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Items: 1 to 50 of 62

1.

NK cells clear α-synuclein and the depletion of NK cells exacerbates synuclein pathology in a mouse model of α-synucleinopathy.

Earls RH, Menees KB, Chung J, Gutekunst CA, Lee HJ, Hazim MG, Rada B, Wood LB, Lee JK.

Proc Natl Acad Sci U S A. 2020 Jan 3. pii: 201909110. doi: 10.1073/pnas.1909110117. [Epub ahead of print]

PMID:
31900358
2.

Intrastriatal injection of preformed alpha-synuclein fibrils alters central and peripheral immune cell profiles in non-transgenic mice.

Earls RH, Menees KB, Chung J, Barber J, Gutekunst CA, Hazim MG, Lee JK.

J Neuroinflammation. 2019 Dec 3;16(1):250. doi: 10.1186/s12974-019-1636-8.

3.

A Machine Learning Approach to Characterize the Modulation of the Hippocampal Rhythms Via Optogenetic Stimulation of the Medial Septum.

Park SE, Laxpati NG, Gutekunst CA, Connolly MJ, Tung J, Berglund K, Mahmoudi B, Gross RE.

Int J Neural Syst. 2019 Dec;29(10):1950020. doi: 10.1142/S0129065719500205. Epub 2019 Jun 27.

PMID:
31505977
4.

Comparison of Two-Dimensional and Three-Dimensional Radiographs Using Clinically Relevant Parameters.

Schmidt JC, Gutekunst CJ, Dagassan-Berndt D, Schmidlin PR, Walter C.

Dent J (Basel). 2019 May 1;7(2). pii: E50. doi: 10.3390/dj7020050.

5.

Step-function luminopsins for bimodal prolonged neuromodulation.

Berglund K, Fernandez AM, Gutekunst CN, Hochgeschwender U, Gross RE.

J Neurosci Res. 2020 Mar;98(3):422-436. doi: 10.1002/jnr.24424. Epub 2019 Apr 7.

PMID:
30957296
6.

C3 Transferase Gene Therapy for Continuous RhoA Inhibition.

Santiago-Lopez AJ, Gutekunst CA, Gross RE.

Methods Mol Biol. 2018;1821:267-281. doi: 10.1007/978-1-4939-8612-5_19.

PMID:
30062419
7.

Traditional or regenerative periodontal surgery?-a comparison of the publications between two periodontal journals over time.

Staubli N, Schmidt JC, Buset SL, Gutekunst CJ, Rodriguez FR, Schmidlin PR, Walter C.

Clin Oral Investig. 2018 Jan;22(1):29-46. doi: 10.1007/s00784-017-2159-2. Epub 2017 Aug 7. Review.

PMID:
28785813
8.

C3 transferase gene therapy for continuous conditional RhoA inhibition.

Gutekunst CA, Tung JK, McDougal ME, Gross RE.

Neuroscience. 2016 Dec 17;339:308-318. doi: 10.1016/j.neuroscience.2016.10.022. Epub 2016 Oct 13.

9.

Behavioral analysis of the huntingtin-associated protein 1 ortholog trak-1 in Caenorhabditis elegans.

Norflus F, Bu J, Guyton E, Gutekunst CA.

J Neurosci Res. 2016 Sep;94(9):850-6. doi: 10.1002/jnr.23756. Epub 2016 Jun 19.

10.

Bioluminescence imaging in live cells and animals.

Tung JK, Berglund K, Gutekunst CA, Hochgeschwender U, Gross RE.

Neurophotonics. 2016 Apr;3(2):025001. doi: 10.1117/1.NPh.3.2.025001. Epub 2016 Apr 5.

11.
12.

Effects of fibroblast transplantation into the internal pallidum on levodopa-induced dyskinesias in parkinsonian non-human primates.

Singh A, Gutekunst CA, Uthayathas S, Finberg JP, Mewes K, Gross RE, Papa SM, Feld Y.

Neurosci Bull. 2015 Dec;31(6):705-13. doi: 10.1007/s12264-015-1559-z. Epub 2015 Sep 15.

13.

Real-time in vivo optogenetic neuromodulation and multielectrode electrophysiologic recording with NeuroRighter.

Laxpati NG, Mahmoudi B, Gutekunst CA, Newman JP, Zeller-Townson R, Gross RE.

Front Neuroeng. 2014 Oct 29;7:40. doi: 10.3389/fneng.2014.00040. eCollection 2014.

14.

Deep brain stimulation macroelectrodes compared to multiple microelectrodes in rat hippocampus.

Arcot Desai S, Gutekunst CA, Potter SM, Gross RE.

Front Neuroeng. 2014 Jun 12;7:16. doi: 10.3389/fneng.2014.00016. eCollection 2014.

15.

Plexin a4 expression in adult rat cranial nerves.

Gutekunst CA, Gross RE.

J Chem Neuroanat. 2014 Nov;61-62:13-9. doi: 10.1016/j.jchemneu.2014.06.003. Epub 2014 Jun 23.

16.

Inhibition of the Rho signaling pathway improves neurite outgrowth and neuronal differentiation of mouse neural stem cells.

Gu H, Yu SP, Gutekunst CA, Gross RE, Wei L.

Int J Physiol Pathophysiol Pharmacol. 2013;5(1):11-20. Epub 2013 Mar 8.

17.

Analyzing neuronal activation with macroelectrode vs. microelectrode array stimulation.

Desai SA, Gutekunst CA, Potter SM, Gross RE.

Conf Proc IEEE Eng Med Biol Soc. 2012;2012:4144-7. doi: 10.1109/EMBC.2012.6346879.

PMID:
23366840
18.

PlexinA4 distribution in the adult rat spinal cord and dorsal root ganglia.

Gutekunst CA, Stewart EN, Franz CK, English AW, Gross RE.

J Chem Neuroanat. 2012 May;44(1):1-13. doi: 10.1016/j.jchemneu.2012.03.002. Epub 2012 Mar 23.

19.

Spontaneous and evoked high-frequency oscillations in the tetanus toxin model of epilepsy.

Rolston JD, Laxpati NG, Gutekunst CA, Potter SM, Gross RE.

Epilepsia. 2010 Nov;51(11):2289-96. doi: 10.1111/j.1528-1167.2010.02753.x. Epub 2010 Oct 13.

20.

Immunohistochemical Distribution of PlexinA4 in the Adult Rat Central Nervous System.

Gutekunst CA, Stewart EN, Gross RE.

Front Neuroanat. 2010 Jul 13;4. pii: 25. doi: 10.3389/fnana.2010.00025. eCollection 2010.

21.

Expression by midbrain dopamine neurons of Sema3A and 3F receptors is associated with chemorepulsion in vitro but a mild in vivo phenotype.

Torre ER, Gutekunst CA, Gross RE.

Mol Cell Neurosci. 2010 Jun;44(2):135-53. doi: 10.1016/j.mcn.2010.03.003. Epub 2010 Mar 16.

22.

Implanted neural electrodes cause chronic, local inflammation that is correlated with local neurodegeneration.

McConnell GC, Rees HD, Levey AI, Gutekunst CA, Gross RE, Bellamkonda RV.

J Neural Eng. 2009 Oct;6(5):056003. doi: 10.1088/1741-2560/6/5/056003. Epub 2009 Aug 21.

PMID:
19700815
23.

A novel transferrin/TfR2-mediated mitochondrial iron transport system is disrupted in Parkinson's disease.

Mastroberardino PG, Hoffman EK, Horowitz MP, Betarbet R, Taylor G, Cheng D, Na HM, Gutekunst CA, Gearing M, Trojanowski JQ, Anderson M, Chu CT, Peng J, Greenamyre JT.

Neurobiol Dis. 2009 Jun;34(3):417-31. doi: 10.1016/j.nbd.2009.02.009. Epub 2009 Feb 26.

24.

A C. elegans homolog of huntingtin-associated protein 1 is expressed in chemosensory neurons and in a number of other somatic cell types.

Mercer KB, Szlam SM, Manning E, Gernert KM, Walthall WW, Benian GM, Gutekunst CA.

J Mol Neurosci. 2009 Jan;37(1):37-49. doi: 10.1007/s12031-008-9109-z. Epub 2008 Jul 1.

25.
26.

A mutation of beta -actin that alters depolymerization dynamics is associated with autosomal dominant developmental malformations, deafness, and dystonia.

Procaccio V, Salazar G, Ono S, Styers ML, Gearing M, Davila A, Jimenez R, Juncos J, Gutekunst CA, Meroni G, Fontanella B, Sontag E, Sontag JM, Faundez V, Wainer BH.

Am J Hum Genet. 2006 Jun;78(6):947-60. Epub 2006 Apr 21.

27.

Huntingtin-interacting protein HIP14 is a palmitoyl transferase involved in palmitoylation and trafficking of multiple neuronal proteins.

Huang K, Yanai A, Kang R, Arstikaitis P, Singaraja RR, Metzler M, Mullard A, Haigh B, Gauthier-Campbell C, Gutekunst CA, Hayden MR, El-Husseini A.

Neuron. 2004 Dec 16;44(6):977-86.

28.

Anti-inflammatory treatment with acetylsalicylate or rofecoxib is not neuroprotective in Huntington's disease transgenic mice.

Norflus F, Nanje A, Gutekunst CA, Shi G, Cohen J, Bejarano M, Fox J, Ferrante RJ, Hersch SM.

Neurobiol Dis. 2004 Nov;17(2):319-25.

PMID:
15474369
29.

A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease.

Goehler H, Lalowski M, Stelzl U, Waelter S, Stroedicke M, Worm U, Droege A, Lindenberg KS, Knoblich M, Haenig C, Herbst M, Suopanki J, Scherzinger E, Abraham C, Bauer B, Hasenbank R, Fritzsche A, Ludewig AH, Büssow K, Coleman SH, Gutekunst CA, Landwehrmeyer BG, Lehrach H, Wanker EE.

Mol Cell. 2004 Sep 24;15(6):853-65. Erratum in: Mol Cell. 2005 Jul 22;19(2):287. Buessow, Konrad [corrected to Büssow, Konrad].

30.

Long-term lentiviral-mediated expression of ciliary neurotrophic factor in the striatum of Huntington's disease transgenic mice.

Zala D, Bensadoun JC, Pereira de Almeida L, Leavitt BR, Gutekunst CA, Aebischer P, Hayden MR, Déglon N.

Exp Neurol. 2004 Jan;185(1):26-35.

PMID:
14697316
31.

Mast cells exert effects outside the central nervous system to influence experimental allergic encephalomyelitis disease course.

Tanzola MB, Robbie-Ryan M, Gutekunst CA, Brown MA.

J Immunol. 2003 Oct 15;171(8):4385-91.

32.

Disruption of the endocytic protein HIP1 results in neurological deficits and decreased AMPA receptor trafficking.

Metzler M, Li B, Gan L, Georgiou J, Gutekunst CA, Wang Y, Torre E, Devon RS, Oh R, Legendre-Guillemin V, Rich M, Alvarez C, Gertsenstein M, McPherson PS, Nagy A, Wang YT, Roder JC, Raymond LA, Hayden MR.

EMBO J. 2003 Jul 1;22(13):3254-66.

33.

Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease.

Slow EJ, van Raamsdonk J, Rogers D, Coleman SH, Graham RK, Deng Y, Oh R, Bissada N, Hossain SM, Yang YZ, Li XJ, Simpson EM, Gutekunst CA, Leavitt BR, Hayden MR.

Hum Mol Genet. 2003 Jul 1;12(13):1555-67.

PMID:
12812983
34.

A protocol for isolation and biochemical characterization of stigmoid bodies from rat brain.

Torre ER, Coleman S, Yi H, Gutekunst CA.

J Neurosci Methods. 2003 May 30;125(1-2):27-32.

PMID:
12763227
35.

Stigmoid bodies contain type I receptor proteins SorLA/LR11 and sortilin: new perspectives on their function.

Gutekunst CA, Torre ER, Sheng Z, Yi H, Coleman SH, Riedel IB, Bujo H.

J Histochem Cytochem. 2003 Jun;51(6):841-52.

PMID:
12754295
36.

HIP14, a novel ankyrin domain-containing protein, links huntingtin to intracellular trafficking and endocytosis.

Singaraja RR, Hadano S, Metzler M, Givan S, Wellington CL, Warby S, Yanai A, Gutekunst CA, Leavitt BR, Yi H, Fichter K, Gan L, McCutcheon K, Chopra V, Michel J, Hersch SM, Ikeda JE, Hayden MR.

Hum Mol Genet. 2002 Nov 1;11(23):2815-28.

PMID:
12393793
37.

Aggregation of actin and cofilin in identical twins with juvenile-onset dystonia.

Gearing M, Juncos JL, Procaccio V, Gutekunst CA, Marino-Rodriguez EM, Gyure KA, Ono S, Santoianni R, Krawiecki NS, Wallace DC, Wainer BH.

Ann Neurol. 2002 Oct;52(4):465-76.

38.

Caspase cleavage of mutant huntingtin precedes neurodegeneration in Huntington's disease.

Wellington CL, Ellerby LM, Gutekunst CA, Rogers D, Warby S, Graham RK, Loubser O, van Raamsdonk J, Singaraja R, Yang YZ, Gafni J, Bredesen D, Hersch SM, Leavitt BR, Roy S, Nicholson DW, Hayden MR.

J Neurosci. 2002 Sep 15;22(18):7862-72.

39.

Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines.

Panov AV, Gutekunst CA, Leavitt BR, Hayden MR, Burke JR, Strittmatter WJ, Greenamyre JT.

Nat Neurosci. 2002 Aug;5(8):731-6.

PMID:
12089530
40.

Targeted disruption of Huntingtin-associated protein-1 (Hap1) results in postnatal death due to depressed feeding behavior.

Chan EY, Nasir J, Gutekunst CA, Coleman S, Maclean A, Maas A, Metzler M, Gertsenstein M, Ross CA, Nagy A, Hayden MR.

Hum Mol Genet. 2002 Apr 15;11(8):945-59.

PMID:
11971876
41.

Early phenotypes that presage late-onset neurodegenerative disease allow testing of modifiers in Hdh CAG knock-in mice.

Wheeler VC, Gutekunst CA, Vrbanac V, Lebel LA, Schilling G, Hersch S, Friedlander RM, Gusella JF, Vonsattel JP, Borchelt DR, MacDonald ME.

Hum Mol Genet. 2002 Mar 15;11(6):633-40.

PMID:
11912178
42.

Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi.

Gervais FG, Singaraja R, Xanthoudakis S, Gutekunst CA, Leavitt BR, Metzler M, Hackam AS, Tam J, Vaillancourt JP, Houtzager V, Rasper DM, Roy S, Hayden MR, Nicholson DW.

Nat Cell Biol. 2002 Feb;4(2):95-105.

PMID:
11788820
43.

A novel procedure for pre-embedding double immunogold-silver labeling at the ultrastructural level.

Yi H, Leunissen J, Shi G, Gutekunst C, Hersch S.

J Histochem Cytochem. 2001 Mar;49(3):279-84.

PMID:
11181730
44.

Huntingtin interacting protein 1 induces apoptosis via a novel caspase-dependent death effector domain.

Hackam AS, Yassa AS, Singaraja R, Metzler M, Gutekunst CA, Gan L, Warby S, Wellington CL, Vaillancourt J, Chen N, Gervais FG, Raymond L, Nicholson DW, Hayden MR.

J Biol Chem. 2000 Dec 29;275(52):41299-308.

45.

Recent advances in Huntington's disease.

Gutekunst CA, Norflus F, Hersch SM.

Curr Opin Neurol. 2000 Aug;13(4):445-50. Review.

PMID:
10970063
46.

Mast cells are essential for early onset and severe disease in a murine model of multiple sclerosis.

Secor VH, Secor WE, Gutekunst CA, Brown MA.

J Exp Med. 2000 Mar 6;191(5):813-22.

47.

Long glutamine tracts cause nuclear localization of a novel form of huntingtin in medium spiny striatal neurons in HdhQ92 and HdhQ111 knock-in mice.

Wheeler VC, White JK, Gutekunst CA, Vrbanac V, Weaver M, Li XJ, Li SH, Yi H, Vonsattel JP, Gusella JF, Hersch S, Auerbach W, Joyner AL, MacDonald ME.

Hum Mol Genet. 2000 Mar 1;9(4):503-13.

PMID:
10699173
48.

Huntington aggregates may not predict neuronal death in Huntington's disease.

Kuemmerle S, Gutekunst CA, Klein AM, Li XJ, Li SH, Beal MF, Hersch SM, Ferrante RJ.

Ann Neurol. 1999 Dec;46(6):842-9.

PMID:
10589536
49.

Evidence for both the nucleus and cytoplasm as subcellular sites of pathogenesis in Huntington's disease in cell culture and in transgenic mice expressing mutant huntingtin.

Hackam AS, Hodgson JG, Singaraja R, Zhang T, Gan L, Gutekunst CA, Hersch SM, Hayden MR.

Philos Trans R Soc Lond B Biol Sci. 1999 Jun 29;354(1386):1047-55. Review.

50.

A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration.

Hodgson JG, Agopyan N, Gutekunst CA, Leavitt BR, LePiane F, Singaraja R, Smith DJ, Bissada N, McCutcheon K, Nasir J, Jamot L, Li XJ, Stevens ME, Rosemond E, Roder JC, Phillips AG, Rubin EM, Hersch SM, Hayden MR.

Neuron. 1999 May;23(1):181-92.

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