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Items: 19

1.

CDC7 inhibition blocks pathological TDP-43 phosphorylation and neurodegeneration.

Liachko NF, McMillan PJ, Guthrie CR, Bird TD, Leverenz JB, Kraemer BC.

Ann Neurol. 2013 Jul;74(1):39-52. doi: 10.1002/ana.23870. Epub 2013 Jul 8.

2.

Dopamine D2 receptor antagonism suppresses tau aggregation and neurotoxicity.

McCormick AV, Wheeler JM, Guthrie CR, Liachko NF, Kraemer BC.

Biol Psychiatry. 2013 Mar 1;73(5):464-71. doi: 10.1016/j.biopsych.2012.08.027. Epub 2012 Nov 7.

3.

Potential neuroprotective strategies against tauopathy.

Wheeler JM, Guthrie CR, Kraemer BC.

Biochem Soc Trans. 2012 Aug;40(4):656-60. doi: 10.1042/BST20120017.

4.

Monoubiquitination promotes calpain cleavage of the protein phosphatase 2A (PP2A) regulatory subunit α4, altering PP2A stability and microtubule-associated protein phosphorylation.

Watkins GR, Wang N, Mazalouskas MD, Gomez RJ, Guthrie CR, Kraemer BC, Schweiger S, Spiller BW, Wadzinski BE.

J Biol Chem. 2012 Jul 13;287(29):24207-15. doi: 10.1074/jbc.M112.368613. Epub 2012 May 21.

5.

MSUT2 is a determinant of susceptibility to tau neurotoxicity.

Guthrie CR, Greenup L, Leverenz JB, Kraemer BC.

Hum Mol Genet. 2011 May 15;20(10):1989-99. doi: 10.1093/hmg/ddr079. Epub 2011 Feb 25.

6.

Proteasome inhibition drives HDAC6-dependent recruitment of tau to aggresomes.

Guthrie CR, Kraemer BC.

J Mol Neurosci. 2011 Sep;45(1):32-41. doi: 10.1007/s12031-011-9502-x. Epub 2011 Feb 22.

7.

Phosphorylation promotes neurotoxicity in a Caenorhabditis elegans model of TDP-43 proteinopathy.

Liachko NF, Guthrie CR, Kraemer BC.

J Neurosci. 2010 Dec 1;30(48):16208-19. doi: 10.1523/JNEUROSCI.2911-10.2010.

8.

The role of MSUT-2 in tau neurotoxicity: a target for neuroprotection in tauopathy?

Wheeler JM, Guthrie CR, Kraemer BC.

Biochem Soc Trans. 2010 Aug;38(4):973-6. doi: 10.1042/BST0380973. Review.

9.

SUT-2 potentiates tau-induced neurotoxicity in Caenorhabditis elegans.

Guthrie CR, Schellenberg GD, Kraemer BC.

Hum Mol Genet. 2009 May 15;18(10):1825-38. doi: 10.1093/hmg/ddp099. Epub 2009 Mar 9.

10.

Differential agonist-mediated internalization of the human 5-hydroxytryptamine 7 receptor isoforms.

Guthrie CR, Murray AT, Franklin AA, Hamblin MW.

J Pharmacol Exp Ther. 2005 Jun;313(3):1003-10. Epub 2005 Feb 16.

PMID:
15716386
11.

Cloning of the mouse 5-HT6 serotonin receptor and mutagenesis studies of the third cytoplasmic loop.

Kohen R, Fashingbauer LA, Heidmann DE, Guthrie CR, Hamblin MW.

Brain Res Mol Brain Res. 2001 Jun 20;90(2):110-7.

PMID:
11406289
12.

Gs protein-coupled serotonin receptors: receptor isoforms and functional differences.

Hamblin MW, Guthrie CR, Kohen R, Heidmann DE.

Ann N Y Acad Sci. 1998 Dec 15;861:31-7. Review.

PMID:
9928236
13.

Two novel brain-specific splice variants of the murine Cbeta gene of cAMP-dependent protein kinase.

Guthrie CR, Skâlhegg BS, McKnight GS.

J Biol Chem. 1997 Nov 21;272(47):29560-5.

14.

Choledochal cyst in the adult.

Stain SC, Guthrie CR, Yellin AE, Donovan AJ.

Ann Surg. 1995 Aug;222(2):128-33.

15.

Surgical treatment of recurrent pyogenic cholangitis.

Stain SC, Incarbone R, Guthrie CR, Ralls PW, Rivera-Lara S, Parekh D, Yellin AE.

Arch Surg. 1995 May;130(5):527-32; discussion 532-3.

PMID:
7748092
16.

Spontaneous aortocaval fistula.

Potyk DK, Guthrie CR.

Ann Emerg Med. 1995 Mar;25(3):424-7.

PMID:
7864488
17.

Calcium/calmodulin-dependent protein kinase types II and IV differentially regulate CREB-dependent gene expression.

Matthews RP, Guthrie CR, Wailes LM, Zhao X, Means AR, McKnight GS.

Mol Cell Biol. 1994 Sep;14(9):6107-16.

18.

Biochemical mechanisms of laser vascular tissue fusion.

Guthrie CR, Murray LW, Kopchok GE, Rosenbaum D, White RA.

J Invest Surg. 1991;4(1):3-12. Review.

PMID:
1863584
19.

Alterations in biochemistry of laser-fused vascular tissue.

Guthrie CR, Murray LW, Kopchok GE, Rosenbaum D, White RA.

Curr Surg. 1990 Jul-Aug;47(4):258-62. No abstract available.

PMID:
2397643

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