Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 58

1.

Identification of Novel α-Pyrones from Conexibacter woesei Serving as Sulfate Shuttles.

Wiker F, Konnerth M, Helmle I, Kulik A, Kaysser L, Gross H, Gust B.

ACS Chem Biol. 2019 Sep 20;14(9):1972-1980. doi: 10.1021/acschembio.9b00455. Epub 2019 Aug 27.

PMID:
31419109
2.

Caprazamycins: Biosynthesis and structure activity relationship studies.

Wiker F, Hauck N, Grond S, Gust B.

Int J Med Microbiol. 2019 Jul;309(5):319-324. doi: 10.1016/j.ijmm.2019.05.004. Epub 2019 May 24. Review.

PMID:
31138496
3.

AGOS: A Plug-and-Play Method for the Assembly of Artificial Gene Operons into Functional Biosynthetic Gene Clusters.

Basitta P, Westrich L, Rösch M, Kulik A, Gust B, Apel AK.

ACS Synth Biol. 2017 May 19;6(5):817-825. doi: 10.1021/acssynbio.6b00319. Epub 2017 Feb 20.

PMID:
28182401
4.

The Systematic Investigation of the Quorum Sensing System of the Biocontrol Strain Pseudomonas chlororaphis subsp. aurantiaca PB-St2 Unveils aurI to Be a Biosynthetic Origin for 3-Oxo-Homoserine Lactones.

Bauer JS, Hauck N, Christof L, Mehnaz S, Gust B, Gross H.

PLoS One. 2016 Nov 18;11(11):e0167002. doi: 10.1371/journal.pone.0167002. eCollection 2016.

5.

DNA affinity capturing identifies new regulators of the heterologously expressed novobiocin gene cluster in Streptomyces coelicolor M512.

Bekiesch P, Franz-Wachtel M, Kulik A, Brocker M, Forchhammer K, Gust B, Apel AK.

Appl Microbiol Biotechnol. 2016 May;100(10):4495-509. doi: 10.1007/s00253-016-7306-1. Epub 2016 Jan 21.

PMID:
26795961
6.

Minimum Information about a Biosynthetic Gene cluster.

Medema MH, Kottmann R, Yilmaz P, Cummings M, Biggins JB, Blin K, de Bruijn I, Chooi YH, Claesen J, Coates RC, Cruz-Morales P, Duddela S, Düsterhus S, Edwards DJ, Fewer DP, Garg N, Geiger C, Gomez-Escribano JP, Greule A, Hadjithomas M, Haines AS, Helfrich EJ, Hillwig ML, Ishida K, Jones AC, Jones CS, Jungmann K, Kegler C, Kim HU, Kötter P, Krug D, Masschelein J, Melnik AV, Mantovani SM, Monroe EA, Moore M, Moss N, Nützmann HW, Pan G, Pati A, Petras D, Reen FJ, Rosconi F, Rui Z, Tian Z, Tobias NJ, Tsunematsu Y, Wiemann P, Wyckoff E, Yan X, Yim G, Yu F, Xie Y, Aigle B, Apel AK, Balibar CJ, Balskus EP, Barona-Gómez F, Bechthold A, Bode HB, Borriss R, Brady SF, Brakhage AA, Caffrey P, Cheng YQ, Clardy J, Cox RJ, De Mot R, Donadio S, Donia MS, van der Donk WA, Dorrestein PC, Doyle S, Driessen AJ, Ehling-Schulz M, Entian KD, Fischbach MA, Gerwick L, Gerwick WH, Gross H, Gust B, Hertweck C, Höfte M, Jensen SE, Ju J, Katz L, Kaysser L, Klassen JL, Keller NP, Kormanec J, Kuipers OP, Kuzuyama T, Kyrpides NC, Kwon HJ, Lautru S, Lavigne R, Lee CY, Linquan B, Liu X, Liu W, Luzhetskyy A, Mahmud T, Mast Y, Méndez C, Metsä-Ketelä M, Micklefield J, Mitchell DA, Moore BS, Moreira LM, Müller R, Neilan BA, Nett M, Nielsen J, O'Gara F, Oikawa H, Osbourn A, Osburne MS, Ostash B, Payne SM, Pernodet JL, Petricek M, Piel J, Ploux O, Raaijmakers JM, Salas JA, Schmitt EK, Scott B, Seipke RF, Shen B, Sherman DH, Sivonen K, Smanski MJ, Sosio M, Stegmann E, Süssmuth RD, Tahlan K, Thomas CM, Tang Y, Truman AW, Viaud M, Walton JD, Walsh CT, Weber T, van Wezel GP, Wilkinson B, Willey JM, Wohlleben W, Wright GD, Ziemert N, Zhang C, Zotchev SB, Breitling R, Takano E, Glöckner FO.

Nat Chem Biol. 2015 Sep;11(9):625-31. doi: 10.1038/nchembio.1890. No abstract available.

7.

Mechanism of action of the uridyl peptide antibiotics: an unexpected link to a protein-protein interaction site in translocase MraY.

Rodolis MT, Mihalyi A, Ducho C, Eitel K, Gust B, Goss RJ, Bugg TD.

Chem Commun (Camb). 2014 Nov 7;50(86):13023-5. doi: 10.1039/c4cc06516f.

PMID:
25222373
8.

Multidimensional mapping of spin-exchange optical pumping in clinical-scale batch-mode 129Xe hyperpolarizers.

Nikolaou P, Coffey AM, Ranta K, Walkup LL, Gust BM, Barlow MJ, Rosen MS, Goodson BM, Chekmenev EY.

J Phys Chem B. 2014 May 8;118(18):4809-16. doi: 10.1021/jp501493k. Epub 2014 Apr 25.

9.

XeNA: an automated 'open-source' (129)Xe hyperpolarizer for clinical use.

Nikolaou P, Coffey AM, Walkup LL, Gust BM, Whiting N, Newton H, Muradyan I, Dabaghyan M, Ranta K, Moroz GD, Rosen MS, Patz S, Barlow MJ, Chekmenev EY, Goodson BM.

Magn Reson Imaging. 2014 Jun;32(5):541-50. doi: 10.1016/j.mri.2014.02.002. Epub 2014 Feb 10.

10.

A 3D-printed high power nuclear spin polarizer.

Nikolaou P, Coffey AM, Walkup LL, Gust BM, LaPierre CD, Koehnemann E, Barlow MJ, Rosen MS, Goodson BM, Chekmenev EY.

J Am Chem Soc. 2014 Jan 29;136(4):1636-42. doi: 10.1021/ja412093d. Epub 2014 Jan 21.

11.

Identification of mureidomycin analogues and functional analysis of an N-acetyltransferase in napsamycin biosynthesis.

Tang X, Gross M, Xie Y, Kulik A, Gust B.

Chembiochem. 2013 Nov 25;14(17):2248-55. doi: 10.1002/cbic.201300287. Epub 2013 Oct 2.

PMID:
24115404
12.

Near-unity nuclear polarization with an open-source 129Xe hyperpolarizer for NMR and MRI.

Nikolaou P, Coffey AM, Walkup LL, Gust BM, Whiting N, Newton H, Barcus S, Muradyan I, Dabaghyan M, Moroz GD, Rosen MS, Patz S, Barlow MJ, Chekmenev EY, Goodson BM.

Proc Natl Acad Sci U S A. 2013 Aug 27;110(35):14150-5. doi: 10.1073/pnas.1306586110. Epub 2013 Aug 14.

13.

A two-step sulfation in antibiotic biosynthesis requires a type III polyketide synthase.

Tang X, Eitel K, Kaysser L, Kulik A, Grond S, Gust B.

Nat Chem Biol. 2013 Oct;9(10):610-5. doi: 10.1038/nchembio.1310. Epub 2013 Aug 4.

PMID:
23912167
14.

Phage p1-derived artificial chromosomes facilitate heterologous expression of the FK506 gene cluster.

Jones AC, Gust B, Kulik A, Heide L, Buttner MJ, Bibb MJ.

PLoS One. 2013 Jul 11;8(7):e69319. doi: 10.1371/journal.pone.0069319. Print 2013.

15.

Five gene products are required for assembly of the central pyrrole moiety of coumermycin A1.

Novotna J, Gust B, Kulik A, Spizek J, Heide L.

J Ind Microbiol Biotechnol. 2013 Aug;40(8):915-25. doi: 10.1007/s10295-013-1266-6. Epub 2013 May 8.

PMID:
23652970
16.

Coiled-coil protein Scy is a key component of a multiprotein assembly controlling polarized growth in Streptomyces.

Holmes NA, Walshaw J, Leggett RM, Thibessard A, Dalton KA, Gillespie MD, Hemmings AM, Gust B, Kelemen GH.

Proc Natl Acad Sci U S A. 2013 Jan 29;110(5):E397-406. doi: 10.1073/pnas.1210657110. Epub 2013 Jan 7.

17.

The biosynthesis of caprazamycins and related liponucleoside antibiotics: new insights.

Gust B, Eitel K, Tang X.

Biol Chem. 2013 Feb;394(2):251-9. doi: 10.1515/hsz-2012-0274. Review.

PMID:
23104838
18.

Genome sequence of the bacterium Streptomyces davawensis JCM 4913 and heterologous production of the unique antibiotic roseoflavin.

Jankowitsch F, Schwarz J, Rückert C, Gust B, Szczepanowski R, Blom J, Pelzer S, Kalinowski J, Mack M.

J Bacteriol. 2012 Dec;194(24):6818-27. doi: 10.1128/JB.01592-12. Epub 2012 Oct 5.

19.

Mutational analysis of a phenazine biosynthetic gene cluster in Streptomyces anulatus 9663.

Saleh O, Flinspach K, Westrich L, Kulik A, Gust B, Fiedler HP, Heide L.

Beilstein J Org Chem. 2012;8:501-13. doi: 10.3762/bjoc.8.57. Epub 2012 Apr 4.

20.

Two pathways for pyrrole formation in coumermycin A(1) biosynthesis: the central pyrrole moiety is formed from L-threonine.

Siebenberg S, Burkard N, Knuplesch A, Gust B, Grond S, Heide L.

Chembiochem. 2011 Nov 25;12(17):2677-85. doi: 10.1002/cbic.201100494. Epub 2011 Sep 27.

PMID:
21953874
21.

The biosynthetic genes for prenylated phenazines are located at two different chromosomal loci of Streptomyces cinnamonensis DSM 1042.

Seeger K, Flinspach K, Haug-Schifferdecker E, Kulik A, Gust B, Fiedler HP, Heide L.

Microb Biotechnol. 2011 Mar;4(2):252-62. doi: 10.1111/j.1751-7915.2010.00234.x. Epub 2010 Dec 8.

22.

The actinobacteria-specific gene wblA controls major developmental transitions in Streptomyces coelicolor A3(2).

Fowler-Goldsworthy K, Gust B, Mouz S, Chandra G, Findlay KC, Chater KF.

Microbiology. 2011 May;157(Pt 5):1312-1328. doi: 10.1099/mic.0.047555-0. Epub 2011 Feb 17.

PMID:
21330440
23.

Identification of a napsamycin biosynthesis gene cluster by genome mining.

Kaysser L, Tang X, Wemakor E, Sedding K, Hennig S, Siebenberg S, Gust B.

Chembiochem. 2011 Feb 11;12(3):477-87. doi: 10.1002/cbic.201000460. Epub 2010 Dec 29.

PMID:
21290549
24.

Identification and structural elucidation of new caprazamycins from Streptomyces sp. MK730-62F2 by liquid chromatography/electrospray ionization tandem mass spectrometry.

Siebenberg S, Kaysser L, Wemakor E, Heide L, Gust B, Kammerer B.

Rapid Commun Mass Spectrom. 2011 Feb 28;25(4):495-502. doi: 10.1002/rcm.4889.

PMID:
21259358
25.

Heterologous expression of the biosynthetic gene clusters of coumermycin A(1), clorobiocin and caprazamycins in genetically modified Streptomyces coelicolor strains.

Flinspach K, Westrich L, Kaysser L, Siebenberg S, Gomez-Escribano JP, Bibb M, Gust B, Heide L.

Biopolymers. 2010 Sep;93(9):823-32. doi: 10.1002/bip.21493.

PMID:
20578003
26.

Formation and attachment of the deoxysugar moiety and assembly of the gene cluster for caprazamycin biosynthesis.

Kaysser L, Wemakor E, Siebenberg S, Salas JA, Sohng JK, Kammerer B, Gust B.

Appl Environ Microbiol. 2010 Jun;76(12):4008-18. doi: 10.1128/AEM.02740-09. Epub 2010 Apr 23.

27.
28.

Reducing the variability of antibiotic production in Streptomyces by cultivation in 24-square deepwell plates.

Siebenberg S, Bapat PM, Lantz AE, Gust B, Heide L.

J Biosci Bioeng. 2010 Mar;109(3):230-4. doi: 10.1016/j.jbiosc.2009.08.479. Epub 2009 Sep 16.

PMID:
20159569
29.

A new arylsulfate sulfotransferase involved in liponucleoside antibiotic biosynthesis in streptomycetes.

Kaysser L, Eitel K, Tanino T, Siebenberg S, Matsuda A, Ichikawa S, Gust B.

J Biol Chem. 2010 Apr 23;285(17):12684-94. doi: 10.1074/jbc.M109.094490. Epub 2010 Feb 15.

30.

Use of an inducible promoter for antibiotic production in a heterologous host.

Dangel V, Westrich L, Smith MC, Heide L, Gust B.

Appl Microbiol Biotechnol. 2010 Jun;87(1):261-9. doi: 10.1007/s00253-009-2435-4. Epub 2010 Feb 2.

PMID:
20127238
31.

Analysis of the liposidomycin gene cluster leads to the identification of new caprazamycin derivatives.

Kaysser L, Siebenberg S, Kammerer B, Gust B.

Chembiochem. 2010 Jan 25;11(2):191-6. doi: 10.1002/cbic.200900637. No abstract available.

PMID:
20039253
32.

Transcriptional regulation of the novobiocin biosynthetic gene cluster.

Dangel V, Härle J, Goerke C, Wolz C, Gust B, Pernodet JL, Heide L.

Microbiology. 2009 Dec;155(Pt 12):4025-4035. doi: 10.1099/mic.0.032649-0. Epub 2009 Sep 17.

PMID:
19762445
33.

Chapter 7. Cloning and analysis of natural product pathways.

Gust B.

Methods Enzymol. 2009;458:159-80. doi: 10.1016/S0076-6879(09)04807-1.

PMID:
19374983
34.

Identification and manipulation of the caprazamycin gene cluster lead to new simplified liponucleoside antibiotics and give insights into the biosynthetic pathway.

Kaysser L, Lutsch L, Siebenberg S, Wemakor E, Kammerer B, Gust B.

J Biol Chem. 2009 May 29;284(22):14987-96. doi: 10.1074/jbc.M901258200. Epub 2009 Apr 7.

35.

Aromatic prenylation in phenazine biosynthesis: dihydrophenazine-1-carboxylate dimethylallyltransferase from Streptomyces anulatus.

Saleh O, Gust B, Boll B, Fiedler HP, Heide L.

J Biol Chem. 2009 May 22;284(21):14439-47. doi: 10.1074/jbc.M901312200. Epub 2009 Apr 1.

36.

Use of a halogenase of hormaomycin biosynthesis for formation of new clorobiocin analogues with 5-chloropyrrole moieties.

Heide L, Westrich L, Anderle C, Gust B, Kammerer B, Piel J.

Chembiochem. 2008 Aug 11;9(12):1992-9. doi: 10.1002/cbic.200800186.

PMID:
18655076
37.

novE and novG act as positive regulators of novobiocin biosynthesis.

Dangel V, Eustáquio AS, Gust B, Heide L.

Arch Microbiol. 2008 Nov;190(5):509-19. doi: 10.1007/s00203-008-0396-0. Epub 2008 Jun 21.

PMID:
18568336
38.
39.

Assembly and heterologous expression of the coumermycin A1 gene cluster and production of new derivatives by genetic engineering.

Wolpert M, Heide L, Kammerer B, Gust B.

Chembiochem. 2008 Mar 3;9(4):603-12. doi: 10.1002/cbic.200700483.

PMID:
18288655
40.
41.

Improved mutasynthetic approaches for the production of modified aminocoumarin antibiotics.

Anderle C, Hennig S, Kammerer B, Li SM, Wessjohann L, Gust B, Heide L.

Chem Biol. 2007 Aug;14(8):955-67.

42.

A soluble, magnesium-independent prenyltransferase catalyzes reverse and regular C-prenylations and O-prenylations of aromatic substrates.

Haagen Y, Unsöld I, Westrich L, Gust B, Richard SB, Noel JP, Heide L.

FEBS Lett. 2007 Jun 26;581(16):2889-93. Epub 2007 May 22.

43.

Effects of deletions of mbtH-like genes on clorobiocin biosynthesis in Streptomyces coelicolor.

Wolpert M, Gust B, Kammerer B, Heide L.

Microbiology. 2007 May;153(Pt 5):1413-1423. doi: 10.1099/mic.0.2006/002998-0.

PMID:
17464055
44.

Biosynthesis of clorobiocin: investigation of the transfer and methylation of the pyrrolyl-2-carboxyl moiety.

Anderle C, Alt S, Gulder T, Bringmann G, Kammerer B, Gust B, Heide L.

Arch Microbiol. 2007 Mar;187(3):227-37. Epub 2006 Nov 25.

PMID:
17308937
45.

A gene cluster for prenylated naphthoquinone and prenylated phenazine biosynthesis in Streptomyces cinnamonensis DSM 1042.

Haagen Y, Glück K, Fay K, Kammerer B, Gust B, Heide L.

Chembiochem. 2006 Dec;7(12):2016-27.

PMID:
17103476
46.
47.

Expression of Cre recombinase during transient phage infection permits efficient marker removal in Streptomyces.

Khodakaramian G, Lissenden S, Gust B, Moir L, Hoskisson PA, Chater KF, Smith MC.

Nucleic Acids Res. 2006 Feb 9;34(3):e20.

48.

Heterologous expression of novobiocin and clorobiocin biosynthetic gene clusters.

Eustáquio AS, Gust B, Galm U, Li SM, Chater KF, Heide L.

Appl Environ Microbiol. 2005 May;71(5):2452-9.

49.

Developmental-stage-specific assembly of ParB complexes in Streptomyces coelicolor hyphae.

Jakimowicz D, Gust B, Zakrzewska-Czerwinska J, Chater KF.

J Bacteriol. 2005 May;187(10):3572-80.

50.

Production of 8'-halogenated and 8'-unsubstituted novobiocin derivatives in genetically engineered streptomyces coelicolor strains.

Eustáquio AS, Gust B, Li SM, Pelzer S, Wohlleben W, Chater KF, Heide L.

Chem Biol. 2004 Nov;11(11):1561-72.

Supplemental Content

Support Center