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Items: 1 to 50 of 133

1.

US immigration order strikes against biotech.

Levin JM, Holtzman SH, Maraganore J, Hastings PJ, Cohen R, Dahiyat B, Adams J, Adams C, Ahrens B, Albers J, Aspinall MG, Audia JE, Babler M, Barrett P, Barry Z, Bermingham N, Bloch S, Blum RI, Bolno PB, Bonney MW, Booth B, Bradbury DM, Brauer SK, Byers B, Cagnoni PJ, Cali BM, Ciechanover I, Clark C, Clayman MD, Cleland JL, Cobb P, Cooper R, Currie MG, Diekman J, Dobmeier EL, Doerfler D, Donley EL, Dunsire D, During M, Eckstein JW, Elenko E, Exter NA, Fleming JJ, Flesher GJ, Formela JF, Forrester R, Francois C, Franklin H, Freeman MW, Furst H, Gage LP, Galakatos N, Gallagher BM, Geraghty JA, Gill S, Goeddel DV, Goldsmith MA, Gowen M, Goyal V, Graney T, Grayzel D, Greene B, Grint P, Gutierrez-Ramos JC, Haney B, Ha-Ngoc T, Harris T, Hasnain F, Hata YS, Hecht P, Henshaw L, Heyman R, Hoppenot H, Horvitz HR, Hughes TE, Hutton WS, Isaacs ST, Jenkins A, Jonker J, Kaplan J, Karsen P, Keiper J, Kim J, Kindler J, King R, King V, Kjellson N, Koenig S, Koenig G, Kolchinsky P, Laikind P, Langer RB, Lee JJ, Leff JS, Leicher BA, Leschly N, Levin A, Levin M, Levine AJ, Levy A, Liu DR, Lodish HF, Lopatin U, Love TW, Macdonald G, Maderis GJ, Mahadevia A, Mahanthappa NK, Martin JF, Martin A, Martucci WE, McArthur JG, McCann CM, McCarthy SA, McDonough CG, Mendlein J, Miller L, Miralles D, Moch KI, More B, Myers AG, Narachi MA, Nashat A, Nelson W, Newell WJ, Olle B, Osborn JE, Owens JC, Pande A, Papadopoulos S, Parker HS, Parmar KM, Patterson MR, Paul SM, Perez R, Perry M, Pfeffer CG, Powell M, Pruzanski M, Purcell DJ, Rakhit A, Ramamoorthi K, Rastetter W, Rawcliffe AA, Reid LE, Renaud RC, Rhodes JP, Rieflin WJ, Robins C, Rocklage SM, Rosenblatt M, Rosin JG, Rutter WJ, Saha S, Samuels C, Sato VL, Scangos G, Scarlett JA, Schenkein D, Schreiber SL, Schwab A, Sekhri P, Shah R, Shenk T, Siegall CB, Simon NJ, Simonian N, Stein J, Su M, Szela MT, Taglietti M, Tandon N, Termeer H, Thornberry NA, Tolar M, Ulevitch R, Vaishnaw AK, VanLent A, Varsavsky M, Vlasuk GP, Vounatsos M, Waksal SG, Warma N, Watts RJ, Werber Y, Westphal C, Wierenga W, Williams DE, Williams LR, Xanthopoulos KG, Zohar D, Zweifach SS.

Nat Biotechnol. 2017 Mar 7;35(3):204-206. doi: 10.1038/nbt.3824. No abstract available.

PMID:
28267733
2.

Coordinated involvement of mast cells and T cells in allergic mucosal inflammation: critical role of the CC chemokine ligand 1:CCR8 axis.

Gonzalo JA, Qiu Y, Lora JM, Al-Garawi A, Villeval JL, Boyce JA, Martinez-A C, Marquez G, Goya I, Hamid Q, Fraser CC, Picarella D, Cote-Sierra J, Hodge MR, Gutierrez-Ramos JC, Kolbeck R, Coyle AJ.

J Immunol. 2007 Aug 1;179(3):1740-50.

3.

Tumor necrosis factor-alpha triggers mucus production in airway epithelium through an IkappaB kinase beta-dependent mechanism.

Lora JM, Zhang DM, Liao SM, Burwell T, King AM, Barker PA, Singh L, Keaveney M, Morgenstern J, Gutiérrez-Ramos JC, Coyle AJ, Fraser CC.

J Biol Chem. 2005 Oct 28;280(43):36510-7. Epub 2005 Aug 25.

4.

Major reduction of atherosclerosis in fractalkine (CX3CL1)-deficient mice is at the brachiocephalic artery, not the aortic root.

Teupser D, Pavlides S, Tan M, Gutierrez-Ramos JC, Kolbeck R, Breslow JL.

Proc Natl Acad Sci U S A. 2004 Dec 21;101(51):17795-800. Epub 2004 Dec 13.

5.

Intranasal exposure of mice to house dust mite elicits allergic airway inflammation via a GM-CSF-mediated mechanism.

Cates EC, Fattouh R, Wattie J, Inman MD, Goncharova S, Coyle AJ, Gutierrez-Ramos JC, Jordana M.

J Immunol. 2004 Nov 15;173(10):6384-92.

6.

Effect of inducible costimulator blockade on the pathological and protective immune responses induced by the gastrointestinal helminth Trichinella spiralis.

Scales HE, Ierna MX, Gutierrez-Ramos JC, Coyle AJ, Garside P, Lawrence CE.

Eur J Immunol. 2004 Oct;34(10):2854-62.

7.

ICOS-mediated signaling regulates cytokine production by human T cells and provides a unique signal to selectively control the clonal expansion of Th2 helper cells.

Vieira PL, Wassink L, Smith LM, Nam S, Kingsbury GA, Gutierrez-Ramos JC, Coyle AJ, Kapsenberg ML, Wierenga EA.

Eur J Immunol. 2004 May;34(5):1282-90.

8.

The role of ICOS and other costimulatory molecules in allergy and asthma.

Coyle AJ, Gutierrez-Ramos JC.

Springer Semin Immunopathol. 2004 Feb;25(3-4):349-59. Epub 2004 Jan 14. Review.

PMID:
14999428
9.

Blocking inducible co-stimulator in the absence of CD28 impairs Th1 and CD25+ regulatory T cells in murine colitis.

de Jong YP, Rietdijk ST, Faubion WA, Abadia-Molina AC, Clarke K, Mizoguchi E, Tian J, Delaney T, Manning S, Gutierrez-Ramos JC, Bhan AK, Coyle AJ, Terhorst C.

Int Immunol. 2004 Feb;16(2):205-13.

PMID:
14734605
10.

Informatics and the immune system: the expanding IL-1 and B7 protein families.

Grant EP, Coyle AJ, Gutierrez-Ramos JC.

Semin Immunol. 2003 Aug;15(4):225-31.

PMID:
14690047
11.

The proteasome of Mycobacterium tuberculosis is required for resistance to nitric oxide.

Darwin KH, Ehrt S, Gutierrez-Ramos JC, Weich N, Nathan CF.

Science. 2003 Dec 12;302(5652):1963-6.

12.

FcepsilonRI-dependent gene expression in human mast cells is differentially controlled by T helper type 2 cytokines.

Lora JM, Al-Garawi A, Pickard MD, Price KS, Bagga S, Sicoli J, Hodge MR, Gutiérrez-Ramos JC, Briskin MJ, Boyce JA.

J Allergy Clin Immunol. 2003 Dec;112(6):1119-26.

PMID:
14657870
13.

Continuous exposure to house dust mite elicits chronic airway inflammation and structural remodeling.

Johnson JR, Wiley RE, Fattouh R, Swirski FK, Gajewska BU, Coyle AJ, Gutierrez-Ramos JC, Ellis R, Inman MD, Jordana M.

Am J Respir Crit Care Med. 2004 Feb 1;169(3):378-85. Epub 2003 Nov 3.

PMID:
14597485
14.

Animal models to study chemokine receptor function: in vivo mouse models of allergic airway inflammation.

Lloyd CM, Gutierrez-Ramos JC.

Methods Mol Biol. 2004;239:199-210. No abstract available.

PMID:
14573920
15.

Chemokines acting via CXCR2 and CXCR4 control the release of neutrophils from the bone marrow and their return following senescence.

Martin C, Burdon PC, Bridger G, Gutierrez-Ramos JC, Williams TJ, Rankin SM.

Immunity. 2003 Oct;19(4):583-93.

16.

Tim-3 inhibits T helper type 1-mediated auto- and alloimmune responses and promotes immunological tolerance.

Sánchez-Fueyo A, Tian J, Picarella D, Domenig C, Zheng XX, Sabatos CA, Manlongat N, Bender O, Kamradt T, Kuchroo VK, Gutiérrez-Ramos JC, Coyle AJ, Strom TB.

Nat Immunol. 2003 Nov;4(11):1093-101. Epub 2003 Oct 12.

PMID:
14556005
17.

Overlapping and selective roles of endothelial intercellular adhesion molecule-1 (ICAM-1) and ICAM-2 in lymphocyte trafficking.

Lehmann JC, Jablonski-Westrich D, Haubold U, Gutierrez-Ramos JC, Springer T, Hamann A.

J Immunol. 2003 Sep 1;171(5):2588-93.

18.

Role of regulator of G protein signaling 16 in inflammation-induced T lymphocyte migration and activation.

Lippert E, Yowe DL, Gonzalo JA, Justice JP, Webster JM, Fedyk ER, Hodge M, Miller C, Gutierrez-Ramos JC, Borrego F, Keane-Myers A, Druey KM.

J Immunol. 2003 Aug 1;171(3):1542-55.

19.

Activated human hepatic stellate cells express the renin-angiotensin system and synthesize angiotensin II.

Bataller R, Sancho-Bru P, Ginès P, Lora JM, Al-Garawi A, Solé M, Colmenero J, Nicolás JM, Jiménez W, Weich N, Gutiérrez-Ramos JC, Arroyo V, Rodés J.

Gastroenterology. 2003 Jul;125(1):117-25.

PMID:
12851877
20.

More negative feedback?

Coyle AJ, Gutierrez-Ramos JC.

Nat Immunol. 2003 Jul;4(7):647-8. No abstract available.

PMID:
12830142
21.

CC chemokine receptor 9 expression defines a subset of peripheral blood lymphocytes with mucosal T cell phenotype and Th1 or T-regulatory 1 cytokine profile.

Papadakis KA, Landers C, Prehn J, Kouroumalis EA, Moreno ST, Gutierrez-Ramos JC, Hodge MR, Targan SR.

J Immunol. 2003 Jul 1;171(1):159-65.

22.

Effect of GM-CSF on immune, inflammatory, and clinical responses to ragweed in a novel mouse model of mucosal sensitization.

Cates EC, Gajewska BU, Goncharova S, Alvarez D, Fattouh R, Coyle AJ, Gutierrez-Ramos JC, Jordana M.

J Allergy Clin Immunol. 2003 May;111(5):1076-86.

PMID:
12743573
23.

Absence of CCR8 does not impair the response to ovalbumin-induced allergic airway disease.

Goya I, Villares R, Zaballos A, Gutiérrez J, Kremer L, Gonzalo JA, Varona R, Carramolino L, Serrano A, Pallarés P, Criado LM, Kolbeck R, Torres M, Coyle AJ, Gutiérrez-Ramos JC, Martínez-A C, Márquez G.

J Immunol. 2003 Feb 15;170(4):2138-46.

24.

Essential role for the C5a receptor in regulating the effector phase of synovial infiltration and joint destruction in experimental arthritis.

Grant EP, Picarella D, Burwell T, Delaney T, Croci A, Avitahl N, Humbles AA, Gutierrez-Ramos JC, Briskin M, Gerard C, Coyle AJ.

J Exp Med. 2002 Dec 2;196(11):1461-71.

25.

Programmed death-1 targeting can promote allograft survival.

Ozkaynak E, Wang L, Goodearl A, McDonald K, Qin S, O'Keefe T, Duong T, Smith T, Gutierrez-Ramos JC, Rottman JB, Coyle AJ, Hancock WW.

J Immunol. 2002 Dec 1;169(11):6546-53.

26.

Characterization of signaling pathways activated by the interleukin 1 (IL-1) receptor homologue T1/ST2. A role for Jun N-terminal kinase in IL-4 induction.

Brint EK, Fitzgerald KA, Smith P, Coyle AJ, Gutierrez-Ramos JC, Fallon PG, O'Neill LA.

J Biol Chem. 2002 Dec 20;277(51):49205-11. Epub 2002 Oct 3.

27.

Granulocyte macrophage colony-stimulating factor-driven respiratory mucosal sensitization induces Th2 differentiation and function independently of interleukin-4.

Ritz SA, Cundall MJ, Gajewska BU, Alvarez D, Gutierrez-Ramos JC, Coyle AJ, McKenzie AN, Stämpfli MR, Jordana M.

Am J Respir Cell Mol Biol. 2002 Oct;27(4):428-35.

PMID:
12356576
28.

Expression of the chemokines MCP-1/CCL2 and RANTES/CCL5 is differentially regulated by infiltrating inflammatory cells.

Haberstroh U, Pocock J, Gómez-Guerrero C, Helmchen U, Hamann A, Gutierrez-Ramos JC, Stahl RA, Thaiss F.

Kidney Int. 2002 Oct;62(4):1264-76.

29.

Ectopic expression of Delta4 impairs hematopoietic development and leads to lymphoproliferative disease.

Dorsch M, Zheng G, Yowe D, Rao P, Wang Y, Shen Q, Murphy C, Xiong X, Shi Q, Gutierrez-Ramos JC, Fraser C, Villeval JL.

Blood. 2002 Sep 15;100(6):2046-55.

30.

Gene expression profiles: creating new perspectives in arthritis research.

Grant EP, Pickard MD, Briskin MJ, Gutierrez-Ramos JC.

Arthritis Rheum. 2002 Apr;46(4):874-84. Review. No abstract available.

31.

Inhalation of a harmless antigen (ovalbumin) elicits immune activation but divergent immunoglobulin and cytokine activities in mice.

Swirski FK, Gajewska BU, Alvarez D, Ritz SA, Cundall MJ, Cates EC, Coyle AJ, Gutierrez-Ramos JC, Inman MD, Jordana M, Stämpfli MR.

Clin Exp Allergy. 2002 Mar;32(3):411-21.

PMID:
11940072
32.

Modulation of LIGHT-HVEM costimulation prolongs cardiac allograft survival.

Ye Q, Fraser CC, Gao W, Wang L, Busfield SJ, Wang C, Qiu Y, Coyle AJ, Gutierrez-Ramos JC, Hancock WW.

J Exp Med. 2002 Mar 18;195(6):795-800.

33.

Identification and characterization of SF2000 and SF2001, two new members of the immune receptor SLAM/CD2 family.

Fraser CC, Howie D, Morra M, Qiu Y, Murphy C, Shen Q, Gutierrez-Ramos JC, Coyle A, Kingsbury GA, Terhorst C.

Immunogenetics. 2002 Feb;53(10-11):843-50. Epub 2002 Jan 23.

PMID:
11862385
34.

Temporal-spatial analysis of the immune response in a murine model of ovalbumin-induced airways inflammation.

Gajewska BU, Swirski FK, Alvarez D, Ritz SA, Goncharova S, Cundall M, Snider DP, Coyle AJ, Gutierrez-Ramos JC, Stämpfli MR, Jordana M.

Am J Respir Cell Mol Biol. 2001 Sep;25(3):326-34.

PMID:
11588010
35.

Microarrays for studying the host transcriptional response to microbial infection and for the identification of host drug targets.

Yowe D, Cook WJ, Gutierrez-Ramos JC.

Microbes Infect. 2001 Aug;3(10):813-21. Review.

PMID:
11580976
36.

Generation of experimental allergic airways inflammation in the absence of draining lymph nodes.

Gajewska BU, Alvarez D, Vidric M, Goncharova S, Stämpfli MR, Coyle AJ, Gutierrez-Ramos JC, Jordana M.

J Clin Invest. 2001 Aug;108(4):577-83.

37.

Leukocyte recruitment and neuroglial activation during facial nerve regeneration in ICAM-1-deficient mice: effects of breeding strategy.

Werner A, Martin S, Gutierrez-Ramos JC, Raivich G.

Cell Tissue Res. 2001 Jul;305(1):25-41.

PMID:
11512669
38.

Phosphatidylinositol 3-kinase-dependent extracellular calcium influx is essential for CX(3)CR1-mediated activation of the mitogen-activated protein kinase cascade.

Kansra V, Groves C, Gutierrez-Ramos JC, Polakiewicz RD.

J Biol Chem. 2001 Aug 24;276(34):31831-8. Epub 2001 Jun 29.

39.

The costimulatory molecule ICOS plays an important role in the immunopathogenesis of EAE.

Rottman JB, Smith T, Tonra JR, Ganley K, Bloom T, Silva R, Pierce B, Gutierrez-Ramos JC, Ozkaynak E, Coyle AJ.

Nat Immunol. 2001 Jul;2(7):605-11.

PMID:
11429544
40.

ICOS is critical for T helper cell-mediated lung mucosal inflammatory responses.

Gonzalo JA, Tian J, Delaney T, Corcoran J, Rottman JB, Lora J, Al-garawi A, Kroczek R, Gutierrez-Ramos JC, Coyle AJ.

Nat Immunol. 2001 Jul;2(7):597-604.

PMID:
11429543
41.

Importance of ICOS-B7RP-1 costimulation in acute and chronic allograft rejection.

Ozkaynak E, Gao W, Shemmeri N, Wang C, Gutierrez-Ramos JC, Amaral J, Qin S, Rottman JB, Coyle AJ, Hancock WW.

Nat Immunol. 2001 Jul;2(7):591-6.

PMID:
11429542
42.

A major role for VCAM-1, but not ICAM-1, in early atherosclerosis.

Cybulsky MI, Iiyama K, Li H, Zhu S, Chen M, Iiyama M, Davis V, Gutierrez-Ramos JC, Connelly PW, Milstone DS.

J Clin Invest. 2001 May;107(10):1255-62.

43.

Mouse models of allergic airway disease.

Lloyd CM, Gonzalo JA, Coyle AJ, Gutierrez-Ramos JC.

Adv Immunol. 2001;77:263-95. Review. No abstract available.

PMID:
11293118
44.

Inhibition of T1/ST2 during respiratory syncytial virus infection prevents T helper cell type 2 (Th2)- but not Th1-driven immunopathology.

Walzl G, Matthews S, Kendall S, Gutierrez-Ramos JC, Coyle AJ, Openshaw PJ, Hussell T.

J Exp Med. 2001 Apr 2;193(7):785-92.

45.

Chemokine stromal cell-derived factor-1alpha modulates VLA-4 integrin-dependent adhesion to fibronectin and VCAM-1 on bone marrow hematopoietic progenitor cells.

Hidalgo A, Sanz-Rodríguez F, Rodríguez-Fernández JL, Albella B, Blaya C, Wright N, Cabañas C, Prósper F, Gutierrez-Ramos JC, Teixidó J.

Exp Hematol. 2001 Mar;29(3):345-55.

PMID:
11274763
46.

The expanding B7 superfamily: increasing complexity in costimulatory signals regulating T cell function.

Coyle AJ, Gutierrez-Ramos JC.

Nat Immunol. 2001 Mar;2(3):203-9. Review.

PMID:
11224518
47.

Regulation and function of T1/ST2 expression on CD4+ T cells: induction of type 2 cytokine production by T1/ST2 cross-linking.

Meisel C, Bonhagen K, Löhning M, Coyle AJ, Gutierrez-Ramos JC, Radbruch A, Kamradt T.

J Immunol. 2001 Mar 1;166(5):3143-50.

48.

Expression of the Th1 chemokine IFN-gamma-inducible protein 10 in the airway alters mucosal allergic sensitization in mice.

Wiley R, Palmer K, Gajewska B, Stämpfli M, Alvarez D, Coyle A, Gutierrez-Ramos J, Jordana M.

J Immunol. 2001 Feb 15;166(4):2750-9.

49.

Resolution of bronchial hyperresponsiveness and pulmonary inflammation is associated with IL-3 and tissue leukocyte apoptosis.

Lloyd CM, Gonzalo JA, Nguyen T, Delaney T, Tian J, Oettgen H, Coyle AJ, Gutierrez-Ramos JC.

J Immunol. 2001 Feb 1;166(3):2033-40.

50.

Non-redundant functional groups of chemokines operate in a coordinate manner during the inflammatory response in the lung.

Gutierrez-Ramos JC, Lloyd C, Kapsenberg ML, Gonzalo JA, Coyle AJ.

Immunol Rev. 2000 Oct;177:31-42. Review.

PMID:
11138782

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