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Items: 1 to 50 of 244

1.

Low-Fat Diet Designed for Weight Loss But Not Weight Maintenance Improves Nitric Oxide-Dependent Arteriolar Vasodilation in Obese Adults.

Mahmoud AM, Hwang CL, Szczurek MR, Bian JT, Ranieri C, Gutterman DD, Phillips SA.

Nutrients. 2019 Jun 14;11(6). pii: E1339. doi: 10.3390/nu11061339.

2.

The Relationship Between Blood Flow and Motor Unit Firing Rates in Response to Fatiguing Exercise Post-stroke.

Murphy S, Durand M, Negro F, Farina D, Hunter S, Schmit B, Gutterman D, Hyngstrom A.

Front Physiol. 2019 May 10;10:545. doi: 10.3389/fphys.2019.00545. eCollection 2019.

3.

Mitochondrial Oxidative Phosphorylation defect in the Heart of Subjects with Coronary Artery Disease.

Ait-Aissa K, Blaszak SC, Beutner G, Tsaih SW, Morgan G, Santos JH, Flister MJ, Joyce DL, Camara AKS, Gutterman DD, Donato AJ, Porter GA Jr, Beyer AM.

Sci Rep. 2019 May 20;9(1):7623. doi: 10.1038/s41598-019-43761-y.

4.

Cannabidiol (CBD) reduces anxiety-related behavior in mice via an FMRP-independent mechanism.

Zieba J, Sinclair D, Sebree T, Bonn-Miller M, Gutterman D, Siegel S, Karl T.

Pharmacol Biochem Behav. 2019 Jun;181:93-100. doi: 10.1016/j.pbb.2019.05.002. Epub 2019 May 4.

PMID:
31063743
5.

Risk-Based Disease Surveillance: The Promise of Early Atrial Fibrillation Identification.

Berger MG, Gutterman D.

Chest. 2019 Mar;155(3):458-459. doi: 10.1016/j.chest.2018.09.005. No abstract available.

PMID:
30846062
6.

Detection of Left Ventricular Hypertrophy Using Bayesian Additive Regression Trees: The MESA.

Sparapani R, Dabbouseh NM, Gutterman D, Zhang J, Chen H, Bluemke DA, Lima JAC, Burke GL, Soliman EZ.

J Am Heart Assoc. 2019 Mar 5;8(5):e009959. doi: 10.1161/JAHA.118.009959. Erratum in: J Am Heart Assoc. 2019 May 7;8(9):e002294.

7.

Two weeks of ischemic conditioning improves walking speed and reduces neuromuscular fatigability in chronic stroke survivors.

Durand MJ, Boerger TF, Nguyen JN, Alqahtani SZ, Wright MT, Schmit BD, Gutterman DD, Hyngstrom AS.

J Appl Physiol (1985). 2019 Mar 1;126(3):755-763. doi: 10.1152/japplphysiol.00772.2018. Epub 2019 Jan 17.

PMID:
30653420
8.

Cardiac contractility modulation improves long-term survival and hospitalizations in heart failure with reduced ejection fraction.

Anker SD, Borggrefe M, Neuser H, Ohlow MA, Röger S, Goette A, Remppis BA, Kuck KH, Najarian KB, Gutterman DD, Rousso B, Burkhoff D, Hasenfuss G.

Eur J Heart Fail. 2019 Jan 16. doi: 10.1002/ejhf.1374. [Epub ahead of print]

PMID:
30652394
9.

Cardiac contractility modulation: mechanisms of action in heart failure with reduced ejection fraction and beyond.

Tschöpe C, Kherad B, Klein O, Lipp A, Blaschke F, Gutterman D, Burkhoff D, Hamdani N, Spillmann F, Van Linthout S.

Eur J Heart Fail. 2019 Jan;21(1):14-22. doi: 10.1002/ejhf.1349. Epub 2018 Nov 28. Review.

PMID:
30485591
10.

Visualization and Quantification of Mitochondrial Structure in the Endothelium of Intact Arteries.

Durand MJ, Ait-Aissa K, Levchenko V, Staruschenko A, Gutterman DD, Beyer AM.

Cardiovasc Res. 2018 Nov 22. doi: 10.1093/cvr/cvy294. [Epub ahead of print]

PMID:
30476208
11.

Cardiac contractility modulation treatment in patients with symptomatic heart failure despite optimal medical therapy and cardiac resynchronization therapy (CRT).

Kuschyk J, Nägele H, Heinz-Kuck K, Butter C, Lawo T, Wietholt D, Roeger S, Gutterman D, Burkhoff D, Rousso B, Borggrefe M.

Int J Cardiol. 2019 Feb 15;277:173-177. doi: 10.1016/j.ijcard.2018.10.086. Epub 2018 Oct 29.

PMID:
30409733
12.

Lysophosphatidic acid acts on LPA1 receptor to increase H2 O2 during flow-induced dilation in human adipose arterioles.

Chabowski DS, Kadlec AO, Ait-Aissa K, Hockenberry JC, Pearson PJ, Beyer AM, Gutterman DD.

Br J Pharmacol. 2018 Nov;175(22):4266-4280. doi: 10.1111/bph.14492. Epub 2018 Oct 11.

PMID:
30153326
13.

Physiological Consequences of Coronary Arteriolar Dysfunction and Its Influence on Cardiovascular Disease.

Allaqaband H, Gutterman DD, Kadlec AO.

Physiology (Bethesda). 2018 Sep 1;33(5):338-347. doi: 10.1152/physiol.00019.2018. Review.

PMID:
30109826
14.

A Randomized Controlled Trial to Evaluate the Safety and Efficacy of Cardiac Contractility Modulation.

Abraham WT, Kuck KH, Goldsmith RL, Lindenfeld J, Reddy VY, Carson PE, Mann DL, Saville B, Parise H, Chan R, Wiegn P, Hastings JL, Kaplan AJ, Edelmann F, Luthje L, Kahwash R, Tomassoni GF, Gutterman DD, Stagg A, Burkhoff D, Hasenfuß G.

JACC Heart Fail. 2018 Oct;6(10):874-883. doi: 10.1016/j.jchf.2018.04.010. Epub 2018 May 10.

15.

YAP1-TEAD1 signaling controls angiogenesis and mitochondrial biogenesis through PGC1α.

Mammoto A, Muyleart M, Kadlec A, Gutterman D, Mammoto T.

Microvasc Res. 2018 Sep;119:73-83. doi: 10.1016/j.mvr.2018.04.003. Epub 2018 Apr 20.

PMID:
29680477
16.

Regular Aerobic, Resistance, and Cross-Training Exercise Prevents Reduced Vascular Function Following a High Sugar or High Fat Mixed Meal in Young Healthy Adults.

Das EK, Lai PY, Robinson AT, Pleuss J, Ali MM, Haus JM, Gutterman DD, Phillips SA.

Front Physiol. 2018 Mar 8;9:183. doi: 10.3389/fphys.2018.00183. eCollection 2018.

17.

Ischemic conditioning increases strength and volitional activation of paretic muscle in chronic stroke: a pilot study.

Hyngstrom AS, Murphy SA, Nguyen J, Schmit BD, Negro F, Gutterman DD, Durand MJ.

J Appl Physiol (1985). 2018 May 1;124(5):1140-1147. doi: 10.1152/japplphysiol.01072.2017. Epub 2018 Feb 8.

18.

Telomerase reverse transcriptase protects against angiotensin II-induced microvascular endothelial dysfunction.

Ait-Aissa K, Kadlec AO, Hockenberry J, Gutterman DD, Beyer AM.

Am J Physiol Heart Circ Physiol. 2018 May 1;314(5):H1053-H1060. doi: 10.1152/ajpheart.00472.2017. Epub 2017 Dec 22.

19.

The Yin and Yang of endothelium-derived vasodilator factors.

Kadlec AO, Gutterman DD.

Am J Physiol Heart Circ Physiol. 2018 May 1;314(5):H892-H894. doi: 10.1152/ajpheart.00019.2018. Epub 2018 Jan 19. No abstract available.

20.

Shaker-related voltage-gated K+ channel expression and vasomotor function in human coronary resistance arteries.

Nishijima Y, Korishettar A, Chabowski DS, Cao S, Zheng X, Gutterman DD, Zhang DX.

Microcirculation. 2018 Jan;25(1). doi: 10.1111/micc.12431.

21.

Microvascular Adaptations to Exercise: Protective Effect of PGC-1 Alpha.

Kadlec AO, Barnes C, Durand MJ, Gutterman DD.

Am J Hypertens. 2018 Jan 12;31(2):240-246. doi: 10.1093/ajh/hpx162.

22.

Clinical effects of long-term cardiac contractility modulation (CCM) in subjects with heart failure caused by left ventricular systolic dysfunction.

Müller D, Remppis A, Schauerte P, Schmidt-Schweda S, Burkhoff D, Rousso B, Gutterman D, Senges J, Hindricks G, Kuck KH.

Clin Res Cardiol. 2017 Nov;106(11):893-904. doi: 10.1007/s00392-017-1135-9. Epub 2017 Jul 6.

23.

Why publish in the American Journal of Physiology-Heart and Circulatory Physiology?

Zucker IH, Lindsey ML, Delmar M, De Windt LJ, Des Rosiers C, Diz DI, Hester RL, Jones SP, Kanagy NL, Kitakaze M, Liao R, Lopaschuk GD, Patel KP, Recchia FA, Sadoshima J, Shah AM, Ungvari Z, Benjamin IJ, Blaustein MP, Charkoudian N, Efimov IR, Gutterman D, Kass DA, Liao Y, O'Leary DS, Ripplinger CM, Wolin MS.

Am J Physiol Heart Circ Physiol. 2017 Aug 1;313(2):H221-H223. doi: 10.1152/ajpheart.00329.2017. Epub 2017 Jun 16. No abstract available.

24.

PGC-1α (Peroxisome Proliferator-Activated Receptor γ Coactivator 1-α) Overexpression in Coronary Artery Disease Recruits NO and Hydrogen Peroxide During Flow-Mediated Dilation and Protects Against Increased Intraluminal Pressure.

Kadlec AO, Chabowski DS, Ait-Aissa K, Hockenberry JC, Otterson MF, Durand MJ, Freed JK, Beyer AM, Gutterman DD.

Hypertension. 2017 Jul;70(1):166-173. doi: 10.1161/HYPERTENSIONAHA.117.09289. Epub 2017 May 22.

25.

Communication Is Key: Mechanisms of Intercellular Signaling in Vasodilation.

Freed JK, Gutterman DD.

J Cardiovasc Pharmacol. 2017 May;69(5):264-272. doi: 10.1097/FJC.0000000000000463. Review.

26.

Roles of NADPH oxidase and mitochondria in flow-induced vasodilation of human adipose arterioles: ROS-induced ROS release in coronary artery disease.

Zinkevich NS, Fancher IS, Gutterman DD, Phillips SA.

Microcirculation. 2017 Aug;24(6). doi: 10.1111/micc.12380.

27.

Regenerative Angiogenesis: Quality Over Quantity.

Durand MJ, Ait-Aissa K, Gutterman DD.

Circ Res. 2017 Apr 28;120(9):1379-1380. doi: 10.1161/CIRCRESAHA.117.310918. No abstract available.

PMID:
28450357
28.

Adapt or Perish: Updating the Predoctoral Training Model.

Chabowski D, Kadlec A, Dellostritto D, Gutterman D.

Circ Res. 2017 Mar 31;120(7):1081-1083. doi: 10.1161/CIRCRESAHA.116.310048. No abstract available.

29.

Mitochondria-regulated formation of endothelium-derived extracellular vesicles shifts the mediator of flow-induced vasodilation.

Freed JK, Durand MJ, Hoffmann BR, Densmore JC, Greene AS, Gutterman DD.

Am J Physiol Heart Circ Physiol. 2017 May 1;312(5):H1096-H1104. doi: 10.1152/ajpheart.00680.2016. Epub 2017 Feb 17.

30.

5,6-δ-DHTL, a stable metabolite of arachidonic acid, is a potential EDHF that mediates microvascular dilation.

Levi-Rosenzvig R, Beyer AM, Hockenberry J, Ben-Shushan RS, Chuyun D, Atiya S, Tamir S, Gutterman DD, Szuchman-Sapir A.

Free Radic Biol Med. 2017 Feb;103:87-94. doi: 10.1016/j.freeradbiomed.2016.12.022. Epub 2016 Dec 19.

PMID:
28007573
31.

Transition in the mechanism of flow-mediated dilation with aging and development of coronary artery disease.

Beyer AM, Zinkevich N, Miller B, Liu Y, Wittenburg AL, Mitchell M, Galdieri R, Sorokin A, Gutterman DD.

Basic Res Cardiol. 2017 Jan;112(1):5. Epub 2016 Dec 19.

PMID:
27995364
32.

Mechanisms of Vascular Dysfunction in COPD and Effects of a Novel Soluble Epoxide Hydrolase Inhibitor in Smokers.

Yang L, Cheriyan J, Gutterman DD, Mayer RJ, Ament Z, Griffin JL, Lazaar AL, Newby DE, Tal-Singer R, Wilkinson IB.

Chest. 2017 Mar;151(3):555-563. doi: 10.1016/j.chest.2016.10.058. Epub 2016 Nov 21.

33.

Contribution of KV1.5 Channel to Hydrogen Peroxide-Induced Human Arteriolar Dilation and Its Modulation by Coronary Artery Disease.

Nishijima Y, Cao S, Chabowski DS, Korishettar A, Ge A, Zheng X, Sparapani R, Gutterman DD, Zhang DX.

Circ Res. 2017 Feb 17;120(4):658-669. doi: 10.1161/CIRCRESAHA.116.309491. Epub 2016 Nov 21.

34.

Hypertension during Weight Lifting Reduces Flow-Mediated Dilation in Nonathletes.

Buchanan CE, Kadlec AO, Hoch AZ, Gutterman DD, Durand MJ.

Med Sci Sports Exerc. 2017 Apr;49(4):669-675. doi: 10.1249/MSS.0000000000001150.

35.

Shock associated with endothelial dysfunction in omental microvessels.

Somberg LB, Gutterman DD, Miura H, Nirula R, Hatoum OA.

Eur J Clin Invest. 2017 Jan;47(1):30-37. doi: 10.1111/eci.12697. Epub 2016 Dec 7.

PMID:
27809354
36.

Cardiac contractility modulation: a novel approach for the treatment of heart failure.

Abi-Samra F, Gutterman D.

Heart Fail Rev. 2016 Nov;21(6):645-660. Review.

37.

Heart Failure: a Major Cardiovascular Complication of Diabetes Mellitus.

Bahtiyar G, Gutterman D, Lebovitz H.

Curr Diab Rep. 2016 Nov;16(11):116. Review.

38.

Cardiac contractility modulation in heart failure patients: Randomized comparison of signal delivery through one vs. two ventricular leads.

Röger S, Said S, Kloppe A, Lawo T, Emig U, Rousso B, Gutterman D, Borggrefe M, Kuschyk J.

J Cardiol. 2017 Jan;69(1):326-332. doi: 10.1016/j.jjcc.2016.06.015. Epub 2016 Aug 30.

39.

Role of PGC-1α in Vascular Regulation: Implications for Atherosclerosis.

Kadlec AO, Chabowski DS, Ait-Aissa K, Gutterman DD.

Arterioscler Thromb Vasc Biol. 2016 Aug;36(8):1467-74. doi: 10.1161/ATVBAHA.116.307123. Epub 2016 Jun 16. Review.

40.

Vascular Actions of Angiotensin 1-7 in the Human Microcirculation: Novel Role for Telomerase.

Durand MJ, Zinkevich NS, Riedel M, Gutterman DD, Nasci VL, Salato VK, Hijjawi JB, Reuben CF, North PE, Beyer AM.

Arterioscler Thromb Vasc Biol. 2016 Jun;36(6):1254-62. doi: 10.1161/ATVBAHA.116.307518. Epub 2016 Apr 14.

41.

Mitochondrial signaling in the vascular endothelium: beyond reactive oxygen species.

Kadlec AO, Beyer AM, Ait-Aissa K, Gutterman DD.

Basic Res Cardiol. 2016 May;111(3):26. doi: 10.1007/s00395-016-0546-5. Epub 2016 Mar 18. Review.

PMID:
26992928
42.

The Human Microcirculation: Regulation of Flow and Beyond.

Gutterman DD, Chabowski DS, Kadlec AO, Durand MJ, Freed JK, Ait-Aissa K, Beyer AM.

Circ Res. 2016 Jan 8;118(1):157-72. doi: 10.1161/CIRCRESAHA.115.305364. Review.

43.

Improvement of long-term survival by cardiac contractility modulation in heart failure patients: A case-control study.

Liu M, Fang F, Luo XX, Shlomo BH, Burkhoff D, Chan JY, Chan CP, Cheung L, Rousso B, Gutterman D, Yu CM.

Int J Cardiol. 2016 Mar 1;206:122-6. doi: 10.1016/j.ijcard.2016.01.071. Epub 2016 Jan 6.

PMID:
26788686
44.

Critical Role for Telomerase in the Mechanism of Flow-Mediated Dilation in the Human Microcirculation.

Beyer AM, Freed JK, Durand MJ, Riedel M, Ait-Aissa K, Green P, Hockenberry JC, Morgan RG, Donato AJ, Peleg R, Gasparri M, Rokkas CK, Santos JH, Priel E, Gutterman DD.

Circ Res. 2016 Mar 4;118(5):856-66. doi: 10.1161/CIRCRESAHA.115.307918. Epub 2015 Dec 23.

45.

Cardiac contractility modulation signals improve exercise intolerance and maladaptive regulation of cardiac key proteins for systolic and diastolic function in HFpEF.

Tschöpe C, Van Linthout S, Spillmann F, Klein O, Biewener S, Remppis A, Gutterman D, Linke WA, Pieske B, Hamdani N, Roser M.

Int J Cardiol. 2016 Jan 15;203:1061-6. doi: 10.1016/j.ijcard.2015.10.208. Epub 2015 Oct 27. No abstract available.

PMID:
26638055
46.

Impaired Hyperemic Response to Exercise Post Stroke.

Durand MJ, Murphy SA, Schaefer KK, Hunter SK, Schmit BD, Gutterman DD, Hyngstrom AS.

PLoS One. 2015 Dec 2;10(12):e0144023. doi: 10.1371/journal.pone.0144023. eCollection 2015.

47.

Endothelium-Derived Hyperpolarization and Coronary Vasodilation: Diverse and Integrated Roles of Epoxyeicosatrienoic Acids, Hydrogen Peroxide, and Gap Junctions.

Ellinsworth DC, Sandow SL, Shukla N, Liu Y, Jeremy JY, Gutterman DD.

Microcirculation. 2016 Jan;23(1):15-32. doi: 10.1111/micc.12255. Review.

48.

Unveiling the Mechanism of Coronary Metabolic Vasodilation: Voltage-Gated Potassium Channels and Hydrogen Peroxide.

Chabowski D, Gutterman D.

Circ Res. 2015 Sep 11;117(7):589-91. doi: 10.1161/CIRCRESAHA.115.307281. No abstract available.

49.

Treatment of Patients with Obese Type 2 Diabetes with Tantalus-DIAMOND® Gastric Electrical Stimulation: Normal Triglycerides Predict Durable Effects for at Least 3 Years.

Lebovitz HE, Ludvik B, Yaniv I, Schwartz T, Zelewski M, Gutterman DD; Metacure Investigators.

Horm Metab Res. 2015 Jun;47(6):456-62. doi: 10.1055/s-0035-1548944. Epub 2015 Apr 16.

PMID:
25993254
50.

Acute exertion elicits a H2O2-dependent vasodilator mechanism in the microvasculature of exercise-trained but not sedentary adults.

Durand MJ, Dharmashankar K, Bian JT, Das E, Vidovich M, Gutterman DD, Phillips SA.

Hypertension. 2015 Jan;65(1):140-5. doi: 10.1161/HYPERTENSIONAHA.114.04540. Epub 2014 Nov 3.

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