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Items: 30


IL-13-induced intestinal secretory epithelial cell antigen passages are required for IgE-mediated food-induced anaphylaxis.

Noah TK, Knoop KA, McDonald KG, Gustafsson JK, Waggoner L, Vanoni S, Batie M, Arora K, Naren AP, Wang YH, Lukacs NW, Munitz A, Helmrath MA, Mahe MM, Newberry RD, Hogan SP.

J Allergy Clin Immunol. 2019 Jun 5. pii: S0091-6749(19)30747-X. doi: 10.1016/j.jaci.2019.04.030. [Epub ahead of print]


Interleukin 4 induces rapid mucin transport, increases mucus thickness and quality and decreases colitis and Citrobacter rodentium in contact with epithelial cells.

Sharba S, Navabi N, Padra M, Persson JA, Quintana-Hayashi MP, Gustafsson JK, Szeponik L, Venkatakrishnan V, Sjöling Å, Nilsson S, Quiding-Järbrink M, Johansson MEV, Linden SK.

Virulence. 2019 Dec;10(1):97-117. doi: 10.1080/21505594.2019.1573050.


Predicting Risk of Postoperative Disease Recurrence in Crohn's Disease: Patients With Indolent Crohn's Disease Have Distinct Whole Transcriptome Profiles at the Time of First Surgery.

Cushing KC, Mclean R, McDonald KG, Gustafsson JK, Knoop KA, Kulkarni DH, Sartor RB, Newberry RD.

Inflamm Bowel Dis. 2019 Jan 1;25(1):180-193. doi: 10.1093/ibd/izy228.


Goblet cell associated antigen passages are inhibited during Salmonella typhimurium infection to prevent pathogen dissemination and limit responses to dietary antigens.

Kulkarni DH, McDonald KG, Knoop KA, Gustafsson JK, Kozlowski KM, Hunstad DA, Miller MJ, Newberry RD.

Mucosal Immunol. 2018 Jul;11(4):1103-1113. doi: 10.1038/s41385-018-0007-6. Epub 2018 Feb 14.


Microbial antigen encounter during a preweaning interval is critical for tolerance to gut bacteria.

Knoop KA, Gustafsson JK, McDonald KG, Kulkarni DH, Coughlin PE, McCrate S, Kim D, Hsieh CS, Hogan SP, Elson CO, Tarr PI, Newberry RD.

Sci Immunol. 2017 Dec 15;2(18). pii: eaao1314. doi: 10.1126/sciimmunol.aao1314.


CCR6 promotes steady-state mononuclear phagocyte association with the intestinal epithelium, imprinting and immune surveillance.

McDonald KG, Wheeler LW, McDole JR, Joerger S, Gustafsson JK, Kulkarni DH, Knoop KA, Williams IR, Miller MJ, Newberry RD.

Immunology. 2017 Dec;152(4):613-627. doi: 10.1111/imm.12801. Epub 2017 Aug 30.


Antibiotics promote the sampling of luminal antigens and bacteria via colonic goblet cell associated antigen passages.

Knoop KA, Gustafsson JK, McDonald KG, Kulkarni DH, Kassel R, Newberry RD.

Gut Microbes. 2017 Jul 4;8(4):400-411. doi: 10.1080/19490976.2017.1299846. Epub 2017 Mar 7.


Liver X receptor β: new player in the regulatory network of thyroid hormone and 'browning' of white fat.

Miao Y, Warner M, Gustafsson JK.

Adipocyte. 2016 Mar 17;5(2):238-42. doi: 10.1080/21623945.2016.1142634. eCollection 2016 Apr-Jun.


Hyper-osmolarity and calcium chelation: Effects on cystic fibrosis mucus.

Ermund A, Meiss LN, Gustafsson JK, Hansson GC.

Eur J Pharmacol. 2015 Oct 5;764:109-17. doi: 10.1016/j.ejphar.2015.06.051. Epub 2015 Jun 30.


New developments in goblet cell mucus secretion and function.

Birchenough GM, Johansson ME, Gustafsson JK, Bergström JH, Hansson GC.

Mucosal Immunol. 2015 Jul;8(4):712-9. doi: 10.1038/mi.2015.32. Epub 2015 Apr 15. Review.


Carbachol-induced colonic mucus formation requires transport via NKCC1, K⁺ channels and CFTR.

Gustafsson JK, Lindén SK, Alwan AH, Scholte BJ, Hansson GC, Sjövall H.

Pflugers Arch. 2015 Jul;467(7):1403-1415. doi: 10.1007/s00424-014-1595-y. Epub 2014 Aug 21.


The mucus and mucins of the goblet cells and enterocytes provide the first defense line of the gastrointestinal tract and interact with the immune system.

Pelaseyed T, Bergström JH, Gustafsson JK, Ermund A, Birchenough GM, Schütte A, van der Post S, Svensson F, Rodríguez-Piñeiro AM, Nyström EE, Wising C, Johansson ME, Hansson GC.

Immunol Rev. 2014 Jul;260(1):8-20. doi: 10.1111/imr.12182. Review.


Modified-chitosan/siRNA nanoparticles downregulate cellular CDX2 expression and cross the gastric mucus barrier.

Sadio A, Gustafsson JK, Pereira B, Gomes CP, Hansson GC, David L, Pêgo AP, Almeida R.

PLoS One. 2014 Jun 12;9(6):e99449. doi: 10.1371/journal.pone.0099449. eCollection 2014.


Dynamic changes in mucus thickness and ion secretion during Citrobacter rodentium infection and clearance.

Gustafsson JK, Navabi N, Rodriguez-Piñeiro AM, Alomran AH, Premaratne P, Fernandez HR, Banerjee D, Sjövall H, Hansson GC, Lindén SK.

PLoS One. 2013 Dec 30;8(12):e84430. doi: 10.1371/journal.pone.0084430. eCollection 2013.


Mucus properties and goblet cell quantification in mouse, rat and human ileal Peyer's patches.

Ermund A, Gustafsson JK, Hansson GC, Keita AV.

PLoS One. 2013 Dec 16;8(12):e83688. doi: 10.1371/journal.pone.0083688. eCollection 2013.


Studies of mucus in mouse stomach, small intestine, and colon. I. Gastrointestinal mucus layers have different properties depending on location as well as over the Peyer's patches.

Ermund A, Schütte A, Johansson ME, Gustafsson JK, Hansson GC.

Am J Physiol Gastrointest Liver Physiol. 2013 Sep 1;305(5):G341-7. doi: 10.1152/ajpgi.00046.2013. Epub 2013 Jul 5.


Studies of mucus in mouse stomach, small intestine, and colon. II. Gastrointestinal mucus proteome reveals Muc2 and Muc5ac accompanied by a set of core proteins.

Rodríguez-Piñeiro AM, Bergström JH, Ermund A, Gustafsson JK, Schütte A, Johansson ME, Hansson GC.

Am J Physiol Gastrointest Liver Physiol. 2013 Sep 1;305(5):G348-56. doi: 10.1152/ajpgi.00047.2013. Epub 2013 Jul 5.


Carbachol-induced MUC17 endocytosis is concomitant with NHE3 internalization and CFTR membrane recruitment in enterocytes.

Pelaseyed T, Gustafsson JK, Gustafsson IJ, Ermund A, Hansson GC.

Am J Physiol Cell Physiol. 2013 Aug 15;305(4):C457-67. doi: 10.1152/ajpcell.00141.2013. Epub 2013 Jun 19.


Response to 'Altered secretion in the right colon during ulcerative colitis: is it due to disease or to 5-ASA?'.

Gustafsson JK, Sjövall H.

Neurogastroenterol Motil. 2013 May;25(5):452. doi: 10.1111/nmo.12111. Epub 2013 Mar 11. No abstract available.


Bacteria penetrate the normally impenetrable inner colon mucus layer in both murine colitis models and patients with ulcerative colitis.

Johansson ME, Gustafsson JK, Holmén-Larsson J, Jabbar KS, Xia L, Xu H, Ghishan FK, Carvalho FA, Gewirtz AT, Sjövall H, Hansson GC.

Gut. 2014 Feb;63(2):281-91. doi: 10.1136/gutjnl-2012-303207. Epub 2013 Feb 20.


Perspectives on mucus properties and formation--lessons from the biochemical world.

Ambort D, Johansson ME, Gustafsson JK, Ermund A, Hansson GC.

Cold Spring Harb Perspect Med. 2012 Nov 1;2(11). pii: a014159. doi: 10.1101/cshperspect.a014159. Review.


Ulcerative colitis patients in remission have an altered secretory capacity in the proximal colon despite macroscopically normal mucosa.

Gustafsson JK, Hansson GC, Sjövall H.

Neurogastroenterol Motil. 2012 Aug;24(8):e381-91. doi: 10.1111/j.1365-2982.2012.01958.x. Epub 2012 Jun 24.


Bicarbonate and functional CFTR channel are required for proper mucin secretion and link cystic fibrosis with its mucus phenotype.

Gustafsson JK, Ermund A, Ambort D, Johansson ME, Nilsson HE, Thorell K, Hebert H, Sjövall H, Hansson GC.

J Exp Med. 2012 Jul 2;209(7):1263-72. doi: 10.1084/jem.20120562. Epub 2012 Jun 18.


Calcium and pH-dependent packing and release of the gel-forming MUC2 mucin.

Ambort D, Johansson ME, Gustafsson JK, Nilsson HE, Ermund A, Johansson BR, Koeck PJ, Hebert H, Hansson GC.

Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):5645-50. doi: 10.1073/pnas.1120269109. Epub 2012 Mar 26.


Ex vivo measurements of mucus secretion by colon explants.

Gustafsson JK, Sjövall H, Hansson GC.

Methods Mol Biol. 2012;842:237-43. doi: 10.1007/978-1-61779-513-8_14.


An ex vivo method for studying mucus formation, properties, and thickness in human colonic biopsies and mouse small and large intestinal explants.

Gustafsson JK, Ermund A, Johansson ME, Schütte A, Hansson GC, Sjövall H.

Am J Physiol Gastrointest Liver Physiol. 2012 Feb 15;302(4):G430-8. doi: 10.1152/ajpgi.00405.2011.. Epub 2011 Dec 8.


Composition and functional role of the mucus layers in the intestine.

Johansson ME, Ambort D, Pelaseyed T, Schütte A, Gustafsson JK, Ermund A, Subramani DB, Holmén-Larsson JM, Thomsson KA, Bergström JH, van der Post S, Rodriguez-Piñeiro AM, Sjövall H, Bäckström M, Hansson GC.

Cell Mol Life Sci. 2011 Nov;68(22):3635-41. doi: 10.1007/s00018-011-0822-3. Epub 2011 Sep 25. Review.


Amygdala activation by corticosterone alters visceral and somatic pain in cycling female rats.

Gustafsson JK, Greenwood-Van Meerveld B.

Am J Physiol Gastrointest Liver Physiol. 2011 Jun;300(6):G1080-5. doi: 10.1152/ajpgi.00349.2010. Epub 2011 Mar 31.


Bacteria penetrate the inner mucus layer before inflammation in the dextran sulfate colitis model.

Johansson ME, Gustafsson JK, Sjöberg KE, Petersson J, Holm L, Sjövall H, Hansson GC.

PLoS One. 2010 Aug 18;5(8):e12238. doi: 10.1371/journal.pone.0012238.


Cooperative interactions of steroid hormone receptors with their cognate response elements.

Tsai MJ, Tsai SY, Klein-Hitpass L, Bagchi M, Elliston JF, Carlstedt-Duke J, Gustafsson JA, O'Malley BW.

Cold Spring Harb Symp Quant Biol. 1988;53 Pt 2:829-33. No abstract available. Erratum in: Cold Spring Harb Symp Quant Biol. 2007;72:675. Gustafsson, J K [corrected to Gustafsson, J A].


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