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Items: 11


Alterations to mTORC1 signaling in the skeletal muscle differentially affect whole-body metabolism.

Guridi M, Kupr B, Romanino K, Lin S, Falcetta D, Tintignac L, Rüegg MA.

Skelet Muscle. 2016 Mar 21;6:13. doi: 10.1186/s13395-016-0084-8. eCollection 2016.


Activation of mTORC1 in skeletal muscle regulates whole-body metabolism through FGF21.

Guridi M, Tintignac LA, Lin S, Kupr B, Castets P, Rüegg MA.

Sci Signal. 2015 Nov 10;8(402):ra113. doi: 10.1126/scisignal.aab3715.


Antioxidant peroxiredoxin 6 protein rescues toxicity due to oxidative stress and cellular hypoxia in vitro, and attenuates prion-related pathology in vivo.

Asuni AA, Guridi M, Sanchez S, Sadowski MJ.

Neurochem Int. 2015 Nov;90:152-65. doi: 10.1016/j.neuint.2015.08.006. Epub 2015 Aug 8.


Blocking the apoE/Aβ interaction ameliorates Aβ-related pathology in APOE ε2 and ε4 targeted replacement Alzheimer model mice.

Pankiewicz JE, Guridi M, Kim J, Asuni AA, Sanchez S, Sullivan PM, Holtzman DM, Sadowski MJ.

Acta Neuropathol Commun. 2014 Jun 28;2:75. doi: 10.1186/s40478-014-0075-0.


Modulation of amyloid precursor protein expression reduces β-amyloid deposition in a mouse model.

Asuni AA, Guridi M, Pankiewicz JE, Sanchez S, Sadowski MJ.

Ann Neurol. 2014 May;75(5):684-99. doi: 10.1002/ana.24149. Epub 2014 Apr 28.


Sustained activation of mTORC1 in skeletal muscle inhibits constitutive and starvation-induced autophagy and causes a severe, late-onset myopathy.

Castets P, Lin S, Rion N, Di Fulvio S, Romanino K, Guridi M, Frank S, Tintignac LA, Sinnreich M, Rüegg MA.

Cell Metab. 2013 May 7;17(5):731-44. doi: 10.1016/j.cmet.2013.03.015. Epub 2013 Apr 18.


Blocking the interaction between apolipoprotein E and Aβ reduces intraneuronal accumulation of Aβ and inhibits synaptic degeneration.

Kuszczyk MA, Sanchez S, Pankiewicz J, Kim J, Duszczyk M, Guridi M, Asuni AA, Sullivan PM, Holtzman DM, Sadowski MJ.

Am J Pathol. 2013 May;182(5):1750-68. doi: 10.1016/j.ajpath.2013.01.034. Epub 2013 Mar 13.


Differential response of skeletal muscles to mTORC1 signaling during atrophy and hypertrophy.

Bentzinger CF, Lin S, Romanino K, Castets P, Guridi M, Summermatter S, Handschin C, Tintignac LA, Hall MN, Rüegg MA.

Skelet Muscle. 2013 Mar 6;3(1):6. doi: 10.1186/2044-5040-3-6.


In vivo hippocampal microdialysis reveals impairment of NMDA receptor-cGMP signaling in APP(SW) and APP(SW)/PS1(L166P) Alzheimer's transgenic mice.

Duszczyk M, Kuszczyk M, Guridi M, Lazarewicz JW, Sadowski MJ.

Neurochem Int. 2012 Dec;61(7):976-80. doi: 10.1016/j.neuint.2012.07.017. Epub 2012 Jul 27.


Single nucleotide polymorphisms in the Melanocortin 1 Receptor gene are linked with lightness of fibre colour in Peruvian Alpaca (Vicugna pacos).

Guridi M, Soret B, Alfonso L, Arana A.

Anim Genet. 2011 Dec;42(6):679-82. doi: 10.1111/j.1365-2052.2011.02205.x. Epub 2011 May 23.


Clonal Mature Adipocyte Production of Proliferative-competent Daughter Cells Requires Lipid Export Prior to Cell Division.

Chen J, Guridi M, Fernyhough ME, Jiang Z, Guan L, Hausman GJ, Dodson MV.

Int J Stem Cells. 2009 May;2(1):76-9.

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