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Items: 39

1.

Increase in lysophosphatidate acyltransferase activity in oilseed rape (Brassica napus) increases seed triacylglycerol content despite its low intrinsic flux control coefficient.

Woodfield HK, Fenyk S, Wallington E, Bates RE, Brown A, Guschina IA, Marillia EF, Taylor DC, Fell D, Harwood JL, Fawcett T.

New Phytol. 2019 Oct;224(2):700-711. doi: 10.1111/nph.16100. Epub 2019 Sep 14.

2.

Dihomo-γ-linolenic acid inhibits several key cellular processes associated with atherosclerosis.

Gallagher H, Williams JO, Ferekidis N, Ismail A, Chan YH, Michael DR, Guschina IA, Tyrrell VJ, O'Donnell VB, Harwood JL, Khozin-Goldberg I, Boussiba S, Ramji DP.

Biochim Biophys Acta Mol Basis Dis. 2019 Sep 1;1865(9):2538-2550. doi: 10.1016/j.bbadis.2019.06.011. Epub 2019 Jun 13.

3.

Using lipidomics to reveal details of lipid accumulation in developing seeds from oilseed rape (Brassica napus L.).

Woodfield HK, Cazenave-Gassiot A, Haslam RP, Guschina IA, Wenk MR, Harwood JL.

Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Mar;1863(3):339-348. doi: 10.1016/j.bbalip.2017.12.010. Epub 2017 Dec 22.

4.

Unacylated ghrelin promotes adipogenesis in rodent bone marrow via ghrelin O-acyl transferase and GHS-R1a activity: evidence for target cell-induced acylation.

Hopkins AL, Nelson TA, Guschina IA, Parsons LC, Lewis CL, Brown RC, Christian HC, Davies JS, Wells T.

Sci Rep. 2017 Mar 31;7:45541. doi: 10.1038/srep45541.

5.

Spatial and Temporal Mapping of Key Lipid Species in Brassica napus Seeds.

Woodfield HK, Sturtevant D, Borisjuk L, Munz E, Guschina IA, Chapman K, Harwood JL.

Plant Physiol. 2017 Apr;173(4):1998-2009. doi: 10.1104/pp.16.01705. Epub 2017 Feb 10.

6.

Paradoxical leanness in the imprinting-centre deletion mouse model for Prader-Willi syndrome.

Golding DM, Rees DJ, Davies JR, Relkovic D, Furby HV, Guschina IA, Hopkins AL, Davies JS, Resnick JL, Isles AR, Wells T.

J Endocrinol. 2017 Jan;232(1):123-135. Epub 2016 Oct 31.

7.

Light-Induced Changes in Fatty Acid Profiles of Specific Lipid Classes in Several Freshwater Phytoplankton Species.

Wacker A, Piepho M, Harwood JL, Guschina IA, Arts MT.

Front Plant Sci. 2016 Mar 16;7:264. doi: 10.3389/fpls.2016.00264. eCollection 2016.

8.

Dietary DHA supplementation causes selective changes in phospholipids from different brain regions in both wild type mice and the Tg2576 mouse model of Alzheimer's disease.

Bascoul-Colombo C, Guschina IA, Maskrey BH, Good M, O'Donnell VB, Harwood JL.

Biochim Biophys Acta. 2016 Jun;1861(6):524-37. doi: 10.1016/j.bbalip.2016.03.005. Epub 2016 Mar 9.

9.

Characterisation of adipocyte-derived extracellular vesicles released pre- and post-adipogenesis.

Connolly KD, Guschina IA, Yeung V, Clayton A, Draman MS, Von Ruhland C, Ludgate M, James PE, Rees DA.

J Extracell Vesicles. 2015 Nov 24;4:29159. doi: 10.3402/jev.v4.29159. eCollection 2015.

10.

Young women with polycystic ovary syndrome have raised levels of circulating annexin V-positive platelet microparticles.

Willis GR, Connolly K, Ladell K, Davies TS, Guschina IA, Ramji D, Miners K, Price DA, Clayton A, James PE, Rees DA.

Hum Reprod. 2014 Dec;29(12):2756-63. doi: 10.1093/humrep/deu281. Epub 2014 Oct 21.

PMID:
25336711
11.

Lipoprotein-apheresis reduces circulating microparticles in individuals with familial hypercholesterolemia.

Connolly KD, Willis GR, Datta DB, Ellins EA, Ladell K, Price DA, Guschina IA, Rees DA, James PE.

J Lipid Res. 2014 Oct;55(10):2064-72. doi: 10.1194/jlr.M049726. Epub 2014 Aug 13.

12.

Studies on the regulation of lipid biosynthesis in plants: application of control analysis to soybean.

Guschina IA, Everard JD, Kinney AJ, Quant PA, Harwood JL.

Biochim Biophys Acta. 2014 Jun;1838(6):1488-500. doi: 10.1016/j.bbamem.2014.02.008. Epub 2014 Feb 22. Review. Erratum in: Biochim Biophys Acta. 2015 Jan;1848(1 Pt A):104.

13.

Endemic infection reduces transmission potential of an epidemic parasite during co-infection.

Randall J, Cable J, Guschina IA, Harwood JL, Lello J.

Proc Biol Sci. 2013 Aug 21;280(1769):20131500. doi: 10.1098/rspb.2013.1500. Print 2013 Oct 22.

14.

Regulation of lipid synthesis in oil crops.

Harwood JL, Guschina IA.

FEBS Lett. 2013 Jun 27;587(13):2079-81. doi: 10.1016/j.febslet.2013.05.018. Epub 2013 May 16. Review.

15.

Increased lipolysis and altered lipid homeostasis protect γ-synuclein-null mutant mice from diet-induced obesity.

Millership S, Ninkina N, Guschina IA, Norton J, Brambilla R, Oort PJ, Adams SH, Dennis RJ, Voshol PJ, Rochford JJ, Buchman VL.

Proc Natl Acad Sci U S A. 2012 Dec 18;109(51):20943-8. doi: 10.1073/pnas.1210022110. Epub 2012 Dec 3. Erratum in: Proc Natl Acad Sci U S A. 2013 Mar 26;110(13):5269. Brambilla, Ricardo [corrected to Brambilla, Riccardo].

16.

Metabolic control analysis of developing oilseed rape (Brassica napus cv Westar) embryos shows that lipid assembly exerts significant control over oil accumulation.

Tang M, Guschina IA, O'Hara P, Slabas AR, Quant PA, Fawcett T, Harwood JL.

New Phytol. 2012 Oct;196(2):414-426. doi: 10.1111/j.1469-8137.2012.04262.x. Epub 2012 Aug 20.

17.

Opa3, a novel regulator of mitochondrial function, controls thermogenesis and abdominal fat mass in a mouse model for Costeff syndrome.

Wells T, Davies JR, Guschina IA, Ball DJ, Davies JS, Davies VJ, Evans BA, Votruba M.

Hum Mol Genet. 2012 Nov 15;21(22):4836-44. doi: 10.1093/hmg/dds315. Epub 2012 Aug 6.

PMID:
22869679
18.

Conserved valproic-acid-induced lipid droplet formation in Dictyostelium and human hepatocytes identifies structurally active compounds.

Elphick LM, Pawolleck N, Guschina IA, Chaieb L, Eikel D, Nau H, Harwood JL, Plant NJ, Williams RS.

Dis Model Mech. 2012 Mar;5(2):231-40. doi: 10.1242/dmm.008391. Epub 2011 Oct 14.

19.

Eicosapentaenoic acid and docosahexaenoic acid regulate modified LDL uptake and macropinocytosis in human macrophages.

McLaren JE, Michael DR, Guschina IA, Harwood JL, Ramji DP.

Lipids. 2011 Nov;46(11):1053-61. doi: 10.1007/s11745-011-3598-1. Epub 2011 Aug 7.

PMID:
21822944
20.

CD55 deficiency protects against atherosclerosis in ApoE-deficient mice via C3a modulation of lipid metabolism.

Lewis RD, Perry MJ, Guschina IA, Jackson CL, Morgan BP, Hughes TR.

Am J Pathol. 2011 Oct;179(4):1601-7. doi: 10.1016/j.ajpath.2011.06.015. Epub 2011 Aug 2.

21.

RISING WATER TEMPERATURES ALTER LIPID DYNAMICS AND REDUCE N-3 ESSENTIAL FATTY ACID CONCENTRATIONS IN SCENEDESMUS OBLIQUUS (CHLOROPHYTA)(1).

Fuschino JR, Guschina IA, Dobson G, Yan ND, Harwood JL, Arts MT.

J Phycol. 2011 Aug;47(4):763-74. doi: 10.1111/j.1529-8817.2011.01024.x.

PMID:
27020012
22.

The action of herbicides on fatty acid biosynthesis and elongation in barley and cucumber.

Yang X, Guschina IA, Hurst S, Wood S, Langford M, Hawkes T, Harwood JL.

Pest Manag Sci. 2010 Jul;66(7):794-800. doi: 10.1002/ps.1944.

PMID:
20533380
23.

The microaerophilic flagellate, Trichomonas vaginalis, contains unusual acyl lipids but no detectable cardiolipin.

Guschina IA, Harris KM, Maskrey B, Goldberg B, Lloyd D, Harwood JL.

J Eukaryot Microbiol. 2009 Jan-Feb;56(1):52-7. doi: 10.1111/j.1550-7408.2008.00365.x.

PMID:
19335774
24.

Ghrelin induces abdominal obesity via GHS-R-dependent lipid retention.

Davies JS, Kotokorpi P, Eccles SR, Barnes SK, Tokarczuk PF, Allen SK, Whitworth HS, Guschina IA, Evans BA, Mode A, Zigman JM, Wells T.

Mol Endocrinol. 2009 Jun;23(6):914-24. doi: 10.1210/me.2008-0432. Epub 2009 Mar 19.

25.

The versatility of algae and their lipid metabolism.

Harwood JL, Guschina IA.

Biochimie. 2009 Jun;91(6):679-84. doi: 10.1016/j.biochi.2008.11.004. Epub 2008 Nov 27. Review.

PMID:
19063932
26.

The utilization and desaturation of oleate and linoleate during glycerolipid biosynthesis in olive (Olea europaea L.) callus cultures.

Hernández ML, Guschina IA, Martínez-Rivas JM, Mancha M, Harwood JL.

J Exp Bot. 2008;59(9):2425-35. doi: 10.1093/jxb/ern121. Epub 2008 May 31.

27.

Endocrine disrupting chemicals accumulate in earthworms exposed to sewage effluent.

Markman S, Guschina IA, Barnsley S, Buchanan KL, Pascoe D, Müller CT.

Chemosphere. 2007 Nov;70(1):119-25. Epub 2007 Aug 1.

PMID:
17675209
28.

A randomised cross-over trial in healthy adults indicating improved absorption of omega-3 fatty acids by pre-emulsification.

Garaiova I, Guschina IA, Plummer SF, Tang J, Wang D, Plummer NT.

Nutr J. 2007 Jan 25;6:4.

29.

Mechanisms of temperature adaptation in poikilotherms.

Guschina IA, Harwood JL.

FEBS Lett. 2006 Oct 9;580(23):5477-83. Epub 2006 Jun 30. Review.

30.

Lead and copper effects on lipid metabolism in cultured lichen photobionts with different phosphorus status.

Guschina IA, Harwood JL.

Phytochemistry. 2006 Aug;67(16):1731-9. Epub 2006 Mar 9.

PMID:
16524604
31.

Lipids and lipid metabolism in eukaryotic algae.

Guschina IA, Harwood JL.

Prog Lipid Res. 2006 Mar;45(2):160-86. Epub 2006 Feb 6. Review.

PMID:
16492482
32.

Daphnia magna can tolerate short-term starvation without major changes in lipid metabolism.

Bychek EA, Dobson GA, Harwood JL, Guschina IA.

Lipids. 2005 Jun;40(6):599-608.

PMID:
16149739
33.

Lipid metabolism in cultured lichen photobionts with different phosphorus status.

Guschina IA, Dobson G, Harwood JL.

Phytochemistry. 2003 Sep;64(1):209-17.

PMID:
12946419
34.
35.

Macrolactone glycosides of three lichen acids from Acarospora gobiensis, a lichen of Central Asia.

Rezanka T, Guschina IA.

Phytochemistry. 2001 Dec;58(8):1281-7.

PMID:
11738423
36.

Glycoside esters from lichens of central Asia.

Rezanka T, Guschina IA.

Phytochemistry. 2001 Oct;58(3):509-16.

PMID:
11557085
37.

Further glucosides of lichens' acids from Central Asian lichens.

Rezanka T, Guschina IA.

Phytochemistry. 2001 Jan;56(2):181-8.

PMID:
11219812
38.

Effect of copper and lead on lipid metabolism in bryophytes and lichens.

Guschina IA, Harwood JL.

Biochem Soc Trans. 2000 Dec;28(6):910-2.

PMID:
11171254
39.

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