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Items: 9

1.

Desensitization of human CRF2(a) receptor signaling governed by agonist potency and βarrestin2 recruitment.

Hauger RL, Olivares-Reyes JA, Braun S, Hernandez-Aranda J, Hudson CC, Gutknecht E, Dautzenberg FM, Oakley RH.

Regul Pept. 2013 Sep 10;186:62-76. doi: 10.1016/j.regpep.2013.06.009. Epub 2013 Jun 29.

2.

Corticotropin-releasing factor receptors induce calcium mobilization through cross-talk with Gq-coupled receptors.

Gutknecht E, Vauquelin G, Dautzenberg FM.

Eur J Pharmacol. 2010 Sep 10;642(1-3):1-9. doi: 10.1016/j.ejphar.2010.05.027. Epub 2010 Jun 8.

PMID:
20594969
3.

Corticotropin releasing factor-induced ERK phosphorylation in AtT20 cells occurs via a cAMP-dependent mechanism requiring EPAC2.

Van Kolen K, Dautzenberg FM, Verstraeten K, Royaux I, De Hoogt R, Gutknecht E, Peeters PJ.

Neuropharmacology. 2010 Jan;58(1):135-44. doi: 10.1016/j.neuropharm.2009.06.022. Epub 2009 Jun 30. Erratum in: Neuropharmacology. 2010 Feb;58(2):559. Dautzenberg, Frank M [added].

PMID:
19573542
4.

Molecular mechanisms of corticotropin-releasing factor receptor-induced calcium signaling.

Gutknecht E, Van der Linden I, Van Kolen K, Verhoeven KF, Vauquelin G, Dautzenberg FM.

Mol Pharmacol. 2009 Mar;75(3):648-57. doi: 10.1124/mol.108.050427. Epub 2008 Dec 19.

PMID:
19098121
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7.

Effects of methoxychlor, dieldrin and lindane on sea urchin fertilization and early development.

Pesando D, Robert S, Huitorel P, Gutknecht E, Pereira L, Girard JP, Ciapa B.

Aquat Toxicol. 2004 Feb 25;66(3):225-39.

PMID:
15129766
8.

Development of a virtual screening method for identification of "frequent hitters" in compound libraries.

Roche O, Schneider P, Zuegge J, Guba W, Kansy M, Alanine A, Bleicher K, Danel F, Gutknecht EM, Rogers-Evans M, Neidhart W, Stalder H, Dillon M, Sjögren E, Fotouhi N, Gillespie P, Goodnow R, Harris W, Jones P, Taniguchi M, Tsujii S, von der Saal W, Zimmermann G, Schneider G.

J Med Chem. 2002 Jan 3;45(1):137-42.

PMID:
11754585
9.

Structure-based design of beta-lactamase inhibitors. 1. Synthesis and evaluation of bridged monobactams.

Heinze-Krauss I, Angehrn P, Charnas RL, Gubernator K, Gutknecht EM, Hubschwerlen C, Kania M, Oefner C, Page MG, Sogabe S, Specklin JL, Winkler F.

J Med Chem. 1998 Oct 8;41(21):3961-71.

PMID:
9767633

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