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Items: 1 to 50 of 345

1.

The association between the "Plate it Up Kentucky" supermarket intervention and changes in grocery shopping practices among rural residents.

Gustafson A, Ng SW, Jilcott Pitts S.

Transl Behav Med. 2019 Oct 1;9(5):865-874. doi: 10.1093/tbm/ibz064.

PMID:
31570920
2.

Cysteine depletion targets leukemia stem cells through inhibition of electron transport complex II.

Jones CL, Stevens BM, D'Alessandro A, Culp-Hill R, Reisz JA, Pei S, Gustafson A, Khan N, DeGregori J, Pollyea DA, Jordan CT.

Blood. 2019 Jul 25;134(4):389-394. doi: 10.1182/blood.2019898114. Epub 2019 May 17.

PMID:
31101624
3.

Systems thinking as a pathway to global warming beliefs and attitudes through an ecological worldview.

Ballew MT, Goldberg MH, Rosenthal SA, Gustafson A, Leiserowitz A.

Proc Natl Acad Sci U S A. 2019 Apr 23;116(17):8214-8219. doi: 10.1073/pnas.1819310116. Epub 2019 Apr 8.

4.
5.

Community-Wide Efforts to Improve the Consumer Food Environment and Physical Activity Resources in Rural Kentucky.

Gustafson A, McGladrey M, Stephenson T, Kurzynske J, Mullins J, Peritore N, Cardarelli K, Vail A.

Prev Chronic Dis. 2019 Jan 17;16:E07. doi: 10.5888/pcd16.180322. Erratum in: Prev Chronic Dis. 2019 Feb 14;16:E18.

6.

Aromatic Donor-Acceptor Interaction-Based Co(III)-salen Self-Assemblies and Their Applications in Asymmetric Ring Opening of Epoxides.

Liang J, Soucie LN, Blechschmidt DR, Yoder A, Gustafson A, Liu Y.

Org Lett. 2019 Jan 18;21(2):513-518. doi: 10.1021/acs.orglett.8b03824. Epub 2018 Dec 28.

PMID:
30592622
7.
8.

Online grocery shopping: promise and pitfalls for healthier food and beverage purchases.

Jilcott Pitts SB, Ng SW, Blitstein JL, Gustafson A, Niculescu M.

Public Health Nutr. 2018 Dec;21(18):3360-3376. doi: 10.1017/S1368980018002409. Epub 2018 Oct 19. Review.

PMID:
30338751
9.

Pharmacological Induction of RAS-GTP Confers RAF Inhibitor Sensitivity in KRAS Mutant Tumors.

Yen I, Shanahan F, Merchant M, Orr C, Hunsaker T, Durk M, La H, Zhang X, Martin SE, Lin E, Chan J, Yu Y, Amin D, Neve RM, Gustafson A, Venkatanarayan A, Foster SA, Rudolph J, Klijn C, Malek S.

Cancer Cell. 2018 Oct 8;34(4):611-625.e7. doi: 10.1016/j.ccell.2018.09.002.

10.

Identification of the minimal bacterial 2'-deoxy-7-amido-7-deazaguanine synthesis machinery.

Yuan Y, Hutinet G, Valera JG, Hu J, Hillebrand R, Gustafson A, Iwata-Reuyl D, Dedon PC, de Crécy-Lagard V.

Mol Microbiol. 2018 Nov;110(3):469-483. doi: 10.1111/mmi.14113. Epub 2018 Oct 12.

11.

Bones in human CYP26B1 deficiency and rats with hypervitaminosis A phenocopy Vegfa overexpression.

Lind T, Lugano R, Gustafson AM, Norgård M, van Haeringen A, Dimberg A, Melhus H, Robertson SP, Andersson G.

Bone Rep. 2018 Jun 21;9:27-36. doi: 10.1016/j.bonr.2018.06.006. eCollection 2018 Dec.

12.

The Effect of Lipopolysaccharide-Induced Experimental Bovine Mastitis on Clinical Parameters, Inflammatory Markers, and the Metabolome: A Kinetic Approach.

Johnzon CF, Dahlberg J, Gustafson AM, Waern I, Moazzami AA, Östensson K, Pejler G.

Front Immunol. 2018 Jun 25;9:1487. doi: 10.3389/fimmu.2018.01487. eCollection 2018.

13.

Development of a mass spectrometry-based tryptophan 2, 3-dioxygenase assay using liver cytosol from multiple species.

Wang J, Takahashi RH, DeMent K, Gustafson A, Kenny JR, Wong SG, Yan Z.

Anal Biochem. 2018 Sep 1;556:85-90. doi: 10.1016/j.ab.2018.06.025. Epub 2018 Jun 28.

PMID:
29959909
14.

Aminoisoxazoles as Potent Inhibitors of Tryptophan 2,3-Dioxygenase 2 (TDO2).

Pei Z, Mendonca R, Gazzard L, Pastor R, Goon L, Gustafson A, VanderPorten E, Hatzivassiliou G, Dement K, Cass R, Yuen PW, Zhang Y, Wu G, Lin X, Liu Y, Sellers BD.

ACS Med Chem Lett. 2018 Apr 2;9(5):417-421. doi: 10.1021/acsmedchemlett.7b00427. eCollection 2018 May 10.

15.

Pregnancy and Cancer Treatment: Developing a Standardized Testing Policy and Procedure

Jagels B, Amin L, Gustafson A.

Clin J Oncol Nurs. 2018 Apr 1;22(2):218-219. doi: 10.1188/18.CJON.218-219.

PMID:
29547613
16.

Pregnancy Screening in Patients With Cancer.

Gustafson AM, Goldfrank DJ, Dunson WA, Mulkerin DL, Caires RL, Eaton KD.

J Natl Compr Canc Netw. 2018 Jan;16(1):99-103. doi: 10.6004/jnccn.2017.7059. No abstract available.

PMID:
29295884
17.

Direct Effects of the Home, School, and Consumer Food Environments on the Association between Food Purchasing Patterns and Dietary Intake among Rural Adolescents in Kentucky and North Carolina, 2017.

Gustafson A, Jilcott Pitts S, McDonald J, Ford H, Connelly P, Gillespie R, Liu E, Bush H, Brancato C, Babatande T, Mullins J.

Int J Environ Res Public Health. 2017 Oct 21;14(10). pii: E1255. doi: 10.3390/ijerph14101255.

18.

Marketing Strategies to Encourage Rural Residents of High-Obesity Counties to Buy Fruits and Vegetables in Grocery Stores.

Liu E, Stephenson T, Houlihan J, Gustafson A.

Prev Chronic Dis. 2017 Oct 12;14:E94. doi: 10.5888/pcd14.170109.

19.

Selective Inhibitors of Dual Leucine Zipper Kinase (DLK, MAP3K12) with Activity in a Model of Alzheimer's Disease.

Patel S, Meilandt WJ, Erickson RI, Chen J, Deshmukh G, Estrada AA, Fuji RN, Gibbons P, Gustafson A, Harris SF, Imperio J, Liu W, Liu X, Liu Y, Lyssikatos JP, Ma C, Yin J, Lewcock JW, Siu M.

J Med Chem. 2017 Oct 12;60(19):8083-8102. doi: 10.1021/acs.jmedchem.7b00843. Epub 2017 Sep 20.

PMID:
28929759
20.

A Community-Based Marketing Campaign at Farmers Markets to Encourage Fruit and Vegetable Purchases in Rural Counties With High Rates of Obesity, Kentucky, 2015-2016.

DeWitt E, McGladrey M, Liu E, Peritore N, Webber K, Butterworth B, Vail A, Gustafson A.

Prev Chronic Dis. 2017 Aug 31;14:E72. doi: 10.5888/pcd14.170010.

21.

Loss of dual leucine zipper kinase signaling is protective in animal models of neurodegenerative disease.

Le Pichon CE, Meilandt WJ, Dominguez S, Solanoy H, Lin H, Ngu H, Gogineni A, Sengupta Ghosh A, Jiang Z, Lee SH, Maloney J, Gandham VD, Pozniak CD, Wang B, Lee S, Siu M, Patel S, Modrusan Z, Liu X, Rudhard Y, Baca M, Gustafson A, Kaminker J, Carano RAD, Huang EJ, Foreman O, Weimer R, Scearce-Levie K, Lewcock JW.

Sci Transl Med. 2017 Aug 16;9(403). pii: eaag0394. doi: 10.1126/scitranslmed.aag0394.

22.

Recovery of bovine Babesia spp. after long-term cryostorage and comparison of bovine donor erythrocytes and serum.

Alhaboubi A, He L, McCormack K, Gustafson A, Holman PJ.

Vet Parasitol. 2017 Aug 30;243:109-114. doi: 10.1016/j.vetpar.2017.06.017. Epub 2017 Jun 20.

PMID:
28807277
23.

Examining Key Stakeholder and Community Residents' Understanding of Environmental Influences to Inform Place-Based Interventions to Reduce Obesity in Rural Communities, Kentucky 2015.

Gustafson A, McGladrey M, Liu E, Peritore N, Webber K, Butterworth B, Vail A.

J Rural Health. 2018 Sep;34(4):388-395. doi: 10.1111/jrh.12254. Epub 2017 Jul 7.

PMID:
28685866
25.

From a novel HTS hit to potent, selective, and orally bioavailable KDM5 inhibitors.

Liang J, Labadie S, Zhang B, Ortwine DF, Patel S, Vinogradova M, Kiefer JR, Mauer T, Gehling VS, Harmange JC, Cummings R, Lai T, Liao J, Zheng X, Liu Y, Gustafson A, Van der Porten E, Mao W, Liederer BM, Deshmukh G, An L, Ran Y, Classon M, Trojer P, Dragovich PS, Murray L.

Bioorg Med Chem Lett. 2017 Jul 1;27(13):2974-2981. doi: 10.1016/j.bmcl.2017.05.016. Epub 2017 May 5.

PMID:
28512031
26.

A novel NMDA receptor positive allosteric modulator that acts via the transmembrane domain.

Wang TM, Brown BM, Deng L, Sellers BD, Lupardus PJ, Wallweber HJA, Gustafson A, Wong E, Volgraf M, Schwarz JB, Hackos DH, Hanson JE.

Neuropharmacology. 2017 Jul 15;121:204-218. doi: 10.1016/j.neuropharm.2017.04.041. Epub 2017 Apr 27.

27.

The combined action of mast cell chymase, tryptase and carboxypeptidase A3 protects against melanoma colonization of the lung.

Grujic M, Paivandy A, Gustafson AM, Thomsen AR, Öhrvik H, Pejler G.

Oncotarget. 2017 Apr 11;8(15):25066-25079. doi: 10.18632/oncotarget.15339.

28.

Mechanism and catalytic strategy of the prokaryotic-specific GTP cyclohydrolase-IB.

Paranagama N, Bonnett SA, Alvarez J, Luthra A, Stec B, Gustafson A, Iwata-Reuyl D, Swairjo MA.

Biochem J. 2017 Mar 7;474(6):1017-1039. doi: 10.1042/BCJ20161025.

29.

Tryptase-catalyzed core histone truncation: A novel epigenetic regulatory mechanism in mast cells.

Melo FR, Wallerman O, Paivandy A, Calounova G, Gustafson AM, Sabari BR, Zabucchi G, Allis CD, Pejler G.

J Allergy Clin Immunol. 2017 Aug;140(2):474-485. doi: 10.1016/j.jaci.2016.11.044. Epub 2017 Jan 17.

30.

Reducing Patient Uncertainty: Implementation of a Shared Decision-Making Process Enhances Treatment Quality and Provider Communication.

Gustafson A.

Clin J Oncol Nurs. 2017 Feb 1;21(1):113-115. doi: 10.1188/17.CJON.113-115. Review.

PMID:
28107332
31.

Increased Bone Mass in Female Mice Lacking Mast Cell Chymase.

Lind T, Gustafson AM, Calounova G, Hu L, Rasmusson A, Jonsson KB, Wernersson S, Åbrink M, Andersson G, Larsson S, Melhus H, Pejler G.

PLoS One. 2016 Dec 9;11(12):e0167964. doi: 10.1371/journal.pone.0167964. eCollection 2016.

32.

Mast cells promote melanoma colonization of lungs.

Öhrvik H, Grujic M, Waern I, Gustafson AM, Ernst N, Roers A, Hartmann K, Pejler G.

Oncotarget. 2016 Oct 18;7(42):68990-69001. doi: 10.18632/oncotarget.11837.

33.

Design and evaluation of 1,7-naphthyridones as novel KDM5 inhibitors.

Labadie SS, Dragovich PS, Cummings RT, Deshmukh G, Gustafson A, Han N, Harmange JC, Kiefer JR, Li Y, Liang J, Liederer BM, Liu Y, Manieri W, Mao W, Murray L, Ortwine DF, Trojer P, VanderPorten E, Vinogradova M, Wen L.

Bioorg Med Chem Lett. 2016 Sep 15;26(18):4492-4496. doi: 10.1016/j.bmcl.2016.07.070. Epub 2016 Jul 29.

PMID:
27499454
34.

Identification of potent, selective KDM5 inhibitors.

Gehling VS, Bellon SF, Harmange JC, LeBlanc Y, Poy F, Odate S, Buker S, Lan F, Arora S, Williamson KE, Sandy P, Cummings RT, Bailey CM, Bergeron L, Mao W, Gustafson A, Liu Y, VanderPorten E, Audia JE, Trojer P, Albrecht BK.

Bioorg Med Chem Lett. 2016 Sep 1;26(17):4350-4. doi: 10.1016/j.bmcl.2016.07.026. Epub 2016 Jul 19.

PMID:
27476424
35.

Lead optimization of a pyrazolo[1,5-a]pyrimidin-7(4H)-one scaffold to identify potent, selective and orally bioavailable KDM5 inhibitors suitable for in vivo biological studies.

Liang J, Zhang B, Labadie S, Ortwine DF, Vinogradova M, Kiefer JR, Gehling VS, Harmange JC, Cummings R, Lai T, Liao J, Zheng X, Liu Y, Gustafson A, Van der Porten E, Mao W, Liederer BM, Deshmukh G, Classon M, Trojer P, Dragovich PS, Murray L.

Bioorg Med Chem Lett. 2016 Aug 15;26(16):4036-41. doi: 10.1016/j.bmcl.2016.06.078. Epub 2016 Jun 29.

PMID:
27406798
36.

An inhibitor of KDM5 demethylases reduces survival of drug-tolerant cancer cells.

Vinogradova M, Gehling VS, Gustafson A, Arora S, Tindell CA, Wilson C, Williamson KE, Guler GD, Gangurde P, Manieri W, Busby J, Flynn EM, Lan F, Kim HJ, Odate S, Cochran AG, Liu Y, Wongchenko M, Yang Y, Cheung TK, Maile TM, Lau T, Costa M, Hegde GV, Jackson E, Pitti R, Arnott D, Bailey C, Bellon S, Cummings RT, Albrecht BK, Harmange JC, Kiefer JR, Trojer P, Classon M.

Nat Chem Biol. 2016 Jul;12(7):531-8. doi: 10.1038/nchembio.2085. Epub 2016 May 23.

PMID:
27214401
37.

BMP-9 dependent pathways required for the chondrogenic differentiation of pluripotent stem cells.

Cheng A, Gustafson AR, Schaner Tooley CE, Zhang M.

Differentiation. 2016 Dec;92(5):298-305. doi: 10.1016/j.diff.2016.03.005. Epub 2016 Apr 4.

PMID:
27056281
38.

Discovery of GluN2A-Selective NMDA Receptor Positive Allosteric Modulators (PAMs): Tuning Deactivation Kinetics via Structure-Based Design.

Volgraf M, Sellers BD, Jiang Y, Wu G, Ly CQ, Villemure E, Pastor RM, Yuen PW, Lu A, Luo X, Liu M, Zhang S, Sun L, Fu Y, Lupardus PJ, Wallweber HJ, Liederer BM, Deshmukh G, Plise E, Tay S, Reynen P, Herrington J, Gustafson A, Liu Y, Dirksen A, Dietz MG, Liu Y, Wang TM, Hanson JE, Hackos D, Scearce-Levie K, Schwarz JB.

J Med Chem. 2016 Mar 24;59(6):2760-79. doi: 10.1021/acs.jmedchem.5b02010. Epub 2016 Mar 8.

PMID:
26919761
39.

Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit Function.

Hackos DH, Lupardus PJ, Grand T, Chen Y, Wang TM, Reynen P, Gustafson A, Wallweber HJ, Volgraf M, Sellers BD, Schwarz JB, Paoletti P, Sheng M, Zhou Q, Hanson JE.

Neuron. 2016 Mar 2;89(5):983-99. doi: 10.1016/j.neuron.2016.01.016. Epub 2016 Feb 11.

40.

Scaffold-Hopping and Structure-Based Discovery of Potent, Selective, And Brain Penetrant N-(1H-Pyrazol-3-yl)pyridin-2-amine Inhibitors of Dual Leucine Zipper Kinase (DLK, MAP3K12).

Patel S, Harris SF, Gibbons P, Deshmukh G, Gustafson A, Kellar T, Lin H, Liu X, Liu Y, Liu Y, Ma C, Scearce-Levie K, Ghosh AS, Shin YG, Solanoy H, Wang J, Wang B, Yin J, Siu M, Lewcock JW.

J Med Chem. 2015 Oct 22;58(20):8182-99. doi: 10.1021/acs.jmedchem.5b01072. Epub 2015 Oct 2.

PMID:
26431428
41.

Identification of orally-bioavailable antagonists of the TRPV4 ion-channel.

Wei ZL, Nguyen MT, O'Mahony DJ, Acevedo A, Zipfel S, Zhang Q, Liu L, Dourado M, Chi C, Yip V, DeFalco J, Gustafson A, Emerling DE, Kelly MG, Kincaid J, Vincent F, Duncton MA.

Bioorg Med Chem Lett. 2015 Sep 15;25(18):4011-5. doi: 10.1016/j.bmcl.2015.06.098. Epub 2015 Jul 6.

PMID:
26235950
42.

Development and Validation of a Farmers' Market Audit Tool in Rural and Urban Communities.

Byker Shanks C, Jilcott Pitts S, Gustafson A.

Health Promot Pract. 2015 Nov;16(6):859-66. doi: 10.1177/1524839915597899. Epub 2015 Jul 31.

43.

Loss of protein targeting to glycogen sensitizes human hepatocellular carcinoma cells towards glucose deprivation mediated oxidative stress and cell death.

Yang R, Zhang M, Gustafson AR, Wang E, Cole MP, Tooley CE, Cheng A.

Biosci Rep. 2015 May 1;35(3). pii: e00207. doi: 10.1042/BSR20150090.

44.

Compound Transfer by Acoustic Droplet Ejection Promotes Quality and Efficiency in Ultra-High-Throughput Screening Campaigns.

Dawes TD, Turincio R, Jones SW, Rodriguez RA, Gadiagellan D, Thana P, Clark KR, Gustafson AE, Orren L, Liimatta M, Gross DP, Maurer T, Beresini MH.

J Lab Autom. 2016 Feb;21(1):64-75. doi: 10.1177/2211068215590588. Epub 2015 Jun 15.

PMID:
26077161
45.

Discovery of dual leucine zipper kinase (DLK, MAP3K12) inhibitors with activity in neurodegeneration models.

Patel S, Cohen F, Dean BJ, De La Torre K, Deshmukh G, Estrada AA, Ghosh AS, Gibbons P, Gustafson A, Huestis MP, Le Pichon CE, Lin H, Liu W, Liu X, Liu Y, Ly CQ, Lyssikatos JP, Ma C, Scearce-Levie K, Shin YG, Solanoy H, Stark KL, Wang J, Wang B, Zhao X, Lewcock JW, Siu M.

J Med Chem. 2015 Jan 8;58(1):401-18. doi: 10.1021/jm5013984. Epub 2014 Oct 23.

PMID:
25341110
46.

Novel proteins for homocysteine biosynthesis in anaerobic microorganisms.

Rauch BJ, Gustafson A, Perona JJ.

Mol Microbiol. 2014 Dec;94(6):1330-42. doi: 10.1111/mmi.12832. Epub 2014 Nov 6.

47.

Molecular mechanisms of Alzheimer disease protection by the A673T allele of amyloid precursor protein.

Maloney JA, Bainbridge T, Gustafson A, Zhang S, Kyauk R, Steiner P, van der Brug M, Liu Y, Ernst JA, Watts RJ, Atwal JK.

J Biol Chem. 2014 Nov 7;289(45):30990-1000. doi: 10.1074/jbc.M114.589069. Epub 2014 Sep 24.

48.

Time course analysis of mechanical ventilation-induced diaphragm contractile muscle dysfunction in the rat.

Corpeno R, Dworkin B, Cacciani N, Salah H, Bergman HM, Ravara B, Vitadello M, Gorza L, Gustafson AM, Hedström Y, Petersson J, Feng HZ, Jin JP, Iwamoto H, Yagi N, Artemenko K, Bergquist J, Larsson L.

J Physiol. 2014 Sep 1;592(17):3859-80. doi: 10.1113/jphysiol.2014.277962. Epub 2014 Jul 11.

49.

Fishing for teratogens: a consortium effort for a harmonized zebrafish developmental toxicology assay.

Ball JS, Stedman DB, Hillegass JM, Zhang CX, Panzica-Kelly J, Coburn A, Enright BP, Tornesi B, Amouzadeh HR, Hetheridge M, Gustafson AL, Augustine-Rauch KA.

Toxicol Sci. 2014 May;139(1):210-9. doi: 10.1093/toxsci/kfu017. Epub 2014 Feb 4.

PMID:
24496635
50.

Farmers' market use is associated with fruit and vegetable consumption in diverse southern rural communities.

Jilcott Pitts SB, Gustafson A, Wu Q, Leah Mayo M, Ward RK, McGuirt JT, Rafferty AP, Lancaster MF, Evenson KR, Keyserling TC, Ammerman AS.

Nutr J. 2014 Jan 9;13:1. doi: 10.1186/1475-2891-13-1.

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