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Items: 30

1.

Discovery of New AKT1 Inhibitors by Combination of In silico Structure Based Virtual Screening Approaches and Biological Evaluations.

Fratev F, Gutierrez DA, Aguilera RJ, Tyagi A, Damodaran C, Sirimulla S.

J Biomol Struct Dyn. 2020 Jan 14:1-11. doi: 10.1080/07391102.2020.1715835. [Epub ahead of print]

PMID:
31933423
2.

c-Abl Deficiency Provides Synaptic Resiliency Against Aβ-Oligomers.

Gutierrez DA, Vargas LM, Chandia-Cristi A, de la Fuente C, Leal N, Alvarez AR.

Front Cell Neurosci. 2019 Nov 26;13:526. doi: 10.3389/fncel.2019.00526. eCollection 2019.

3.

Impaired insulin signaling in the B10.D2-Hc0 H2d H2-T18c/oSnJ mouse model of complement factor 5 deficiency.

Peterson KR, Gutierrez DA, Kikuchi T, Anderson-Baucum EK, Winn NC, Shuey MM, Bolus WR, McGuinness OP, Hasty AH.

Am J Physiol Endocrinol Metab. 2019 Aug 1;317(2):E200-E211. doi: 10.1152/ajpendo.00042.2019. Epub 2019 May 14.

PMID:
31084499
4.

Recombinant human lactoferrin induces apoptosis, disruption of F-actin structure and cell cycle arrest with selective cytotoxicity on human triple negative breast cancer cells.

Iglesias-Figueroa BF, Siqueiros-Cendón TS, Gutierrez DA, Aguilera RJ, Espinoza-Sánchez EA, Arévalo-Gallegos S, Varela-Ramirez A, Rascón-Cruz Q.

Apoptosis. 2019 Aug;24(7-8):562-577. doi: 10.1007/s10495-019-01539-7.

PMID:
30941553
5.

A new pyridazinone exhibits potent cytotoxicity on human cancer cells via apoptosis and poly-ubiquitinated protein accumulation.

Gutierrez DA, DeJesus RE, Contreras L, Rodriguez-Palomares IA, Villanueva PJ, Balderrama KS, Monterroza L, Larragoity M, Varela-Ramirez A, Aguilera RJ.

Cell Biol Toxicol. 2019 Dec;35(6):503-519. doi: 10.1007/s10565-019-09466-8. Epub 2019 Mar 1.

6.

Predicting Human miRNA-like Sequences within Human Papillomavirus Genomes.

Gutiérrez DA, Varela-Ramírez A, Rodríguez-Esquivel M, Mendoza-Rodríguez MG, Ayala-Sumuano JT, Pineda D, Garrido-Guerrero E, Jiménez-Vega F, Aguilar S, Quiñones M, Nambo MJ, Chávez-Olmos P, Taniguchi-Ponciano K, Marrero-Rodriguez D, Romero-Morelos P, Castro JP, Bandala C, Carrillo-Romero A, González-Yebra B, Salcedo M.

Arch Med Res. 2018 Jul;49(5):323-334. doi: 10.1016/j.arcmed.2018.10.008. Epub 2018 Nov 3.

PMID:
30401587
7.

Pyronaridine exerts potent cytotoxicity on human breast and hematological cancer cells through induction of apoptosis.

Villanueva PJ, Martinez A, Baca ST, DeJesus RE, Larragoity M, Contreras L, Gutierrez DA, Varela-Ramirez A, Aguilera RJ.

PLoS One. 2018 Nov 5;13(11):e0206467. doi: 10.1371/journal.pone.0206467. eCollection 2018.

8.

A new family of fullerene derivatives: Fullerene-curcumin conjugates for biological and photovoltaic applications.

Castro E, Cerón MR, Garcia AH, Kim Q, Etcheverry-Berríos A, Morel M, Díaz-Torres R, Qian W, Martinez Z, Mendez L, Perez F, Santoyo CA, Gimeno-Muñoz R, Esper R, Gutierrez DA, Varela-Ramirez A, Aguilera RJ, Llano M, Soler M, Aliaga-Alcalde N, Echegoyen L.

RSC Adv. 2018;8(73):41692-41698. doi: 10.1039/C8RA08334G. Epub 2018 Dec 13.

9.

Palladium-Catalyzed Direct C(sp2)-H ortho-Arylation of Anilides Using 2-Aminophenylpyrazole as the Directing Group.

Shen Y, Cindy Lee WC, Gutierrez DA, Li JJ.

J Org Chem. 2017 Nov 3;82(21):11620-11625. doi: 10.1021/acs.joc.7b01883.

PMID:
29016134
10.

Functional analysis of four single (RGDWL, RGDWM, RGDWP, RGDMN) and two double (RGDNM, RGDMP) mutants: The importance of methionine (M) in the functional potency of recombinant mojastin (r-Moj).

Gutierrez DA, Aranda AS, Carrillo DA, Koshlaychuk MA, Sanchez EE, Lucena SE, Soto JG.

Toxicon. 2016 Dec 15;124:1-7. doi: 10.1016/j.toxicon.2016.11.002. Epub 2016 Nov 2.

11.

Of Mouse Models of Mast Cell Deficiency and Metabolic Syndrome.

Feyerabend TB, Gutierrez DA, Rodewald HR.

Cell Metab. 2016 Jul 12;24(1):1-2. doi: 10.1016/j.cmet.2016.06.019. No abstract available.

12.

2-Aminophenyl-1H-pyrazole as a Removable Directing Group for Copper-Mediated C-H Amidation and Sulfonamidation.

Lee WC, Shen Y, Gutierrez DA, Li JJ.

Org Lett. 2016 Jun 3;18(11):2660-3. doi: 10.1021/acs.orglett.6b01105. Epub 2016 May 12.

PMID:
27172121
13.

Functional characterization of six aspartate (D) recombinant mojastin mutants (r-Moj): A second aspartate amino acid carboxyl to the RGD in r-Moj-D_ peptides is not sufficient to induce apoptosis of SK-Mel-28 cells.

Ramos CJ, Gutierrez DA, Aranda AS, Koshlaychuk MA, Carrillo DA, Medrano R, McBride TD, U A, Medina SM, Lombardo MC, Lucena SE, Sanchez EE, Soto JG.

Toxicon. 2016 Aug;118:36-42. doi: 10.1016/j.toxicon.2016.04.038. Epub 2016 Apr 20.

14.

Poly(ADP-ribose) polymerase-1 silences retroviruses independently of viral DNA integration or heterochromatin formation.

Gutierrez DA, Valdes L, Serguera C, Llano M.

J Gen Virol. 2016 Jul;97(7):1686-1692. doi: 10.1099/jgv.0.000466. Epub 2016 Mar 30.

PMID:
27028089
15.

Hematopoietic Kit Deficiency, rather than Lack of Mast Cells, Protects Mice from Obesity and Insulin Resistance.

Gutierrez DA, Muralidhar S, Feyerabend TB, Herzig S, Rodewald HR.

Cell Metab. 2015 May 5;21(5):678-91. doi: 10.1016/j.cmet.2015.04.013.

16.

CCR2 deficiency leads to increased eosinophils, alternative macrophage activation, and type 2 cytokine expression in adipose tissue.

Bolus WR, Gutierrez DA, Kennedy AJ, Anderson-Baucum EK, Hasty AH.

J Leukoc Biol. 2015 Oct;98(4):467-77. doi: 10.1189/jlb.3HI0115-018R. Epub 2015 May 1.

17.

Type 1 diabetes in NOD mice unaffected by mast cell deficiency.

Gutierrez DA, Fu W, Schonefeldt S, Feyerabend TB, Ortiz-Lopez A, Lampi Y, Liston A, Mathis D, Rodewald HR.

Diabetes. 2014 Nov;63(11):3827-34. doi: 10.2337/db14-0372. Epub 2014 Jun 10.

18.

What have we really learned about macrophage recruitment to adipose tissue?

Hasty AH, Gutierrez DA.

Endocrinology. 2014 Jan;155(1):12-4. doi: 10.1210/en.2013-2027. No abstract available.

19.

A sting in the tale of TH2 immunity.

Gutierrez DA, Rodewald HR.

Immunity. 2013 Nov 14;39(5):803-5. doi: 10.1016/j.immuni.2013.10.015.

20.

NO-dependent CaMKII activation during β-adrenergic stimulation of cardiac muscle.

Gutierrez DA, Fernandez-Tenorio M, Ogrodnik J, Niggli E.

Cardiovasc Res. 2013 Dec 1;100(3):392-401. doi: 10.1093/cvr/cvt201. Epub 2013 Aug 20.

21.

Weight cycling increases T-cell accumulation in adipose tissue and impairs systemic glucose tolerance.

Anderson EK, Gutierrez DA, Kennedy A, Hasty AH.

Diabetes. 2013 Sep;62(9):3180-8. doi: 10.2337/db12-1076. Epub 2013 Jun 3.

22.

Impact of macrophage inflammatory protein-1α deficiency on atherosclerotic lesion formation, hepatic steatosis, and adipose tissue expansion.

Kennedy A, Gruen ML, Gutierrez DA, Surmi BK, Orr JS, Webb CD, Hasty AH.

PLoS One. 2012;7(2):e31508. doi: 10.1371/journal.pone.0031508. Epub 2012 Feb 16.

23.

Haematopoietic leptin receptor deficiency does not affect macrophage accumulation in adipose tissue or systemic insulin sensitivity.

Gutierrez DA, Hasty AH.

J Endocrinol. 2012 Mar;212(3):343-51. doi: 10.1530/JOE-11-0338. Epub 2011 Dec 22.

24.

Recombinant rubistatin (r-Rub), an MVD disintegrin, inhibits cell migration and proliferation, and is a strong apoptotic inducer of the human melanoma cell line SK-Mel-28.

Carey CM, Bueno R, Gutierrez DA, Petro C, Lucena SE, Sanchez EE, Soto JG.

Toxicon. 2012 Feb;59(2):241-8. doi: 10.1016/j.toxicon.2011.12.002. Epub 2011 Dec 13.

25.

Aberrant accumulation of undifferentiated myeloid cells in the adipose tissue of CCR2-deficient mice delays improvements in insulin sensitivity.

Gutierrez DA, Kennedy A, Orr JS, Anderson EK, Webb CD, Gerrald WK, Hasty AH.

Diabetes. 2011 Nov;60(11):2820-9. doi: 10.2337/db11-0314. Epub 2011 Sep 16. Erratum in: Diabetes. 2012 May;61(5):1302-4.

26.

Adipose tissue recruitment of leukocytes.

Anderson EK, Gutierrez DA, Hasty AH.

Curr Opin Lipidol. 2010 Jun;21(3):172-7. doi: 10.1097/MOL.0b013e3283393867. Review.

27.

Impact of increased adipose tissue mass on inflammation, insulin resistance, and dyslipidemia.

Gutierrez DA, Puglisi MJ, Hasty AH.

Curr Diab Rep. 2009 Feb;9(1):26-32.

28.

Cervical radiculopathy: a rare symptom of giant cell arteritis.

Cordero Sánchez M, Calvo Arenillas JI, Gutierrez DA, Gutierrez Alonso JL, de Portugal Alvarez J.

Arthritis Rheum. 1983 Feb;26(2):207-9. No abstract available.

PMID:
6297512
29.

Letter: Possible role of haematophagous insects in the transmission of Type B hepatitis.

Villarejos VM, Zúñiga A, Gutiérrez DA.

Trans R Soc Trop Med Hyg. 1975;69(3):368-9. No abstract available.

PMID:
241139
30.

[STUDY OF THE ACTION OF 6-METHYLPREDNISOLONE (URBASON) ON THE PRESSOR EFFECT OF SEROTONIN].

TERRAGNO NA, GUTIERREZ DA, DOMINGUEZMIJAN C.

Arch Inst Farmacol Exp (Madr). 1963;15:45-58. Spanish. No abstract available.

PMID:
14049385

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