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Items: 21

1.

Bile acid-induced "Minority MOMP" promotes esophageal carcinogenesis while maintaining apoptotic resistance via Mcl-1.

Xu Y, Surman DR, Diggs L, Xi S, Gao S, Gurusamy D, McLoughlin K, Drake J, Feingold P, Brown K, Wangsa D, Wangsa D, Zhang X, Ried T, Davis JL, Hernandez J, Hoang C, Souza RF, Schrump DS, Taylor Ripley R.

Oncogene. 2019 Sep 30. doi: 10.1038/s41388-019-1029-6. [Epub ahead of print]

PMID:
31570787
2.

Lipocalin-2 (Lcn-2) Attenuates Polymicrobial Sepsis with LPS Preconditioning (LPS Tolerance) in FcGRIIb Deficient Lupus Mice.

Ondee T, Gillen J, Visitchanakun P, Somparn P, Issara-Amphorn J, Dang Phi C, Chancharoenthana W, Gurusamy D, Nita-Lazar A, Leelahavanichkul A.

Cells. 2019 Sep 11;8(9). pii: E1064. doi: 10.3390/cells8091064.

3.

Host conditioning with IL-1β improves the antitumor function of adoptively transferred T cells.

Lee PH, Yamamoto TN, Gurusamy D, Sukumar M, Yu Z, Hu-Li J, Kawabe T, Gangaplara A, Kishton RJ, Henning AN, Vodnala SK, Germain RN, Paul WE, Restifo NP.

J Exp Med. 2019 Aug 12. pii: jem.20181218. doi: 10.1084/jem.20181218. [Epub ahead of print]

PMID:
31405895
4.

Development of CS-TPP-dsRNA nanoparticles to enhance RNAi efficiency in the yellow fever mosquito, Aedes aegypti.

Dhandapani RK, Gurusamy D, Howell JL, Palli SR.

Sci Rep. 2019 Jun 19;9(1):8775. doi: 10.1038/s41598-019-45019-z.

5.

The transcription factor c-Myb regulates CD8+ T cell stemness and antitumor immunity.

Gautam S, Fioravanti J, Zhu W, Le Gall JB, Brohawn P, Lacey NE, Hu J, Hocker JD, Hawk NV, Kapoor V, Telford WG, Gurusamy D, Yu Z, Bhandoola A, Xue HH, Roychoudhuri R, Higgs BW, Restifo NP, Bender TP, Ji Y, Gattinoni L.

Nat Immunol. 2019 Mar;20(3):337-349. doi: 10.1038/s41590-018-0311-z. Epub 2019 Feb 18.

6.

T cells genetically engineered to overcome death signaling enhance adoptive cancer immunotherapy.

Yamamoto TN, Lee PH, Vodnala SK, Gurusamy D, Kishton RJ, Yu Z, Eidizadeh A, Eil R, Fioravanti J, Gattinoni L, Kochenderfer JN, Fry TJ, Aksoy BA, Hammerbacher JE, Cruz AC, Siegel RM, Restifo NP, Klebanoff CA.

J Clin Invest. 2019 Feb 25;129(4):1551-1565. doi: 10.1172/JCI121491. eCollection 2019 Feb 25.

7.

Double-stranded RNA binding protein, Staufen, is required for the initiation of RNAi in coleopteran insects.

Yoon JS, Mogilicherla K, Gurusamy D, Chen X, Chereddy SCRR, Palli SR.

Proc Natl Acad Sci U S A. 2018 Aug 14;115(33):8334-8339. doi: 10.1073/pnas.1809381115. Epub 2018 Jul 30.

8.

Generation of Tumor Antigen-Specific iPSC-Derived Thymic Emigrants Using a 3D Thymic Culture System.

Vizcardo R, Klemen ND, Islam SMR, Gurusamy D, Tamaoki N, Yamada D, Koseki H, Kidder BL, Yu Z, Jia L, Henning AN, Good ML, Bosch-Marce M, Maeda T, Liu C, Abdullaev Z, Pack S, Palmer DC, Stroncek DF, Ito F, Flomerfelt FA, Kruhlak MJ, Restifo NP.

Cell Rep. 2018 Mar 20;22(12):3175-3190. doi: 10.1016/j.celrep.2018.02.087.

9.

Inhibition of AKT signaling uncouples T cell differentiation from expansion for receptor-engineered adoptive immunotherapy.

Klebanoff CA, Crompton JG, Leonardi AJ, Yamamoto TN, Chandran SS, Eil RL, Sukumar M, Vodnala SK, Hu J, Ji Y, Clever D, Black MA, Gurusamy D, Kruhlak MJ, Jin P, Stroncek DF, Gattinoni L, Feldman SA, Restifo NP.

JCI Insight. 2017 Dec 7;2(23). pii: 95103. doi: 10.1172/jci.insight.95103.

10.

Accumulation of dsRNA in endosomes contributes to inefficient RNA interference in the fall armyworm, Spodoptera frugiperda.

Yoon JS, Gurusamy D, Palli SR.

Insect Biochem Mol Biol. 2017 Nov;90:53-60. doi: 10.1016/j.ibmb.2017.09.011. Epub 2017 Sep 23.

PMID:
28951282
11.

Novel "Elements" of Immune Suppression within the Tumor Microenvironment.

Gurusamy D, Clever D, Eil R, Restifo NP.

Cancer Immunol Res. 2017 Jun;5(6):426-433. doi: 10.1158/2326-6066.CIR-17-0117. Review.

12.

Genome-wide transcriptomic and proteomic analyses of bollworm-infested developing cotton bolls revealed the genes and pathways involved in the insect pest defence mechanism.

Kumar S, Kanakachari M, Gurusamy D, Kumar K, Narayanasamy P, Kethireddy Venkata P, Solanke A, Gamanagatti S, Hiremath V, Katageri IS, Leelavathi S, Kumar PA, Reddy VS.

Plant Biotechnol J. 2016 Jun;14(6):1438-55. doi: 10.1111/pbi.12508. Epub 2016 Jan 22.

13.

CD4+ T Cell Help Selectively Enhances High-Avidity Tumor Antigen-Specific CD8+ T Cells.

Zhu Z, Cuss SM, Singh V, Gurusamy D, Shoe JL, Leighty R, Bronte V, Hurwitz AA.

J Immunol. 2015 Oct 1;195(7):3482-9. doi: 10.4049/jimmunol.1401571. Epub 2015 Aug 28.

14.

Hepatocyte growth factor-like protein is a positive regulator of early mammary gland ductal morphogenesis.

Gurusamy D, Ruiz-Torres SJ, Johnson AL, Smith DA, Waltz SE.

Mech Dev. 2014 Aug;133:11-22. doi: 10.1016/j.mod.2014.07.002. Epub 2014 Jul 15.

15.

Ron receptor signaling is protective against DSS-induced colitis in mice.

Kulkarni RM, Stuart WD, Gurusamy D, Waltz SE.

Am J Physiol Gastrointest Liver Physiol. 2014 Jun 15;306(12):G1065-74. doi: 10.1152/ajpgi.00421.2013. Epub 2014 Apr 17.

16.

Myeloid-specific expression of Ron receptor kinase promotes prostate tumor growth.

Gurusamy D, Gray JK, Pathrose P, Kulkarni RM, Finkleman FD, Waltz SE.

Cancer Res. 2013 Mar 15;73(6):1752-63. doi: 10.1158/0008-5472.CAN-12-2474. Epub 2013 Jan 17.

17.

Estrogen receptor alpha deletion enhances the metastatic phenotype of Ron overexpressing mammary tumors in mice.

Marshall AM, McClaine RJ, Gurusamy D, Gray JK, Lewnard KE, Khan SA, Waltz SE.

Mol Cancer. 2012 Jan 6;11:2. doi: 10.1186/1476-4598-11-2.

18.

The Ron receptor promotes prostate tumor growth in the TRAMP mouse model.

Thobe MN, Gray JK, Gurusamy D, Paluch AM, Wagh PK, Pathrose P, Lentsch AB, Waltz SE.

Oncogene. 2011 Dec 15;30(50):4990-8. doi: 10.1038/onc.2011.205. Epub 2011 May 30.

19.

The Ron receptor tyrosine kinase positively regulates angiogenic chemokine production in prostate cancer cells.

Thobe MN, Gurusamy D, Pathrose P, Waltz SE.

Oncogene. 2010 Jan 14;29(2):214-26. doi: 10.1038/onc.2009.331. Epub 2009 Oct 19.

20.

Ron receptor tyrosine kinase negatively regulates TNFalpha production in alveolar macrophages by inhibiting NF-kappaB activity and Adam17 production.

Nikolaidis NM, Gray JK, Gurusamy D, Fox W, Stuart WD, Huber N, Waltz SE.

Shock. 2010 Feb;33(2):197-204. doi: 10.1097/SHK.0b013e3181ae8155.

21.

Dengue fever outbreaks in two villages of Dharmapuri district in Tamil Nadu.

Victor TJ, Malathi M, Gurusamy D, Desai A, Ravi V, Narayanasamy G, Anuradha L, Rani C, Krishnamurthy P.

Indian J Med Res. 2002 Oct;116:133-9.

PMID:
12674826

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