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Items: 16

1.

HSPA12A targets the cytoplasmic domain and affects the trafficking of the Amyloid Precursor Protein receptor SorLA.

Madsen P, Isaksen TJ, Siupka P, Tóth AE, Nyegaard M, Gustafsen C, Nielsen MS.

Sci Rep. 2019 Jan 24;9(1):611. doi: 10.1038/s41598-018-37336-6.

2.

Association between circulating proprotein convertase subtilisin/kexin type 9 levels and prognosis in patients with severe chronic kidney disease.

Rasmussen LD, Bøttcher M, Ivarsen P, Jørgensen HS, Nyegaard M, Buttenschøn H, Gustafsen C, Glerup S, Bøtker HE, Svensson M, Winther S.

Nephrol Dial Transplant. 2018 Aug 22. doi: 10.1093/ndt/gfy257. [Epub ahead of print]

PMID:
30137516
3.

Heparan sulfate proteoglycans present PCSK9 to the LDL receptor.

Gustafsen C, Olsen D, Vilstrup J, Lund S, Reinhardt A, Wellner N, Larsen T, Andersen CBF, Weyer K, Li JP, Seeberger PH, Thirup S, Madsen P, Glerup S.

Nat Commun. 2017 Sep 11;8(1):503. doi: 10.1038/s41467-017-00568-7.

4.

Increased serum levels of sortilin are associated with depression and correlated with BDNF and VEGF.

Buttenschøn HN, Demontis D, Kaas M, Elfving B, Mølgaard S, Gustafsen C, Kaerlev L, Petersen CM, Børglum AD, Mors O, Glerup S.

Transl Psychiatry. 2015 Nov 10;5:e677. doi: 10.1038/tp.2015.167.

5.

SorLA complement-type repeat domains protect the amyloid precursor protein against processing.

Mehmedbasic A, Christensen SK, Nilsson J, Rüetschi U, Gustafsen C, Poulsen AS, Rasmussen RW, Fjorback AN, Larson G, Andersen OM.

J Biol Chem. 2015 Feb 6;290(6):3359-76. doi: 10.1074/jbc.M114.619940. Epub 2014 Dec 18.

6.

SorCS2 regulates dopaminergic wiring and is processed into an apoptotic two-chain receptor in peripheral glia.

Glerup S, Olsen D, Vaegter CB, Gustafsen C, Sjoegaard SS, Hermey G, Kjolby M, Molgaard S, Ulrichsen M, Boggild S, Skeldal S, Fjorback AN, Nyengaard JR, Jacobsen J, Bender D, Bjarkam CR, Sørensen ES, Füchtbauer EM, Eichele G, Madsen P, Willnow TE, Petersen CM, Nykjaer A.

Neuron. 2014 Jun 4;82(5):1074-87. doi: 10.1016/j.neuron.2014.04.022.

7.

The hypercholesterolemia-risk gene SORT1 facilitates PCSK9 secretion.

Gustafsen C, Kjolby M, Nyegaard M, Mattheisen M, Lundhede J, Buttenschøn H, Mors O, Bentzon JF, Madsen P, Nykjaer A, Glerup S.

Cell Metab. 2014 Feb 4;19(2):310-8. doi: 10.1016/j.cmet.2013.12.006.

8.

SorLA controls neurotrophic activity by sorting of GDNF and its receptors GFRα1 and RET.

Glerup S, Lume M, Olsen D, Nyengaard JR, Vaegter CB, Gustafsen C, Christensen EI, Kjolby M, Hay-Schmidt A, Bender D, Madsen P, Saarma M, Nykjaer A, Petersen CM.

Cell Rep. 2013 Jan 31;3(1):186-99. doi: 10.1016/j.celrep.2012.12.011. Epub 2013 Jan 17.

9.

The pro-neurotrophin receptor sortilin is a major neuronal apolipoprotein E receptor for catabolism of amyloid-β peptide in the brain.

Carlo AS, Gustafsen C, Mastrobuoni G, Nielsen MS, Burgert T, Hartl D, Rohe M, Nykjaer A, Herz J, Heeren J, Kempa S, Petersen CM, Willnow TE.

J Neurosci. 2013 Jan 2;33(1):358-70. doi: 10.1523/JNEUROSCI.2425-12.2013.

10.

Sortilin and SorLA display distinct roles in processing and trafficking of amyloid precursor protein.

Gustafsen C, Glerup S, Pallesen LT, Olsen D, Andersen OM, Nykjær A, Madsen P, Petersen CM.

J Neurosci. 2013 Jan 2;33(1):64-71. doi: 10.1523/JNEUROSCI.2371-12.2013.

11.

Retromer binds the FANSHY sorting motif in SorLA to regulate amyloid precursor protein sorting and processing.

Fjorback AW, Seaman M, Gustafsen C, Mehmedbasic A, Gokool S, Wu C, Militz D, Schmidt V, Madsen P, Nyengaard JR, Willnow TE, Christensen EI, Mobley WB, Nykjær A, Andersen OM.

J Neurosci. 2012 Jan 25;32(4):1467-80. doi: 10.1523/JNEUROSCI.2272-11.2012.

12.

Proneurotrophin-3 may induce Sortilin-dependent death in inner ear neurons.

Tauris J, Gustafsen C, Christensen EI, Jansen P, Nykjaer A, Nyengaard JR, Teng KK, Schwarz E, Ovesen T, Madsen P, Petersen CM.

Eur J Neurosci. 2011 Feb;33(4):622-31. doi: 10.1111/j.1460-9568.2010.07556.x. Epub 2011 Jan 24.

13.

GGA autoinhibition revisited.

Cramer JF, Gustafsen C, Behrens MA, Oliveira CL, Pedersen JS, Madsen P, Petersen CM, Thirup SS.

Traffic. 2010 Feb;11(2):259-73. doi: 10.1111/j.1600-0854.2009.01017.x. Epub 2009 Nov 10.

14.

Different motifs regulate trafficking of SorCS1 isoforms.

Nielsen MS, Keat SJ, Hamati JW, Madsen P, Gutzmann JJ, Engelsberg A, Pedersen KM, Gustafsen C, Nykjaer A, Gliemann J, Hermans-Borgmeyer I, Kuhl D, Petersen CM, Hermey G.

Traffic. 2008 Jun;9(6):980-94. doi: 10.1111/j.1600-0854.2008.00731.x. Epub 2008 Feb 27.

15.

Sorting by the cytoplasmic domain of the amyloid precursor protein binding receptor SorLA.

Nielsen MS, Gustafsen C, Madsen P, Nyengaard JR, Hermey G, Bakke O, Mari M, Schu P, Pohlmann R, Dennes A, Petersen CM.

Mol Cell Biol. 2007 Oct;27(19):6842-51. Epub 2007 Jul 23.

16.

The Lotus japonicus ndx gene family is involved in nodule function and maintenance.

Grønlund M, Gustafsen C, Roussis A, Jensen D, Nielsen LP, Marcker KA, Jensen EO.

Plant Mol Biol. 2003 May;52(2):303-16.

PMID:
12856938

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