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Items: 49

1.

Improving Microcirculatory Reperfusion Reduces Parenchymal Oxygen Radical Formation and Provides Neuroprotection.

Taskiran-Sag A, Yemisci M, Gursoy-Ozdemir Y, Erdener SE, Karatas H, Yuce D, Dalkara T.

Stroke. 2018 May;49(5):1267-1275. doi: 10.1161/STROKEAHA.118.020711. Epub 2018 Apr 18.

PMID:
29669868
2.

Cell Death Mechanisms in Stroke and Novel Molecular and Cellular Treatment Options.

Sekerdag E, Solaroglu I, Gursoy-Ozdemir Y.

Curr Neuropharmacol. 2018;16(9):1396-1415. doi: 10.2174/1570159X16666180302115544. Review.

3.

Inadequate brain glycogen or sleep increases spreading depression susceptibility.

Kilic K, Karatas H, Dönmez-Demir B, Eren-Kocak E, Gursoy-Ozdemir Y, Can A, Petit JM, Magistretti PJ, Dalkara T.

Ann Neurol. 2018 Jan;83(1):61-73. doi: 10.1002/ana.25122.

PMID:
29244233
4.

Microembolism of single cortical arterioles can induce spreading depression and ischemic injury; a potential trigger for migraine and related MRI lesions.

Dönmez-Demir B, Yemisci M, Kılıç K, Gürsoy-Özdemir Y, Söylemezoğlu F, Moskowitz M, Dalkara T.

Brain Res. 2018 Jan 15;1679:84-90. doi: 10.1016/j.brainres.2017.11.023. Epub 2017 Nov 26.

PMID:
29183666
5.

Data of indirect immunofluorescence labeling of the mouse brain sections with sera from SLE and MS patients.

Colpak AI, Balci-Peynircioglu B, Can A, Gursoy-Ozdemir Y, Lule S, Kalyoncu U, Dalkara T.

Data Brief. 2017 Sep 20;15:170-173. doi: 10.1016/j.dib.2017.09.027. eCollection 2017 Dec.

6.

Spreading Depolarization Waves in Neurological Diseases: A Short Review about its Pathophysiology and Clinical Relevance.

Taş YÇ, Solaroğlu İ, Gürsoy-Özdemir Y.

Curr Neuropharmacol. 2019;17(2):151-164. doi: 10.2174/1570159X15666170915160707. Review.

PMID:
28925885
7.

Behçet Disease serum is immunoreactive to neurofilament medium which share common epitopes to bacterial HSP-65, a putative trigger.

Lule S, Colpak AI, Balci-Peynircioglu B, Gursoy-Ozdemir Y, Peker S, Kalyoncu U, Can A, Tekin N, Demiralp D, Dalkara T.

J Autoimmun. 2017 Nov;84:87-96. doi: 10.1016/j.jaut.2017.08.002. Epub 2017 Aug 24.

PMID:
28844827
8.

A potential non-invasive glioblastoma treatment: Nose-to-brain delivery of farnesylthiosalicylic acid incorporated hybrid nanoparticles.

Sekerdag E, Lüle S, Bozdağ Pehlivan S, Öztürk N, Kara A, Kaffashi A, Vural I, Işıkay I, Yavuz B, Oguz KK, Söylemezoğlu F, Gürsoy-Özdemir Y, Mut M.

J Control Release. 2017 Sep 10;261:187-198. doi: 10.1016/j.jconrel.2017.06.032. Epub 2017 Jul 3.

PMID:
28684169
9.

Optical coherence tomography imaging of capillary reperfusion after ischemic stroke.

Lee J, Gursoy-Ozdemir Y, Fu B, Boas DA, Dalkara T.

Appl Opt. 2016 Nov 20;55(33):9526-9531. doi: 10.1364/AO.55.009526.

10.

The Role of Pericytes in Neurovascular Unit: Emphasis on Stroke.

Oztop-Cakmak O, Solaroglu I, Gursoy-Ozdemir Y.

Curr Drug Targets. 2017;18(12):1386-1391. doi: 10.2174/1389450117666160613104523. Review.

PMID:
27296313
11.

Re: "Report of Dramatic Improvement after a Lumboperitoneal Shunt Procedure in a Case of Anticoagulation Therapy-Resistant Cerebral Venous Thrombosis".

Onder H, Gursoy Ozdemir Y.

J Stroke Cerebrovasc Dis. 2016 Jun;25(6):1557-8. doi: 10.1016/j.jstrokecerebrovasdis.2016.02.033. Epub 2016 Mar 30. No abstract available.

PMID:
27038978
12.

The time course changes in expression of aquaporin 4 and aquaporin 1 following global cerebral ischemic edema in rat.

Akdemir G, Kaymaz F, Gursoy-Özdemir Y, Akalan N, Akdemir ES.

Surg Neurol Int. 2016 Jan 6;7:4. doi: 10.4103/2152-7806.173316. eCollection 2016.

13.

Reversible transverse sinus collapse in a patient with idiopathic intracranial hypertension.

Onder H, Gocmen R, Gursoy-Ozdemir Y.

J Neurointerv Surg. 2016 Apr;8(4):e16. doi: 10.1136/neurintsurg-2014-011606.rep. Epub 2015 May 20.

PMID:
25994942
14.

Reversible transverse sinus collapse in a patient with idiopathic intracranial hypertension.

Onder H, Gocmen R, Gursoy-Ozdemir Y.

BMJ Case Rep. 2015 May 15;2015. pii: bcr2014011606. doi: 10.1136/bcr-2014-011606.

15.

Systemically administered brain-targeted nanoparticles transport peptides across the blood-brain barrier and provide neuroprotection.

Yemisci M, Caban S, Gursoy-Ozdemir Y, Lule S, Novoa-Carballal R, Riguera R, Fernandez-Megia E, Andrieux K, Couvreur P, Capan Y, Dalkara T.

J Cereb Blood Flow Metab. 2015 Mar;35(3):469-75. doi: 10.1038/jcbfm.2014.220. Epub 2014 Dec 10.

16.

Poloxamer-188 and citicoline provide neuronal membrane integrity and protect membrane stability in cortical spreading depression.

Yıldırım T, Eylen A, Lule S, Erdener SE, Vural A, Karatas H, Ozveren MF, Dalkara T, Gursoy-Ozdemir Y.

Int J Neurosci. 2015;125(12):941-6. doi: 10.3109/00207454.2014.979289. Epub 2014 Dec 4.

PMID:
25340256
17.

Atypical Aicardi-Goutieres syndrome: is the WRN locus a modifier?

Lessel D, Saha B, Hisama F, Kaymakamzade B, Nurlu G, Gursoy-Özdemir Y, Thiele H, Nürnberg P, Martin GM, Kubisch C, Oshima J.

Am J Med Genet A. 2014 Oct;164A(10):2510-3. doi: 10.1002/ajmg.a.36664. Epub 2014 Jul 2.

18.

The Presence of Autoantibodies Against Vascular and Nervous Tissue in Sera From Patients with Neuro-Behçet's Disease.

Colpak Aİ, Kalyoncu U, Gürsoy Özdemir Y.

Noro Psikiyatr Ars. 2014 Jun;51(2):141-147. doi: 10.4274/npa.y6987. Epub 2014 Jun 1.

19.

An aquaporin 4 antisense oligonucleotide loaded, brain targeted nanoparticulate system design.

Kozlu S, Caban S, Yerlikaya F, Fernandez-Megia E, Novoa-Carballal R, Riguera R, Yemisci M, Gursoy-Ozdemir Y, Dalkara T, Couvreur P, Capan Y.

Pharmazie. 2014 May;69(5):340-5.

PMID:
24855824
20.

Spreading depression triggers headache by activating neuronal Panx1 channels.

Karatas H, Erdener SE, Gursoy-Ozdemir Y, Lule S, Eren-Koçak E, Sen ZD, Dalkara T.

Science. 2013 Mar 1;339(6123):1092-5. doi: 10.1126/science.1231897. Erratum in: Science. 2015 Oct 2;350(6256):aad5166. Science. 2015 Nov 20;350(6263):921.

21.

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) in two siblings with neuropsychiatric symptoms.

Dericioglu N, Vural A, Agayeva N, Basar K, Anil Yagcioglu AE, Gursoy-Ozdemir Y.

Psychosomatics. 2013 Nov-Dec;54(6):594-8. doi: 10.1016/j.psym.2012.12.002. Epub 2013 Feb 14. No abstract available.

PMID:
23414846
22.

Cell death and survival mechanisms are concomitantly active in the hippocampus of patients with mesial temporal sclerosis.

Dericioglu N, Soylemezoglu F, Gursoy-Ozdemir Y, Akalan N, Saygi S, Dalkara T.

Neuroscience. 2013 May 1;237:56-65. doi: 10.1016/j.neuroscience.2013.01.050. Epub 2013 Feb 4.

PMID:
23384610
23.
24.

Microvascular protection is essential for successful neuroprotection in stroke.

Gursoy-Ozdemir Y, Yemisci M, Dalkara T.

J Neurochem. 2012 Nov;123 Suppl 2:2-11. doi: 10.1111/j.1471-4159.2012.07938.x. Review.

25.

Transport of a caspase inhibitor across the blood-brain barrier by chitosan nanoparticles.

Yemişci M, Gürsoy-Özdemir Y, Caban S, Bodur E, Capan Y, Dalkara T.

Methods Enzymol. 2012;508:253-69. doi: 10.1016/B978-0-12-391860-4.00013-6.

PMID:
22449930
26.

Brain microvascular pericytes in health and disease.

Dalkara T, Gursoy-Ozdemir Y, Yemisci M.

Acta Neuropathol. 2011 Jul;122(1):1-9. doi: 10.1007/s00401-011-0847-6. Epub 2011 Jun 9. Review.

PMID:
21656168
27.

Thrombotic distal middle cerebral artery occlusion produced by topical FeCl(3) application: a novel model suitable for intravital microscopy and thrombolysis studies.

Karatas H, Erdener SE, Gursoy-Ozdemir Y, Gurer G, Soylemezoglu F, Dunn AK, Dalkara T.

J Cereb Blood Flow Metab. 2011 Jun;31(6):1452-60. doi: 10.1038/jcbfm.2011.8. Epub 2011 Feb 16.

28.

Megestrol acetate inhibits the expression of cytoplasmic aromatase through nuclear C/EBPβ in reperfusion injury-induced ischemic rat hippocampus.

Kelicen Ugur P, Lule S, Cincioglu M, Pekiner C, Gursoy-Ozdemir Y.

Eur J Pharmacol. 2011 Mar 11;654(3):217-25. doi: 10.1016/j.ejphar.2010.11.001. Epub 2010 Nov 27.

PMID:
21114983
29.

Alpha-synuclein aggregation induced by brief ischemia negatively impacts neuronal survival in vivo: a study in [A30P]alpha-synuclein transgenic mouse.

Unal-Cevik I, Gursoy-Ozdemir Y, Yemisci M, Lule S, Gurer G, Can A, Müller V, Kahle PJ, Dalkara T.

J Cereb Blood Flow Metab. 2011 Mar;31(3):913-23. doi: 10.1038/jcbfm.2010.170. Epub 2010 Sep 29.

30.

Lysosomal rupture, necroapoptotic interactions and potential crosstalk between cysteine proteases in neurons shortly after focal ischemia.

Kilinc M, Gürsoy-Ozdemir Y, Gürer G, Erdener SE, Erdemli E, Can A, Dalkara T.

Neurobiol Dis. 2010 Oct;40(1):293-302. doi: 10.1016/j.nbd.2010.06.003. Epub 2010 Jun 22.

PMID:
20600913
31.

Recurrent optic neuritis: clues from a long-term follow up study of recurrent and bilateral optic neuritis patients.

Kurne A, Karabudak R, Yalcin-Cakmakli G, Gursoy-Ozdemir Y, Aydin P, Ilksen-Colpak A, Lule S, Kansu T.

Eye Brain. 2010 Mar 5;2:15-20. eCollection 2010.

32.

A nanomedicine transports a peptide caspase-3 inhibitor across the blood-brain barrier and provides neuroprotection.

Karatas H, Aktas Y, Gursoy-Ozdemir Y, Bodur E, Yemisci M, Caban S, Vural A, Pinarbasli O, Capan Y, Fernandez-Megia E, Novoa-Carballal R, Riguera R, Andrieux K, Couvreur P, Dalkara T.

J Neurosci. 2009 Nov 4;29(44):13761-9. doi: 10.1523/JNEUROSCI.4246-09.2009.

33.

Pericyte contraction induced by oxidative-nitrative stress impairs capillary reflow despite successful opening of an occluded cerebral artery.

Yemisci M, Gursoy-Ozdemir Y, Vural A, Can A, Topalkara K, Dalkara T.

Nat Med. 2009 Sep;15(9):1031-7. doi: 10.1038/nm.2022. Epub 2009 Aug 30.

PMID:
19718040
34.

Changes in the expression of selenoproteins in mesial temporal lobe epilepsy patients.

Yüzbaşioğlu A, Karataş H, Gürsoy-Ozdemir Y, Saygi S, Akalan N, Söylemezoğlu F, Dalkara T, Kocaefe YC, Ozgüç M.

Cell Mol Neurobiol. 2009 Dec;29(8):1223-31. doi: 10.1007/s10571-009-9418-y.

PMID:
19499324
35.

A new model of transient focal cerebral ischemia for inducing selective neuronal necrosis.

Arsava EM, Gurer G, Gursoy-Ozdemir Y, Karatas H, Dalkara T.

Brain Res Bull. 2009 Mar 16;78(4-5):226-31. doi: 10.1016/j.brainresbull.2008.11.005. Epub 2008 Dec 6.

PMID:
19063950
36.

Astrocytes are more resistant to focal cerebral ischemia than neurons and die by a delayed necrosis.

Gürer G, Gursoy-Ozdemir Y, Erdemli E, Can A, Dalkara T.

Brain Pathol. 2009 Oct;19(4):630-41. doi: 10.1111/j.1750-3639.2008.00226.x.

PMID:
18947334
37.

Hydrogen peroxide-induced stroke: elucidation of the mechanism in vivo.

Mut M, Yemisci M, Gursoy-Ozdemir Y, Ture U.

J Neurosurg. 2009 Jan;110(1):94-100. doi: 10.3171/2008.3.17434.

PMID:
18928358
38.

VEGF protects brain against focal ischemia without increasing blood--brain permeability when administered intracerebroventricularly.

Kaya D, Gürsoy-Ozdemir Y, Yemisci M, Tuncer N, Aktan S, Dalkara T.

J Cereb Blood Flow Metab. 2005 Sep;25(9):1111-8. Erratum in: J Cereb Blood Flow Metab. 2006 Mar;26(3):447.

PMID:
15829918
39.

Mouse model of microembolic stroke and reperfusion.

Atochin DN, Murciano JC, Gürsoy-Ozdemir Y, Krasik T, Noda F, Ayata C, Dunn AK, Moskowitz MA, Huang PL, Muzykantov VR.

Stroke. 2004 Sep;35(9):2177-82. Epub 2004 Jul 15.

PMID:
15256680
40.

Apoptotic and necrotic death mechanisms are concomitantly activated in the same cell after cerebral ischemia.

Unal-Cevik I, Kilinç M, Can A, Gürsoy-Ozdemir Y, Dalkara T.

Stroke. 2004 Sep;35(9):2189-94. Epub 2004 Jul 15.

PMID:
15256676
41.

Laser speckle flowmetry for the study of cerebrovascular physiology in normal and ischemic mouse cortex.

Ayata C, Dunn AK, Gursoy-OZdemir Y, Huang Z, Boas DA, Moskowitz MA.

J Cereb Blood Flow Metab. 2004 Jul;24(7):744-55.

PMID:
15241182
42.

Loss of NeuN immunoreactivity after cerebral ischemia does not indicate neuronal cell loss: a cautionary note.

Unal-Cevik I, Kilinç M, Gürsoy-Ozdemir Y, Gurer G, Dalkara T.

Brain Res. 2004 Jul 23;1015(1-2):169-74.

PMID:
15223381
43.

Cortical spreading depression activates and upregulates MMP-9.

Gursoy-Ozdemir Y, Qiu J, Matsuoka N, Bolay H, Bermpohl D, Jin H, Wang X, Rosenberg GA, Lo EH, Moskowitz MA.

J Clin Invest. 2004 May;113(10):1447-55.

44.

Reperfusion-induced oxidative/nitrative injury to neurovascular unit after focal cerebral ischemia.

Gürsoy-Ozdemir Y, Can A, Dalkara T.

Stroke. 2004 Jun;35(6):1449-53. Epub 2004 Apr 8.

PMID:
15073398
45.

Persistent defect in transmitter release and synapsin phosphorylation in cerebral cortex after transient moderate ischemic injury.

Bolay H, Gürsoy-Ozdemir Y, Sara Y, Onur R, Can A, Dalkara T.

Stroke. 2002 May;33(5):1369-75.

PMID:
11988617
46.

Spleen damage in endotoxaemic mice: the involvement of nitric oxide.

Yilmaz G, Gursoy-Ozdemir Y, Dogan AI, Gurdal H, Gedikoglu G, Dalkara T, Guc MO.

J Physiol Pharmacol. 2001 Dec;52(4 Pt 2):729-44.

47.

Chronic daily administration of selegiline and EGb 761 increases brain's resistance to ischemia in mice.

Unal I, Gürsoy-Ozdemir Y, Bolay H, Söylemezoglu F, Saribaş O, Dalkara T.

Brain Res. 2001 Nov 2;917(2):174-81.

PMID:
11640903
48.

Role of endothelial nitric oxide generation and peroxynitrite formation in reperfusion injury after focal cerebral ischemia.

Gürsoy-Ozdemir Y, Bolay H, Saribaş O, Dalkara T.

Stroke. 2000 Aug;31(8):1974-80; discussion 1981.

PMID:
10926966
49.

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