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Items: 42

1.

GMP Production and Scale-Up of Adherent Neural Stem Cells with a Quantum Cell Expansion System.

Tirughana R, Metz MZ, Li Z, Hall C, Hsu D, Beltzer J, Annala AJ, Oganesyan D, Gutova M, Aboody KS.

Mol Ther Methods Clin Dev. 2018 Jul 7;10:48-56. doi: 10.1016/j.omtm.2018.05.006. eCollection 2018 Sep 21.

2.

Early Changes in Tumor Perfusion from T1-Weighted Dynamic Contrast-Enhanced MRI following Neural Stem Cell-Mediated Therapy of Recurrent High-Grade Glioma Correlate with Overall Survival.

Sahoo P, Frankel P, Ressler J, Gutova M, Annala AJ, Badie B, Portnow J, Aboody KS, D'Apuzzo M, Rockne RC.

Stem Cells Int. 2018 Mar 14;2018:5312426. doi: 10.1155/2018/5312426. eCollection 2018.

3.

Human Neural Stem Cell Biodistribution and Predicted Tumor Coverage by a Diffusible Therapeutic in a Mouse Glioma Model.

Barish ME, Herrmann K, Tang Y, Argalian Herculian S, Metz M, Aramburo S, Tirughana R, Gutova M, Annala A, Moats RA, Goldstein L, Rockne RC, Gutierrez J, Brown CE, Ghoda L, Aboody KS.

Stem Cells Transl Med. 2017 Jun;6(6):1522-1532. doi: 10.1002/sctm.16-0397. Epub 2017 May 8.

4.

Optimization of a Neural Stem-Cell-Mediated Carboxylesterase/Irinotecan Gene Therapy for Metastatic Neuroblastoma.

Gutova M, Goldstein L, Metz M, Hovsepyan A, Tsurkan LG, Tirughana R, Tsaturyan L, Annala AJ, Synold TW, Wan Z, Seeger R, Anderson C, Moats RA, Potter PM, Aboody KS.

Mol Ther Oncolytics. 2016 Dec 14;4:67-76. doi: 10.1016/j.omto.2016.11.004. eCollection 2017 Mar 17.

5.

Neural Stem Cell-Based Anticancer Gene Therapy: A First-in-Human Study in Recurrent High-Grade Glioma Patients.

Portnow J, Synold TW, Badie B, Tirughana R, Lacey SF, D'Apuzzo M, Metz MZ, Najbauer J, Bedell V, Vo T, Gutova M, Frankel P, Chen M, Aboody KS.

Clin Cancer Res. 2017 Jun 15;23(12):2951-2960. doi: 10.1158/1078-0432.CCR-16-1518. Epub 2016 Dec 15.

6.

L-MYC Expression Maintains Self-Renewal and Prolongs Multipotency of Primary Human Neural Stem Cells.

Li Z, Oganesyan D, Mooney R, Rong X, Christensen MJ, Shahmanyan D, Perrigue PM, Benetatos J, Tsaturyan L, Aramburo S, Annala AJ, Lu Y, Najbauer J, Wu X, Barish ME, Brody DL, Aboody KS, Gutova M.

Stem Cell Reports. 2016 Sep 13;7(3):483-495. doi: 10.1016/j.stemcr.2016.07.013. Epub 2016 Aug 18.

7.

The histone demethylase jumonji coordinates cellular senescence including secretion of neural stem cell-attracting cytokines.

Perrigue PM, Silva ME, Warden CD, Feng NL, Reid MA, Mota DJ, Joseph LP, Tian YI, Glackin CA, Gutova M, Najbauer J, Aboody KS, Barish ME.

Mol Cancer Res. 2015 Apr;13(4):636-50. doi: 10.1158/1541-7786.MCR-13-0268. Epub 2015 Feb 4.

8.

Analysis of glioblastoma tumor coverage by oncolytic virus-loaded neural stem cells using MRI-based tracking and histological reconstruction.

Morshed RA, Gutova M, Juliano J, Barish ME, Hawkins-Daarud A, Oganesyan D, Vazgen K, Yang T, Annala A, Ahmed AU, Aboody KS, Swanson KR, Moats RA, Lesniak MS.

Cancer Gene Ther. 2015 Jan;22(1):55-61. doi: 10.1038/cgt.2014.72. Epub 2014 Dec 19.

9.

Neural stem cells improve intracranial nanoparticle retention and tumor-selective distribution.

Mooney R, Weng Y, Tirughana-Sambandan R, Valenzuela V, Aramburo S, Garcia E, Li Z, Gutova M, Annala AJ, Berlin JM, Aboody KS.

Future Oncol. 2014 Feb;10(3):401-15. doi: 10.2217/fon.13.217.

10.

Neural stem cell-mediated delivery of irinotecan-activating carboxylesterases to glioma: implications for clinical use.

Metz MZ, Gutova M, Lacey SF, Abramyants Y, Vo T, Gilchrist M, Tirughana R, Ghoda LY, Barish ME, Brown CE, Najbauer J, Potter PM, Portnow J, Synold TW, Aboody KS.

Stem Cells Transl Med. 2013 Dec;2(12):983-92. doi: 10.5966/sctm.2012-0177. Epub 2013 Oct 28.

11.

Magnetic resonance imaging tracking of ferumoxytol-labeled human neural stem cells: studies leading to clinical use.

Gutova M, Frank JA, D'Apuzzo M, Khankaldyyan V, Gilchrist MM, Annala AJ, Metz MZ, Abramyants Y, Herrmann KA, Ghoda LY, Najbauer J, Brown CE, Blanchard MS, Lesniak MS, Kim SU, Barish ME, Aboody KS, Moats RA.

Stem Cells Transl Med. 2013 Oct;2(10):766-75. doi: 10.5966/sctm.2013-0049. Epub 2013 Sep 6.

12.

Intranasal delivery of mesenchymal stem cells significantly extends survival of irradiated mice with experimental brain tumors.

Balyasnikova IV, Prasol MS, Ferguson SD, Han Y, Ahmed AU, Gutova M, Tobias AL, Mustafi D, Rincón E, Zhang L, Aboody KS, Lesniak MS.

Mol Ther. 2014 Jan;22(1):140-8. doi: 10.1038/mt.2013.199. Epub 2013 Sep 3.

13.

Neural stem cell-mediated enzyme/prodrug therapy for glioma: preclinical studies.

Aboody KS, Najbauer J, Metz MZ, D'Apuzzo M, Gutova M, Annala AJ, Synold TW, Couture LA, Blanchard S, Moats RA, Garcia E, Aramburo S, Valenzuela VV, Frank RT, Barish ME, Brown CE, Kim SU, Badie B, Portnow J.

Sci Transl Med. 2013 May 8;5(184):184ra59. doi: 10.1126/scitranslmed.3005365.

14.

Cellular host responses to gliomas.

Najbauer J, Huszthy PC, Barish ME, Garcia E, Metz MZ, Myers SM, Gutova M, Frank RT, Miletic H, Kendall SE, Glackin CA, Bjerkvig R, Aboody KS.

PLoS One. 2012;7(4):e35150. doi: 10.1371/journal.pone.0035150. Epub 2012 Apr 23.

15.

Neural stem cell-mediated CE/CPT-11 enzyme/prodrug therapy in transgenic mouse model of intracerebellar medulloblastoma.

Gutova M, Shackleford GM, Khankaldyyan V, Herrmann KA, Shi XH, Mittelholtz K, Abramyants Y, Blanchard MS, Kim SU, Annala AJ, Najbauer J, Synold TW, D'Apuzzo M, Barish ME, Moats RA, Aboody KS.

Gene Ther. 2013 Feb;20(2):143-50. doi: 10.1038/gt.2012.12. Epub 2012 Mar 8.

16.

Human neural stem cell tropism to metastatic breast cancer.

Zhao D, Najbauer J, Annala AJ, Garcia E, Metz MZ, Gutova M, Polewski MD, Gilchrist M, Glackin CA, Kim SU, Aboody KS.

Stem Cells. 2012 Feb;30(2):314-25. doi: 10.1002/stem.784.

17.

Therapeutic targeting of melanoma cells using neural stem cells expressing carboxylesterase, a CPT-11 activating enzyme.

Gutova M, Najbauer J, Chen MY, Potter PM, Kim SU, Aboody KS.

Curr Stem Cell Res Ther. 2010 Sep;5(3):273-6.

PMID:
19951251
18.

Iron labeling and pre-clinical MRI visualization of therapeutic human neural stem cells in a murine glioma model.

Thu MS, Najbauer J, Kendall SE, Harutyunyan I, Sangalang N, Gutova M, Metz MZ, Garcia E, Frank RT, Kim SU, Moats RA, Aboody KS.

PLoS One. 2009 Sep 29;4(9):e7218. doi: 10.1371/journal.pone.0007218.

19.

Neural stem cell tropism to glioma: critical role of tumor hypoxia.

Zhao D, Najbauer J, Garcia E, Metz MZ, Gutova M, Glackin CA, Kim SU, Aboody KS.

Mol Cancer Res. 2008 Dec;6(12):1819-29. doi: 10.1158/1541-7786.MCR-08-0146.

20.

Urokinase plasminogen activator and urokinase plasminogen activator receptor mediate human stem cell tropism to malignant solid tumors.

Gutova M, Najbauer J, Frank RT, Kendall SE, Gevorgyan A, Metz MZ, Guevorkian M, Edmiston M, Zhao D, Glackin CA, Kim SU, Aboody KS.

Stem Cells. 2008 Jun;26(6):1406-13. doi: 10.1634/stemcells.2008-0141. Epub 2008 Apr 10.

21.

Identification of uPAR-positive chemoresistant cells in small cell lung cancer.

Gutova M, Najbauer J, Gevorgyan A, Metz MZ, Weng Y, Shih CC, Aboody KS.

PLoS One. 2007 Feb 28;2(2):e243.

22.

Sub-attomole oligonucleotide and p53 cDNA determinations via a high-resolution surface plasmon resonance combined with oligonucleotide-capped gold nanoparticle signal amplification.

Yao X, Li X, Toledo F, Zurita-Lopez C, Gutova M, Momand J, Zhou F.

Anal Biochem. 2006 Jul 15;354(2):220-8. Epub 2006 May 6.

PMID:
16762306
23.

Formation of disulfide bond in p53 correlates with inhibition of DNA binding and tetramerization.

Sun XZ, Vinci C, Makmura L, Han S, Tran D, Nguyen J, Hamann M, Grazziani S, Sheppard S, Gutova M, Zhou F, Thomas J, Momand J.

Antioxid Redox Signal. 2003 Oct;5(5):655-65.

PMID:
14580323
24.

[Comparison of spectrophotometry methods of determining levels of theophylline in serum and their importance in clinical practice].

Reisová M, Gutová M, Vondra V.

Cas Lek Cesk. 1986 Sep 5;125(36):1137-9. Czech. No abstract available.

PMID:
3757007
25.

Present status and perspectives in the treatment of neurological disorders by dietary lecithin.

Gutová M, Masek K.

Acta Univ Carol Med (Praha). 1986;32(1-2):101-6. Review. No abstract available.

PMID:
3318328
26.

[Pharmacokinetics of theophylline in infants and toddlers with respiratory diseases].

Mrzena B, Gutová M, Janků I, Krebs V.

Cesk Pediatr. 1983 Aug;38(8):493-5. Czech. No abstract available.

PMID:
6627494
27.

A comparison between the efficacy of ketotifen and clemastine in children.

Hlousková Z, Gutová M, Hlousek Z.

J Int Med Res. 1980;8(6):408-12.

PMID:
6108265
28.

[Clinical pharmacology of acetylsalicylic acid].

Gutová M.

Cesk Pediatr. 1979 Jan;34(1):52-6. Review. Czech. No abstract available.

PMID:
367619
29.

[Clinical pharmacology of antiepileptics].

Gutová M.

Cesk Pediatr. 1978 Jan;33(1):26-36. Czech. No abstract available.

PMID:
657339
30.

[Problems in the preventive treatment of repeated febrile convulsions].

Vajnorský J, Gutová M, Ulrychová Z.

Cesk Pediatr. 1976 Nov;31(11):603-8. Czech. No abstract available.

PMID:
1017050
31.

[Beta-adrenergic receptor blocking agents in therapy].

Gutová M.

Cesk Pediatr. 1976 Nov;31(11):641-6. Czech. No abstract available.

PMID:
13936
32.

Kinetics of phenytoin in pregnant and non-pregnant rats.

Gutová M, Borgå O, Rane A.

Acta Pharmacol Toxicol (Copenh). 1976 Mar;38(3):254-9. No abstract available.

PMID:
988960
33.

[Prostaglandins and their effects in biology and medicine].

Gutová M.

Cesk Pediatr. 1976 Feb;31(2):77-81. Czech. No abstract available.

PMID:
1260934
34.

Effect of pregnancy on hepatic microsomal drug metabolism in rabbits and rats.

Gut I, Becker BA, Gutová M.

Arch Toxicol. 1976 Jan 30;35(1):41-7.

PMID:
946406
35.

Assay of the major (4-hydroxylated) metabolites of diphenylhydantoin in human urine.

Karlén B, Garle M, Rane A, Gutova M, Lindborg B.

Eur J Clin Pharmacol. 1975 Jun 13;8(5):359-63.

PMID:
1233236
36.

[Effect of tylosin in pigs].

Urbanová Z, Zahradníkova M, Schovánek V, Polák L, Rabas P, Sechser T, Svandová E, Raskova H, Raska K, Janovská D, Gutová M, Svĕrák V, Belinger A, Vanĕcek J, Zima L.

Vet Med (Praha). 1975 May;20(5):251-60. Czech.

PMID:
812238
37.

Identification of 5-(3,4-dihydroxyphenyl)-5-phenylhydantoin as a metabolite of 5,5-diphenylhydantoin (phenytoin) in rats and man.

Borgå O, Garle M, Gutová M.

Pharmacology. 1972;7(3):129-37. No abstract available.

PMID:
5054584
38.

Teratogenic effect of 6-azauridine in rats.

Gutová M, Elis J, Rasková H.

Teratology. 1971 Aug;4(3):287-94. No abstract available.

PMID:
5109584
39.

Transfer of 6-azauridine through the placental barrier in the rat.

Gutová M, Elis J, Rasková H.

Neoplasma. 1971;18(5):529-31. No abstract available.

PMID:
5165868
40.

[Bacteriocin-type inhibitors in fast growing saprophytic strains of mycobacteria].

Adámek L, Trnka L, Miŏn P, Gutová M.

Beitr Klin Erforsch Tuberk Lungenkr. 1968;138(1):51-5. German. No abstract available.

PMID:
5732149
41.

[New indication for 6-azauridine triacetate--psoriasis].

Rasková H, Elis J, Gutová M, Niznanská J, Mikulecký Z, Kubícková V, Borc K, Pribíková V, Hulínský K, Kantner V, Belsan I, Kuta A, Erbertová B, Kleibel K, Seycek V, Duchková H.

Cas Lek Cesk. 1967 Jul 28;106(31):870-3. Czech. No abstract available.

PMID:
4865916
42.

[Suitability of chemotherapy in early hypertension].

Rasková H, Gutová M, Elis J, Barcal M, Janda K, Huml V, Vomastek F, Vejvoda B.

Cas Lek Cesk. 1967 May 19;106(20):571-4. Czech. No abstract available.

PMID:
4865913

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