Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 62

1.

Predicting cancer outcomes from histology and genomics using convolutional networks.

Mobadersany P, Yousefi S, Amgad M, Gutman DA, Barnholtz-Sloan JS, Velázquez Vega JE, Brat DJ, Cooper LAD.

Proc Natl Acad Sci U S A. 2018 Mar 27;115(13):E2970-E2979. doi: 10.1073/pnas.1717139115. Epub 2018 Mar 12.

2.

Interactive phenotyping of large-scale histology imaging data with HistomicsML.

Nalisnik M, Amgad M, Lee S, Halani SH, Velazquez Vega JE, Brat DJ, Gutman DA, Cooper LAD.

Sci Rep. 2017 Nov 6;7(1):14588. doi: 10.1038/s41598-017-15092-3.

3.

The Digital Slide Archive: A Software Platform for Management, Integration, and Analysis of Histology for Cancer Research.

Gutman DA, Khalilia M, Lee S, Nalisnik M, Mullen Z, Beezley J, Chittajallu DR, Manthey D, Cooper LAD.

Cancer Res. 2017 Nov 1;77(21):e75-e78. doi: 10.1158/0008-5472.CAN-17-0629.

PMID:
29092945
4.

Results of the 2016 International Skin Imaging Collaboration International Symposium on Biomedical Imaging challenge: Comparison of the accuracy of computer algorithms to dermatologists for the diagnosis of melanoma from dermoscopic images.

Marchetti MA, Codella NCF, Dusza SW, Gutman DA, Helba B, Kalloo A, Mishra N, Carrera C, Celebi ME, DeFazio JL, Jaimes N, Marghoob AA, Quigley E, Scope A, Yélamos O, Halpern AC; International Skin Imaging Collaboration.

J Am Acad Dermatol. 2018 Feb;78(2):270-277.e1. doi: 10.1016/j.jaad.2017.08.016. Epub 2017 Sep 29.

PMID:
28969863
5.

Predicting clinical outcomes from large scale cancer genomic profiles with deep survival models.

Yousefi S, Amrollahi F, Amgad M, Dong C, Lewis JE, Song C, Gutman DA, Halani SH, Velazquez Vega JE, Brat DJ, Cooper LAD.

Sci Rep. 2017 Sep 15;7(1):11707. doi: 10.1038/s41598-017-11817-6.

6.

A Symmetry-Based Method to Infer Structural Brain Networks from Probabilistic Tractography Data.

Shadi K, Bakhshi S, Gutman DA, Mayberg HS, Dovrolis C.

Front Neuroinform. 2016 Nov 4;10:46. eCollection 2016.

7.

The molecular basis of breast cancer pathological phenotypes.

Heng YJ, Lester SC, Tse GM, Factor RE, Allison KH, Collins LC, Chen YY, Jensen KC, Johnson NB, Jeong JC, Punjabi R, Shin SJ, Singh K, Krings G, Eberhard DA, Tan PH, Korski K, Waldman FM, Gutman DA, Sanders M, Reis-Filho JS, Flanagan SR, Gendoo DM, Chen GM, Haibe-Kains B, Ciriello G, Hoadley KA, Perou CM, Beck AH.

J Pathol. 2017 Feb;241(3):375-391. doi: 10.1002/path.4847. Epub 2016 Dec 29.

8.

Imaging-genomics reveals driving pathways of MRI derived volumetric tumor phenotype features in Glioblastoma.

Grossmann P, Gutman DA, Dunn WD Jr, Holder CA, Aerts HJ.

BMC Cancer. 2016 Aug 8;16:611. doi: 10.1186/s12885-016-2659-5.

9.

REDLetr: Workflow and tools to support the migration of legacy clinical data capture systems to REDCap.

Dunn WD Jr, Cobb J, Levey AI, Gutman DA.

Int J Med Inform. 2016 Sep;93:103-10. doi: 10.1016/j.ijmedinf.2016.06.015. Epub 2016 Jun 27.

10.

Gene integrated set profile analysis: a context-based approach for inferring biological endpoints.

Kowalski J, Dwivedi B, Newman S, Switchenko JM, Pauly R, Gutman DA, Arora J, Gandhi K, Ainslie K, Doho G, Qin Z, Moreno CS, Rossi MR, Vertino PM, Lonial S, Bernal-Mizrachi L, Boise LH.

Nucleic Acids Res. 2016 Apr 20;44(7):e69. doi: 10.1093/nar/gkv1503. Epub 2016 Jan 29.

11.

Assessing the Effects of Software Platforms on Volumetric Segmentation of Glioblastoma.

Dunn WD Jr, Aerts HJWL, Cooper LA, Holder CA, Hwang SN, Jaffe CC, Brat DJ, Jain R, Flanders AE, Zinn PO, Colen RR, Gutman DA.

J Neuroimaging Psychiatry Neurol. 2016;1(2):64-72. doi: 10.17756/jnpn.2016-008. Epub 2016 Jul 20.

12.

Applicability of digital analysis and imaging technology in neuropathology assessment.

Dunn WD Jr, Gearing M, Park Y, Zhang L, Hanfelt J, Glass JD, Gutman DA.

Neuropathology. 2016 Jun;36(3):270-82. doi: 10.1111/neup.12273. Epub 2015 Nov 18.

13.

Fully automatic GBM segmentation in the TCGA-GBM dataset: Prognosis and correlation with VASARI features.

Rios Velazquez E, Meier R, Dunn WD Jr, Alexander B, Wiest R, Bauer S, Gutman DA, Reyes M, Aerts HJ.

Sci Rep. 2015 Nov 18;5:16822. doi: 10.1038/srep16822.

14.

A combinatorial radiographic phenotype may stratify patient survival and be associated with invasion and proliferation characteristics in glioblastoma.

Rao A, Rao G, Gutman DA, Flanders AE, Hwang SN, Rubin DL, Colen RR, Zinn PO, Jain R, Wintermark M, Kirby JS, Jaffe CC, Freymann J; TCGA Glioma Phenotype Research Group.

J Neurosurg. 2016 Apr;124(4):1008-17. doi: 10.3171/2015.4.JNS142732. Epub 2015 Oct 16.

15.

Somatic mutations associated with MRI-derived volumetric features in glioblastoma.

Gutman DA, Dunn WD Jr, Grossmann P, Cooper LA, Holder CA, Ligon KL, Alexander BM, Aerts HJ.

Neuroradiology. 2015 Dec;57(12):1227-37. doi: 10.1007/s00234-015-1576-7. Epub 2015 Sep 4.

16.

Organization of intrinsic functional brain connectivity predicts decisions to reciprocate social behavior.

Cáceda R, James GA, Gutman DA, Kilts CD.

Behav Brain Res. 2015 Oct 1;292:478-83. doi: 10.1016/j.bbr.2015.07.008. Epub 2015 Jul 9.

PMID:
26166191
17.

Voxel-based morphometry predicts shifts in dendritic spine density and morphology with auditory fear conditioning.

Keifer OP Jr, Hurt RC, Gutman DA, Keilholz SD, Gourley SL, Ressler KJ.

Nat Commun. 2015 Jul 7;6:7582. doi: 10.1038/ncomms8582.

18.

A Multidisciplinary Approach to Anesthetic Management of a Parturient with Severe Aortic Stenosis.

Tyagaraj K, Gutman DA, Belliveau L, Sadiq A, Bhutada A, Feierman DE.

Case Rep Anesthesiol. 2015;2015:489157. doi: 10.1155/2015/489157. Epub 2015 May 21.

19.

Novel genotype-phenotype associations in human cancers enabled by advanced molecular platforms and computational analysis of whole slide images.

Cooper LA, Kong J, Gutman DA, Dunn WD, Nalisnik M, Brat DJ.

Lab Invest. 2015 Apr;95(4):366-76. doi: 10.1038/labinvest.2014.153. Epub 2015 Jan 19. Review.

20.

An Interactive Learning Framework for Scalable Classification of Pathology Images.

Nalisnik M, Gutman DA, Kong J, Cooper LA.

Proc IEEE Int Conf Big Data. 2015 Oct-Nov;2015:928-935. Epub 2015 Dec 28.

21.

Virtual dissection and comparative connectivity of the superior longitudinal fasciculus in chimpanzees and humans.

Hecht EE, Gutman DA, Bradley BA, Preuss TM, Stout D.

Neuroimage. 2015 Mar;108:124-37. doi: 10.1016/j.neuroimage.2014.12.039. Epub 2014 Dec 20.

22.

Glioblastoma: imaging genomic mapping reveals sex-specific oncogenic associations of cell death.

Colen RR, Wang J, Singh SK, Gutman DA, Zinn PO.

Radiology. 2015 Apr;275(1):215-27. doi: 10.1148/radiol.14141800. Epub 2014 Dec 5.

PMID:
25490189
23.

A comparative analysis of mouse and human medial geniculate nucleus connectivity: a DTI and anterograde tracing study.

Keifer OP Jr, Gutman DA, Hecht EE, Keilholz SD, Ressler KJ.

Neuroimage. 2015 Jan 15;105:53-66. doi: 10.1016/j.neuroimage.2014.10.047. Epub 2014 Oct 23.

24.

Web based tools for visualizing imaging data and development of XNATView, a zero footprint image viewer.

Gutman DA, Dunn WD Jr, Cobb J, Stoner RM, Kalpathy-Cramer J, Erickson B.

Front Neuroinform. 2014 May 27;8:53. doi: 10.3389/fninf.2014.00053. eCollection 2014.

25.

Imaging genomic mapping of an invasive MRI phenotype predicts patient outcome and metabolic dysfunction: a TCGA glioma phenotype research group project.

Colen RR, Vangel M, Wang J, Gutman DA, Hwang SN, Wintermark M, Jain R, Jilwan-Nicolas M, Chen JY, Raghavan P, Holder CA, Rubin D, Huang E, Kirby J, Freymann J, Jaffe CC, Flanders A; TCGA Glioma Phenotype Research Group, Zinn PO.

BMC Med Genomics. 2014 Jun 2;7:30. doi: 10.1186/1755-8794-7-30.

26.

Acquisition of Paleolithic toolmaking abilities involves structural remodeling to inferior frontoparietal regions.

Hecht EE, Gutman DA, Khreisheh N, Taylor SV, Kilner J, Faisal AA, Bradley BA, Chaminade T, Stout D.

Brain Struct Funct. 2015 Jul;220(4):2315-31. doi: 10.1007/s00429-014-0789-6. Epub 2014 May 25.

PMID:
24859884
27.

Microembolism induces anhedonia but no detectable changes in white matter integrity in aged rats.

Nemeth CL, Gutman DA, Majeed W, Keilholz SD, Neigh GN.

PLoS One. 2014 May 8;9(5):e96624. doi: 10.1371/journal.pone.0096624. eCollection 2014.

28.

PACAP receptor gene polymorphism impacts fear responses in the amygdala and hippocampus.

Stevens JS, Almli LM, Fani N, Gutman DA, Bradley B, Norrholm SD, Reiser E, Ely TD, Dhanani R, Glover EM, Jovanovic T, Ressler KJ.

Proc Natl Acad Sci U S A. 2014 Feb 25;111(8):3158-63. doi: 10.1073/pnas.1318954111. Epub 2014 Feb 10.

29.

Differences in neural activation for object-directed grasping in chimpanzees and humans.

Hecht EE, Murphy LE, Gutman DA, Votaw JR, Schuster DM, Preuss TM, Orban GA, Stout D, Parr LA.

J Neurosci. 2013 Aug 28;33(35):14117-34. doi: 10.1523/JNEUROSCI.2172-13.2013.

30.

Social subordination stress and serotonin transporter polymorphisms: associations with brain white matter tract integrity and behavior in juvenile female macaques.

Howell BR, Godfrey J, Gutman DA, Michopoulos V, Zhang X, Nair G, Hu X, Wilson ME, Sanchez MM.

Cereb Cortex. 2014 Dec;24(12):3334-49. doi: 10.1093/cercor/bht187. Epub 2013 Aug 1.

31.

Cancer Digital Slide Archive: an informatics resource to support integrated in silico analysis of TCGA pathology data.

Gutman DA, Cobb J, Somanna D, Park Y, Wang F, Kurc T, Saltz JH, Brat DJ, Cooper LA.

J Am Med Inform Assoc. 2013 Nov-Dec;20(6):1091-8. doi: 10.1136/amiajnl-2012-001469. Epub 2013 Jul 25.

32.

Tumor-infiltrating lymphocytes in glioblastoma are associated with specific genomic alterations and related to transcriptional class.

Rutledge WC, Kong J, Gao J, Gutman DA, Cooper LA, Appin C, Park Y, Scarpace L, Mikkelsen T, Cohen ML, Aldape KD, McLendon RE, Lehman NL, Miller CR, Schniederjan MJ, Brennan CW, Saltz JH, Moreno CS, Brat DJ.

Clin Cancer Res. 2013 Sep 15;19(18):4951-60. doi: 10.1158/1078-0432.CCR-13-0551. Epub 2013 Jul 17.

33.

MR imaging predictors of molecular profile and survival: multi-institutional study of the TCGA glioblastoma data set.

Gutman DA, Cooper LA, Hwang SN, Holder CA, Gao J, Aurora TD, Dunn WD Jr, Scarpace L, Mikkelsen T, Jain R, Wintermark M, Jilwan M, Raghavan P, Huang E, Clifford RJ, Mongkolwat P, Kleper V, Freymann J, Kirby J, Zinn PO, Moreno CS, Jaffe C, Colen R, Rubin DL, Saltz J, Flanders A, Brat DJ.

Radiology. 2013 May;267(2):560-9. doi: 10.1148/radiol.13120118. Epub 2013 Feb 7.

34.

White matter integrity in highly traumatized adults with and without post-traumatic stress disorder.

Fani N, King TZ, Jovanovic T, Glover EM, Bradley B, Choi K, Ely T, Gutman DA, Ressler KJ.

Neuropsychopharmacology. 2012 Nov;37(12):2740-6. doi: 10.1038/npp.2012.146. Epub 2012 Aug 8.

35.

A DTI tractography analysis of infralimbic and prelimbic connectivity in the mouse using high-throughput MRI.

Gutman DA, Keifer OP Jr, Magnuson ME, Choi DC, Majeed W, Keilholz S, Ressler KJ.

Neuroimage. 2012 Nov 1;63(2):800-11. doi: 10.1016/j.neuroimage.2012.07.014. Epub 2012 Jul 14.

36.

Process versus product in social learning: comparative diffusion tensor imaging of neural systems for action execution-observation matching in macaques, chimpanzees, and humans.

Hecht EE, Gutman DA, Preuss TM, Sanchez MM, Parr LA, Rilling JK.

Cereb Cortex. 2013 May;23(5):1014-24. doi: 10.1093/cercor/bhs097. Epub 2012 Apr 25.

37.

Mapping of the mouse olfactory system with manganese-enhanced magnetic resonance imaging and diffusion tensor imaging.

Gutman DA, Magnuson M, Majeed W, Keifer OP Jr, Davis M, Ressler KJ, Keilholz S.

Brain Struct Funct. 2013 Mar;218(2):527-37. doi: 10.1007/s00429-012-0413-6. Epub 2012 Apr 24.

38.
39.

The tumor microenvironment strongly impacts master transcriptional regulators and gene expression class of glioblastoma.

Cooper LA, Gutman DA, Chisolm C, Appin C, Kong J, Rong Y, Kurc T, Van Meir EG, Saltz JH, Moreno CS, Brat DJ.

Am J Pathol. 2012 May;180(5):2108-19. doi: 10.1016/j.ajpath.2012.01.040. Epub 2012 Mar 20.

40.

Integrated morphologic analysis for the identification and characterization of disease subtypes.

Cooper LA, Kong J, Gutman DA, Wang F, Gao J, Appin C, Cholleti S, Pan T, Sharma A, Scarpace L, Mikkelsen T, Kurc T, Moreno CS, Brat DJ, Saltz JH.

J Am Med Inform Assoc. 2012 Mar-Apr;19(2):317-23. doi: 10.1136/amiajnl-2011-000700. Epub 2012 Jan 24.

41.

Subcallosal cingulate deep brain stimulation for treatment-resistant unipolar and bipolar depression.

Holtzheimer PE, Kelley ME, Gross RE, Filkowski MM, Garlow SJ, Barrocas A, Wint D, Craighead MC, Kozarsky J, Chismar R, Moreines JL, Mewes K, Posse PR, Gutman DA, Mayberg HS.

Arch Gen Psychiatry. 2012 Feb;69(2):150-8. doi: 10.1001/archgenpsychiatry.2011.1456. Epub 2012 Jan 2.

42.

Integrative, multimodal analysis of glioblastoma using TCGA molecular data, pathology images, and clinical outcomes.

Kong J, Cooper LA, Wang F, Gutman DA, Gao J, Chisolm C, Sharma A, Pan T, Van Meir EG, Kurc TM, Moreno CS, Saltz JH, Brat DJ.

IEEE Trans Biomed Eng. 2011 Dec;58(12):3469-74. doi: 10.1109/TBME.2011.2169256. Epub 2011 Sep 23.

43.

Persistent anxiolytic affects after chronic administration of the CRF₁ receptor antagonist R121919 in rats.

Gutman DA, Owens MJ, Thrivikraman KV, Nemeroff CB.

Neuropharmacology. 2011 Jun;60(7-8):1135-41. doi: 10.1016/j.neuropharm.2010.10.004. Epub 2010 Oct 14.

44.

The proneural molecular signature is enriched in oligodendrogliomas and predicts improved survival among diffuse gliomas.

Cooper LA, Gutman DA, Long Q, Johnson BA, Cholleti SR, Kurc T, Saltz JH, Brat DJ, Moreno CS.

PLoS One. 2010 Sep 3;5(9):e12548. doi: 10.1371/journal.pone.0012548.

45.

An integrative approach for in silico glioma research.

Cooper LA, Kong J, Gutman DA, Wang F, Cholleti SR, Pan TC, Widener PM, Sharma A, Mikkelsen T, Flanders AE, Rubin DL, Van Meir EG, Kurc TM, Moreno CS, Brat DJ, Saltz JH.

IEEE Trans Biomed Eng. 2010 Oct;57(10):2617-21. doi: 10.1109/TBME.2010.2060338. Epub 2010 Jul 23.

46.

A tractography analysis of two deep brain stimulation white matter targets for depression.

Gutman DA, Holtzheimer PE, Behrens TE, Johansen-Berg H, Mayberg HS.

Biol Psychiatry. 2009 Feb 15;65(4):276-82. doi: 10.1016/j.biopsych.2008.09.021. Epub 2008 Nov 14.

47.

Behavioral effects of the CRF1 receptor antagonist R121919 in rats selectively bred for high and low activity in the swim test.

Gutman DA, Coyer MJ, Boss-Williams KA, Owens MJ, Nemeroff CB, Weiss JM.

Psychoneuroendocrinology. 2008 Sep;33(8):1093-101. doi: 10.1016/j.psyneuen.2008.05.003. Epub 2008 Aug 3. Erratum in: Psychoneuroendocrinology. 2009 May;34(4):630-1.

PMID:
18676086
48.

Anatomical connectivity of the subgenual cingulate region targeted with deep brain stimulation for treatment-resistant depression.

Johansen-Berg H, Gutman DA, Behrens TE, Matthews PM, Rushworth MF, Katz E, Lozano AM, Mayberg HS.

Cereb Cortex. 2008 Jun;18(6):1374-83. Epub 2007 Oct 10.

PMID:
17928332
49.

The CRF1 receptor antagonist, R121919, attenuates the severity of precipitated morphine withdrawal.

Skelton KH, Oren D, Gutman DA, Easterling K, Holtzman SG, Nemeroff CB, Owens MJ.

Eur J Pharmacol. 2007 Sep 24;571(1):17-24. Epub 2007 Jun 5.

PMID:
17610870
50.

The CRF1 receptor antagonist R121919 attenuates the neuroendocrine and behavioral effects of precipitated lorazepam withdrawal.

Skelton KH, Gutman DA, Thrivikraman KV, Nemeroff CB, Owens MJ.

Psychopharmacology (Berl). 2007 Jun;192(3):385-96. Epub 2007 Feb 13.

PMID:
17297634

Supplemental Content

Loading ...
Support Center