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Anisotropic Platinum Nanoparticle-Induced Cytotoxicity, Apoptosis, Inflammatory Response, and Transcriptomic and Molecular Pathways in Human Acute Monocytic Leukemia Cells.

Gurunathan S, Jeyaraj M, La H, Yoo H, Choi Y, Do JT, Park C, Kim JH, Hong K.

Int J Mol Sci. 2020 Jan 9;21(2). pii: E440. doi: 10.3390/ijms21020440.


Immunogenicity and safety of a multi-dose quadrivalent inactivated influenza vaccine in individuals aged 6 months to 17 years: a randomized phase III trial.

Ojeda J, Arredondo JL, Salcedo P, Paredes-Paredes M, Dupuy M, Petit C, Chabanon AL, Rivas E, Gurunathan S, De Bruijn I, Pepin S.

Hum Vaccin Immunother. 2019 Dec 20:1-5. doi: 10.1080/21645515.2019.1697595. [Epub ahead of print]


A Comprehensive Review on the Synthesis, Characterization, and Biomedical Application of Platinum Nanoparticles.

Jeyaraj M, Gurunathan S, Qasim M, Kang MH, Kim JH.

Nanomaterials (Basel). 2019 Dec 2;9(12). pii: E1719. doi: 10.3390/nano9121719. Review.


Single Nucleotide Polymorphisms in Starch Biosynthetic Genes Associated With Increased Resistant Starch Concentration in Rice Mutant.

Gurunathan S, Ramadoss BR, Mudili V, Siddaiah C, Kalagatur NK, Bapu JRK, Mohan CD, Alqarawi AA, Hashem A, Abd Allah EF.

Front Genet. 2019 Nov 15;10:946. doi: 10.3389/fgene.2019.00946. eCollection 2019.


Hybrid clinical trials to generate real-world evidence: design considerations from a sponsor's perspective.

Zhu M, Sridhar S, Hollingsworth R, Chit A, Kimball T, Murmello K, Greenberg M, Gurunathan S, Chen J.

Contemp Clin Trials. 2019 Oct 24:105856. doi: 10.1016/j.cct.2019.105856. [Epub ahead of print]


Mitochondrial Peptide Humanin Protects Silver Nanoparticles-Induced Neurotoxicity in Human Neuroblastoma Cancer Cells (SH-SY5Y).

Gurunathan S, Jeyaraj M, Kang MH, Kim JH.

Int J Mol Sci. 2019 Sep 9;20(18). pii: E4439. doi: 10.3390/ijms20184439.


Tangeretin-Assisted Platinum Nanoparticles Enhance the Apoptotic Properties of Doxorubicin: Combination Therapy for Osteosarcoma Treatment.

Gurunathan S, Jeyaraj M, Kang MH, Kim JH.

Nanomaterials (Basel). 2019 Jul 29;9(8). pii: E1089. doi: 10.3390/nano9081089.


Reply to 'Management of noncompaction requires optimisation'.

Gurunathan S, Senior R.

Echo Res Pract. 2019 May 31;6(3):L3-L4. doi: 10.1530/ERP-19-0037. eCollection 2019 Sep. No abstract available.


Evaluation of Graphene Oxide Induced Cellular Toxicity and Transcriptome Analysis in Human Embryonic Kidney Cells.

Gurunathan S, Arsalan Iqbal M, Qasim M, Park CH, Yoo H, Hwang JH, Uhm SJ, Song H, Park C, Do JT, Choi Y, Kim JH, Hong K.

Nanomaterials (Basel). 2019 Jul 2;9(7). pii: E969. doi: 10.3390/nano9070969.


Cytotoxicity and Transcriptomic Analyses of Biogenic Palladium Nanoparticles in Human Ovarian Cancer Cells (SKOV3).

Gurunathan S, Qasim M, Park CH, Arsalan Iqbal M, Yoo H, Hwang JH, Uhm SJ, Song H, Park C, Choi Y, Kim JH, Hong K.

Nanomaterials (Basel). 2019 May 22;9(5). pii: E787. doi: 10.3390/nano9050787.


The Effects of Apigenin-Biosynthesized Ultra-Small Platinum Nanoparticles on the Human Monocytic THP-1 Cell Line.

Gurunathan S, Jeyaraj M, Kang MH, Kim JH.

Cells. 2019 May 10;8(5). pii: E444. doi: 10.3390/cells8050444.


Graphene Oxide⁻Platinum Nanoparticle Nanocomposites: A Suitable Biocompatible Therapeutic Agent for Prostate Cancer.

Gurunathan S, Jeyaraj M, Kang MH, Kim JH.

Polymers (Basel). 2019 Apr 23;11(4). pii: E733. doi: 10.3390/polym11040733.


Review of the Isolation, Characterization, Biological Function, and Multifarious Therapeutic Approaches of Exosomes.

Gurunathan S, Kang MH, Jeyaraj M, Qasim M, Kim JH.

Cells. 2019 Apr 3;8(4). pii: E307. doi: 10.3390/cells8040307. Review.


Serine proteases as luminal mediators of intestinal barrier dysfunction and symptom severity in IBS.

Edogawa S, Edwinson AL, Peters SA, Chikkamenahalli LL, Sundt W, Graves S, Gurunathan SV, Breen-Lyles M, Johnson S, Dyer R, Graham R, Chen J, Kashyap P, Farrugia G, Grover M.

Gut. 2020 Jan;69(1):62-73. doi: 10.1136/gutjnl-2018-317416. Epub 2019 Mar 28.


Differential Cytotoxicity of Different Sizes of Graphene Oxide Nanoparticles in Leydig (TM3) and Sertoli (TM4) Cells.

Gurunathan S, Kang MH, Jeyaraj M, Kim JH.

Nanomaterials (Basel). 2019 Jan 22;9(2). pii: E139. doi: 10.3390/nano9020139.


Efficacy, immunogenicity, and safety of a quadrivalent inactivated influenza vaccine in children aged 6-35 months: A multi-season randomised placebo-controlled trial in the Northern and Southern Hemispheres.

Pepin S, Dupuy M, Borja-Tabora CFC, Montellano M, Bravo L, Santos J, de Castro JA, Rivera-Medina DM, Cutland C, Ariza M, Diez-Domingo J, Gonzalez CD, Martinón-Torres F, Papadopoulou-Alataki E, Theodoriadou M, Kazek-Duret MP, Gurunathan S, De Bruijn I; GQM05 Study Group.

Vaccine. 2019 Mar 22;37(13):1876-1884. doi: 10.1016/j.vaccine.2018.11.074. Epub 2018 Dec 14.


Cytotoxicity and Transcriptomic Analysis of Silver Nanoparticles in Mouse Embryonic Fibroblast Cells.

Gurunathan S, Qasim M, Park C, Yoo H, Choi DY, Song H, Park C, Kim JH, Hong K.

Int J Mol Sci. 2018 Nov 16;19(11). pii: E3618. doi: 10.3390/ijms19113618.


Nanoparticle-Mediated Combination Therapy: Two-in-One Approach for Cancer.

Gurunathan S, Kang MH, Qasim M, Kim JH.

Int J Mol Sci. 2018 Oct 20;19(10). pii: E3264. doi: 10.3390/ijms19103264. Review.


Catastrophic stroke in a patient with left ventricular non-compaction.

Gurunathan S, Senior R.

Echo Res Pract. 2018 Sep;5(3):K59-K62. doi: 10.1530/ERP-18-0015.


Combination Effect of Silver Nanoparticles and Histone Deacetylases Inhibitor in Human Alveolar Basal Epithelial Cells.

Gurunathan S, Kang MH, Kim JH.

Molecules. 2018 Aug 15;23(8). pii: E2046. doi: 10.3390/molecules23082046.


Cytotoxic Potential and Molecular Pathway Analysis of Silver Nanoparticles in Human Colon Cancer Cells HCT116.

Gurunathan S, Qasim M, Park C, Yoo H, Kim JH, Hong K.

Int J Mol Sci. 2018 Aug 2;19(8). pii: E2269. doi: 10.3390/ijms19082269.


Prevention of M. tuberculosis Infection with H4:IC31 Vaccine or BCG Revaccination.

Nemes E, Geldenhuys H, Rozot V, Rutkowski KT, Ratangee F, Bilek N, Mabwe S, Makhethe L, Erasmus M, Toefy A, Mulenga H, Hanekom WA, Self SG, Bekker LG, Ryall R, Gurunathan S, DiazGranados CA, Andersen P, Kromann I, Evans T, Ellis RD, Landry B, Hokey DA, Hopkins R, Ginsberg AM, Scriba TJ, Hatherill M; C-040-404 Study Team.

N Engl J Med. 2018 Jul 12;379(2):138-149. doi: 10.1056/NEJMoa1714021.


Effect of Dengue Serostatus on Dengue Vaccine Safety and Efficacy.

Sridhar S, Luedtke A, Langevin E, Zhu M, Bonaparte M, Machabert T, Savarino S, Zambrano B, Moureau A, Khromava A, Moodie Z, Westling T, Mascareñas C, Frago C, Cortés M, Chansinghakul D, Noriega F, Bouckenooghe A, Chen J, Ng SP, Gilbert PB, Gurunathan S, DiazGranados CA.

N Engl J Med. 2018 Jul 26;379(4):327-340. doi: 10.1056/NEJMoa1800820. Epub 2018 Jun 13.


Sex differences in NSAID-induced perturbation of human intestinal barrier function and microbiota.

Edogawa S, Peters SA, Jenkins GD, Gurunathan SV, Sundt WJ, Johnson S, Lennon RJ, Dyer RB, Camilleri M, Kashyap PC, Farrugia G, Chen J, Singh RJ, Grover M.

FASEB J. 2018 Jun 13:fj201800560R. doi: 10.1096/fj.201800560R. [Epub ahead of print]


Biocompatible Gold Nanoparticles Ameliorate Retinoic Acid-Induced Cell Death and Induce Differentiation in F9 Teratocarcinoma Stem Cells.

Gurunathan S, Kim JH.

Nanomaterials (Basel). 2018 Jun 1;8(6). pii: E396. doi: 10.3390/nano8060396.


Long-Term Association of Dipyridamole Stress Myocardial Contrast Echocardiography versus Single-Photon Emission Computed Tomography with Clinical Outcomes in Patients with Known or Suspected Coronary Artery Disease.

Karogiannis N, Vamvakidou A, Gurunathan S, Pabla J, Young G, Senior R.

J Am Soc Echocardiogr. 2018 Aug;31(8):860-869. doi: 10.1016/j.echo.2018.04.001. Epub 2018 May 31.


Antibacterial Efficacy of Silver Nanoparticles on Endometritis Caused by Prevotella melaninogenica and Arcanobacterum pyogenes in Dairy Cattle.

Gurunathan S, Choi YJ, Kim JH.

Int J Mol Sci. 2018 Apr 16;19(4). pii: E1210. doi: 10.3390/ijms19041210.


Cost-effectiveness of a management strategy based on exercise echocardiography versus exercise electrocardiography in patients presenting with suspected angina during long term follow up: A randomized study.

Gurunathan S, Zacharias K, Akhtar M, Ahmed A, Mehta V, Karogiannis N, Vamvakidou A, Khattar R, Senior R.

Int J Cardiol. 2018 May 15;259:1-7. doi: 10.1016/j.ijcard.2018.01.112.


Diagnostic Concordance and Clinical Outcomes in Patients Undergoing Fractional Flow Reserve and Stress Echocardiography for the Assessment of Coronary Stenosis of Intermediate Severity.

Gurunathan S, Ahmed A, Vamvakidou A, Ramzy IS, Akhtar M, Ali A, Karogiannis N, Zidros S, Balaji G, Young G, Elghamaz A, Senior R.

J Am Soc Echocardiogr. 2018 Feb;31(2):180-186. doi: 10.1016/j.echo.2017.10.012. Epub 2017 Dec 13.


The cytotoxic effects of dimethyl sulfoxide in mouse preimplantation embryos: a mechanistic study.

Kang MH, Das J, Gurunathan S, Park HW, Song H, Park C, Kim JH.

Theranostics. 2017 Oct 17;7(19):4735-4752. doi: 10.7150/thno.21662. eCollection 2017.


Graphene Oxide-Silver Nanoparticles Nanocomposite Stimulates Differentiation in Human Neuroblastoma Cancer Cells (SH-SY5Y).

Gurunathan S, Kim JH.

Int J Mol Sci. 2017 Nov 28;18(12). pii: E2549. doi: 10.3390/ijms18122549.


Novel biomolecule lycopene-reduced graphene oxide-silver nanoparticle enhances apoptotic potential of trichostatin A in human ovarian cancer cells (SKOV3).

Zhang XF, Huang FH, Zhang GL, Bai DP, Massimo DF, Huang YF, Gurunathan S.

Int J Nanomedicine. 2017 Oct 13;12:7551-7575. doi: 10.2147/IJN.S144161. eCollection 2017.


Dual functions of silver nanoparticles in F9 teratocarcinoma stem cells, a suitable model for evaluating cytotoxicity- and differentiation-mediated cancer therapy.

Han JW, Gurunathan S, Choi YJ, Kim JH.

Int J Nanomedicine. 2017 Oct 12;12:7529-7549. doi: 10.2147/IJN.S145147. eCollection 2017.


Stress Echocardiography in Stable Coronary Artery Disease.

Gurunathan S, Senior R.

Curr Cardiol Rep. 2017 Oct 18;19(12):121. doi: 10.1007/s11886-017-0935-x. Review.


A rare case of simultaneous pneumoperitoneum and pneumomediastinum with a review of the literature.

Kourounis G, Lim QX, Rashid T, Gurunathan S.

Ann R Coll Surg Engl. 2017 Nov;99(8):e241-e243. doi: 10.1308/rcsann.2017.0165. Epub 2017 Sep 15. Review.


Combination of graphene oxide-silver nanoparticle nanocomposites and cisplatin enhances apoptosis and autophagy in human cervical cancer cells.

Yuan YG, Gurunathan S.

Int J Nanomedicine. 2017 Sep 5;12:6537-6558. doi: 10.2147/IJN.S125281. eCollection 2017.


Zinc oxide nanoparticles induce apoptosis and autophagy in human ovarian cancer cells.

Bai DP, Zhang XF, Zhang GL, Huang YF, Gurunathan S.

Int J Nanomedicine. 2017 Sep 5;12:6521-6535. doi: 10.2147/IJN.S140071. eCollection 2017.


Combination of palladium nanoparticles and tubastatin-A potentiates apoptosis in human breast cancer cells: a novel therapeutic approach for cancer.

Yuan YG, Peng QL, Gurunathan S.

Int J Nanomedicine. 2017 Sep 5;12:6503-6520. doi: 10.2147/IJN.S136142. eCollection 2017.


Silver nanoparticles enhance the apoptotic potential of gemcitabine in human ovarian cancer cells: combination therapy for effective cancer treatment.

Yuan YG, Peng QL, Gurunathan S.

Int J Nanomedicine. 2017 Sep 5;12:6487-6502. doi: 10.2147/IJN.S135482. eCollection 2017.


Quercetin-mediated synthesis of graphene oxide-silver nanoparticle nanocomposites: a suitable alternative nanotherapy for neuroblastoma.

Yuan YG, Wang YH, Xing HH, Gurunathan S.

Int J Nanomedicine. 2017 Aug 16;12:5819-5839. doi: 10.2147/IJN.S140605. eCollection 2017.


Report from the Annual Conference of the British Society of Echocardiography, November 2016, Queen Elizabeth II Conference Centre, London.

Steeds RP, Cowie MR, Rana BS, Chambers JB, Ray S, Srinivasan J, Schwarz K, Neil CJ, Scally C, Horowitz JD, Frenneaux MP, Pislaru C, Dawson DK, Rothwell OJ, George K, Somauroo JD, Lord R, Stembridge M, Shave R, Hoffman M, Ashley EA, Haddad F, Eijsvogels TMH, Oxborough D, Hampson R, Kinsey CD, Gurunathan S, Vamvakidou A, Karogiannis N, Senior R, Ahmadvazir S, Shah BN, Zacharias K, Bowen D, Robinson S, Ihekwaba U, Parker K, Boyd J, Densem CG, Atkinson C, Hinton J, Gaisie EB, Rakhit DJ, Yue AM, Roberts PR, Thomas D, Phen P, Sibley J, Fergey S, Russhard P.

Echo Res Pract. 2017 Sep 1;4(3):M1. doi: 10.1530/ERP-17-0046. No abstract available.


Elicitation of resistance and associated defense responses in Trichoderma hamatum induced protection against pearl millet downy mildew pathogen.

Siddaiah CN, Satyanarayana NR, Mudili V, Kumar Gupta V, Gurunathan S, Rangappa S, Huntrike SS, Srivastava RK.

Sci Rep. 2017 Mar 21;7:43991. doi: 10.1038/srep43991.


Prognostic usefulness of contemporary stress echocardiography in patients with left bundle branch block and impact of contrast use in improving prediction of outcome.

Vamvakidou A, Karogiannis N, Tzalamouras V, Parsons G, Young G, Gurunathan S, Senior R.

Eur Heart J Cardiovasc Imaging. 2017 Apr 1;18(4):415-421. doi: 10.1093/ehjci/jew211.


Biofabrication of a novel biomolecule-assisted reduced graphene oxide: an excellent biocompatible nanomaterial.

Zhang XF, Gurunathan S.

Int J Nanomedicine. 2016 Dec 8;11:6635-6649. eCollection 2016.


Differential Cytotoxic Potential of Silver Nanoparticles in Human Ovarian Cancer Cells and Ovarian Cancer Stem Cells.

Choi YJ, Park JH, Han JW, Kim E, Jae-Wook O, Lee SY, Kim JH, Gurunathan S.

Int J Mol Sci. 2016 Dec 12;17(12). pii: E2077.


Cytotoxic effects of ZnO nanoparticles on mouse testicular cells.

Han Z, Yan Q, Ge W, Liu ZG, Gurunathan S, De Felici M, Shen W, Zhang XF.

Int J Nanomedicine. 2016 Oct 11;11:5187-5203. eCollection 2016.


The clinical efficacy and long-term prognostic value of stress echocardiography in octogenarians.

Gurunathan S, Ahmed A, Pabla J, Karogiannis N, Hua A, Young G, Nalin Shah B, Senior R.

Heart. 2017 Apr;103(7):517-523. doi: 10.1136/heartjnl-2016-310026. Epub 2016 Sep 30.


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