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Items: 1 to 50 of 68

1.

Effects of the Tobacco Carcinogens N'-Nitrosonornicotine and Dibenzo[a,l]pyrene Individually and in Combination on DNA Damage in Human Oral Leukoplakia and on Mutagenicity and Mutation Profiles in lacI Mouse Tongue.

Guttenplan JB, Chen KM, Sun YW, Shalaby NAE, Kosinska W, Desai D, Gowda K, Amin S, El-Bayoumy K.

Chem Res Toxicol. 2019 Sep 16;32(9):1893-1899. doi: 10.1021/acs.chemrestox.9b00257. Epub 2019 Sep 3.

PMID:
31433626
2.

E-cigarette Aerosol Condensate Enhances Metabolism of Benzo(a)pyrene to Genotoxic Products, and Induces CYP1A1 and CYP1B1, Likely by Activation of the Aryl Hydrocarbon Receptor.

Sun YW, Kosinska W, Guttenplan JB.

Int J Environ Res Public Health. 2019 Jul 11;16(14). pii: E2468. doi: 10.3390/ijerph16142468.

3.

Effects of Black Raspberry on Dibenzo[a,l]Pyrene Diol Epoxide Induced DNA Adducts, Mutagenesis, and Tumorigenesis in the Mouse Oral Cavity.

Chen KM, Guttenplan JB, Sun YW, Cooper T, Shalaby NAE, Kosinska W, Benitez G, Aliaga C, Zhu J, Liao J, Gowda K, Amin S, Stoner G, El-Bayoumy K.

Cancer Prev Res (Phila). 2018 Mar;11(3):157-164. doi: 10.1158/1940-6207.CAPR-17-0278. Epub 2017 Nov 20.

4.

Effects of Black Raspberry Extract and Berry Compounds on Repair of DNA Damage and Mutagenesis Induced by Chemical and Physical Agents in Human Oral Leukoplakia and Rat Oral Fibroblasts.

Guttenplan JB, Chen KM, Sun YW, Lajara B, Shalaby NAE, Kosinska W, Benitez G, Gowda K, Amin S, Stoner G, El-Bayoumy K.

Chem Res Toxicol. 2017 Dec 18;30(12):2159-2164. doi: 10.1021/acs.chemrestox.7b00242. Epub 2017 Nov 15.

PMID:
29068672
5.

Carcinogenesis of the Oral Cavity: Environmental Causes and Potential Prevention by Black Raspberry.

El-Bayoumy K, Chen KM, Zhang SM, Sun YW, Amin S, Stoner G, Guttenplan JB.

Chem Res Toxicol. 2017 Jan 17;30(1):126-144. doi: 10.1021/acs.chemrestox.6b00306. Epub 2016 Dec 2.

PMID:
28092946
6.

Effects of Black Raspberry Extract and Protocatechuic Acid on Carcinogen-DNA Adducts and Mutagenesis, and Oxidative Stress in Rat and Human Oral Cells.

Guttenplan JB, Chen KM, Sun YW, Kosinska W, Zhou Y, Kim SA, Sung Y, Gowda K, Amin S, Stoner GD, El-Bayoumy K.

Cancer Prev Res (Phila). 2016 Aug;9(8):704-12. doi: 10.1158/1940-6207.CAPR-16-0003. Epub 2016 Jun 7.

7.

Mutagenicity of furan in female Big Blue B6C3F1 mice.

Terrell AN, Huynh M, Grill AE, Kovi RC, O'Sullivan MG, Guttenplan JB, Ho YY, Peterson LA.

Mutat Res Genet Toxicol Environ Mutagen. 2014 Aug;770:46-54. doi: 10.1016/j.mrgentox.2014.04.024. Epub 2014 Jun 2.

8.

p53 modulates Hsp90 ATPase activity and regulates aryl hydrocarbon receptor signaling.

Kochhar A, Kopelovich L, Sue E, Guttenplan JB, Herbert BS, Dannenberg AJ, Subbaramaiah K.

Cancer Prev Res (Phila). 2014 Jun;7(6):596-606. doi: 10.1158/1940-6207.CAPR-14-0051. Epub 2014 Apr 15.

9.

Mechanisms of oral carcinogenesis induced by dibenzo[a,l]pyrene: an environmental pollutant and a tobacco smoke constituent.

Chen KM, Guttenplan JB, Zhang SM, Aliaga C, Cooper TK, Sun YW, DelTondo J, Kosinska W, Sharma AK, Jiang K, Bruggeman R, Ahn K, Amin S, El-Bayoumy K.

Int J Cancer. 2013 Sep 15;133(6):1300-9. doi: 10.1002/ijc.28152. Epub 2013 Apr 22.

10.

Mechanisms underlying the varied mammary carcinogenicity of the environmental pollutant 6-nitrochrysene and its metabolites (-)-[R,R]- and (+)-[S,S]-1,2-dihydroxy-1,2-dihydro-6-nitrochrysene in the rat.

Sun YW, Guttenplan JB, Cooper T, Krzeminski J, Aliaga C, Boyiri T, Kosinska W, Zhao ZL, Chen KM, Berg A, Amin S, El-Bayoumy K.

Chem Res Toxicol. 2013 Apr 15;26(4):547-54. doi: 10.1021/tx300478z. Epub 2013 Mar 28.

11.

Carnosol, a constituent of Zyflamend, inhibits aryl hydrocarbon receptor-mediated activation of CYP1A1 and CYP1B1 transcription and mutagenesis.

Mohebati A, Guttenplan JB, Kochhar A, Zhao ZL, Kosinska W, Subbaramaiah K, Dannenberg AJ.

Cancer Prev Res (Phila). 2012 Apr;5(4):593-602. doi: 10.1158/1940-6207.CAPR-12-0002. Epub 2012 Feb 28.

12.

Tissue-specific mutagenesis by N-butyl-N-(4-hydroxybutyl)nitrosamine as the basis for urothelial carcinogenesis.

He Z, Kosinska W, Zhao ZL, Wu XR, Guttenplan JB.

Mutat Res. 2012 Feb 18;742(1-2):92-5. doi: 10.1016/j.mrgentox.2011.11.015. Epub 2011 Dec 4.

PMID:
22155125
13.

Mutagenesis and carcinogenesis induced by dibenzo[a,l]pyrene in the mouse oral cavity: a potential new model for oral cancer.

Guttenplan JB, Kosinska W, Zhao ZL, Chen KM, Aliaga C, DelTondo J, Cooper T, Sun YW, Zhang SM, Jiang K, Bruggeman R, Sharma AK, Amin S, Ahn K, El-Bayoumy K.

Int J Cancer. 2012 Jun 15;130(12):2783-90. doi: 10.1002/ijc.26344. Epub 2011 Nov 19.

14.

Concentration dependent effects of tobacco particulates from different types of cigarettes on expression of drug metabolizing proteins, and benzo(a)pyrene metabolism in primary normal human oral epithelial cells.

Sacks PG, Zhao ZL, Kosinska W, Fleisher KE, Gordon T, Guttenplan JB.

Food Chem Toxicol. 2011 Sep;49(9):2348-55. doi: 10.1016/j.fct.2011.06.037. Epub 2011 Jun 21.

15.

Effects of potential dietary inhibitors of endogenous DNA damage on mutagenesis and lipid peroxidation in lacZ mice.

Kosinska W, Khmelnitsky M, Kim JH, Zhao ZL, Guttenplan JB.

Environ Mol Mutagen. 2011 Jul;52(6):502-9. doi: 10.1002/em.20648. Epub 2011 Apr 27.

PMID:
21538553
17.

UVR exposure sensitizes keratinocytes to DNA adduct formation.

Nair S, Kekatpure VD, Judson BL, Rifkind AB, Granstein RD, Boyle JO, Subbaramaiah K, Guttenplan JB, Dannenberg AJ.

Cancer Prev Res (Phila). 2009 Oct;2(10):895-902. doi: 10.1158/1940-6207.CAPR-09-0125. Epub 2009 Sep 29.

18.

Heat shock protein 90 inhibitors suppress aryl hydrocarbon receptor-mediated activation of CYP1A1 and CYP1B1 transcription and DNA adduct formation.

Hughes D, Guttenplan JB, Marcus CB, Subbaramaiah K, Dannenberg AJ.

Cancer Prev Res (Phila). 2008 Nov;1(6):485-93. doi: 10.1158/1940-6207.CAPR-08-0149.

19.

Comparative mutational profiles of the environmental mammary carcinogen, 6-nitrochrysene and its metabolites in a lacI mammary epithelial cell line.

Guttenplan JB, Zhao ZL, Kosinska W, Norman RG, Krzeminski J, Sun YW, Amin S, El-Bayoumy K.

Carcinogenesis. 2007 Nov;28(11):2391-7. Epub 2007 Jun 29.

PMID:
17602172
20.

Mutagenic activity of 4-hydroxyestradiol, but not 2-hydroxyestradiol, in BB rat2 embryonic cells, and the mutational spectrum of 4-hydroxyestradiol.

Zhao Z, Kosinska W, Khmelnitsky M, Cavalieri EL, Rogan EG, Chakravarti D, Sacks PG, Guttenplan JB.

Chem Res Toxicol. 2006 Mar;19(3):475-9.

PMID:
16544955
21.

Mutational spectrum of bleomycin in lacZ mouse kidney: a possible model for mutational spectrum of reactive oxygen species.

Guttenplan JB, Khmelnitsky M, Haesevoets R, Kosinska W.

Mutat Res. 2004 Oct 4;554(1-2):185-92.

PMID:
15450417
23.

Comparative mutagenicities of bleomycin and ferric-nitrilotriacetate in lacZ mice.

Kosinska W, Pelle E, von Pressentin Md, Chen M, Guttenplan JB.

Cancer Lett. 2002 Dec 10;187(1-2):41-6. Erratum in: Cancer Lett. 2004 Mar 18;205(2):229.

PMID:
12359349
24.

Effects of 1,4-phenylenebis(methylene)selenocyanate (p-XSC) and vitamin E on 4-nitroquinoline-N-oxide (4-NQO)-induced mutagenesis in lacZ mouse upper aerodigestive tissue.

Guttenplan JB, Kosinska W, von Pressentin Md, Rosa J, El-Bayoumy K.

Mutat Res. 2002 Jun 27;518(1):85-93. Erratum in: Mutat Res. 2002 Nov 26;521(1-2):209..

PMID:
12063070
25.

Effects of a lycopene-rich diet on spontaneous and benzo[a]pyrene-induced mutagenesis in prostate, colon and lungs of the lacZ mouse.

Guttenplan JB, Chen M, Kosinska W, Thompson S, Zhao Z, Cohen LA.

Cancer Lett. 2001 Mar 10;164(1):1-6.

PMID:
11166909
27.
28.

Mutagenesis induced by oral carcinogens in lacZ mouse (MutaMouse) tongue and other oral tissues.

von Pressentin MM, Kosinska W, Guttenplan JB.

Carcinogenesis. 1999 Nov;20(11):2167-70.

PMID:
10545421
30.

1,N2-propanodeoxyguanosine adducts: potential new biomarkers of smoking-induced DNA damage in human oral tissue.

Nath RG, Ocando JE, Guttenplan JB, Chung FL.

Cancer Res. 1998 Feb 15;58(4):581-4.

31.

Unexpected genetic toxicity to rodents of the N',N'-dimethyl analogues of MNU and ENU.

Tinwell H, Paton D, Guttenplan JB, Ashby J.

Environ Mol Mutagen. 1996;27(3):202-10.

PMID:
8625956
32.

2,3-epoxy-4-hydroxynonanal as a potential tumor-initiating agent of lipid peroxidation.

Chung FL, Chen HJ, Guttenplan JB, Nishikawa A, Hard GC.

Carcinogenesis. 1993 Oct;14(10):2073-7.

PMID:
8222056
37.
39.
41.
42.

N-nitrosamines: bacterial mutagenesis and in vitro metabolism.

Guttenplan JB.

Mutat Res. 1987 Sep;186(2):81-134. Review.

PMID:
3306361
43.
44.

Mutagenic activity in smokeless tobacco products sold in the USA.

Guttenplan JB.

Carcinogenesis. 1987 May;8(5):741-3.

PMID:
3581433
45.
48.

Uptake and metabolism of cisplatin by rat kidney.

Safirstein R, Miller P, Guttenplan JB.

Kidney Int. 1984 May;25(5):753-8.

50.

Inhibition of amino acid transport by cis-diamminedichloroplatinum(II) derivatives in L1210 murine leukemia cells.

Scanlon KJ, Safirstein RL, Thies H, Gross RB, Waxman S, Guttenplan JB.

Cancer Res. 1983 Sep;43(9):4211-5.

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