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Items: 33


The liquid biopsy: towards standardisation in preparation for prime time.

Page K, Shaw JA, Guttery DS.

Lancet Oncol. 2019 Jun;20(6):758-760. doi: 10.1016/S1470-2045(19)30310-9. No abstract available.


Alcoholism Identification Based on an AlexNet Transfer Learning Model.

Wang SH, Xie S, Chen X, Guttery DS, Tang C, Sun J, Zhang YD.

Front Psychiatry. 2019 Apr 11;10:205. doi: 10.3389/fpsyt.2019.00205. eCollection 2019.


Personalized Detection of Circulating Tumor DNA Antedates Breast Cancer Metastatic Recurrence.

Coombes RC, Page K, Salari R, Hastings RK, Armstrong A, Ahmed S, Ali S, Cleator S, Kenny L, Stebbing J, Rutherford M, Sethi H, Boydell A, Swenerton R, Fernandez-Garcia D, Gleason KLT, Goddard K, Guttery DS, Assaf ZJ, Wu HT, Natarajan P, Moore DA, Primrose L, Dashner S, Tin AS, Balcioglu M, Srinivasan R, Shchegrova SV, Olson A, Hafez D, Billings P, Aleshin A, Rehman F, Toghill BJ, Hills A, Louie MC, Lin CJ, Zimmermann BG, Shaw JA.

Clin Cancer Res. 2019 Jul 15;25(14):4255-4263. doi: 10.1158/1078-0432.CCR-18-3663. Epub 2019 Apr 16.


Plasmodium centrin PbCEN-4 localizes to the putative MTOC and is dispensable for malaria parasite proliferation.

Roques M, Stanway RR, Rea EI, Markus R, Brady D, Holder AA, Guttery DS, Tewari R.

Biol Open. 2019 Jan 29;8(1). pii: bio036822. doi: 10.1242/bio.036822.


Circulating tumor DNA in patients with colorectal adenomas: assessment of detectability and genetic heterogeneity.

Myint NNM, Verma AM, Fernandez-Garcia D, Sarmah P, Tarpey PS, Al-Aqbi SS, Cai H, Trigg R, West K, Howells LM, Thomas A, Brown K, Guttery DS, Singh B, Pringle HJ, McDermott U, Shaw JA, Rufini A.

Cell Death Dis. 2018 Aug 30;9(9):894. doi: 10.1038/s41419-018-0934-x.


Author Correction: Plasmodium APC3 mediates chromosome condensation and cytokinesis during atypical mitosis in male gametogenesis.

Wall RJ, Ferguson DJP, Freville A, Franke-Fayard B, Brady D, Zeeshan M, Bottrill AR, Wheatley S, Fry AM, Janse CJ, Yamano H, Holder AA, Guttery DS, Tewari R.

Sci Rep. 2018 Aug 21;8(1):12814. doi: 10.1038/s41598-018-30924-6.


Correction to: Association of invasion-promoting tenascin-C additional domains with breast cancers in young women.

Guttery DS, Hancox RA, Mulligan KT, Hughes S, Lambe SM, Howard Pringle J, Walker RA, Louise Jones J, Shaw JA.

Breast Cancer Res. 2018 Aug 1;20(1):80. doi: 10.1186/s13058-018-0997-8.


Racial differences in endometrial cancer molecular portraits in The Cancer Genome Atlas.

Guttery DS, Blighe K, Polymeros K, Symonds RP, Macip S, Moss EL.

Oncotarget. 2018 Mar 30;9(24):17093-17103. doi: 10.18632/oncotarget.24907. eCollection 2018 Mar 30.


Plasmodium APC3 mediates chromosome condensation and cytokinesis during atypical mitosis in male gametogenesis.

Wall RJ, Ferguson DJP, Freville A, Franke-Fayard B, Brady D, Zeeshan M, Bottrill AR, Wheatley S, Fry AM, Janse CJ, Yamano H, Holder AA, Guttery DS, Tewari R.

Sci Rep. 2018 Apr 4;8(1):5610. doi: 10.1038/s41598-018-23871-9. Erratum in: Sci Rep. 2018 Aug 21;8(1):12814.


Photosensitized INA-Labelled protein 1 (PhIL1) is novel component of the inner membrane complex and is required for Plasmodium parasite development.

Saini E, Zeeshan M, Brady D, Pandey R, Kaiser G, Koreny L, Kumar P, Thakur V, Tatiya S, Katris NJ, Limenitakis RS, Kaur I, Green JL, Bottrill AR, Guttery DS, Waller RF, Heussler V, Holder AA, Mohmmed A, Malhotra P, Tewari R.

Sci Rep. 2017 Nov 14;7(1):15577. doi: 10.1038/s41598-017-15781-z.


The genetics of gastroesophageal adenocarcinoma and the use of circulating cell free DNA for disease detection and monitoring.

Openshaw MR, Richards CJ, Guttery DS, Shaw JA, Thomas AL.

Expert Rev Mol Diagn. 2017 May;17(5):459-470. doi: 10.1080/14737159.2017.1308824. Epub 2017 Mar 30. Review.


Next Generation Sequencing of Circulating Cell-Free DNA for Evaluating Mutations and Gene Amplification in Metastatic Breast Cancer.

Page K, Guttery DS, Fernandez-Garcia D, Hills A, Hastings RK, Luo J, Goddard K, Shahin V, Woodley-Barker L, Rosales BM, Coombes RC, Stebbing J, Shaw JA.

Clin Chem. 2017 Feb;63(2):532-541. doi: 10.1373/clinchem.2016.261834. Epub 2016 Dec 9.


Mutation Analysis of Cell-Free DNA and Single Circulating Tumor Cells in Metastatic Breast Cancer Patients with High Circulating Tumor Cell Counts.

Shaw JA, Guttery DS, Hills A, Fernandez-Garcia D, Page K, Rosales BM, Goddard KS, Hastings RK, Luo J, Ogle O, Woodley L, Ali S, Stebbing J, Coombes RC.

Clin Cancer Res. 2017 Jan 1;23(1):88-96. doi: 10.1158/1078-0432.CCR-16-0825. Epub 2016 Jun 22.


Plasmodium P-Type Cyclin CYC3 Modulates Endomitotic Growth during Oocyst Development in Mosquitoes.

Roques M, Wall RJ, Douglass AP, Ramaprasad A, Ferguson DJ, Kaindama ML, Brusini L, Joshi N, Rchiad Z, Brady D, Guttery DS, Wheatley SP, Yamano H, Holder AA, Pain A, Wickstead B, Tewari R.

PLoS Pathog. 2015 Nov 13;11(11):e1005273. doi: 10.1371/journal.ppat.1005273. eCollection 2015 Nov.


Commit and Transmit: Molecular Players in Plasmodium Sexual Development and Zygote Differentiation.

Guttery DS, Roques M, Holder AA, Tewari R.

Trends Parasitol. 2015 Dec;31(12):676-685. doi: 10.1016/ Epub 2015 Oct 1. Review.


Noninvasive detection of activating estrogen receptor 1 (ESR1) mutations in estrogen receptor-positive metastatic breast cancer.

Guttery DS, Page K, Hills A, Woodley L, Marchese SD, Rghebi B, Hastings RK, Luo J, Pringle JH, Stebbing J, Coombes RC, Ali S, Shaw JA.

Clin Chem. 2015 Jul;61(7):974-82. doi: 10.1373/clinchem.2015.238717. Epub 2015 May 15.


Whole genome sequence analysis suggests intratumoral heterogeneity in dissemination of breast cancer to lymph nodes.

Blighe K, Kenny L, Patel N, Guttery DS, Page K, Gronau JH, Golshani C, Stebbing J, Coombes RC, Shaw JA.

PLoS One. 2014 Dec 29;9(12):e115346. doi: 10.1371/journal.pone.0115346. eCollection 2014.


NEOCENT: a randomised feasibility and translational study comparing neoadjuvant endocrine therapy with chemotherapy in ER-rich postmenopausal primary breast cancer.

Palmieri C, Cleator S, Kilburn LS, Kim SB, Ahn SH, Beresford M, Gong G, Mansi J, Mallon E, Reed S, Mousa K, Fallowfield L, Cheang M, Morden J, Page K, Guttery DS, Rghebi B, Primrose L, Shaw JA, Thompson AM, Bliss JM, Coombes RC.

Breast Cancer Res Treat. 2014 Dec;148(3):581-90. doi: 10.1007/s10549-014-3183-4. Epub 2014 Nov 14.


Genome-wide functional analysis of Plasmodium protein phosphatases reveals key regulators of parasite development and differentiation.

Guttery DS, Poulin B, Ramaprasad A, Wall RJ, Ferguson DJ, Brady D, Patzewitz EM, Whipple S, Straschil U, Wright MH, Mohamed AM, Radhakrishnan A, Arold ST, Tate EW, Holder AA, Wickstead B, Pain A, Tewari R.

Cell Host Microbe. 2014 Jul 9;16(1):128-40. doi: 10.1016/j.chom.2014.05.020.


Unique apicomplexan IMC sub-compartment proteins are early markers for apical polarity in the malaria parasite.

Poulin B, Patzewitz EM, Brady D, Silvie O, Wright MH, Ferguson DJ, Wall RJ, Whipple S, Guttery DS, Tate EW, Wickstead B, Holder AA, Tewari R.

Biol Open. 2013 Sep 16;2(11):1160-70. doi: 10.1242/bio.20136163. eCollection 2013.


Influence of plasma processing on recovery and analysis of circulating nucleic acids.

Page K, Guttery DS, Zahra N, Primrose L, Elshaw SR, Pringle JH, Blighe K, Marchese SD, Hills A, Woodley L, Stebbing J, Coombes RC, Shaw JA.

PLoS One. 2013 Oct 18;8(10):e77963. doi: 10.1371/journal.pone.0077963. eCollection 2013.


The Plasmodium berghei Ca(2+)/H(+) exchanger, PbCAX, is essential for tolerance to environmental Ca(2+) during sexual development.

Guttery DS, Pittman JK, Frénal K, Poulin B, McFarlane LR, Slavic K, Wheatley SP, Soldati-Favre D, Krishna S, Tewari R, Staines HM.

PLoS Pathog. 2013 Feb;9(2):e1003191. doi: 10.1371/journal.ppat.1003191. Epub 2013 Feb 28.


An ancient protein phosphatase, SHLP1, is critical to microneme development in Plasmodium ookinetes and parasite transmission.

Patzewitz EM, Guttery DS, Poulin B, Ramakrishnan C, Ferguson DJ, Wall RJ, Brady D, Holder AA, Szöőr B, Tewari R.

Cell Rep. 2013 Mar 28;3(3):622-9. doi: 10.1016/j.celrep.2013.01.032. Epub 2013 Feb 21.


Hide and seek: tell-tale signs of breast cancer lurking in the blood.

Guttery DS, Blighe K, Page K, Marchese SD, Hills A, Coombes RC, Stebbing J, Shaw JA.

Cancer Metastasis Rev. 2013 Jun;32(1-2):289-302. doi: 10.1007/s10555-012-9414-4. Review.


A unique protein phosphatase with kelch-like domains (PPKL) in Plasmodium modulates ookinete differentiation, motility and invasion.

Guttery DS, Poulin B, Ferguson DJ, Szöőr B, Wickstead B, Carroll PL, Ramakrishnan C, Brady D, Patzewitz EM, Straschil U, Solyakov L, Green JL, Sinden RE, Tobin AB, Holder AA, Tewari R.

PLoS Pathog. 2012 Sep;8(9):e1002948. doi: 10.1371/journal.ppat.1002948. Epub 2012 Sep 20.


A putative homologue of CDC20/CDH1 in the malaria parasite is essential for male gamete development.

Guttery DS, Ferguson DJ, Poulin B, Xu Z, Straschil U, Klop O, Solyakov L, Sandrini SM, Brady D, Nieduszynski CA, Janse CJ, Holder AA, Tobin AB, Tewari R.

PLoS Pathog. 2012 Feb;8(2):e1002554. doi: 10.1371/journal.ppat.1002554. Epub 2012 Feb 23. Erratum in: PLoS Pathog. 2012 Mar;8(3). doi: 10.1371/annotation/ef70d427-0816-4a63-aeaf-874b734793b0.


Sexual development in Plasmodium: lessons from functional analyses.

Guttery DS, Holder AA, Tewari R.

PLoS Pathog. 2012 Jan;8(1):e1002404. doi: 10.1371/journal.ppat.1002404. Epub 2012 Jan 19. Review. No abstract available.


The presence of disseminated tumour cells in the bone marrow is inversely related to circulating free DNA in plasma in breast cancer dormancy.

Payne RE, Hava NL, Page K, Blighe K, Ward B, Slade M, Brown J, Guttery DS, Zaidi SA, Stebbing J, Jacob J, Yagüe E, Shaw JA, Coombes RC.

Br J Cancer. 2012 Jan 17;106(2):375-82. doi: 10.1038/bjc.2011.537. Epub 2011 Dec 13.


Detection of HER2 amplification in circulating free DNA in patients with breast cancer.

Page K, Hava N, Ward B, Brown J, Guttery DS, Ruangpratheep C, Blighe K, Sharma A, Walker RA, Coombes RC, Shaw JA.

Br J Cancer. 2011 Apr 12;104(8):1342-8. doi: 10.1038/bjc.2011.89. Epub 2011 Mar 22.


Expression of tenascin-C and its isoforms in the breast.

Guttery DS, Shaw JA, Lloyd K, Pringle JH, Walker RA.

Cancer Metastasis Rev. 2010 Dec;29(4):595-606. doi: 10.1007/s10555-010-9249-9. Review.


Association of invasion-promoting tenascin-C additional domains with breast cancers in young women.

Guttery DS, Hancox RA, Mulligan KT, Hughes S, Lambe SM, Pringle JH, Walker RA, Jones JL, Shaw JA.

Breast Cancer Res. 2010;12(4):R57. doi: 10.1186/bcr2618. Epub 2010 Aug 2. Erratum in: Breast Cancer Res. 2018 Aug 1;20(1):80.


Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia.

Russell LJ, Capasso M, Vater I, Akasaka T, Bernard OA, Calasanz MJ, Chandrasekaran T, Chapiro E, Gesk S, Griffiths M, Guttery DS, Haferlach C, Harder L, Heidenreich O, Irving J, Kearney L, Nguyen-Khac F, Machado L, Minto L, Majid A, Moorman AV, Morrison H, Rand V, Strefford JC, Schwab C, Tönnies H, Dyer MJ, Siebert R, Harrison CJ.

Blood. 2009 Sep 24;114(13):2688-98. doi: 10.1182/blood-2009-03-208397. Epub 2009 Jul 29.


Tumour-associated tenascin-C isoforms promote breast cancer cell invasion and growth by matrix metalloproteinase-dependent and independent mechanisms.

Hancox RA, Allen MD, Holliday DL, Edwards DR, Pennington CJ, Guttery DS, Shaw JA, Walker RA, Pringle JH, Jones JL.

Breast Cancer Res. 2009;11(2):R24. doi: 10.1186/bcr2251. Epub 2009 Apr 30.

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