 14;12(9):e1005864. doi: 10.1371/journal.ppat.1005864. eCollection 2016 Sep.

41.

m(6)A RNA methylation promotes XIST-mediated transcriptional repression.

Patil DP, Chen CK, Pickering BF, Chow A, Jackson C, Guttman M, Jaffrey SR.

Nature. 2016 Sep 15;537(7620):369-373. doi: 10.1038/nature19342. Epub 2016 Sep 7.

42.

Epitope-Independent Purification of Native-Like Envelope Trimers from Diverse HIV-1 Isolates.

Verkerke HP, Williams JA, Guttman M, Simonich CA, Liang Y, Filipavicius M, Hu SL, Overbaugh J, Lee KK.

J Virol. 2016 Sep 29;90(20):9471-82. doi: 10.1128/JVI.01351-16. Print 2016 Oct 15.

43.

The Myeloablative Drug Busulfan Converts Cysteine to Dehydroalanine and Lanthionine in Redoxins.

Scian M, Guttman M, Bouldin SD, Outten CE, Atkins WM.

Biochemistry. 2016 Aug 23;55(33):4720-30. doi: 10.1021/acs.biochem.6b00622. Epub 2016 Aug 11.

44.

Changes in Structure and Antigenicity of HIV-1 Env Trimers Resulting from Removal of a Conserved CD4 Binding Site-Proximal Glycan.

Liang Y, Guttman M, Williams JA, Verkerke H, Alvarado D, Hu SL, Lee KK.

J Virol. 2016 Sep 29;90(20):9224-36. doi: 10.1128/JVI.01116-16. Print 2016 Oct 15.

45.

Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV.

Joyce MG, Zhang B, Ou L, Chen M, Chuang GY, Druz A, Kong WP, Lai YT, Rundlet EJ, Tsybovsky Y, Yang Y, Georgiev IS, Guttman M, Lees CR, Pancera M, Sastry M, Soto C, Stewart-Jones GBE, Thomas PV, Van Galen JG, Baxa U, Lee KK, Mascola JR, Graham BS, Kwong PD.

Nat Struct Mol Biol. 2016 Sep;23(9):811-820. doi: 10.1038/nsmb.3267. Epub 2016 Aug 1.

46.

Somatic Hypermutation-Induced Changes in the Structure and Dynamics of HIV-1 Broadly Neutralizing Antibodies.

Davenport TM, Gorman J, Joyce MG, Zhou T, Soto C, Guttman M, Moquin S, Yang Y, Zhang B, Doria-Rose NA, Hu SL, Mascola JR, Kwong PD, Lee KK.

Structure. 2016 Aug 2;24(8):1346-1357. doi: 10.1016/j.str.2016.06.012. Epub 2016 Jul 28.

47.

Health Care Delivery Practices in Huntington's Disease Specialty Clinics: An International Survey.

Frich JC, Rae D, Roxburgh R, Miedzybrodzka ZH, Edmondson M, Pope EB, Goodman L, Haddad MS, Giuliano J, Nelson EC, Guttman M, Nance M.

J Huntingtons Dis. 2016 Jun 27;5(2):207-13. doi: 10.3233/JHD-160192.

48.

Longitudinal Changes in the Motor Learning-Related Brain Activation Response in Presymptomatic Huntington's Disease.

Holtbernd F, Tang CC, Feigin A, Dhawan V, Ghilardi MF, Paulsen JS, Guttman M, Eidelberg D.

PLoS One. 2016 May 18;11(5):e0154742. doi: 10.1371/journal.pone.0154742. eCollection 2016.

49.

Site-Specific Mapping of Sialic Acid Linkage Isomers by Ion Mobility Spectrometry.

Guttman M, Lee KK.

Anal Chem. 2016 May 17;88(10):5212-7. doi: 10.1021/acs.analchem.6b00265. Epub 2016 May 2.

50.

A Guide to Packing Your DNA.

Dekker J, Guttman M, Lomvardas S.

Cell. 2016 Apr 7;165(2):259-61. doi: 10.1016/j.cell.2016.03.039.

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